-
1
-
-
0025952455
-
Recent advances in the phencyclidine model of schizophrenia
-
Javitt DC, Zukin SR, (1991) Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 148: 1301-1308.
-
(1991)
Am J Psychiatry
, vol.148
, pp. 1301-1308
-
-
Javitt, D.C.1
Zukin, S.R.2
-
2
-
-
0033190699
-
NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders
-
Krystal JH, D'Souza DC, Petrakis IL, Belger A, Berman RM, et al. (1999) NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders. Harv Rev Psychiatry 7: 125-143.
-
(1999)
Harv Rev Psychiatry
, vol.7
, pp. 125-143
-
-
Krystal, J.H.1
D'Souza, D.C.2
Petrakis, I.L.3
Belger, A.4
Berman, R.M.5
-
3
-
-
3142737856
-
The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia
-
Coyle JT, Tsai G, (2004) The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia. Psychopharmacology (Berl) 174: 32-38.
-
(2004)
Psychopharmacology (Berl)
, vol.174
, pp. 32-38
-
-
Coyle, J.T.1
Tsai, G.2
-
4
-
-
0346277091
-
Decoding schizophrenia
-
Javitt DC, Coyle JT, (2004) Decoding schizophrenia. Sci Am 290: 48-55.
-
(2004)
Sci Am
, vol.290
, pp. 48-55
-
-
Javitt, D.C.1
Coyle, J.T.2
-
5
-
-
21244442890
-
Dysfunction of glia-neuron communication in pathophysiology of schizophrenia
-
Hashimoto K, Shimizu E, Iyo M, (2005) Dysfunction of glia-neuron communication in pathophysiology of schizophrenia. Curr Psychiatry Rev 1: 151-163.
-
(2005)
Curr Psychiatry Rev
, vol.1
, pp. 151-163
-
-
Hashimoto, K.1
Shimizu, E.2
Iyo, M.3
-
6
-
-
33748455912
-
The NMDA receptor hypofunction hypothesis for schizophrenia and glycine modulatory sites on the NMDA receptors as potential therapeutic drugs
-
Hashimoto K, (2006) The NMDA receptor hypofunction hypothesis for schizophrenia and glycine modulatory sites on the NMDA receptors as potential therapeutic drugs. Clin Psychopharmacol Neurosci 4: 3-10.
-
(2006)
Clin Psychopharmacol Neurosci
, vol.4
, pp. 3-10
-
-
Hashimoto, K.1
-
7
-
-
0033582230
-
Purification of serine racemase: biosynthesis of the neuromodulator D-serine
-
Wolosker H, Sheth KN, Takahashi M, Mothet JP, Brady RO Jr, et al. (1999) Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proc Natl Acad Sci USA 96: 721-725.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 721-725
-
-
Wolosker, H.1
Sheth, K.N.2
Takahashi, M.3
Mothet, J.P.4
Brady Jr., R.O.5
-
8
-
-
0033539510
-
Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission
-
Wolosker H, Blackshaw S, Snyder SH, (1999) Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proc Natl Acad Sci USA 96: 13409-13414.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13409-13414
-
-
Wolosker, H.1
Blackshaw, S.2
Snyder, S.H.3
-
9
-
-
84868097320
-
Serine racemase: an unconventional enzyme for an unconventional transmitter
-
Wolosker H, Mori H, (2012) Serine racemase: an unconventional enzyme for an unconventional transmitter. Amino Acids 43: 1895-1904.
-
(2012)
Amino Acids
, vol.43
, pp. 1895-1904
-
-
Wolosker, H.1
Mori, H.2
-
10
-
-
58149373550
-
NMDA- and β-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice
-
Inoue R, Hashimoto K, Harai T, Mori H, (2008) NMDA- and β-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice. J Neurosci 28: 14486-14491.
-
(2008)
J Neurosci
, vol.28
, pp. 14486-14491
-
-
Inoue, R.1
Hashimoto, K.2
Harai, T.3
Mori, H.4
-
11
-
-
67649329655
-
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior
-
Basu AC, Tsai GE, Ma CL, Ehmsen JT, Mustafa AK, et al. (2009) Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior. Mol Psychiatry 14: 719-727.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 719-727
-
-
Basu, A.C.1
Tsai, G.E.2
Ma, C.L.3
Ehmsen, J.T.4
Mustafa, A.K.5
-
12
-
-
80053347695
-
Levels of D-serine in the brain and peripheral organs of serine racemase (Srr) knock-out mice
-
Horio M, Kohno M, Fujita Y, Ishima T, Inoue R, et al. (2011) Levels of D-serine in the brain and peripheral organs of serine racemase (Srr) knock-out mice. Neurochem Int 59: 853-859.
-
(2011)
Neurochem Int
, vol.59
, pp. 853-859
-
-
Horio, M.1
Kohno, M.2
Fujita, Y.3
Ishima, T.4
Inoue, R.5
-
13
-
-
84878407346
-
Is D-cycloserine a pro-drug for D-serine in the brain?
-
Aug 7. [Epub ahead of print]
-
Horio M, Mori H, Hashimoto K (in press) Is D-cycloserine a pro-drug for D-serine in the brain? Biol Psychiatry 2012 Aug 7. [Epub ahead of print].
-
(2012)
Biol Psychiatry
-
-
Horio, M.1
Mori, H.2
Hashimoto, K.3
-
14
-
-
0027473657
-
Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging
-
Hashimoto A, Nishikawa T, Oka T, Takahashi K, (1993) Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging. J Neurochem 60: 783-786.
-
(1993)
J Neurochem
, vol.60
, pp. 783-786
-
-
Hashimoto, A.1
Nishikawa, T.2
Oka, T.3
Takahashi, K.4
-
15
-
-
0031046980
-
D-Serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptor
-
Schell MJ, Brady RO Jr, Molliver ME, Snyder SH, (1997) D-Serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptor. J Neurosci 17: 1604-1615.
-
(1997)
J Neurosci
, vol.17
, pp. 1604-1615
-
-
Schell, M.J.1
Brady Jr., R.O.2
Molliver, M.E.3
Snyder, S.H.4
-
16
-
-
0141891918
-
Spatiotemporal relationships among D-serine, serine racemase, and D-amino acid oxidase during mouse postnatal development
-
Wang LZ, Zhu XZ, (2003) Spatiotemporal relationships among D-serine, serine racemase, and D-amino acid oxidase during mouse postnatal development. Acta Pharmacol Sci 24: 965-974.
-
(2003)
Acta Pharmacol Sci
, vol.24
, pp. 965-974
-
-
Wang, L.Z.1
Zhu, X.Z.2
-
17
-
-
79953315208
-
Recent advances in the discovery of D-amino acid oxidase inhibitors and their therapeutic utility in schizophrenia
-
Ferraris DV, Tsukamoto T, (2011) Recent advances in the discovery of D-amino acid oxidase inhibitors and their therapeutic utility in schizophrenia. Curr Pharm Des 17: 103-111.
-
(2011)
Curr Pharm Des
, vol.17
, pp. 103-111
-
-
Ferraris, D.V.1
Tsukamoto, T.2
-
18
-
-
84856089057
-
Contributions of the D-serine pathway to schizophrenia
-
Labrie V, Wong AH, Roder JC, (2012) Contributions of the D-serine pathway to schizophrenia. Neuropharmacology 62: 1484-1503.
-
(2012)
Neuropharmacology
, vol.62
, pp. 1484-1503
-
-
Labrie, V.1
Wong, A.H.2
Roder, J.C.3
-
19
-
-
84866674097
-
Has an angel shown the way? Etiological and therapeutic implications of the PCP/NMDA model of schizophrenia
-
Javitt DC, Zukin SR, Heresco-Levy U, Umbricht D, (2012) Has an angel shown the way? Etiological and therapeutic implications of the PCP/NMDA model of schizophrenia. Schizophr Bull 38: 958-966.
-
(2012)
Schizophr Bull
, vol.38
, pp. 958-966
-
-
Javitt, D.C.1
Zukin, S.R.2
Heresco-Levy, U.3
Umbricht, D.4
-
20
-
-
0037977113
-
Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia
-
Hashimoto K, Fukushima T, Shimizu E, Komatsu N, Watanabe H, et al. (2003) Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry 60: 572-576.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 572-576
-
-
Hashimoto, K.1
Fukushima, T.2
Shimizu, E.3
Komatsu, N.4
Watanabe, H.5
-
21
-
-
20444406392
-
Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels
-
Yamada K, Ohnishi T, Hashimoto K, Ohba H, Iwayama-Shigeno Y, et al. (2005) Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels. Biol Psychiatry 57: 1493-1503.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 1493-1503
-
-
Yamada, K.1
Ohnishi, T.2
Hashimoto, K.3
Ohba, H.4
Iwayama-Shigeno, Y.5
-
22
-
-
21244502642
-
Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients
-
Hashimoto K, Engberg G, Shimizu E, Nordin C, Lindström LH, et al. (2005) Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry 29: 767-769.
-
(2005)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.29
, pp. 767-769
-
-
Hashimoto, K.1
Engberg, G.2
Shimizu, E.3
Nordin, C.4
Lindström, L.H.5
-
23
-
-
33846640657
-
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia
-
Bendikov I, Nadri C, Amar S, Panizzutti R, De Miranda J, et al. (2007) A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophr Res 90: 41-51.
-
(2007)
Schizophr Res
, vol.90
, pp. 41-51
-
-
Bendikov, I.1
Nadri, C.2
Amar, S.3
Panizzutti, R.4
De Miranda, J.5
-
24
-
-
84869880210
-
Plasma levels of D-serine in Brazillian individuals with schizophrenia
-
Calcia MA, Madeira C, Alheira FV, Silva TC, Tannos FM, et al. (2012) Plasma levels of D-serine in Brazillian individuals with schizophrenia. Schizophr Res 142: 93-87.
-
(2012)
Schizophr Res
, vol.142
, pp. 87-93
-
-
Calcia, M.A.1
Madeira, C.2
Alheira, F.V.3
Silva, T.C.4
Tannos, F.M.5
-
25
-
-
0032403626
-
D-serine added to antipsychotics for the treatment of schizophrenia
-
Tsai G, Yang P, Chung LC, Lange L, Coyle JT, (1998) D-serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry 44: 1081-1089.
-
(1998)
Biol Psychiatry
, vol.44
, pp. 1081-1089
-
-
Tsai, G.1
Yang, P.2
Chung, L.C.3
Lange, L.4
Coyle, J.T.5
-
26
-
-
15444377601
-
D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia
-
Heresco-Levy U, Javitt DC, Ebstein R, Vass A, Lichtenberg P, et al. (2005) D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia. Biol Psychiatry 57: 577-585.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 577-585
-
-
Heresco-Levy, U.1
Javitt, D.C.2
Ebstein, R.3
Vass, A.4
Lichtenberg, P.5
-
27
-
-
77949447469
-
Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia. A critical review and meta-analysis
-
Tsai GE, Lin PY, (2010) Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia. A critical review and meta-analysis. Curr Pham Des 16: 522-537.
-
(2010)
Curr Pham Des
, vol.16
, pp. 522-537
-
-
Tsai, G.E.1
Lin, P.Y.2
-
28
-
-
34548689595
-
D-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia
-
Verrall L, Walker A, Rawlings N, Benzel I, Kew JNC, et al. (2007) D-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia. Eur J Neurosci 26: 1657-1669.
-
(2007)
Eur J Neurosci
, vol.26
, pp. 1657-1669
-
-
Verrall, L.1
Walker, A.2
Rawlings, N.3
Benzel, I.4
Kew, J.N.C.5
-
29
-
-
43049108742
-
Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia
-
Madeira C, Freitas ME, Vargas-Lopes C, Wolosker H, Panizzutti R, (2008) Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia. Schizophr Res 101: 76-83.
-
(2008)
Schizophr Res
, vol.101
, pp. 76-83
-
-
Madeira, C.1
Freitas, M.E.2
Vargas-Lopes, C.3
Wolosker, H.4
Panizzutti, R.5
-
30
-
-
0037108758
-
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia
-
Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, et al. (2002) Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc Natl Acad Sci USA 99: 13675-13680.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13675-13680
-
-
Chumakov, I.1
Blumenfeld, M.2
Guerassimenko, O.3
Cavarec, L.4
Palicio, M.5
-
31
-
-
45549098188
-
Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function
-
Kvajo M, Dhilla A, Swor DE, Karayiorgou M, Gogos JA, (2008) Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function. Mol Psychiatry 13: 685-696.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 685-696
-
-
Kvajo, M.1
Dhilla, A.2
Swor, D.E.3
Karayiorgou, M.4
Gogos, J.A.5
-
32
-
-
33745689721
-
G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis
-
Detetra-Wadleigh SD, McMahon FJ, (2006) G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis. Biol Psychiatry 60: 106-114.
-
(2006)
Biol Psychiatry
, vol.60
, pp. 106-114
-
-
Detetra-Wadleigh, S.D.1
McMahon, F.J.2
-
33
-
-
0023215296
-
Implications of normal brain development for the pathogenesis of schizophrenia
-
Weinberger DR, (1987) Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 44: 660-669.
-
(1987)
Arch Gen Psychiatry
, vol.44
, pp. 660-669
-
-
Weinberger, D.R.1
-
34
-
-
0029684862
-
Neurodevelopmental abnormalities and schizophrenia. A family affair
-
Wyatt RJ, (1996) Neurodevelopmental abnormalities and schizophrenia. A family affair. Arch Gen Psychiatry 53: 11-15.
-
(1996)
Arch Gen Psychiatry
, vol.53
, pp. 11-15
-
-
Wyatt, R.J.1
-
35
-
-
0038779583
-
The neurodevelopmental hypothesis of schizophrenia: a review of recent developments
-
McGrath JJ, Féron FP, Burne TH, Mackay-Sim A, Eyles DW, (2003) The neurodevelopmental hypothesis of schizophrenia: a review of recent developments. Ann Med 35: 86-93.
-
(2003)
Ann Med
, vol.35
, pp. 86-93
-
-
McGrath, J.J.1
Féron, F.P.2
Burne, T.H.3
Mackay-Sim, A.4
Eyles, D.W.5
-
36
-
-
13844306349
-
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration
-
Kim PM, Aizawa H, Kim PS, Huang AS, Wickramasinghe SR, et al. (2005) Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration. Proc Natl Acad Sci USA 102: 2105-2110.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2105-2110
-
-
Kim, P.M.1
Aizawa, H.2
Kim, P.S.3
Huang, A.S.4
Wickramasinghe, S.R.5
-
37
-
-
11844253187
-
Simultaneous determination of D- and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection
-
Fukushima T, Kawai J, Imai K, Toyo'oka T, (2004) Simultaneous determination of D- and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection. Biomed Chromatogr 18: 813-819.
-
(2004)
Biomed Chromatogr
, vol.18
, pp. 813-819
-
-
Fukushima, T.1
Kawai, J.2
Imai, K.3
Toyo'oka, T.4
-
38
-
-
26844558198
-
Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients
-
Hashimoto K, Engberg G, Shimizu E, Nordin C, Lindstrom LH, et al. (2005) Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients. BMC Psychiatry 5: 6.
-
(2005)
BMC Psychiatry
, vol.5
, pp. 6
-
-
Hashimoto, K.1
Engberg, G.2
Shimizu, E.3
Nordin, C.4
Lindstrom, L.H.5
-
39
-
-
35848939420
-
Increased levels of glutamate in brains from patients with mood disorders
-
Hashimoto K, Sawa A, Iyo M, (2007) Increased levels of glutamate in brains from patients with mood disorders. Biol. Psychiatry 62: 1310-1316.
-
(2007)
Biol. Psychiatry
, vol.62
, pp. 1310-1316
-
-
Hashimoto, K.1
Sawa, A.2
Iyo, M.3
-
40
-
-
33644610741
-
Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of schizophrenia
-
Ozawa K, Hashimoto K, Kishimoto T, Shimizu E, Ishikura H, et al. (2006) Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of schizophrenia. Biol Psychiatry 59: 546-554.
-
(2006)
Biol Psychiatry
, vol.59
, pp. 546-554
-
-
Ozawa, K.1
Hashimoto, K.2
Kishimoto, T.3
Shimizu, E.4
Ishikura, H.5
-
41
-
-
34547884686
-
Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine
-
Zhang L, Shirayama Y, Iyo M, Hashimoto K, (2007) Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine. Neuropsychopharmacology 32: 2004-2010.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 2004-2010
-
-
Zhang, L.1
Shirayama, Y.2
Iyo, M.3
Hashimoto, K.4
-
42
-
-
71849091116
-
Mithramycin protects dopaminergic neurotoxicity in mouse brain after administration of methamphetamine
-
Hagiwara H, Iyo M, Hashimoto K, (2009) Mithramycin protects dopaminergic neurotoxicity in mouse brain after administration of methamphetamine. Brain Res 1301: 189-196.
-
(2009)
Brain Res
, vol.1301
, pp. 189-196
-
-
Hagiwara, H.1
Iyo, M.2
Hashimoto, K.3
-
43
-
-
27744572308
-
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol
-
Hashimoto K, Fujita Y, Shimizu E, Iyo M, (2005) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol. Eur J Pharmacol 519: 114-117.
-
(2005)
Eur J Pharmacol
, vol.519
, pp. 114-117
-
-
Hashimoto, K.1
Fujita, Y.2
Shimizu, E.3
Iyo, M.4
-
44
-
-
33847044420
-
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: Role of sigma-1 receptors
-
Hashimoto K, Fujita Y, Iyo M, (2007) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: Role of sigma-1 receptors. Neuropsychopharmacology 32: 514-521.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 514-521
-
-
Hashimoto, K.1
Fujita, Y.2
Iyo, M.3
-
45
-
-
36849055179
-
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective α7 nicotinic receptor agonist SSR180711
-
Hashimoto K, Ishima T, Fujita Y, Matsuo M, Kobashi T, et al. (2008) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective α7 nicotinic receptor agonist SSR180711. Biol Psychiatry 63: 92-97.
-
(2008)
Biol Psychiatry
, vol.63
, pp. 92-97
-
-
Hashimoto, K.1
Ishima, T.2
Fujita, Y.3
Matsuo, M.4
Kobashi, T.5
-
46
-
-
67349116852
-
Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine
-
Hashimoto K, Fujita Y, Horio M, Kunitachi S, Iyo M, et al. (2009) Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine. Biol Psychiatry 65: 1103-1106.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 1103-1106
-
-
Hashimoto, K.1
Fujita, Y.2
Horio, M.3
Kunitachi, S.4
Iyo, M.5
-
47
-
-
0031800004
-
Effects of continuous D-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats
-
Sams-Dodd F, (1998) Effects of continuous D-amphetamine and phencyclidine administration on social behaviour, stereotyped behaviour, and locomotor activity in rats. Neuropsychopharmacology 19: 18-25.
-
(1998)
Neuropsychopharmacology
, vol.19
, pp. 18-25
-
-
Sams-Dodd, F.1
-
48
-
-
1442299144
-
Repeated administration of phencyclidine, amphetamine and MK-801 selectively impairs spatial learning in mice: a possible model of psychotomimetic drug-induced cognitive deficits
-
Mandillo S, Rinaldi A, Oliverio A, Mele A, (2003) Repeated administration of phencyclidine, amphetamine and MK-801 selectively impairs spatial learning in mice: a possible model of psychotomimetic drug-induced cognitive deficits. Behav Pharmacol 14: 533-544.
-
(2003)
Behav Pharmacol
, vol.14
, pp. 533-544
-
-
Mandillo, S.1
Rinaldi, A.2
Oliverio, A.3
Mele, A.4
-
49
-
-
0032498608
-
Neuropsychological correlates of positive vs. negative schizophrenic symptomatology
-
Zakzanis KK, (1998) Neuropsychological correlates of positive vs. negative schizophrenic symptomatology. Schizophr Res 29: 227-233.
-
(1998)
Schizophr Res
, vol.29
, pp. 227-233
-
-
Zakzanis, K.K.1
-
50
-
-
27744572308
-
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol
-
Hashimoto K, Fujita Y, Shimizu E, Iyo M, (2005) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol. Eur J Pharmacol 519: 114-117.
-
(2005)
Eur J Pharmacol
, vol.519
, pp. 114-117
-
-
Hashimoto, K.1
Fujita, Y.2
Shimizu, E.3
Iyo, M.4
-
51
-
-
42749085595
-
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of glycine transporter-1 inhibitor NFPS and D-serine
-
Hashimoto K, Fujita Y, Ishima T, Chaki S, Iyo M, (2008) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of glycine transporter-1 inhibitor NFPS and D-serine. Eur Neuropsychopharmacol 18: 414-421.
-
(2008)
Eur Neuropsychopharmacol
, vol.18
, pp. 414-421
-
-
Hashimoto, K.1
Fujita, Y.2
Ishima, T.3
Chaki, S.4
Iyo, M.5
-
52
-
-
0025190458
-
Sensorimotor gating and schizophrenia. Human and animal model studies
-
Braff DL, Geyer MA, (1990) Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatry 47: 181-188.
-
(1990)
Arch Gen Psychiatry
, vol.47
, pp. 181-188
-
-
Braff, D.L.1
Geyer, M.A.2
-
53
-
-
0035666578
-
The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches
-
Lieberman JA, Perkins D, Belger A, Chakos M, Jarskog F, et al. (2001) The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches. Biol Psychiatry 50: 884-897.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 884-897
-
-
Lieberman, J.A.1
Perkins, D.2
Belger, A.3
Chakos, M.4
Jarskog, F.5
-
54
-
-
1642323732
-
Nonspecific and attenuated negative symptoms in patients at clinical high-risk for schizophrenia
-
Lencz T, Smith CW, Auther A, Correll CU, Cornblatt B, (2004) Nonspecific and attenuated negative symptoms in patients at clinical high-risk for schizophrenia. Schizophr Res 68: 37-48.
-
(2004)
Schizophr Res
, vol.68
, pp. 37-48
-
-
Lencz, T.1
Smith, C.W.2
Auther, A.3
Correll, C.U.4
Cornblatt, B.5
-
55
-
-
80052476997
-
Impact of neurocognition on social and role functioning in individuals at clinical high risk for psychosis
-
Carrión RE, Goldberg TE, McLaughlin D, Auther AM, Correll CU, et al. (2011) Impact of neurocognition on social and role functioning in individuals at clinical high risk for psychosis. Am J Psychiatry 168: 806-813.
-
(2011)
Am J Psychiatry
, vol.168
, pp. 806-813
-
-
Carrión, R.E.1
Goldberg, T.E.2
McLaughlin, D.3
Auther, A.M.4
Correll, C.U.5
-
56
-
-
70350441313
-
Intervention in individuals at ultra-high risk for psychosis: a review and future directions
-
McGorry PD, Nelson B, Amminger GP, Bechdolf A, Francey SM, et al. (2009) Intervention in individuals at ultra-high risk for psychosis: a review and future directions. J Clin Psychiatry 70: 1206-1212.
-
(2009)
J Clin Psychiatry
, vol.70
, pp. 1206-1212
-
-
McGorry, P.D.1
Nelson, B.2
Amminger, G.P.3
Bechdolf, A.4
Francey, S.M.5
-
57
-
-
84862017225
-
Cognitive functioning in prodromal psychosis: a meta-analysis
-
Fusar-Poli P, Deste G, Smieskova R, Barlati S, Yung AR, et al. (2012) Cognitive functioning in prodromal psychosis: a meta-analysis. Arch Gen Psychiatry 69: 562-571.
-
(2012)
Arch Gen Psychiatry
, vol.69
, pp. 562-571
-
-
Fusar-Poli, P.1
Deste, G.2
Smieskova, R.3
Barlati, S.4
Yung, A.R.5
-
58
-
-
79959571366
-
Preventive pharmacological treatment - An evolving new concept in schizophrenia
-
Sabbag R, Levin R, Edelman S, Heresco-Levy U, (2011) Preventive pharmacological treatment - An evolving new concept in schizophrenia. Isr J Psychiatry Relat Sci 48: 82-90.
-
(2011)
Isr J Psychiatry Relat Sci
, vol.48
, pp. 82-90
-
-
Sabbag, R.1
Levin, R.2
Edelman, S.3
Heresco-Levy, U.4
-
59
-
-
84881665236
-
Glycine treatment of the risk syndrome for psychosis: Report of two pilots studies
-
Oct 19. doi:pii: S0924-977X(12)00272-6. 10.1016/j.euroneuro.2012.09.008. [Epub ahead of print]
-
Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR,et al. (in press) Glycine treatment of the risk syndrome for psychosis: Report of two pilots studies. Eur Neuropsychopharmacol 2012 Oct 19. doi:pii: S0924-977X(12)00272-6. 10.1016/j.euroneuro.2012.09.008. [Epub ahead of print].
-
(2012)
Eur Neuropsychopharmacol
-
-
Woods, S.W.1
Walsh, B.C.2
Hawkins, K.A.3
Miller, T.J.4
Saksa, J.R.5
-
60
-
-
77955056793
-
High dose of D-serine in the treatment of schizophrenia
-
Kantrowitz JT, Malhotra AK, Cornblatt B, Silipo G, Balla A, et al. (2010) High dose of D-serine in the treatment of schizophrenia. Schizophr Res 121: 125-130.
-
(2010)
Schizophr Res
, vol.121
, pp. 125-130
-
-
Kantrowitz, J.T.1
Malhotra, A.K.2
Cornblatt, B.3
Silipo, G.4
Balla, A.5
-
61
-
-
70349513258
-
Emerging role of glutamate in the pathophysiology of major depressive disorder
-
Hashimoto K, (2009) Emerging role of glutamate in the pathophysiology of major depressive disorder. Brain Res Rev 61: 105-123.
-
(2009)
Brain Res Rev
, vol.61
, pp. 105-123
-
-
Hashimoto, K.1
-
62
-
-
78649990339
-
Analyses of mechanism for mouse strain-dependent prepulse inhibition point to a role of Shmt1 (SHMT1) in mice and schizophrenia
-
Maekawa T, Ohnishi T, Hashimoto K, Watanabe A, Iwayama Y, et al. (2010) Analyses of mechanism for mouse strain-dependent prepulse inhibition point to a role of Shmt1 (SHMT1) in mice and schizophrenia. J Neurochem 115: 1374-1385.
-
(2010)
J Neurochem
, vol.115
, pp. 1374-1385
-
-
Maekawa, T.1
Ohnishi, T.2
Hashimoto, K.3
Watanabe, A.4
Iwayama, Y.5
-
63
-
-
84881313914
-
Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders
-
Mar 1. [Epub ahead of print]
-
Hashimoto K, Malchow B, Falkai P, Schmitt P (in press) Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders. Eur Arch Psychiatry Clin Neurosci 2013 Mar 1. [Epub ahead of print].
-
(2013)
Eur Arch Psychiatry Clin Neurosci
-
-
Hashimoto, K.1
Malchow, B.2
Falkai, P.3
Schmitt, P.4
-
64
-
-
0025837148
-
Redox modulatory site of the NMDA receptor-channel complex: Regulation by oxidized glutathione
-
Sucher NJ, Lipton SA, (1991) Redox modulatory site of the NMDA receptor-channel complex: Regulation by oxidized glutathione. J Neurosci Res 30: 582-591.
-
(1991)
J Neurosci Res
, vol.30
, pp. 582-591
-
-
Sucher, N.J.1
Lipton, S.A.2
-
65
-
-
0028339034
-
NMDA receptor channels: Subunit-specific potentiation by reducing agents
-
Kohr G, Eckardt S, Luddens H, Monyer H, Seeburg PH, (1994) NMDA receptor channels: Subunit-specific potentiation by reducing agents. Neuron 12: 1031-1040.
-
(1994)
Neuron
, vol.12
, pp. 1031-1040
-
-
Kohr, G.1
Eckardt, S.2
Luddens, H.3
Monyer, H.4
Seeburg, P.H.5
-
66
-
-
0030876671
-
Glutathione is an endogenous ligand of rat brain N-methyl-D-aspartate (NMDA) and 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors
-
Varga V, Jenei Z, Janaky R, Saransaari P, Oja SS, (1997) Glutathione is an endogenous ligand of rat brain N-methyl-D-aspartate (NMDA) and 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors. Neurochem Res 22: 1165-1171.
-
(1997)
Neurochem Res
, vol.22
, pp. 1165-1171
-
-
Varga, V.1
Jenei, Z.2
Janaky, R.3
Saransaari, P.4
Oja, S.S.5
-
67
-
-
44849102210
-
Negative correlation between brain glutathione levels and negative symptoms in schizophrenia: a 3T 1H-MRS study
-
Matsuzawa D, Obata T, Shirayama Y, Nonaka H, Kanazawa Y, et al. (2008) Negative correlation between brain glutathione levels and negative symptoms in schizophrenia: a 3T 1H-MRS study. PLoS ONE 3: e1944.
-
(2008)
PLoS ONE
, vol.3
-
-
Matsuzawa, D.1
Obata, T.2
Shirayama, Y.3
Nonaka, H.4
Kanazawa, Y.5
-
68
-
-
53249151600
-
Correspondence: Regarding "N-Acetyl cysteine as a glutathione precursor for schizophrenia - a double-blind, randomized, placebo-controlled trial"
-
Hashimoto K, (2008) Correspondence: Regarding "N-Acetyl cysteine as a glutathione precursor for schizophrenia - a double-blind, randomized, placebo-controlled trial". Biol Psychiatry 64: e1.
-
(2008)
Biol Psychiatry
, vol.64
-
-
Hashimoto, K.1
-
69
-
-
80051999965
-
Magnetic resonance spectroscopy study of antioxidant defense system in schizophrenia
-
Matsuzawa D, Hashimoto K, (2011) Magnetic resonance spectroscopy study of antioxidant defense system in schizophrenia. Antioxi Redox Sig15: 2057-2065.
-
(2011)
Antioxi Redox Sig
, vol.15
, pp. 2057-2065
-
-
Matsuzawa, D.1
Hashimoto, K.2
-
70
-
-
67650932879
-
Redox dysregulation, neurodevelopment, and schizophrenia
-
Do KQ, Cabungcal JH, Frank A, Steullet P, Cuenod M, (2009) Redox dysregulation, neurodevelopment, and schizophrenia. Curr Opin Neurobiol 19: 220-230.
-
(2009)
Curr Opin Neurobiol
, vol.19
, pp. 220-230
-
-
Do, K.Q.1
Cabungcal, J.H.2
Frank, A.3
Steullet, P.4
Cuenod, M.5
|