Ohno's "peril of hemizygosity" revisited: Gene loss, dosage compensation, and mutation

Genome Biology and Evolution

Volumn 5, Issue 1, 2013, Pages 1-15

  Hall, David W ^a   Wayne, Marta L ^b  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Metabolic control theory; Sex chromosome evolution; X chromosome

Indexed keywords

EID: 84876532784     PISSN: None     EISSN: 17596653     Source Type: Journal    
DOI: 10.1093/gbe/evs106     Document Type: Article

References (53)

1. Bachtrog D. 2008. The temporal dynamics of processes underlying Y chromosome degeneration. Genetics 179:1513-1525.
2. Bachtrog D, et al. 2011. Are all sex chromosomes created equal? Trends Genet. 27:350-357.
3. Bate NJ, et al. 1994. Quantitative relationship between phenylalanine ammonia-lyase levels and phenylpropanoid accumulation in transgenic tobacco identifies a rate-determining step in natural product synthesis. Proc Natl Acad Sci U S A. 91:7608-7612.
4. Birchler JA. 2012. Claims and counterclaims of X-chromosome compensation. Nat Struct Mol Biol. 19:3-5.
5. Bull JJ. 1983. Evolution of sex determining mechanisms. Menlo Park (CA): Benjamin Cummings.
6. Carrel L,Willard FH. 2005. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434:400-404.
7. Carvalho AB. 2002. Origin and evolution of the Drosophila Y chromosome. Curr Opin Genet Dev. 12:664-668.
8. Carvalho AB, Koerich LB, Clark GA. 2009. Origin and evolution of Y chromosomes: Drosophila tales. Trends Genet. 25:270-277.
9. Charlesworth B. 1996a. Background selection and patterns of genetic diversity in Drosophila. Genet Res. 68:131-149.
10. Charlesworth B. 1996b. The evolution of chromosomal sex determination and dosage compensation. Curr Biol. 6:149-162.
11. Charlesworth B, Charlesworth D. 2000. The degeneration of Y chromosomes. Philos Trans R Soc London B Biol Sci. 355:1563-1572.
12. Charlesworth D, Charlesworth B. 1980. Sex-differences in fitness and selection for centric fusions between sex-chromosomes and autosomes. Genet Res. 35:205-214.
13. Chibalina MV, Filatov AD. 2011. Plant Y chromosome degeneration is retarded by haploid purifying selection. Curr Biol. 21:1475-1479.
14. Dykhuizen DE, Dean MA. 1990. Enzyme-Activity and fitness-evolution in solution. Trends Ecol Evol. 5:257-262.
15. Engelstadter J. 2008. Muller's ratchet and the degeneration of Y chromosomes: a simulation study. Genetics 180:957-967.
16. Fisher RA. 1930. The genetical theory of natural selection. Oxford: Oxford University Press.
17. Fisher RA. 1935. The sheltering of lethals. Am Nat. 69:446-455.
18. Gordo I, Charlesworth B. 2000. On the speed of Muller's ratchet. Genetics 156:2137-2140.
19. Gordo I, Charlesworth B. 2001. The speed of Muller's ratchet with background selection, and the degeneration of Y chromosomes. Genet Res. 78:149-161.
20. Gowen JW, Gay HE. 1934. Chromosome constitution and behavior in eversporting and mottling in Drosophila melanogaster. Genetics 19: 0189-0208.
21. Haldane JBS. 1927. A mathematical theory of natural and artificial selection. Part V. Selection and mutation. Proc Cambridge Philos Soc. 23: 838-844.
22. He XL, Zhang JZ. 2006. Why do hubs tend to be essential in protein networks? PLoS Genet. 2:826-834.
23. Kacser H, Burns AJ. 1981. The molecular basis of dominance. Genetics 97: 639-666.
24. Kaiser VB, Bachtrog D. 2010. Evolution of sex shromosomes in insects. In: Campbell A, Lichten M, Schupbach G, editors. Annual review of genetics, Vol. 44. Palo Alto (CA): Annual Reviews. p. 91-112.
25. Kaiser VB, Zhou Q, Bachtrog D. 2011. Nonrandom gene loss from the Drosophila miranda neo-Y chromosome. Genome Biol Evol. 3: 1329-1337.
26. Karn M, Penrose SL. 1952. Birth weight and gestation time in relation to maternal age, parity, and infant survival. Ann Eugen. 16:147-164.
27. Kingsolver JG, et al. 2001. The strength of phenotypic selection in natural populations. Am Nat. 157:245-261.
28. Kondrashov AS, Crow FJ. 1991. Haploidy or diploidy: which is better? Nature 351:314-315.
29. Lahn BT, Page CD. 1999. Four evolutionary strata on the human X chromosome. Science 286:964-967.
30. Lemos B, Araripe LO, Hartl LD. 2008. Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences. Science 319: 91-93.
31. Lin F, Xing K, Zhang J, He X. 2012. Expression reduction in mammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation. Proc Natl Acad Sci U S A. 109:11752-11757.
32. Lyon MF. 1961. Gene action in X-chromosome of mouse (Mus Musculus L). Nature 190:372-373.
33. Manna F, Martin G, Lenormand T. 2011. Fitness landscapes: an alternative theory for the dominance of mutation. Genetics 189:923-U303.
34. Muyle A, et al. 2012. Rapid de novo evolution of X chromosome dosage compensation in Silene latifolia, a plant with young sex chromosomes. PLoS Biol. 10:8.
35. Muller HJ. 1918. Genetic variability, twin hybrids, and constant hybrids, in a case of balanced lethal factors. Genetics 3:422-499.
36. Nguyen DK, Disteche MC. 2006. Dosage compensation of the active X chromosome in mammals. Nat Genet. 38:47-53.
37. Nicolas M, et al. 2005. A gradual process of recombination restriction in the evolutionary history of the sex chromosomes in dioecious plants. PLoS Biol. 3:47-56.
38. Ohno S. 1967. Sex chromosomes and sex-linked genes. New York: Springer-Verlag.
39. Payer B, Lee TJ. 2008. X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet. 42:733-772.
40. Pessia E, et al. 2012. Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome. Proc Natl Acad Sci U S A. 109:5346-5351.
41. Phadnis N, Fry DJ. 2005. Widespread correlations between dominance and homozygous effects of mutations: implications for theories of dominance. Genetics 171:385-392.
42. Prince EG, Kirkland D, Demuth JP. 2010. Hyperexpression of the X chromosome in both sexes results in extensive female bias of X-linked genes in the flour beetle. Genome Biol Evol. 2:336-346.
43. Rosenzweig RF. 1992a. Regulation of fitness in yeast overexpressing glycolytic- enzymes-parameters of growth and viability. Genet Res. 59: 35-48.
44. Rosenzweig RF. 1992b. Regulation of fitness in yeast overexpressing glycolytic- enzymes-responses to heat-shock and nitrogen starvation. Genet Res. 59:167-177.
45. Ross JA, Urton JR, Boland J, Shapiro MD, Peichel LC. 2009. Turnover of sex chromosomes in the stickleback fishes (Gasterosteidae). PLoS Genet. 5:e1000391.
46. Schluter D. 1988. Estimating the form of natural selection on a quantitative trait. Evolution 42:849-861.
47. Sopko R, et al. 2006. Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell. 21:319-330.
48. Veitia RA. 2002. Exploring the etiology of haploinsufficiency. Bioessays 24: 175-184.
49. Veitia RA, Bottani S, Birchler AJ. 2008. Cellular reactions to gene dosage imbalance: genomic, transcriptomic and proteomic effects. Trends Genet. 24:390-397.
50. Vicoso B, Bachtrog D. 2009. Progress and prospects toward our understanding of the evolution of dosage compensation. Chromosome Res. 17:585-602.
51. Weis AE, Abrahamson WG, Andersen CM. 1992. Variable selection on eurostas gall size.1. The extent and nature of variation in phenotypic selection. Evolution 46:1674-1697.
52. Xiong YY, et al. 2010. RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet. 42:1043-1047.
53. Yoshikawa K, et al. 2011. Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28:349-361.