Impact of low-level thyroid hormone disruption induced by propylthiouracil on brain development and function

Toxicological Sciences

Volumn 124, Issue 2, 2011, Pages 432-445

  Gilbert, Mary E ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Brain development; Dentate gyrus; Hippocampus; Hypothyroid; Hypothyroxinemia; In vivo; Learning; Long term potentiation; LTP

Indexed keywords

DRINKING WATER; LIOTHYRONINE; PROPYLTHIOURACIL; THYROID HORMONE; THYROTROPIN; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSOCIATION; BRAIN DEVELOPMENT; BRAIN FUNCTION; BRAIN TOXICITY; CONDITIONING; CONTROLLED STUDY; DENTATE GYRUS; DOSE RESPONSE; ELECTRIC POTENTIAL; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; FEAR; FEMALE; HYPOTHYROIDISM; INHIBITORY POSTSYNAPTIC POTENTIAL; LEARNING; LIOTHYRONINE BLOOD LEVEL; LONG TERM POTENTIATION; MALE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEWBORN; NONHUMAN; PAIRED ASSOCIATE LEARNING; PAIRED PULSE DEPRESSION; PAIRED PULSE FACILITATION; PERINATAL PERIOD; RAT; SHOCK; SPIKE WAVE; SYNAPSE; SYNAPTIC TRANSMISSION; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; WEANING;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTITHYROID AGENTS; BEHAVIOR, ANIMAL; BRAIN; CONDITIONING, CLASSICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; FEAR; FEMALE; INHIBITORY POSTSYNAPTIC POTENTIALS; LONG-TERM POTENTIATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROPYLTHIOURACIL; RATS; RATS, LONG-EVANS; THYROID HORMONES;

EID: 81855168334     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr244     Document Type: Article

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