-
1
-
-
33847220364
-
Melanoma biology and new targeted therapy
-
17314971 10.1038/nature05661 1:CAS:528:DC%2BD2sXhvFGiu7g%3D
-
V. Gray-Schopfer, C. Wellbrock, R. Marais, Melanoma biology and new targeted therapy. Nature 445, 851-857 (2007)
-
(2007)
Nature
, vol.445
, pp. 851-857
-
-
Gray-Schopfer, V.1
Wellbrock, C.2
Marais, R.3
-
2
-
-
79957541238
-
The evolving role of radiation therapy in the management of malignant melanoma
-
21489712 10.1016/j.ijrobp.2010.12.071
-
N. Khan, M.K. Khan, A. Almasan, A.D. Singh, R. Macklis, The evolving role of radiation therapy in the management of malignant melanoma. Int. J. Radiat. Oncol. Biol. Phys. 80, 645-654 (2011)
-
(2011)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.80
, pp. 645-654
-
-
Khan, N.1
Khan, M.K.2
Almasan, A.3
Singh, A.D.4
Macklis, R.5
-
3
-
-
0015598413
-
Repair of potentially lethal radiation damage in vitro and in vivo
-
4684814 1:STN:280:DyaE3s%2FoslCmsg%3D%3D
-
J.B. Little, G.M. Hahn, E. Frindel, M. Tubiana, Repair of potentially lethal radiation damage in vitro and in vivo. Radiology 106, 689-694 (1973)
-
(1973)
Radiology
, vol.106
, pp. 689-694
-
-
Little, J.B.1
Hahn, G.M.2
Frindel, E.3
Tubiana, M.4
-
4
-
-
35048869343
-
A higher radiotherapy dose is associated with more durable palliation and longer survival in patients with metastatic melanoma
-
17721993 10.1002/cncr.22988
-
K.R. Olivier, S.E. Schild, C.G. Morris, P.D. Brown, S.N. Markovic, A higher radiotherapy dose is associated with more durable palliation and longer survival in patients with metastatic melanoma. Cancer 110, 1791-1795 (2007)
-
(2007)
Cancer
, vol.110
, pp. 1791-1795
-
-
Olivier, K.R.1
Schild, S.E.2
Morris, C.G.3
Brown, P.D.4
Markovic, S.N.5
-
5
-
-
0034475027
-
The molecular control of DNA damage-induced cell death
-
11303908 10.1023/A:1009617727938 1:CAS:528:DC%2BD3MXisV2lurk%3D
-
L. Coultas, A. Strasser, The molecular control of DNA damage-induced cell death. Apoptosis 5, 491-507 (2000)
-
(2000)
Apoptosis
, vol.5
, pp. 491-507
-
-
Coultas, L.1
Strasser, A.2
-
6
-
-
59649090207
-
The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair
-
19038467 10.1016/j.radonc.2008.10.019 1:CAS:528:DC%2BD1MXhvFGkt7Y%3D
-
U. Kasten-Pisula, A. Menegakis, I. Brammer, K. Borgmann, W.Y. Mansour, S. Degenhardt, M. Krause, A. Schreiber, J. Dahm-Daphi, C. Petersen, E. Dikomey, M. Baumann, The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair. Radiother. Oncol. 90, 257-264 (2009)
-
(2009)
Radiother. Oncol.
, vol.90
, pp. 257-264
-
-
Kasten-Pisula, U.1
Menegakis, A.2
Brammer, I.3
Borgmann, K.4
Mansour, W.Y.5
Degenhardt, S.6
Krause, M.7
Schreiber, A.8
Dahm-Daphi, J.9
Petersen, C.10
Dikomey, E.11
Baumann, M.12
-
7
-
-
84857910490
-
DNA damage by X-rays and their impact on replication processes
-
22326574 10.1016/j.radonc.2012.01.005 1:CAS:528:DC%2BC38XjsVCgsLo%3D
-
A.C. Parplys, E. Petermann, C. Petersen, E. Dikomey, K. Borgmann, DNA damage by X-rays and their impact on replication processes. Radiother. Oncol. 102, 466-471 (2012)
-
(2012)
Radiother. Oncol.
, vol.102
, pp. 466-471
-
-
Parplys, A.C.1
Petermann, E.2
Petersen, C.3
Dikomey, E.4
Borgmann, K.5
-
8
-
-
84856019858
-
The DNA damage response and cancer therapy
-
22258607 10.1038/nature10760 1:CAS:528:DC%2BC38Xps1GmsQ%3D%3D
-
C.J. Lord, A. Ashworth, The DNA damage response and cancer therapy. Nature 481, 287-294 (2012)
-
(2012)
Nature
, vol.481
, pp. 287-294
-
-
Lord, C.J.1
Ashworth, A.2
-
9
-
-
80655127826
-
The role of homologous recombination in radiation-induced double-strand break repair
-
21737170 10.1016/j.radonc.2011.06.019 1:CAS:528:DC%2BC3MXhsVahtLjP
-
P.A. Jeggo, V. Geuting, M. Löbrich, The role of homologous recombination in radiation-induced double-strand break repair. Radiother. Oncol. 101, 7-12 (2011)
-
(2011)
Radiother. Oncol.
, vol.101
, pp. 7-12
-
-
Jeggo, P.A.1
Geuting, V.2
Löbrich, M.3
-
10
-
-
38549145569
-
Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2)
-
18182996 10.1038/sj.bjc.6604084
-
M. Pérez-Caro, C. Bermejo-Rodríguez, I. González-Herrero, M. Sánchez-Beato, M.A. Piris, I. Sánchez-García, Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2). Br. J. Cancer 98, 480-488 (2008)
-
(2008)
Br. J. Cancer
, vol.98
, pp. 480-488
-
-
Pérez-Caro, M.1
Bermejo-Rodríguez, C.2
González-Herrero, I.3
Sánchez-Beato, M.4
Piris, M.A.5
Sánchez-García, I.6
-
11
-
-
0036513626
-
The snail superfamily of zinc-finger transcription factors
-
11994736 10.1038/nrm757 1:CAS:528:DC%2BD38XitFShsL4%3D
-
M.A. Nieto, The snail superfamily of zinc-finger transcription factors. Nat. Rev. Mol. Cell Biol. 3, 155-166 (2002)
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 155-166
-
-
Nieto, M.A.1
-
12
-
-
0030949081
-
Slug, a zinc finger gene previously implicated in the early patterning of the mesoderm and the neural crest, is also involved in chick limb development
-
9165129 1:CAS:528:DyaK2sXjs1Krsro%3D
-
M.A. Ros, M. Sefton, M.A. Nieto, Slug, a zinc finger gene previously implicated in the early patterning of the mesoderm and the neural crest, is also involved in chick limb development. Development 124, 1821-1829 (1997)
-
(1997)
Development
, vol.124
, pp. 1821-1829
-
-
Ros, M.A.1
Sefton, M.2
Nieto, M.A.3
-
13
-
-
0031005659
-
The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
-
9182671 10.1083/jcb.137.6.1403 1:CAS:528:DyaK2sXjvF2jtLY%3D
-
P. Savagner, K.M. Yamada, J.P. Thiery, The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J. Cell. Biol. 137, 1403-1419 (1997)
-
(1997)
J. Cell. Biol.
, vol.137
, pp. 1403-1419
-
-
Savagner, P.1
Yamada, K.M.2
Thiery, J.P.3
-
14
-
-
25844508786
-
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
-
16142232 10.1038/ng1634 1:CAS:528:DC%2BD2MXhtVCntL7K
-
P.B. Gupta, C. Kuperwasser, J.P. Brunet, S. Ramaswamy, W.L. Kuo, J.W. Gray, S.P. Naber, R.A. Weinberg, The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat. Genet. 37, 1047-1054 (2005)
-
(2005)
Nat. Genet.
, vol.37
, pp. 1047-1054
-
-
Gupta, P.B.1
Kuperwasser, C.2
Brunet, J.P.3
Ramaswamy, S.4
Kuo, W.L.5
Gray, J.W.6
Naber, S.P.7
Weinberg, R.A.8
-
15
-
-
15544362735
-
Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level
-
15790452 10.1016/j.ygyno.2004.12.043 1:CAS:528:DC%2BD2MXis1Grsb4%3D
-
N.K.K.A. Kurrey, S.A. Bapat, Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level. Gynecol. Oncol. 97, 155-165 (2005)
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 155-165
-
-
Kurrey, N.1
Bapat, S.A.2
-
16
-
-
21244437500
-
Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
-
15864483 10.1245/ASO.2005.04.010
-
T.A. Martin, A. Goyal, G. Watkins, W.G. Jiang, Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann. Surg. Oncol. 12, 488-496 (2005)
-
(2005)
Ann. Surg. Oncol.
, vol.12
, pp. 488-496
-
-
Martin, T.A.1
Goyal, A.2
Watkins, G.3
Jiang, W.G.4
-
17
-
-
18844369324
-
SLUG in cancer development
-
15735690 10.1038/sj.onc.1208505
-
P.A. Pérez-Mancera, I. González-Herrero, M. Pérez-Caro, N. Gutiérrez-Cianca, T. Flores, A. Gutiérrez-Adán, B. Pintado, M. Sánchez-Martín, I. Sánchez-García, SLUG in cancer development. Oncogene 24, 3073-3082 (2005)
-
(2005)
Oncogene
, vol.24
, pp. 3073-3082
-
-
Pérez-Mancera, P.A.1
González-Herrero, I.2
Pérez-Caro, M.3
Gutiérrez-Cianca, N.4
Flores, T.5
Gutiérrez-Adán, A.6
Pintado, B.7
Sánchez-Martín, M.8
Sánchez-García, I.9
-
18
-
-
84864080019
-
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion
-
22911700 10.1371/journal.pone.0040378 1:CAS:528:DC%2BC38XhtFSkt7jJ
-
N. Fenouille, M. Tichet, M. Dufies, A. Pottier, A. Mogha, J.K. Soo, S. Rocchi, A. Mallavialle, M.D. Galibert, A. Khammari, J.P. Lacour, R. Ballotti, M. Deckert, S. Tartare-Deckert, The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion. PLoS One 7, e40378 (2012)
-
(2012)
PLoS One
, vol.7
, pp. 40378
-
-
Fenouille, N.1
Tichet, M.2
Dufies, M.3
Pottier, A.4
Mogha, A.5
Soo, J.K.6
Rocchi, S.7
Mallavialle, A.8
Galibert, M.D.9
Khammari, A.10
Lacour, J.P.11
Ballotti, R.12
Deckert, M.13
Tartare-Deckert, S.14
-
19
-
-
4344662447
-
Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
-
15314165 10.1128/MCB.24.17.7559-7566.2004 1:CAS:528:DC%2BD2cXntVKhur8%3D
-
M. Kajita, K.N. McClinic, P.A. Wade, Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Mol. Cell. Biol. 24, 7559-7566 (2004)
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7559-7566
-
-
Kajita, M.1
McClinic, K.N.2
Wade, P.A.3
-
20
-
-
19044372843
-
Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo
-
12398892 10.1016/S1535-6108(02)00155-1
-
A. Inoue, M.G. Seidel, W. Wu, S. Kamizono, A.A. Ferrando, R.T. Bronson, H. Iwasaki, K. Akashi, A. Morimoto, J.K. Hitzler, T.I. Pestina, C.W. Jackson, R. Tanaka, M.J. Chong, P.J. McKinnon, T. Inukai, G.C. Grosveld, A.T. Look, Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo. Cancer Cell. 2, 279-288 (2002)
-
(2002)
Cancer Cell.
, vol.2
, pp. 279-288
-
-
Inoue, A.1
Seidel, M.G.2
Wu, W.3
Kamizono, S.4
Ferrando, A.A.5
Bronson, R.T.6
Iwasaki, H.7
Akashi, K.8
Morimoto, A.9
Hitzler, J.K.10
Pestina, T.I.11
Jackson, C.W.12
Tanaka, R.13
Chong, M.J.14
McKinnon, P.J.15
Inukai, T.16
Grosveld, G.C.17
Look, A.T.18
-
21
-
-
0038713805
-
The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug
-
12833143 10.1038/sj.onc.1206467
-
J. Pérez-Losada, M. Sánchez-Martín, M. Pérez-Caro, P.A. Pérez-Mancera, I. Sánchez-García, The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug. Oncogene 22, 4205-4211 (2003)
-
(2003)
Oncogene
, vol.22
, pp. 4205-4211
-
-
Pérez-Losada, J.1
Sánchez-Martín, M.2
Pérez-Caro, M.3
Pérez-Mancera, P.A.4
Sánchez-García, I.5
-
22
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
2359136 10.1093/jnci/82.13.1107 1:CAS:528:DyaK3cXltVylsL8%3D
-
P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, M.R. Boyd, New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 82, 1107-1112 (1990)
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
23
-
-
0037364872
-
Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies
-
12655440 1:CAS:528:DC%2BD3sXit12mt7w%3D
-
B. Pauwels, A.E. Korst, C.M. de Pooter, G.G. Pattyn, H.A. Lambrechts, M.F. Baay, F. Lardon, J.B. Vermorken, Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies. Cancer Chemother. Pharmacol. 51, 221-226 (2003)
-
(2003)
Cancer Chemother. Pharmacol.
, vol.51
, pp. 221-226
-
-
Pauwels, B.1
Korst, A.E.2
De Pooter, C.M.3
Pattyn, G.G.4
Lambrechts, H.A.5
Baay, M.F.6
Lardon, F.7
Vermorken, J.B.8
-
24
-
-
84907107465
-
Radiation biology of malignant melanoma
-
3010642 10.3109/02841868609136368 1:STN:280:DyaL283htFehtw%3D%3D
-
E.K. Rofstad, Radiation biology of malignant melanoma. Acta Radiol. Oncol. 25, 1-10 (1986)
-
(1986)
Acta Radiol. Oncol.
, vol.25
, pp. 1-10
-
-
Rofstad, E.K.1
-
25
-
-
0038793948
-
Apoptosis and melanoma chemoresistance
-
12789290 10.1038/sj.onc.1206454 1:CAS:528:DC%2BD3sXkt12quro%3D
-
M.S. Soengas, S.W. Lowe, Apoptosis and melanoma chemoresistance. Oncogene 22, 3138-3151 (2003)
-
(2003)
Oncogene
, vol.22
, pp. 3138-3151
-
-
Soengas, M.S.1
Lowe, S.W.2
-
26
-
-
84655176658
-
Slug inhibition upregulates radiation-induced PUMA activity leading to apoptosis in cholangiocarcinomas
-
21120639 10.1007/s12032-010-9759-x
-
K. Zhang, B. Zhang, Y. Lu, C. Sun, W. Zhao, X. Jiao, J. Hu, P. Mu, H. Lu, C. Zhou, Slug inhibition upregulates radiation-induced PUMA activity leading to apoptosis in cholangiocarcinomas. Med. Oncol. 28(Suppl 1), S301-S309 (2011)
-
(2011)
Med. Oncol.
, vol.28
, Issue.SUPPL. 1
-
-
Zhang, K.1
Zhang, B.2
Lu, Y.3
Sun, C.4
Zhao, W.5
Jiao, X.6
Hu, J.7
Mu, P.8
Lu, H.9
Zhou, C.10
-
27
-
-
77952091768
-
TGM2 is a novel marker for prognosis and therapeutic target in colorectal cancer
-
20033322 10.1245/s10434-009-0865-y
-
N. Miyoshi, H. Ishii, K. Mimori, F. Tanaka, T. Hitora, M. Tei, M. Sekimoto, Y. Doki, M. Mori, TGM2 is a novel marker for prognosis and therapeutic target in colorectal cancer. Ann. Surg. Oncol. 17, 967-972 (2010)
-
(2010)
Ann. Surg. Oncol.
, vol.17
, pp. 967-972
-
-
Miyoshi, N.1
Ishii, H.2
Mimori, K.3
Tanaka, F.4
Hitora, T.5
Tei, M.6
Sekimoto, M.7
Doki, Y.8
Mori, M.9
-
28
-
-
34548399498
-
Transglutaminase-mediated activation of nuclear transcription factor-kappaB in cancer cells: A new therapeutic opportunity
-
17896921 10.2174/156800907781662275 1:CAS:528:DC%2BD2sXhtV2gtrjE
-
A. Verma, K. Mehta, Transglutaminase-mediated activation of nuclear transcription factor-kappaB in cancer cells: a new therapeutic opportunity. Curr. Cancer Drug Targets 7, 559-565 (2007)
-
(2007)
Curr. Cancer Drug Targets
, vol.7
, pp. 559-565
-
-
Verma, A.1
Mehta, K.2
-
29
-
-
33646858986
-
Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells
-
16449978 10.1038/sj.onc.1209324 1:CAS:528:DC%2BD28Xks1OrsLw%3D
-
J.F. Herman, L.S. Mangala, K. Mehta, Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells. Oncogene 25, 3049-3058 (2006)
-
(2006)
Oncogene
, vol.25
, pp. 3049-3058
-
-
Herman, J.F.1
Mangala, L.S.2
Mehta, K.3
-
30
-
-
78149462058
-
Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells
-
10.1371/journal.pone.0013390
-
A. Kumar, J. Xu, S. Brady, H. Gao, D. Yu, J. Reuben, K. Mehta, Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells. PLoS One 50, e13390 (2010)
-
(2010)
PLoS One
, vol.50
, pp. 13390
-
-
Kumar, A.1
Xu, J.2
Brady, S.3
Gao, H.4
Yu, D.5
Reuben, J.6
Mehta, K.7
-
31
-
-
33746041843
-
Implications of tissue transglutaminase expression in malignant melanoma
-
16818508 10.1158/1535-7163.MCT-06-0083 1:CAS:528:DC%2BD28XmsVams70%3D
-
J.Y. Fok, S. Ekmekcioglu, K. Mehta, Implications of tissue transglutaminase expression in malignant melanoma. Mol. Cancer Ther. 5, 1493-1503 (2006)
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 1493-1503
-
-
Fok, J.Y.1
Ekmekcioglu, S.2
Mehta, K.3
-
32
-
-
27744547091
-
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
-
16286009 10.1016/j.cell.2005.09.029 1:CAS:528:DC%2BD2MXht1yktrjO
-
W.S. Wu, S. Heinrichs, D. Xu, S.P. Garrison, G.P. Zambetti, J.M. Adams, A.T. Look, Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 123, 641-653 (2005)
-
(2005)
Cell
, vol.123
, pp. 641-653
-
-
Wu, W.S.1
Heinrichs, S.2
Xu, D.3
Garrison, S.P.4
Zambetti, G.P.5
Adams, J.M.6
Look, A.T.7
-
33
-
-
34447136179
-
Short interfering RNA directed against the SLUG gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine
-
17641412 1:CAS:528:DC%2BD2sXnt1Khurs%3D
-
I. Vannini, M. Bonafe, A. Tesei, M. Rosetti, F. Fabbri, G. Storci, P. Ulivi, G. Brigliadori, D. Amadori, W. Zoli, Short interfering RNA directed against the SLUG gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine. Cell. Oncol. 29, 279-287 (2007)
-
(2007)
Cell. Oncol.
, vol.29
, pp. 279-287
-
-
Vannini, I.1
Bonafe, M.2
Tesei, A.3
Rosetti, M.4
Fabbri, F.5
Storci, G.6
Ulivi, P.7
Brigliadori, G.8
Amadori, D.9
Zoli, W.10
-
34
-
-
79251610744
-
RNA interference targeting Slug increases cholangiocarcinoma cell sensitivity to cisplatin via upregulating PUMA
-
21339993 10.3390/ijms12010385 1:CAS:528:DC%2BC3MXhtFOhsrs%3D
-
K. Zhang, D. Chen, X. Wang, S. Zhang, J. Wang, Y. Gao, B. Yan, RNA interference targeting Slug increases cholangiocarcinoma cell sensitivity to cisplatin via upregulating PUMA. Int. J. Mol. Sci. 12, 385-400 (2011)
-
(2011)
Int. J. Mol. Sci.
, vol.12
, pp. 385-400
-
-
Zhang, K.1
Chen, D.2
Wang, X.3
Zhang, S.4
Wang, J.5
Gao, Y.6
Yan, B.7
-
35
-
-
77954695982
-
Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide
-
20418652 10.3858/emm.2010.42.6.044 1:CAS:528:DC%2BC3cXovVWls7o%3D
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H.S. Cha, E.K. Bae, J.K. Ahn, J. Lee, K.S. Ahn, E.M. Koh, Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide. Exp. Mol. Med. 42, 428-436 (2010)
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(2010)
Exp. Mol. Med.
, vol.42
, pp. 428-436
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Cha, H.S.1
Bae, E.K.2
Ahn, J.K.3
Lee, J.4
Ahn, K.S.5
Koh, E.M.6
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