The maternal HLA-G 1597ΔC null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women

Molecular Human Reproduction

Volumn 19, Issue 3, 2013, Pages 144-152

  Loisel, Dagan A ^a,d   Billstrand, Christine ^a   Murray, Kathleen ^a   Patterson, Kristen ^a   Chaiworapongsa, Tinnakorn ^b,c   Romero, Roberto ^c   Ober, Carole ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d SAINT MICHAEL'S COLLEGE   (United States)

Author keywords

DNA variants; Genetic predisposition; Mutation; Soluble HLA G; Toxemia of pregnancy

Indexed keywords

HLA G ANTIGEN;

ADULT; AFRICAN AMERICAN; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE SEVERITY; FEMALE; GENE FREQUENCY; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; NULL ALLELE; PREECLAMPSIA; PREGNANCY; PREMATURITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SYSTOLIC BLOOD PRESSURE;

ADULT; AFRICAN AMERICANS; ALLELES; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HLA-G ANTIGENS; HUMANS; INFANT, NEWBORN; POLYMORPHISM, GENETIC; PRE-ECLAMPSIA; PREGNANCY; RISK; SEVERITY OF ILLNESS INDEX;

EID: 84876462578     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gas041     Document Type: Article

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