An animal model of marginal iodine deficiency during development: The thyroid axis and neurodevelopmental outcome

Toxicological Sciences

Volumn 132, Issue 1, 2013, Pages 177-195

  Gilbert, Mary E ^a   Hedge, Joan M ^a   Valentín Blasini, Liza ^b   Blount, Benjamin C ^b   Kannan, Kurunthachalam ^c   Tietge, Joseph ^a   Zoeller, R Thomas ^d   Crofton, Kevin M ^a   Jarrett, Jeffrey M ^b   Fisher, Jeffrey W ^e  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

^e NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

BBDR; Biologically based dose response models; Hippocampus; Hypothyroidism; Iodine; Learning; Neurodevelopment; Synaptic function; Thyroid

Indexed keywords

CASEIN; IODINE; POTASSIUM IODATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREEDING; CONTROLLED STUDY; DIET; FEAR; FEMALE; GESTATIONAL AGE; IODINE DEFICIENCY; LACTATION; LEARNING; MARE; MARGINAL IODINE DEFICIENCY; MAZE TEST; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; NONHUMAN; PERINATAL PERIOD; PROGENY; RAT; SURGICAL TECHNIQUE; SYNAPTIC TRANSMISSION; THYROID FUNCTION; THYROID GLAND; WEANING;

ANIMALS; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; DEFICIENCY DISEASES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IODINE; PREGNANCY; RATS; RATS, LONG-EVANS; STARTLE REACTION; THYROID GLAND;

ANIMALIA; RATTUS;

EID: 84876462720     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs335     Document Type: Article

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