A null mutation in HLA-G is not associated with preeclampsia or intrauterine growth retardation

Journal of Reproductive Immunology

Volumn 47, Issue 1, 2000, Pages 41-48

  Aldrich, Carrie ^a   Verp, Marion S ^a   Walker, Mary Ann ^a   Ober, Carole ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

HLA G; IUGR; Placenta; Preeclampsia; Trophoblast

Indexed keywords

HLA G ANTIGEN;

ARTICLE; CONTROLLED STUDY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; INFANT; INTRAUTERINE GROWTH RETARDATION; MAJOR CLINICAL STUDY; MUTATION; PLACENTA; PREECLAMPSIA; PRIORITY JOURNAL; TROPHOBLAST;

ADOLESCENT; ADULT; ALLELES; FEMALE; FETAL GROWTH RETARDATION; GENE FREQUENCY; GENES, MHC CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; INFANT, NEWBORN; PRE-ECLAMPSIA; PREGNANCY; SEQUENCE DELETION;

EID: 0034076917     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(00)00052-8     Document Type: Article

References (30)

1. Bell G.I., Karam J.H., Rutter W.J. Polymorphic DNA region adjacent to the 5′ end of the human insulin gene. Proc. Natl. Acad. Sci. USA. 78:1981;5759-5763.
2. Bensussan A., Mansur I.G., Mallet V., Rodriguez A.M., Girr M., Weiss E., Brem B., Boumsell L., Gluckman E., Dausset J., Carosella E., Le Bouteiller P. Detection of membrane-bound HLA-G translated products with a specific monoclonal antibody. Proc. Natl. Acad. Sci. USA. 92:1995;10292-10296.
3. Berg C.J., Atrash H.K., Koonin L.M., Tucker M. Pregnancy-related mortality in the United States, 1987-1990. Obstet. Gynecol. 88:1996;161-167.
4. Bernstein P.S., Divon M.Y. Etiologies of fetal growth restriction. Clin. Obstet. Gynecol. 40:1997;723-729.
5. Chu W., Fant M.E., Geraghty D.E., Hunt J.S. Soluble HLA-G in human placentas: synthesis in trophoblasts and interferon-gamma-activated macrophages but not placental fibroblasts. Hum. Immunol. 59:1998;435-442.
6. Chumbley G., King A., Gardner L., Howlett S., Holmes N., Loke Y.M. Generation of an antibody to HLA-G in transgenic mice and demonstration of the tissue reactivity of this antibody. J. Reprod. Immunol. 27:1994;173-186.
7. Colbern G.T., Chiang M.H., Main E.K. Expression of the nonclassic histocompatibility antigen HLA-G by preeclamptic placenta. Am. J. Obstet. Gynecol. 170:1994;1244-1250.
8. A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat. Genet. 15(4):1997;389-392.
9. Cunningham F.G. Cunningham F.G. Williams Obstetrics. 1997;694 Appleton & Lange, Stamford, CT.
10. Hammer A., Hutter H., Blaschitz A., Mahnert W., Hartman M., Uchanska-Ziegler B., Zieglar A., Dohr G. Amnion epithelial cells, in contrast to trophoblast cells, express all classical HLA class I molecules together with HLA-G. Am. J. Reprod. Immunol. 37:1997;161-171.
11. Hara N., Fujii T., Yamashita T., Kozuma S., Onai T., Taketani Y. Altered expression of human leukocyte antigen G (HLA-G) on extravillous trophoblasts in preeclampsia: immunohistological demonstration with anti-HLA-G specific antibody '87G' and anti-cytokeratin antibody 'CAM5.2'. Am. J. Reprod. Immunol. 36:1996;349-358.
12. Hunt J.S., Orr H.T. HLA and maternal-fetal recognition. Faseb. J. 6:1992;2344-2348.
13. Hutter H., Hammer A., Blaschitz A., Hartmann M., Ebbesen P., Dohr F., Ziegler A., Uchanska-Ziegler B. Expression of HLA class I molecules in human first trimester and term placenta trophoblast [published erratum appears in Cell Tissue Res. 1997 Mar; 287(3):625]. Cell Tissue Res. 286:1996;439-447.
14. Hutter H., Hammer A., Dohr G., Hunt J.S. HLA expression at the maternal-fetal interface. Dev. Immunol. 6:1998;197-204.
15. Jacob S., Bloebaum L., Shah G., Varner M.W. Maternal mortality in Utah. Obstet. Gynecol. 91:1998;187-191.
16. Khong T.Y., Lane E.B., Robertson W.B. An immunocytochemical study of fetal cells at the maternal-placental interface using monoclonal antibodies to keratins, vimentin and desmin. Cell Tissue Res. 246:1986;189-195.
17. Le Bouteiller P., Mallet V. HLA-G and pregnancy. Rev. Reprod. 2:1997;7-13.
18. Le Bouteiller P., Solier C., Proll J., Aguerre-Girr M., Fournel S., Lenfent F.H. Placental HLA-G protein expression in vivo: where and what for? Hum. Reprod. Update. 5:1999;223-233.
19. Lim K.H., Zhou Y., Janatpour M., McMaster M., Bass K., Chun S.H., Fisher S.J. Human cytotrophoblast differentiation/invasion is abnormal in pre-eclampsia. Am. J. Pathol. 151:1997;1809-1818.
20. Loke Y.W., King A., Burrows T., Gardner L., Bowen M., Hibby S., Howlett S., Holmer N., Jacobs D. Evaluation of trophoblast HLA-G antigen with a specific monoclonal antibody. Tissue Antigens. 50:1997;135-146.
21. McMaster M., Zhou Y., Shorter S., Kapasi K., Geroghty D., Lim K.H., Fisher S. HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation. J. Immunol. 160:1998;5922-5928.
22. McMaster M.T., Librach C.L., Zhou Y., Lim K.H., Janatpour M.J., De Mars R., Kovats S., Damsky C., Fisher S.J. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J. Immunol. 154:1995;3771-3778.
23. Morales P., Corell A., Martinez-Laso J., Martin-Villa J.M., Vatela P., Paz-Artal E., Allende L.M., Arnaiz-Villena A. Three new HLA-G alleles and their linkage disequilibria with HLA-A. Immunogenetics. 38:1993;323-331.
24. Ober C., Aldrich C., Rosinsky B., Robertson A., Walker M.A., Willadsen S., Verp M.S., Geraghty D.F., Hunt J.S. HLA-G1 protein expression is not essential for fetal survival. Placenta. 19:1998;127-132.
25. Ober C., Aldrich C.L. HLA-G polymorphisms: neutral evolution or novel function? J. Reprod. Immunol. 36:1997;1-21.
26. Ober C., Xiang K.S., Thisted R.A., Indovina K.A., Wason G.J., Dooley S. Increased risk for gestational diabetes mellitus associated with insulin receptor and insulin-like growth factor II restriction fragment length polymorphisms. Genet. Epidemiol. 6:1989;559-569.
27. Salafia C.M. Placental pathology of fetal growth restriction. Clin. Obstet. Gynecol. 40:1997;740-749.
28. Sibai B.M. Hypertension in Pregnancy. Gabbe S.G., Niebyl J.R., Simpson J.L. Obstetrics: Normal and Problem Pregnancies. 1996;Churchill Livingstone Inc, Philadelphia, PA.
29. Suarez M.B., Morales P., Castro M.J., Fernandez V., Varela P., Alvarez M., Martinez-Laso J., Arnaiz-Villena A. A new HLA-G allele (HLA-G*0105N) and its distribution in the Spanish population. Immunogenetics. 45:1997;464-465.
30. Verp M.S., Sibul M., Billstrand C., Bellen G., Hsu M., Ober L. Maternal-fetal histocompatibility in intrauterine growth retarded and normal weight babies. Am. J. Reprod. Immunol. 29:1993;195-198.