Glutathione is an endogenous ligand of rat brain N-methyl-D-aspartate (NMDA) and 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors

Neurochemical Research

Volumn 22, Issue 9, 1997, Pages 1165-1171

  Varga, V ^a,b   Jenaei, Zs ^a,b   Janaky R ^a   Saransaari, P ^a   Oja, S S ^a,c  

^a UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Endogenous regulator; Glutamate receptors; Reduced and oxidized glutathione

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 7 CHLOROKYNURENIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; DIZOCILPINE; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLYCINE; GLYCINE RECEPTOR ANTAGONIST; IONOPHORE; KAINIC ACID; LIGAND; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; FEMALE; LIGAND BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALS; CEREBRAL CORTEX; DIZOCILPINE MALEATE; FEMALE; GLUTATHIONE; GLUTATHIONE DISULFIDE; IONOPHORES; LIGANDS; MALE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE;

ANIMALIA;

EID: 0030876671     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1027377605054     Document Type: Article

References (4)

1. Rothman, S. M., and Olney, J. W. 1987. Excitotoxicity and the NMDA receptor. Trends Neurosci. 10:299-302.
2. Levy, D. I., Sucher, N. J., and Lipton S. A. 1991. Glutathione prevents N-methyl-D-aspartate receptor-mediated neurotoxicity. Neuroreport 2:345-347.
3. Seeburg, P. H. 1993. The TINS/TIPS lecture. The molecular biology of mammalian glutamate receptor channels. Trends Neurosci. 16:359-365.
4. Collingridge, G. L., and Lester, A. J. 1989. Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacol. Rev. 40:143-210.