메뉴 건너뛰기




Volumn 8, Issue 4, 2013, Pages

Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts-Secreted Interferon Beta

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; PHOSPHOPROTEIN; PROTEIN WIG1; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; UNCLASSIFIED DRUG;

EID: 84876447018     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061353     Document Type: Article
Times cited : (34)

References (63)
  • 1
    • 20444412646 scopus 로고    scopus 로고
    • Therapeutic targeting of the tumor microenvironment
    • Joyce JA, (2005) Therapeutic targeting of the tumor microenvironment. Cancer Cell 7: 513-520.
    • (2005) Cancer Cell , vol.7 , pp. 513-520
    • Joyce, J.A.1
  • 2
    • 70350683363 scopus 로고    scopus 로고
    • The tumor microenvironment: the making of a paradigm
    • Witz IP, (2009) The tumor microenvironment: the making of a paradigm. Cancer Microenviron 2 Suppl 1: 9-17.
    • (2009) Cancer Microenviron , vol.2 , Issue.SUPPL. 1 , pp. 9-17
    • Witz, I.P.1
  • 3
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 79955562722 scopus 로고    scopus 로고
    • Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer
    • Navab R, Strumpf D, Bandarchi B, Zhu CQ, Pintilie M, et al. (2011) Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer. Proc Natl Acad Sci U S A 108: 7160-7165.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7160-7165
    • Navab, R.1    Strumpf, D.2    Bandarchi, B.3    Zhu, C.Q.4    Pintilie, M.5
  • 5
    • 33845389417 scopus 로고    scopus 로고
    • Distinctive gene expression of prostatic stromal cells cultured from diseased versus normal tissues
    • Zhao H, Ramos CF, Brooks JD, Peehl DM, (2007) Distinctive gene expression of prostatic stromal cells cultured from diseased versus normal tissues. J Cell Physiol 210: 111-121.
    • (2007) J Cell Physiol , vol.210 , pp. 111-121
    • Zhao, H.1    Ramos, C.F.2    Brooks, J.D.3    Peehl, D.M.4
  • 6
    • 0018610803 scopus 로고
    • Enhanced collagenase production by fibroblasts derived from human basal cell carcinomas
    • Bauer EA, Uitto J, Walters RC, Eisen AZ, (1979) Enhanced collagenase production by fibroblasts derived from human basal cell carcinomas. Cancer Res 39: 4594-4599.
    • (1979) Cancer Res , vol.39 , pp. 4594-4599
    • Bauer, E.A.1    Uitto, J.2    Walters, R.C.3    Eisen, A.Z.4
  • 7
    • 0031975384 scopus 로고    scopus 로고
    • Paracrine/autocrine regulation of breast cancer by the insulin-like growth factors
    • Rasmussen AA, Cullen KJ, (1998) Paracrine/autocrine regulation of breast cancer by the insulin-like growth factors. Breast Cancer Res Treat 47: 219-233.
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 219-233
    • Rasmussen, A.A.1    Cullen, K.J.2
  • 8
    • 0023718895 scopus 로고
    • Stromal involvement in malignant growth
    • van den Hooff A, (1988) Stromal involvement in malignant growth. Adv Cancer Res 50: 159-196.
    • (1988) Adv Cancer Res , vol.50 , pp. 159-196
    • van den Hooff, A.1
  • 9
    • 58949102960 scopus 로고    scopus 로고
    • Modulated expression of WFDC1 during carcinogenesis and cellular senescence
    • Madar S, Brosh R, Buganim Y, Ezra O, Goldstein I, et al. (2009) Modulated expression of WFDC1 during carcinogenesis and cellular senescence. Carcinogenesis 30: 20-27.
    • (2009) Carcinogenesis , vol.30 , pp. 20-27
    • Madar, S.1    Brosh, R.2    Buganim, Y.3    Ezra, O.4    Goldstein, I.5
  • 10
    • 81855217391 scopus 로고    scopus 로고
    • Transcriptional activity of ATF3 in the stromal compartment of tumors promotes cancer progression
    • Buganim Y, Madar S, Rais Y, Pomeraniec L, Harel E, et al. (2011) Transcriptional activity of ATF3 in the stromal compartment of tumors promotes cancer progression. Carcinogenesis 32: 1749-1757.
    • (2011) Carcinogenesis , vol.32 , pp. 1749-1757
    • Buganim, Y.1    Madar, S.2    Rais, Y.3    Pomeraniec, L.4    Harel, E.5
  • 11
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the Light: The Growing Complexity of p53
    • Vousden KH, Prives C, (2009) Blinded by the Light: The Growing Complexity of p53. Cell 137: 413-431.
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 12
    • 81355154522 scopus 로고    scopus 로고
    • Mutant p53 gain of function is interwoven into the hallmarks of cancer
    • Solomon H, Madar S, Rotter V, (2011) Mutant p53 gain of function is interwoven into the hallmarks of cancer. J Pathol 225: 475-478.
    • (2011) J Pathol , vol.225 , pp. 475-478
    • Solomon, H.1    Madar, S.2    Rotter, V.3
  • 13
    • 78649930457 scopus 로고    scopus 로고
    • p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner
    • Addadi Y, Moskovits N, Granot D, Lozano G, Carmi Y, et al. (2010) p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner. Cancer Res 70: 9650-9658.
    • (2010) Cancer Res , vol.70 , pp. 9650-9658
    • Addadi, Y.1    Moskovits, N.2    Granot, D.3    Lozano, G.4    Carmi, Y.5
  • 14
    • 33644696628 scopus 로고    scopus 로고
    • Analysis of p53 and vascular endothelial growth factor expression in human gallbladder carcinoma for the determination of tumor vascularity
    • Tian Y, Ding RY, Zhi YH, Guo RX, Wu SD, (2006) Analysis of p53 and vascular endothelial growth factor expression in human gallbladder carcinoma for the determination of tumor vascularity. World J Gastroenterol 12: 415-419.
    • (2006) World J Gastroenterol , vol.12 , pp. 415-419
    • Tian, Y.1    Ding, R.Y.2    Zhi, Y.H.3    Guo, R.X.4    Wu, S.D.5
  • 15
    • 32144464204 scopus 로고    scopus 로고
    • P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients
    • Famulski W, Sulkowska M, Wincewicz A, Kedra B, Pawlak K, et al. (2006) P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients. Neoplasma 53: 43-48.
    • (2006) Neoplasma , vol.53 , pp. 43-48
    • Famulski, W.1    Sulkowska, M.2    Wincewicz, A.3    Kedra, B.4    Pawlak, K.5
  • 16
    • 70349791957 scopus 로고    scopus 로고
    • The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis
    • Fontemaggi G, Dell'Orso S, Trisciuoglio D, Shay T, Melucci E, et al. (2009) The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis. Nat Struct Mol Biol 16: 1086-1093.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1086-1093
    • Fontemaggi, G.1    Dell'Orso, S.2    Trisciuoglio, D.3    Shay, T.4    Melucci, E.5
  • 17
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon-mediated signalling
    • Platanias LC, (2005) Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 5: 375-386.
    • (2005) Nat Rev Immunol , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 18
    • 7944220831 scopus 로고    scopus 로고
    • Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents
    • Studeny M, Marini FC, Dembinski JL, Zompetta C, Cabreira-Hansen M, et al. (2004) Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. J Natl Cancer Inst 96: 1593-1603.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1593-1603
    • Studeny, M.1    Marini, F.C.2    Dembinski, J.L.3    Zompetta, C.4    Cabreira-Hansen, M.5
  • 20
    • 80052301269 scopus 로고    scopus 로고
    • Interferon-beta signaling contributes to Ras transformation
    • Tsai YC, Pestka S, Wang LH, Runnels LW, Wan S, et al. (2011) Interferon-beta signaling contributes to Ras transformation. PLoS One 6: e24291.
    • (2011) PLoS One , vol.6
    • Tsai, Y.C.1    Pestka, S.2    Wang, L.H.3    Runnels, L.W.4    Wan, S.5
  • 21
    • 34547618258 scopus 로고    scopus 로고
    • IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors
    • Tjandra SS, Hsu C, Goh YI, Gurung A, Poon R, et al. (2007) IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors. Cancer Res 67: 7124-7131.
    • (2007) Cancer Res , vol.67 , pp. 7124-7131
    • Tjandra, S.S.1    Hsu, C.2    Goh, Y.I.3    Gurung, A.4    Poon, R.5
  • 22
    • 0041662272 scopus 로고    scopus 로고
    • Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence
    • Takaoka A, Hayakawa S, Yanai H, Stoiber D, Negishi H, et al. (2003) Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 424: 516-523.
    • (2003) Nature , vol.424 , pp. 516-523
    • Takaoka, A.1    Hayakawa, S.2    Yanai, H.3    Stoiber, D.4    Negishi, H.5
  • 23
    • 84861205347 scopus 로고    scopus 로고
    • Interferon-beta induces cellular senescence in cutaneous human papilloma virus-transformed human keratinocytes by affecting p53 transactivating activity
    • Chiantore MV, Vannucchi S, Accardi R, Tommasino M, Percario ZA, et al. (2012) Interferon-beta induces cellular senescence in cutaneous human papilloma virus-transformed human keratinocytes by affecting p53 transactivating activity. PLoS One 7: e36909.
    • (2012) PLoS One , vol.7
    • Chiantore, M.V.1    Vannucchi, S.2    Accardi, R.3    Tommasino, M.4    Percario, Z.A.5
  • 24
    • 68249142906 scopus 로고    scopus 로고
    • Identification and characterization of the interferon-beta-mediated p53 signal pathway in human peripheral blood mononuclear cells
    • Zhang F, Sriram S, (2009) Identification and characterization of the interferon-beta-mediated p53 signal pathway in human peripheral blood mononuclear cells. Immunology 128: e905-918.
    • (2009) Immunology , vol.128
    • Zhang, F.1    Sriram, S.2
  • 25
    • 0032759944 scopus 로고    scopus 로고
    • Mechanical force-induced signal transduction in lung cells
    • Liu M, Tanswell AK, Post M, (1999) Mechanical force-induced signal transduction in lung cells. Am J Physiol 277: L667-683.
    • (1999) Am J Physiol , vol.277
    • Liu, M.1    Tanswell, A.K.2    Post, M.3
  • 26
    • 0141506116 scopus 로고    scopus 로고
    • CLICK and EXPANDER: a system for clustering and visualizing gene expression data
    • Sharan R, Maron-Katz A, Shamir R, (2003) CLICK and EXPANDER: a system for clustering and visualizing gene expression data. Bioinformatics 19: 1787-1799.
    • (2003) Bioinformatics , vol.19 , pp. 1787-1799
    • Sharan, R.1    Maron-Katz, A.2    Shamir, R.3
  • 27
    • 0034565041 scopus 로고    scopus 로고
    • CLICK: a clustering algorithm with applications to gene expression analysis
    • Sharan R, Shamir R, (2000) CLICK: a clustering algorithm with applications to gene expression analysis. Proc Int Conf Intell Syst Mol Biol 8: 307-316.
    • (2000) Proc Int Conf Intell Syst Mol Biol , vol.8 , pp. 307-316
    • Sharan, R.1    Shamir, R.2
  • 28
    • 84876446920 scopus 로고    scopus 로고
    • Ingenuity Website. Available:. Accessed 2012Sep 1
    • Ingenuity Website. Available: www.ingenuity.com. Accessed 2012Sep 1.
  • 29
    • 38849160275 scopus 로고    scopus 로고
    • Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer
    • Buess M, Nuyten DS, Hastie T, Nielsen T, Pesich R, et al. (2007) Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer. Genome Biol 8: R191.
    • (2007) Genome Biol , vol.8
    • Buess, M.1    Nuyten, D.S.2    Hastie, T.3    Nielsen, T.4    Pesich, R.5
  • 32
    • 0037008742 scopus 로고    scopus 로고
    • Regulation of receptor activator of NF-kappa B ligand-induced osteoclastogenesis by endogenous interferon-beta (INF-beta) and suppressors of cytokine signaling (SOCS). The possible counteracting role of SOCSs- in IFN-beta-inhibited osteoclast formation
    • Hayashi T, Kaneda T, Toyama Y, Kumegawa M, Hakeda Y, (2002) Regulation of receptor activator of NF-kappa B ligand-induced osteoclastogenesis by endogenous interferon-beta (INF-beta) and suppressors of cytokine signaling (SOCS). The possible counteracting role of SOCSs- in IFN-beta-inhibited osteoclast formation. J Biol Chem 277: 27880-27886.
    • (2002) J Biol Chem , vol.277 , pp. 27880-27886
    • Hayashi, T.1    Kaneda, T.2    Toyama, Y.3    Kumegawa, M.4    Hakeda, Y.5
  • 33
    • 69549129472 scopus 로고    scopus 로고
    • TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells
    • Kaiser F, Cook D, Papoutsopoulou S, Rajsbaum R, Wu X, et al. (2009) TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells. J Exp Med 206: 1863-1871.
    • (2009) J Exp Med , vol.206 , pp. 1863-1871
    • Kaiser, F.1    Cook, D.2    Papoutsopoulou, S.3    Rajsbaum, R.4    Wu, X.5
  • 34
    • 67650088521 scopus 로고    scopus 로고
    • Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth
    • Fillmore RA, Mitra A, Xi Y, Ju J, Scammell J, et al. (2009) Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth. Int J Cancer 125: 556-564.
    • (2009) Int J Cancer , vol.125 , pp. 556-564
    • Fillmore, R.A.1    Mitra, A.2    Xi, Y.3    Ju, J.4    Scammell, J.5
  • 35
    • 67649386169 scopus 로고    scopus 로고
    • Inhibition of tumor cell motility by the interferon-inducible GTPase MxA
    • Mushinski JF, Nguyen P, Stevens LM, Khanna C, Lee S, et al. (2009) Inhibition of tumor cell motility by the interferon-inducible GTPase MxA. J Biol Chem 284: 15206-15214.
    • (2009) J Biol Chem , vol.284 , pp. 15206-15214
    • Mushinski, J.F.1    Nguyen, P.2    Stevens, L.M.3    Khanna, C.4    Lee, S.5
  • 36
    • 78651289008 scopus 로고    scopus 로고
    • Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells
    • Kogan-Sakin I, Tabach Y, Buganim Y, Molchadsky A, Solomon H, et al. (2011) Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells. Cell Death Differ 18: 271-281.
    • (2011) Cell Death Differ , vol.18 , pp. 271-281
    • Kogan-Sakin, I.1    Tabach, Y.2    Buganim, Y.3    Molchadsky, A.4    Solomon, H.5
  • 37
    • 84880305826 scopus 로고    scopus 로고
    • Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis
    • Dong P, Karaayvaz M, Jia N, Kaneuchi M, Hamada J, et al. (2012) Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis. Oncogene.
    • (2012) Oncogene
    • Dong, P.1    Karaayvaz, M.2    Jia, N.3    Kaneuchi, M.4    Hamada, J.5
  • 38
    • 72249100428 scopus 로고    scopus 로고
    • Mutant p53 drives invasion by promoting integrin recycling
    • Muller PA, Caswell PT, Doyle B, Iwanicki MP, Tan EH, et al. (2009) Mutant p53 drives invasion by promoting integrin recycling. Cell 139: 1327-1341.
    • (2009) Cell , vol.139 , pp. 1327-1341
    • Muller, P.A.1    Caswell, P.T.2    Doyle, B.3    Iwanicki, M.P.4    Tan, E.H.5
  • 41
    • 33846526235 scopus 로고    scopus 로고
    • Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals
    • Chang WL, Coro ES, Rau FC, Xiao Y, Erle DJ, et al. (2007) Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals. J Immunol 178: 1457-1467.
    • (2007) J Immunol , vol.178 , pp. 1457-1467
    • Chang, W.L.1    Coro, E.S.2    Rau, F.C.3    Xiao, Y.4    Erle, D.J.5
  • 42
    • 24744452216 scopus 로고    scopus 로고
    • IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide
    • Natsume A, Ishii D, Wakabayashi T, Tsuno T, Hatano H, et al. (2005) IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide. Cancer Res 65: 7573-7579.
    • (2005) Cancer Res , vol.65 , pp. 7573-7579
    • Natsume, A.1    Ishii, D.2    Wakabayashi, T.3    Tsuno, T.4    Hatano, H.5
  • 43
    • 0030802364 scopus 로고    scopus 로고
    • A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
    • Israeli D, Tessler E, Haupt Y, Elkeles A, Wilder S, et al. (1997) A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. Embo J 16: 4384-4392.
    • (1997) Embo J , vol.16 , pp. 4384-4392
    • Israeli, D.1    Tessler, E.2    Haupt, Y.3    Elkeles, A.4    Wilder, S.5
  • 44
    • 0030693589 scopus 로고    scopus 로고
    • Wig-1, a new p53-induced gene encoding a zinc finger protein
    • Varmeh-Ziaie S, Okan I, Wang Y, Magnusson KP, Warthoe P, et al. (1997) Wig-1, a new p53-induced gene encoding a zinc finger protein. Oncogene 15: 2699-2704.
    • (1997) Oncogene , vol.15 , pp. 2699-2704
    • Varmeh-Ziaie, S.1    Okan, I.2    Wang, Y.3    Magnusson, K.P.4    Warthoe, P.5
  • 45
    • 43249104714 scopus 로고    scopus 로고
    • Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells
    • Junk DJ, Vrba L, Watts GS, Oshiro MM, Martinez JD, et al. (2008) Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia 10: 450-461.
    • (2008) Neoplasia , vol.10 , pp. 450-461
    • Junk, D.J.1    Vrba, L.2    Watts, G.S.3    Oshiro, M.M.4    Martinez, J.D.5
  • 46
    • 80051745688 scopus 로고    scopus 로고
    • The p53 target Wig-1: a regulator of mRNA stability and stem cell fate?
    • Vilborg A, Bersani C, Wilhelm MT, Wiman KG, (2011) The p53 target Wig-1: a regulator of mRNA stability and stem cell fate? Cell Death Differ 18: 1434-1440.
    • (2011) Cell Death Differ , vol.18 , pp. 1434-1440
    • Vilborg, A.1    Bersani, C.2    Wilhelm, M.T.3    Wiman, K.G.4
  • 47
    • 0025964061 scopus 로고
    • Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein
    • Ginsberg D, Michael-Michalovitz D, Oren M, (1991) Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein. Mol Cell Biol 11: 582-585.
    • (1991) Mol Cell Biol , vol.11 , pp. 582-585
    • Ginsberg, D.1    Michael-Michalovitz, D.2    Oren, M.3
  • 48
    • 79952724783 scopus 로고    scopus 로고
    • Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
    • De Monte L, Reni M, Tassi E, Clavenna D, Papa I, et al. (2011) Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J Exp Med 208: 469-478.
    • (2011) J Exp Med , vol.208 , pp. 469-478
    • De Monte, L.1    Reni, M.2    Tassi, E.3    Clavenna, D.4    Papa, I.5
  • 49
    • 76349096670 scopus 로고    scopus 로고
    • Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner
    • Erez N, Truitt M, Olson P, Arron ST, Hanahan D, (2010) Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner. Cancer Cell 17: 135-147.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3    Arron, S.T.4    Hanahan, D.5
  • 50
    • 64349089164 scopus 로고    scopus 로고
    • Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1
    • Kogan-Sakin I, Cohen M, Paland N, Madar S, Solomon H, et al. (2009) Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1. Carcinogenesis 30: 698-705.
    • (2009) Carcinogenesis , vol.30 , pp. 698-705
    • Kogan-Sakin, I.1    Cohen, M.2    Paland, N.3    Madar, S.4    Solomon, H.5
  • 51
    • 36349034540 scopus 로고    scopus 로고
    • Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
    • Mueller L, Goumas FA, Affeldt M, Sandtner S, Gehling UM, et al. (2007) Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment. Am J Pathol 171: 1608-1618.
    • (2007) Am J Pathol , vol.171 , pp. 1608-1618
    • Mueller, L.1    Goumas, F.A.2    Affeldt, M.3    Sandtner, S.4    Gehling, U.M.5
  • 52
    • 80051525374 scopus 로고    scopus 로고
    • Interleukin 1alpha sustains the expression of inflammatory factors in human pancreatic cancer microenvironment by targeting cancer-associated fibroblasts
    • Tjomsland V, Spangeus A, Valila J, Sandstrom P, Borch K, et al. (2011) Interleukin 1alpha sustains the expression of inflammatory factors in human pancreatic cancer microenvironment by targeting cancer-associated fibroblasts. Neoplasia 13: 664-675.
    • (2011) Neoplasia , vol.13 , pp. 664-675
    • Tjomsland, V.1    Spangeus, A.2    Valila, J.3    Sandstrom, P.4    Borch, K.5
  • 53
    • 79751501829 scopus 로고    scopus 로고
    • Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth
    • Quante M, Tu SP, Tomita H, Gonda T, Wang SS, et al. (2011) Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell 19: 257-272.
    • (2011) Cancer Cell , vol.19 , pp. 257-272
    • Quante, M.1    Tu, S.P.2    Tomita, H.3    Gonda, T.4    Wang, S.S.5
  • 54
    • 79957532451 scopus 로고    scopus 로고
    • Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness
    • Giannoni E, Bianchini F, Calorini L, Chiarugi P, (2011) Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness. Antioxid Redox Signal 14: 2361-2371.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 2361-2371
    • Giannoni, E.1    Bianchini, F.2    Calorini, L.3    Chiarugi, P.4
  • 55
    • 77955382651 scopus 로고    scopus 로고
    • Clinical outcomes and correlates of TP53 mutations and cancer
    • Robles AI, Harris CC, (2010) Clinical outcomes and correlates of TP53 mutations and cancer. Cold Spring Harb Perspect Biol 2: a001016.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Robles, A.I.1    Harris, C.C.2
  • 56
    • 79952357434 scopus 로고    scopus 로고
    • Unleash the wild type: restoration of p53 suppressive activity in skin cancer
    • Madar S, Stambolsky P, Rotter V, (2011) Unleash the wild type: restoration of p53 suppressive activity in skin cancer. Cell Cycle 10: 736-737.
    • (2011) Cell Cycle , vol.10 , pp. 736-737
    • Madar, S.1    Stambolsky, P.2    Rotter, V.3
  • 57
    • 24044466754 scopus 로고    scopus 로고
    • Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs
    • Bykov VJ, Issaeva N, Zache N, Shilov A, Hultcrantz M, et al. (2005) Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs. J Biol Chem 280: 30384-30391.
    • (2005) J Biol Chem , vol.280 , pp. 30384-30391
    • Bykov, V.J.1    Issaeva, N.2    Zache, N.3    Shilov, A.4    Hultcrantz, M.5
  • 58
    • 0033601370 scopus 로고    scopus 로고
    • Pharmacological rescue of mutant p53 conformation and function
    • Foster BA, Coffey HA, Morin MJ, Rastinejad F, (1999) Pharmacological rescue of mutant p53 conformation and function. Science 286: 2507-2510.
    • (1999) Science , vol.286 , pp. 2507-2510
    • Foster, B.A.1    Coffey, H.A.2    Morin, M.J.3    Rastinejad, F.4
  • 60
    • 79960116603 scopus 로고    scopus 로고
    • Interferon: current status and future prospects in cancer therapy
    • Wang BX, Rahbar R, Fish EN, (2011) Interferon: current status and future prospects in cancer therapy. J Interferon Cytokine Res 31: 545-552.
    • (2011) J Interferon Cytokine Res , vol.31 , pp. 545-552
    • Wang, B.X.1    Rahbar, R.2    Fish, E.N.3
  • 61
    • 29644436953 scopus 로고    scopus 로고
    • p73, a sophisticated p53 family member in the cancer world
    • Ozaki T, Nakagawara A, (2005) p73, a sophisticated p53 family member in the cancer world. Cancer Sci 96: 729-737.
    • (2005) Cancer Sci , vol.96 , pp. 729-737
    • Ozaki, T.1    Nakagawara, A.2
  • 62
    • 79958279832 scopus 로고    scopus 로고
    • p53-paralog DNp73 oncogene is repressed by IFNalpha/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor
    • Testoni B, Schinzari V, Guerrieri F, Gerbal-Chaloin S, Blandino G, et al. (2011) p53-paralog DNp73 oncogene is repressed by IFNalpha/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor. Oncogene 30: 2670-2678.
    • (2011) Oncogene , vol.30 , pp. 2670-2678
    • Testoni, B.1    Schinzari, V.2    Guerrieri, F.3    Gerbal-Chaloin, S.4    Blandino, G.5
  • 63
    • 0242333835 scopus 로고    scopus 로고
    • Normalization of cDNA microarray data
    • Smyth GK, Speed T, (2003) Normalization of cDNA microarray data. Methods 31: 265-273.
    • (2003) Methods , vol.31 , pp. 265-273
    • Smyth, G.K.1    Speed, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.