메뉴 건너뛰기




Volumn 42, Issue 6, 2013, Pages 1961-1972

Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer

Author keywords

Acetylation; Cancer; Glycolysis; Hypoxia inducible factor; Metabolism; Oxidative phosphorylation; P300 CBP associated factor; P53

Indexed keywords

ACYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HYPOXIA INDUCIBLE FACTOR 1; LACTIC ACID; PROTEIN P53; TRANSCRIPTION FACTOR;

EID: 84876526130     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.1907     Document Type: Article
Times cited : (25)

References (33)
  • 1
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • DOI 10.1016/j.ccr.2006.04.023, PII S1535610806001450
    • Fantin VR, St-Pierre J and Leder P: Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9: 425-434, 2006. (Pubitemid 43832190)
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 3
    • 60249088344 scopus 로고    scopus 로고
    • Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense
    • Olovnikov IA, Kravchenko JE and Chumakov PM: Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense. Semin Cancer Biol 19: 32-41, 2009.
    • (2009) Semin Cancer Biol , vol.19 , pp. 32-41
    • Olovnikov, I.A.1    Kravchenko, J.E.2    Chumakov, P.M.3
  • 4
    • 57449097020 scopus 로고    scopus 로고
    • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
    • Sonveaux P, Végran F, Schroeder T, et al: Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest 118: 3930-3942, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 3930-3942
    • Sonveaux, P.1    Végran, F.2    Schroeder, T.3
  • 5
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's achilles' heel
    • DOI 10.1016/j.ccr.2008.05.005, PII S1535610808001608
    • Kroemer G and Pouyssegur J: Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13: 472-482, 2008. (Pubitemid 351766797)
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 6
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I, Cairns RA, Fontana L, Lim AL and Denko NC: HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 3: 187-197, 2006.
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 7
    • 35448961940 scopus 로고    scopus 로고
    • HIF-1 mediates the Warburg effect in clear cell renal carcinoma
    • DOI 10.1007/s10863-007-9081-2, Special Topic: The Warburg Effect: Its Continued Impact on Cancer Research into the 21st Century
    • Semenza G: HIF-1 mediates the Warburg effect in clear cell renal carcinoma. J Bioenerg Biomembr 39: 231-234, 2007. (Pubitemid 47619375)
    • (2007) Journal of Bioenergetics and Biomembranes , vol.39 , Issue.3 , pp. 231-234
    • Semenza, G.L.1
  • 10
    • 84863244013 scopus 로고    scopus 로고
    • The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy
    • Shen L, Sun X, Fu Z, Yang G, Li J and Yao L: The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy. Clin Cancer Res 18: 1561-1567, 2012.
    • (2012) Clin Cancer Res , vol.18 , pp. 1561-1567
    • Shen, L.1    Sun, X.2    Fu, Z.3    Yang, G.4    Li, J.5    Yao, L.6
  • 11
    • 33745149291 scopus 로고    scopus 로고
    • P53 regulates mitochon-drial respiration
    • Matoba S, Kang J-G, Patino WD, et al: p53 regulates mitochon-drial respiration. Science 312: 1650-1653, 2006.
    • (2006) Science , vol.312 , pp. 1650-1653
    • Matoba, S.1    Kang, J.-G.2    Patino, W.D.3
  • 12
    • 70350575440 scopus 로고    scopus 로고
    • Modulation of intra-cellular ROS levels by TIGAR controls autophagy
    • Bensaad K, Cheung EC and Vousden KH: Modulation of intra-cellular ROS levels by TIGAR controls autophagy. EMBO J 28: 3015-3026, 2009.
    • (2009) EMBO J , vol.28 , pp. 3015-3026
    • Bensaad, K.1    Cheung, E.C.2    Vousden, K.H.3
  • 13
    • 77953871095 scopus 로고    scopus 로고
    • Assembly factors and ATP-dependent proteases in cytochrome c oxidase biogenesis
    • Stiburek L and Zeman J: Assembly factors and ATP-dependent proteases in cytochrome c oxidase biogenesis. Biochim Biophys Acta 1797: 1149-1158, 2010.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 1149-1158
    • Stiburek, L.1    Zeman, J.2
  • 15
    • 59449084996 scopus 로고    scopus 로고
    • Structural and biochemical studies of TIGAR (Tp53-induced glycolysis and apoptosis regulator)
    • Li H and Jogl G: Structural and biochemical studies of TIGAR (Tp53-induced glycolysis and apoptosis regulator). J Biol Chem 284: 1748-1754, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 1748-1754
    • Li, H.1    Jogl, G.2
  • 17
    • 53249088036 scopus 로고    scopus 로고
    • PCAF is an HIF-1[alpha] co-factor that regulates p53 transcriptional activity in hypoxia
    • Xenaki G, Ontikatze T, Rajendran R, et al: PCAF is an HIF-1[alpha] co-factor that regulates p53 transcriptional activity in hypoxia. Oncogene 27: 5785-5796, 2008.
    • (2008) Oncogene , vol.27 , pp. 5785-5796
    • Xenaki, G.1    Ontikatze, T.2    Rajendran, R.3
  • 18
    • 77955499804 scopus 로고    scopus 로고
    • Sirtuin 1 modulates cellular responses to hypoxia by deacety-lating hypoxia-inducible factor 1α
    • Lim J-H, Lee Y-M, Chun Y-S, Chen J, Kim J-E and Park J-W: Sirtuin 1 modulates cellular responses to hypoxia by deacety-lating hypoxia-inducible factor 1α. Mol Cell 38: 864-878, 2010.
    • (2010) Mol Cell , vol.38 , pp. 864-878
    • Lim, J.-H.1    Lee, Y.-M.2    Chun, Y.-S.3    Chen, J.4    Kim, J.-E.5    Park, J.-W.6
  • 21
    • 77949887506 scopus 로고    scopus 로고
    • Mammalian sirtuins: Biological insights and disease relevance
    • Haigis MC and Sinclair DA: Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol 5: 253-295, 2010.
    • (2010) Annu Rev Pathol , vol.5 , pp. 253-295
    • Haigis, M.C.1    Sinclair, D.A.2
  • 23
    • 77955470822 scopus 로고    scopus 로고
    • Metabolism and proliferation share common regulatory pathways in cancer cells
    • Fritz V and Fajas L: Metabolism and proliferation share common regulatory pathways in cancer cells. Oncogene 29: 4369-4377, 2010.
    • (2010) Oncogene , vol.29 , pp. 4369-4377
    • Fritz, V.1    Fajas, L.2
  • 24
    • 0033636892 scopus 로고    scopus 로고
    • Acetylation regulates transcription factor activity at multiple levels
    • Soutoglou E, Katrakili N and Talianidis I: Acetylation regulates transcription factor activity at multiple levels. Mol Cell 5: 745-751, 2000.
    • (2000) Mol Cell , vol.5 , pp. 745-751
    • Soutoglou, E.1    Katrakili, N.2    Talianidis, I.3
  • 25
    • 0034892854 scopus 로고    scopus 로고
    • A TPR motif cofactor contributes to p300 activity in the p53 response
    • DOI 10.1016/S1097-2765(01)00277-5
    • Demonacos C, Krstic-Demonacos M and La Thangue NB: A TPR motif co-factor contributes to p300 activity in the p53 response. Mol Cell 8: 71-84, 2001. (Pubitemid 32772906)
    • (2001) Molecular Cell , vol.8 , Issue.1 , pp. 71-84
    • Demonacos, C.1    Krstic-Demonacos, M.2    La Thangue, N.B.3
  • 26
    • 77952415166 scopus 로고    scopus 로고
    • Bioenergetics, the origins of complexity, and the ascent of man
    • Wallace DC: Bioenergetics, the origins of complexity, and the ascent of man. Proc Natl Acad Sci USA 107: 8947-8953, 2010.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8947-8953
    • Wallace, D.C.1
  • 27
    • 34249681337 scopus 로고    scopus 로고
    • P53: New roles in metabolism
    • DOI 10.1016/j.tcb.2007.04.004, PII S0962892407000955
    • Bensaad K and Vousden KH: p53: new roles in metabolism. Trends Cell Biol 17: 286-291, 2007. (Pubitemid 46829848)
    • (2007) Trends in Cell Biology , vol.17 , Issue.6 , pp. 286-291
    • Bensaad, K.1    Vousden, K.H.2
  • 28
    • 0037716990 scopus 로고    scopus 로고
    • Mitochondrial impairment in p53-deficient human cancer cells
    • DOI 10.1093/mutage/18.3.287
    • Zhou S, Kachhap S and Singh KK: Mitochondrial impairment in p53-defcient human cancer cells. Mutagenesis 18: 287-292, 2003. (Pubitemid 36592423)
    • (2003) Mutagenesis , vol.18 , Issue.3 , pp. 287-292
    • Zhou, S.1    Kachhap, S.2    Singh, K.K.3
  • 29
    • 1942506067 scopus 로고    scopus 로고
    • The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
    • DOI 10.1158/0008-5472.CAN-03-0846
    • Schwartzenberg-Bar-Yoseph F, Armoni M and Karnieli E: The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res 64: 2627-2633, 2004. (Pubitemid 38523921)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2627-2633
    • Schwartzenberg-Bar-Yoseph, F.1    Armoni, M.2    Karnieli, E.3
  • 31
    • 67349131613 scopus 로고    scopus 로고
    • Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2, 6-bisphos-phatases in cancer
    • Yalcin A, Telang S, Clem B and Chesney J: Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2, 6-bisphos-phatases in cancer. Exp Mol Pathol 86: 174-179, 2009.
    • (2009) Exp Mol Pathol , vol.86 , pp. 174-179
    • Yalcin, A.1    Telang, S.2    Clem, B.3    Chesney, J.4
  • 32
    • 33747505788 scopus 로고    scopus 로고
    • 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis
    • DOI 10.1097/01.mco.0000241661.15514.fb, PII 0007519720060900000002
    • Chesney J: 6-phosphofructo-2-kinase/fructose-2, 6-bisphospha-tase and tumor cell glycolysis. Curr Opin Clin Nutr Metab Care 9: 535-539, 2006. (Pubitemid 44258026)
    • (2006) Current Opinion in Clinical Nutrition and Metabolic Care , vol.9 , Issue.5 , pp. 535-539
    • Chesney, J.1
  • 33
    • 77649277719 scopus 로고    scopus 로고
    • Cancer as a metabolic disease
    • Seyfried T and Shelton L: Cancer as a metabolic disease. Nutr Metab 7: 7, 2010.
    • Nutr Metab , vol.7 , Issue.7 , pp. 2010
    • Seyfried, T.1    Shelton, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.