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This and particularly [1] are very good entry points to the theory of Y chromosome evolution and to the ingenious experiments that use D. melanogaster to study a macroevolutionary phenomenon (the evolution of Y) "within one National Science Foundation grant period". They also cover the related issue of the evolutionary role of recombination.
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Rice W.R. Experimental tests of the adaptive significance of sexual recombination. Nat Rev Genet. 3:2002;241-251. This and particularly [1] are very good entry points to the theory of Y chromosome evolution and to the ingenious experiments that use D. melanogaster to study a macroevolutionary phenomenon (the evolution of Y) "within one National Science Foundation grant period". They also cover the related issue of the evolutionary role of recombination.
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A good review of Y degeneration theories. Besides theory, it also covers empirical studies on model systems that provide snapshots of the process of Y degeneration, such as Drosophila species bearing 'neo-X' and 'neo-Y' chromosomes.
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Charlesworth B., Charlesworth D. The degeneration of Y chromosomes. Philos Trans R Soc Lond B Biol Sci. 355:2000;1563-1572. A good review of Y degeneration theories. Besides theory, it also covers empirical studies on model systems that provide snapshots of the process of Y degeneration, such as Drosophila species bearing 'neo-X' and 'neo-Y' chromosomes.
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A high point and a good retrospective view on a line of investigation that traces back to the 1960s, when the loops of the Drosophila Y chromosome were first observed. The paper solves a long-standing mystery, by showing that a loop actually results from the transcription of a conventional coding gene that has Mbp-sized introns.
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Reugels A.M., Kurek R., Lammermann U., Bunemann H. Mega-introns in the dynein gene DhDhc7(Y) on the heterochromatic Y chromosome give rise to the giant threads loops in primary spermatocytes of Drosophila hydei. Genetics. 154:2000;759-769. A high point and a good retrospective view on a line of investigation that traces back to the 1960s, when the loops of the Drosophila Y chromosome were first observed. The paper solves a long-standing mystery, by showing that a loop actually results from the transcription of a conventional coding gene that has Mbp-sized introns.
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A blend of genomics, classical genetics and evolutionarily-minded analysis that initiated the massive identification of Y-linked genes. Pieces of these genes were found among the unmapped scaffolds produced by the WGS sequencing of the Drosophila genome, which is allowing the fast identification of new genes. The methods developed there (and in [16••] ) can be applied to identify heterochromatic genes in all genomes sequenced by WGS.
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Carvalho A.B., Lazzaro B.P., Clark A.G. Y chromosomal fertility factors kl-2 and kl-3 of Drosophila melanogaster encode dynein heavy chain polypeptides. Proc Natl Acad Sci USA. 97:2000;13239-13244. A blend of genomics, classical genetics and evolutionarily-minded analysis that initiated the massive identification of Y-linked genes. Pieces of these genes were found among the unmapped scaffolds produced by the WGS sequencing of the Drosophila genome, which is allowing the fast identification of new genes. The methods developed there (and in [16••] ) can be applied to identify heterochromatic genes in all genomes sequenced by WGS.
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A deep, scholarly account of the 'whole genome shotgun' sequencing of Drosophila. At the same time it is easy to read, and will be very useful for those interested in understanding the inner works of the WGS method. A classic that would deserve three bullets.
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Myers E.W., Sutton G.G., Delcher A.L., Dew I.M., Fasulo D.P., Flanigan M.J., Kravitz S.A., Mobarry C.M., Reinert K.H., Remington K.A., et al. A whole-genome assembly of Drosophila. Science. 287:2000;2196-2204. A deep, scholarly account of the 'whole genome shotgun' sequencing of Drosophila. At the same time it is easy to read, and will be very useful for those interested in understanding the inner works of the WGS method. A classic that would deserve three bullets.
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Myers, E.W.1
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The Drosophila genome unveiled. Besides, a very readable landmark on genetics and genomics.
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Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., et al. The genome sequence of Drosophila melanogaster. Science. 287:2000;2185-2195. The Drosophila genome unveiled. Besides, a very readable landmark on genetics and genomics.
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Adams, M.D.1
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A good review on the human Y, written by some of the key players.
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Lahn B.T., Pearson N.M., Jegalian K. The human Y chromosome, in the light of evolution. Nat Rev Genet. 2:2001;207-216. A good review on the human Y, written by some of the key players.
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Lahn, B.T.1
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A careful cytogenetic study that shows in a non-partisan way how faint may be the difference between B and Y chromosomes. Look at Figure 11 and Table 2, and judge for yourself: most people will swear that Rhinocola aceris has a Y chromosome. If the authors had not found other populations devoid of this fake Y (which shows that it actually is a dispensable, X-pairing B-chromosome) one would easily conclude that R. aceris has a XY sex-chromosome system, instead of X0.
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Nokkala S., Kuznetsova V., Maryanska-Nadachowska A. Achiasmate segregation of a B chromosome from the X chromosome in two species of psyllids (Psylloidea, Homoptera). Genetica. 108:2000;181-189. A careful cytogenetic study that shows in a non-partisan way how faint may be the difference between B and Y chromosomes. Look at Figure 11 and Table 2, and judge for yourself: most people will swear that Rhinocola aceris has a Y chromosome. If the authors had not found other populations devoid of this fake Y (which shows that it actually is a dispensable, X-pairing B-chromosome) one would easily conclude that R. aceris has a XY sex-chromosome system, instead of X0.
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A very readable, witty review on sperm competition in Drosophila, with emphasis on the maintenance of polymorphisms. The source of 'random' parameters used in computer simulations of sperm competition (the scores from the US National Hockey League) is particularly apt and funny.
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Clark A.G. Sperm competition and the maintenance of polymorphism. Heredity. 88:2002;148-153. A very readable, witty review on sperm competition in Drosophila, with emphasis on the maintenance of polymorphisms. The source of 'random' parameters used in computer simulations of sperm competition (the scores from the US National Hockey League) is particularly apt and funny.
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Laboratory experiments showed that Y chromosome polymorphism is a major determinant of male fitness in Drosophila. This remarkable paper is sharply at odds with theoretical expectations and some previous experimental data [38,39], and hence is likely to stimulate more work on both fronts
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Chippindale A.K., Rice W.R. Y chromosome polymorphism is a strong determinant of male fitness in Drosophila melanogaster. Proc Natl Acad Sci USA. 98:2001;5677-5682. Laboratory experiments showed that Y chromosome polymorphism is a major determinant of male fitness in Drosophila. This remarkable paper is sharply at odds with theoretical expectations and some previous experimental data [38,39], and hence is likely to stimulate more work on both fronts.
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