메뉴 건너뛰기




Volumn 60, Issue 6, 2013, Pages 964-971

Children's Oncology Group's 2013 blueprint for research: Acute myeloid leukemia

Author keywords

Acute myeloid leukemia; Children's oncology group

Indexed keywords

ANTHRACYCLINE; ARSENIC TRIOXIDE; BORTEZOMIB; IMATINIB; SORAFENIB;

EID: 84876424234     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24432     Document Type: Review
Times cited : (69)

References (93)
  • 1
    • 84868129082 scopus 로고    scopus 로고
    • Diagnosis and management of acute myeloid leukemia in children and adolescents: Recommendations from an international expert panel
    • Creutzig U, van den Heuvel-Eibrink M, Gibson B, et al. Diagnosis and management of acute myeloid leukemia in children and adolescents: Recommendations from an international expert panel. Blood 2012; 120: 3187-3205.
    • (2012) Blood , vol.120 , pp. 3187-3205
    • Creutzig, U.1    van Den Heuvel-Eibrink, M.2    Gibson, B.3
  • 2
    • 84855599530 scopus 로고    scopus 로고
    • Acute leukemia incidence and patient survival among children adults in the United States, 2001-2007
    • Dores GM, Devesa SS, Curtis RE, et al. Acute leukemia incidence and patient survival among children adults in the United States, 2001-2007. Blood 2012; 119: 34-43.
    • (2012) Blood , vol.119 , pp. 34-43
    • Dores, G.M.1    Devesa, S.S.2    Curtis, R.E.3
  • 3
    • 80055064760 scopus 로고    scopus 로고
    • AAML03P1, a pilot study of the safety of Gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia
    • Cooper TM, Franklin J, Gerbing R, et al. AAML03P1, a pilot study of the safety of Gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia. Cancer 2012; 118: 761-769.
    • (2012) Cancer , vol.118 , pp. 761-769
    • Cooper, T.M.1    Franklin, J.2    Gerbing, R.3
  • 4
    • 33845254595 scopus 로고    scopus 로고
    • Clinical implications of FLT3 mutations in pediatric AML
    • Meshinchi S, Alonzo TA, Stirewalt DL, et al. Clinical implications of FLT3 mutations in pediatric AML. Blood 2006; 108: 3654-3661.
    • (2006) Blood , vol.108 , pp. 3654-3661
    • Meshinchi, S.1    Alonzo, T.A.2    Stirewalt, D.L.3
  • 5
    • 77952424259 scopus 로고    scopus 로고
    • Molecular alterations of the IDH1 gene in AML: A Children's Oncology Group and Southwest Oncology Group study
    • Ho PA, Alonzo TA, Kopecky KJ, et al. Molecular alterations of the IDH1 gene in AML: A Children's Oncology Group and Southwest Oncology Group study. Leukemia 2010; 24: 909-913.
    • (2010) Leukemia , vol.24 , pp. 909-913
    • Ho, P.A.1    Alonzo, T.A.2    Kopecky, K.J.3
  • 6
    • 79958864954 scopus 로고    scopus 로고
    • Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: A report from the Children's Oncology Group
    • Ho PA, Kutny MA, Alonzo TA, et al. Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: A report from the Children's Oncology Group. Pediatr Blood Cancer 2011; 57: 204-209.
    • (2011) Pediatr Blood Cancer , vol.57 , pp. 204-209
    • Ho, P.A.1    Kutny, M.A.2    Alonzo, T.A.3
  • 7
    • 77958499209 scopus 로고    scopus 로고
    • Prognostic factors in pediatric acute myeloid leukemia
    • Radhi M, Meshinchi S, Gamis A. Prognostic factors in pediatric acute myeloid leukemia. Curr Hematol Malign Rep 2010; 5: 200-206.
    • (2010) Curr Hematol Malign Rep , vol.5 , pp. 200-206
    • Radhi, M.1    Meshinchi, S.2    Gamis, A.3
  • 8
    • 84865406961 scopus 로고    scopus 로고
    • Residual disease detected by multidimensional flow cytometry signifies high relapse risk in patients with de novo acute myeloid leukemia: A report from Children's Oncology Group
    • Loken MR, Alonzo TA, Pardo L, et al. Residual disease detected by multidimensional flow cytometry signifies high relapse risk in patients with de novo acute myeloid leukemia: A report from Children's Oncology Group. Blood 2012; 120: 1581-1588.
    • (2012) Blood , vol.120 , pp. 1581-1588
    • Loken, M.R.1    Alonzo, T.A.2    Pardo, L.3
  • 9
    • 38949185746 scopus 로고    scopus 로고
    • Outcomes in CCG-2961, a Children's Oncology Group Phase 3 Trial for untreated pediatric acute myeloid leukemia: A report from the Children's Oncology Group
    • Lange BJ, Smith FO, Feusner J, et al. Outcomes in CCG-2961, a Children's Oncology Group Phase 3 Trial for untreated pediatric acute myeloid leukemia: A report from the Children's Oncology Group. Blood 2008; 111: 1044-1053.
    • (2008) Blood , vol.111 , pp. 1044-1053
    • Lange, B.J.1    Smith, F.O.2    Feusner, J.3
  • 10
    • 80053972723 scopus 로고    scopus 로고
    • Results of a randomized trial in children with acute myeloid leukaemia: Medical Research Council AML12 trial
    • Gibson BE, Webb DK, Howman AJ, et al. Results of a randomized trial in children with acute myeloid leukaemia: Medical Research Council AML12 trial. Br J Haematol 2011; 155: 366-376.
    • (2011) Br J Haematol , vol.155 , pp. 366-376
    • Gibson, B.E.1    Webb, D.K.2    Howman, A.J.3
  • 11
    • 84867482598 scopus 로고    scopus 로고
    • Study AML-BFM 2004: Improved survival in childhood acute myeloid leukemia without increased toxicity
    • Creutzig U, Zimmerman M, Dworzak M, et al. Study AML-BFM 2004: Improved survival in childhood acute myeloid leukemia without increased toxicity. Blood 2010; 116: 181.
    • (2010) Blood , vol.116 , pp. 181
    • Creutzig, U.1    Zimmerman, M.2    Dworzak, M.3
  • 12
    • 77953483479 scopus 로고    scopus 로고
    • Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: Results of the AML02 multicentre trial
    • Rubnitz JE, Inaba H, Dahl G, et al. Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: Results of the AML02 multicentre trial. Lancet Oncol 2010; 11: 543-552.
    • (2010) Lancet Oncol , vol.11 , pp. 543-552
    • Rubnitz, J.E.1    Inaba, H.2    Dahl, G.3
  • 13
    • 79951972587 scopus 로고    scopus 로고
    • Response-guided induction therapy in pediatric acute myeloid leukemia with excellent remission rate
    • Abrahamsson J, Forestier E, Heldrup J, et al. Response-guided induction therapy in pediatric acute myeloid leukemia with excellent remission rate. J Clin Oncol 2011; 29: 310-315.
    • (2011) J Clin Oncol , vol.29 , pp. 310-315
    • Abrahamsson, J.1    Forestier, E.2    Heldrup, J.3
  • 14
    • 77957711298 scopus 로고    scopus 로고
    • Preliminary results of Southwest Oncology Group study S0106: An international intergroup phase 3 randomized trial comparing the addition of Gemtuzumab ozogamicin to standard induction therapy versus standard induction therapy followed by a second randomization to post-consolidation Gemtuzumab ozogamicin versus no additional therapy for previously untreated acute myeloid leukemia
    • Petersdorf S, Kopecky K, Stuart R, et al. Preliminary results of Southwest Oncology Group study S0106: An international intergroup phase 3 randomized trial comparing the addition of Gemtuzumab ozogamicin to standard induction therapy versus standard induction therapy followed by a second randomization to post-consolidation Gemtuzumab ozogamicin versus no additional therapy for previously untreated acute myeloid leukemia. Blood 2009; 114: 790.
    • (2009) Blood , vol.114 , pp. 790
    • Petersdorf, S.1    Kopecky, K.2    Stuart, R.3
  • 15
    • 70349467775 scopus 로고    scopus 로고
    • Anthracycline dose intensification in acute myeloid leukemia
    • Fernandez HF, Sun Z, Yao X, et al. Anthracycline dose intensification in acute myeloid leukemia. N Engl J Med 2009; 361: 1249-1259.
    • (2009) N Engl J Med , vol.361 , pp. 1249-1259
    • Fernandez, H.F.1    Sun, Z.2    Yao, X.3
  • 16
    • 79952099282 scopus 로고    scopus 로고
    • Identification of patients with acute myeloblastic leukemia who benefit from the addition of Gemtuzumab ozogamicin: Results of the MRC AML15 trial
    • Burnett AK, Hills RK, Milligan D, et al. Identification of patients with acute myeloblastic leukemia who benefit from the addition of Gemtuzumab ozogamicin: Results of the MRC AML15 trial. J Clin Oncol 2011; 29: 369-377.
    • (2011) J Clin Oncol , vol.29 , pp. 369-377
    • Burnett, A.K.1    Hills, R.K.2    Milligan, D.3
  • 17
    • 84876437513 scopus 로고    scopus 로고
    • Personal communication
    • Gibson B. Personal communication. 2012.
    • (2012)
    • Gibson, B.1
  • 18
    • 84876452698 scopus 로고    scopus 로고
    • Treatment outcomes in older adolescent and young adult (AYA) patients with newly diagnosed AML
    • abstr 9506
    • Canner JA, Alonzo TA, Franklin J, et al. Treatment outcomes in older adolescent and young adult (AYA) patients with newly diagnosed AML. J Clin Oncol 2011; 29 (suppl; abstr 9506).
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL
    • Canner, J.A.1    Alonzo, T.A.2    Franklin, J.3
  • 19
    • 84876454105 scopus 로고    scopus 로고
    • COG statistician
    • Alonzo TA. COG statistician.
    • Alonzo, T.A.1
  • 20
    • 84870055817 scopus 로고    scopus 로고
    • Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: Retrospective analysis of the Childhood Cancer Survivor Study cohort
    • Mulrooney DA, Yeazel MW, Kawashima T, et al. Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: Retrospective analysis of the Childhood Cancer Survivor Study cohort. Br Med J 2009; 339: b4606.
    • (2009) Br Med J , vol.339
    • Mulrooney, D.A.1    Yeazel, M.W.2    Kawashima, T.3
  • 21
    • 65549100587 scopus 로고    scopus 로고
    • Late mortality among 5-year survivors of childhood cancer: A summary from the Childhood Cancer Survivor Study
    • Armstrong GT, Liu Q, Yasui Y, et al. Late mortality among 5-year survivors of childhood cancer: A summary from the Childhood Cancer Survivor Study. J Clin Oncol 2009; 27: 2328-2338.
    • (2009) J Clin Oncol , vol.27 , pp. 2328-2338
    • Armstrong, G.T.1    Liu, Q.2    Yasui, Y.3
  • 22
    • 84862983645 scopus 로고    scopus 로고
    • High risk of symptomatic cardiac events in childhood cancer survivors
    • Van der Pal HJ, van Dalen EC, van Delden E, et al. High risk of symptomatic cardiac events in childhood cancer survivors. J Clin Oncol 2012; 30: 1429-1437.
    • (2012) J Clin Oncol , vol.30 , pp. 1429-1437
    • Van der Pal, H.J.1    van Dalen, E.C.2    van Delden, E.3
  • 23
    • 84861906112 scopus 로고    scopus 로고
    • Sorafenib treatment of FLT3-ITD_acute myeloid leukemia: Favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation
    • Man CH, Fung TK, Ho C, et al. Sorafenib treatment of FLT3-ITD_acute myeloid leukemia: Favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. Blood 2012; 119: 5133-5143.
    • (2012) Blood , vol.119 , pp. 5133-5143
    • Man, C.H.1    Fung, T.K.2    Ho, C.3
  • 24
    • 77950612017 scopus 로고    scopus 로고
    • Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML
    • Pollard JA, Alonzo TA, Gerbing RB, et al. Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML. Blood 2010; 115: 2372-2379.
    • (2010) Blood , vol.115 , pp. 2372-2379
    • Pollard, J.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 25
    • 26944447953 scopus 로고    scopus 로고
    • Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia
    • Goemans BF, Zwaan CM, Miller M, et al. Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia. Leukemia 2005; 19: 1536-1542.
    • (2005) Leukemia , vol.19 , pp. 1536-1542
    • Goemans, B.F.1    Zwaan, C.M.2    Miller, M.3
  • 26
    • 84876436273 scopus 로고    scopus 로고
    • Demonstration of significant clonal evolution from diagnosis to relapse in childhood AML determined by exome capture sequencing-An NCI/COG TARGET AML Study
    • Meshinchi S, Ries RE, Farrar J, et al. Demonstration of significant clonal evolution from diagnosis to relapse in childhood AML determined by exome capture sequencing-An NCI/COG TARGET AML Study. Cancer Res 2012; 72: LB-93.
    • (2012) Cancer Res , vol.72
    • Meshinchi, S.1    Ries, R.E.2    Farrar, J.3
  • 27
    • 84876432763 scopus 로고    scopus 로고
    • Dose-intensified daunorubicin induction and consolidation plus combined modality maintenance therapy for children with newly diagnosed acute promyelocytic leukemia (APL): North American Intergroup Study C9710
    • Feusner JH, Gregory J, Moser BK, et al. Dose-intensified daunorubicin induction and consolidation plus combined modality maintenance therapy for children with newly diagnosed acute promyelocytic leukemia (APL): North American Intergroup Study C9710. J Clin Oncol 2010; 28: 15s.
    • (2010) J Clin Oncol , vol.28
    • Feusner, J.H.1    Gregory, J.2    Moser, B.K.3
  • 28
    • 84866492297 scopus 로고    scopus 로고
    • Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group Trial A2971
    • Sorrell AD, Alonzo TA, Hilden JM, et al. Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group Trial A2971. Cancer 2012; 118: 4806-4814.
    • (2012) Cancer , vol.118 , pp. 4806-4814
    • Sorrell, A.D.1    Alonzo, T.A.2    Hilden, J.M.3
  • 29
    • 84255176504 scopus 로고    scopus 로고
    • Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: A report from the Children's Oncology Group Study A2971
    • Gamis AS, Alonzo TA, Gerbing RB, et al. Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: A report from the Children's Oncology Group Study A2971. Blood 2011; 118: 6752-6759.
    • (2011) Blood , vol.118 , pp. 6752-6759
    • Gamis, A.S.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 30
    • 79955733477 scopus 로고    scopus 로고
    • Higher dose imatinib for children with de novo chronic phase chronic myelogenous leukemia: A report from the Children's Oncology Group
    • Champagne MA, Fu CH, Chang M, et al. Higher dose imatinib for children with de novo chronic phase chronic myelogenous leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer 2011; 57: 56-62.
    • (2011) Pediatr Blood Cancer , vol.57 , pp. 56-62
    • Champagne, M.A.1    Fu, C.H.2    Chang, M.3
  • 31
    • 69249229646 scopus 로고    scopus 로고
    • Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): A report from the Children's Oncology Group
    • Ho PA, Alonzo TA, Gerbing RB, et al. Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): A report from the Children's Oncology Group. Blood 2009; 113: 6558-6566.
    • (2009) Blood , vol.113 , pp. 6558-6566
    • Ho, P.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 32
    • 34547954572 scopus 로고    scopus 로고
    • The incidence and clinical significance of nucleophosmin mutations in childhood AML
    • Brown P, McIntyre E, Rau R, et al. The incidence and clinical significance of nucleophosmin mutations in childhood AML. Blood 2007; 110: 979-985.
    • (2007) Blood , vol.110 , pp. 979-985
    • Brown, P.1    McIntyre, E.2    Rau, R.3
  • 33
    • 32644443640 scopus 로고    scopus 로고
    • Randomized use of cyclosporinA(CsA) to modulate P-glycoprotein in children with AML in remission: Pediatric Oncology Group Study 9421
    • Becton D, Dahl GV, Ravindranath Y, et al. Randomized use of cyclosporinA(CsA) to modulate P-glycoprotein in children with AML in remission: Pediatric Oncology Group Study 9421. Blood 2006; 107: 1315-1324.
    • (2006) Blood , vol.107 , pp. 1315-1324
    • Becton, D.1    Dahl, G.V.2    Ravindranath, Y.3
  • 34
    • 79957971261 scopus 로고    scopus 로고
    • Remission rates in childhood acute myeloid leukemia (AML) utilizing a dose-intensive induction regimen with or without Gemtuzumab ozogamicin (GO): Initial results from the Children's Oncology Group Phase III Trial, AAML0531
    • Gamis AS, Alonzo TA, Gerbing RB, et al. Remission rates in childhood acute myeloid leukemia (AML) utilizing a dose-intensive induction regimen with or without Gemtuzumab ozogamicin (GO): Initial results from the Children's Oncology Group Phase III Trial, AAML0531. Blood 2010; 116: 182.
    • (2010) Blood , vol.116 , pp. 182
    • Gamis, A.S.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 35
    • 84876423995 scopus 로고    scopus 로고
    • Identification of post-induction minimal residual disease by multidimensional flow cytometry identifies patients with AML at high risk of relapse and poor outcome-a report from the Children's Oncology Group
    • Meshinchi S, Alonzo TA, Gerbing RB, et al. Identification of post-induction minimal residual disease by multidimensional flow cytometry identifies patients with AML at high risk of relapse and poor outcome-a report from the Children's Oncology Group. Blood 2010; 116: 1702.
    • (2010) Blood , vol.116 , pp. 1702
    • Meshinchi, S.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 36
    • 79952020383 scopus 로고    scopus 로고
    • Improved outcome of patients with low- and intermediate-risk cytogenetics acute myeloid leukemia (AML) in first relapse with Gemtuzumab and cytarabine versus cytarabine
    • Prebet T, Etienne A, Devillier R, et al. Improved outcome of patients with low- and intermediate-risk cytogenetics acute myeloid leukemia (AML) in first relapse with Gemtuzumab and cytarabine versus cytarabine. Cancer 2011; 117: 974-981.
    • (2011) Cancer , vol.117 , pp. 974-981
    • Prebet, T.1    Etienne, A.2    Devillier, R.3
  • 37
    • 84859911350 scopus 로고    scopus 로고
    • Effect of Gemtuzumab ozogamicin on survival of adult patients with denovo acute myeloid leukaemia (ALFA-0701): A randomised, open-label, phase 3 study
    • Castaigne S, Pautus C, Terre C, et al. Effect of Gemtuzumab ozogamicin on survival of adult patients with denovo acute myeloid leukaemia (ALFA-0701): A randomised, open-label, phase 3 study. Lancet 2012; 379: 1508-1516.
    • (2012) Lancet , vol.379 , pp. 1508-1516
    • Castaigne, S.1    Pautus, C.2    Terre, C.3
  • 38
    • 84863522871 scopus 로고    scopus 로고
    • Addition of Gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia
    • Burnett AK, Russell NH, Hills RK, et al. Addition of Gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia. J Clin Oncol 2012; 30: 3924-3931.
    • (2012) J Clin Oncol , vol.30 , pp. 3924-3931
    • Burnett, A.K.1    Russell, N.H.2    Hills, R.K.3
  • 39
    • 77954933160 scopus 로고    scopus 로고
    • Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment Trials AML 10 and 12
    • Harrison CJ, Hills RK, Moorman AV, et al. Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment Trials AML 10 and 12. J Clin Oncol 2010; 28: 2674-2681.
    • (2010) J Clin Oncol , vol.28 , pp. 2674-2681
    • Harrison, C.J.1    Hills, R.K.2    Moorman, A.V.3
  • 40
    • 0038579430 scopus 로고    scopus 로고
    • Immunophenotypic evidence of leukemia after induction therapy predicts relapse: Results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia
    • Sievers EL, Lange BJ, Alonzo TA, et al. Immunophenotypic evidence of leukemia after induction therapy predicts relapse: Results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia. Blood 2003; 101: 3398-3406.
    • (2003) Blood , vol.101 , pp. 3398-3406
    • Sievers, E.L.1    Lange, B.J.2    Alonzo, T.A.3
  • 41
    • 77956429361 scopus 로고    scopus 로고
    • Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol
    • van der Velden VHJ, van der Sluijis-Geling A, Gibson BES, et al. Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol. Leukemia 2010; 24: 1599-1606.
    • (2010) Leukemia , vol.24 , pp. 1599-1606
    • van der Velden, V.H.J.1    van der Sluijis-Geling, A.2    Gibson, B.E.S.3
  • 42
    • 33747066438 scopus 로고    scopus 로고
    • Residual disease monitoring in childhood acute myeloid leukemia by multiparameter flow cytometry: The MRD-AML-BFM Study Group
    • Langebrake C, Creutzig U, Dworzak M, et al. Residual disease monitoring in childhood acute myeloid leukemia by multiparameter flow cytometry: The MRD-AML-BFM Study Group. J Clin Oncol 2006; 24: 3686-3692.
    • (2006) J Clin Oncol , vol.24 , pp. 3686-3692
    • Langebrake, C.1    Creutzig, U.2    Dworzak, M.3
  • 43
    • 84855392404 scopus 로고    scopus 로고
    • Conventional cytogenetics, molecular profiling, and flow cytometric response data allow the creation of a two-tiered risk-group system for risk-based therapy allocation in childhood AML-A report from the Children's Oncology Group
    • Alonzo TA, Ho PA, Gerbing RB, et al. Conventional cytogenetics, molecular profiling, and flow cytometric response data allow the creation of a two-tiered risk-group system for risk-based therapy allocation in childhood AML-A report from the Children's Oncology Group. Blood 2010; 116: 761.
    • (2010) Blood , vol.116 , pp. 761
    • Alonzo, T.A.1    Ho, P.A.2    Gerbing, R.B.3
  • 44
    • 84876432844 scopus 로고    scopus 로고
    • Correlation of CD 33 expression level with disease characteristics and response to Gemtuzumab ozogamycin-containing chemotherapy in childhood AML
    • Pollard JA, Alonzo T, Gerbing R, et al. Correlation of CD 33 expression level with disease characteristics and response to Gemtuzumab ozogamycin-containing chemotherapy in childhood AML. Blood 2008; 112: 148.
    • (2008) Blood , vol.112 , pp. 148
    • Pollard, J.A.1    Alonzo, T.2    Gerbing, R.3
  • 45
    • 77956398973 scopus 로고    scopus 로고
    • High expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology group
    • Walter RB, Alonzo TA, Gerbing RB, et al. High expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology group. J Clin Oncol 2010; 28: 2831-2838.
    • (2010) J Clin Oncol , vol.28 , pp. 2831-2838
    • Walter, R.B.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 46
    • 84876432422 scopus 로고    scopus 로고
    • Sincle cell network profiling (SCNP)-based classifier to predict response to induction therapy in pediatric patients with de novo acute myeloid leukemia (AML): Validation study results
    • Lacayo NJ, Alonzo TA, Gayko U, et al. Sincle cell network profiling (SCNP)-based classifier to predict response to induction therapy in pediatric patients with de novo acute myeloid leukemia (AML): Validation study results. Blood 2011; 118: 3544.
    • (2011) Blood , vol.118 , pp. 3544
    • Lacayo, N.J.1    Alonzo, T.A.2    Gayko, U.3
  • 47
    • 79958808843 scopus 로고    scopus 로고
    • TET2 SNP rs2454206 (I1762V) correlates with improved survival in pediatric acute myelogenous leukemia, a report from the Children's Oncology Group
    • Kutny MA, Alonzo TA, Gerbing RB, et al. TET2 SNP rs2454206 (I1762V) correlates with improved survival in pediatric acute myelogenous leukemia, a report from the Children's Oncology Group. Blood 2010; 116: 949.
    • (2010) Blood , vol.116 , pp. 949
    • Kutny, M.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 48
    • 84876447555 scopus 로고    scopus 로고
    • FLT3 is a stratification factor for targeted therapy treatments in adult and pediatric AML-Phase III trials
    • Meshinchi S. FLT3 is a stratification factor for targeted therapy treatments in adult and pediatric AML-Phase III trials. Eur J Cancer 2011; 47: SP 126.
    • (2011) Eur J Cancer , vol.47
    • Meshinchi, S.1
  • 49
    • 84876446243 scopus 로고    scopus 로고
    • RUNX1 mutations in pediatric AML: A report from the Children's Oncology Group
    • Kutny MA, Alonzo TA, Gerbing RB, et al. RUNX1 mutations in pediatric AML: A report from the Children's Oncology Group. Blood 2009; 114: 2614.
    • (2009) Blood , vol.114 , pp. 2614
    • Kutny, M.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 50
    • 77956275074 scopus 로고    scopus 로고
    • Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): A report from the Children's Oncology Group
    • Ho PA, Zeng R, Alonzo TA, et al. Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): A report from the Children's Oncology Group. Blood 2010; 116: 702-710.
    • (2010) Blood , vol.116 , pp. 702-710
    • Ho, P.A.1    Zeng, R.2    Alonzo, T.A.3
  • 51
    • 78650459322 scopus 로고    scopus 로고
    • C/EBP alpha regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations
    • Pulikkan JA, Peramangalam PS, Dengler V, et al. C/EBP alpha regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations. Blood 2010; 116: 5638-5649.
    • (2010) Blood , vol.116 , pp. 5638-5649
    • Pulikkan, J.A.1    Peramangalam, P.S.2    Dengler, V.3
  • 52
    • 79952074022 scopus 로고    scopus 로고
    • WT1 synonymous single nucleotide polymorphism rs16754 correlates with higher mRNA expression and predicts significantly improved outcome in favorable-risk pediatric acute myeloid leukemia: A report from the children's oncology group
    • Ho PA, Kuhn J, Gerbing RB, et al. WT1 synonymous single nucleotide polymorphism rs16754 correlates with higher mRNA expression and predicts significantly improved outcome in favorable-risk pediatric acute myeloid leukemia: A report from the children's oncology group. J Clin Oncol 2011; 29: 704-711.
    • (2011) J Clin Oncol , vol.29 , pp. 704-711
    • Ho, P.A.1    Kuhn, J.2    Gerbing, R.B.3
  • 53
    • 79958137362 scopus 로고    scopus 로고
    • Prevalence and clinical implications of NRAS mutations in childhood AML: A report from the Children's Oncology Group
    • Berman JN, Gerbing RB, Alonzo TA, et al. Prevalence and clinical implications of NRAS mutations in childhood AML: A report from the Children's Oncology Group. Leukemia 2011; 25: 1039-1042.
    • (2011) Leukemia , vol.25 , pp. 1039-1042
    • Berman, J.N.1    Gerbing, R.B.2    Alonzo, T.A.3
  • 54
    • 80055096047 scopus 로고    scopus 로고
    • Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric/adult AML: A report from the Children's Oncology Group and SWOG
    • Ho PA, Kopecky KJ, Alonzo TA, et al. Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric/adult AML: A report from the Children's Oncology Group and SWOG. Blood 2011; 118: 4561-4566.
    • (2011) Blood , vol.118 , pp. 4561-4566
    • Ho, P.A.1    Kopecky, K.J.2    Alonzo, T.A.3
  • 55
    • 84876428484 scopus 로고    scopus 로고
    • Integrative screening approach to identify regulators of polyploidization and targets for acute megakaryocytic leukemia
    • Wen Q, Goldenson B, Silver S, et al. Integrative screening approach to identify regulators of polyploidization and targets for acute megakaryocytic leukemia. Cell 2012; 150: 1-15.
    • (2012) Cell , vol.150 , pp. 1-15
    • Wen, Q.1    Goldenson, B.2    Silver, S.3
  • 56
    • 84860221813 scopus 로고    scopus 로고
    • Single cell network profiling (SCNP) signatures predict response to induction therapy and relapse risk in pediatric patients with acute myeloid leukemia: Children's Oncology Group (COG) Study POG-9421
    • Lacayo NJ, Cohen A, Westfall M, et al. Single cell network profiling (SCNP) signatures predict response to induction therapy and relapse risk in pediatric patients with acute myeloid leukemia: Children's Oncology Group (COG) Study POG-9421. Blood 2010; 116: 954.
    • (2010) Blood , vol.116 , pp. 954
    • Lacayo, N.J.1    Cohen, A.2    Westfall, M.3
  • 57
    • 84876451596 scopus 로고    scopus 로고
    • FACS analysis of Stat3/5 signaling reveals ligand sensitivity as a significant prognostic factor in pediatric AML: A Children's Oncology Group Report
    • Redell MS, Ruiz MJ, Gerbing RB, et al. FACS analysis of Stat3/5 signaling reveals ligand sensitivity as a significant prognostic factor in pediatric AML: A Children's Oncology Group Report. Blood 2011; 118: 938.
    • (2011) Blood , vol.118 , pp. 938
    • Redell, M.S.1    Ruiz, M.J.2    Gerbing, R.B.3
  • 58
    • 79955713550 scopus 로고    scopus 로고
    • Continuous and high-dose cytarabine combined chemotherapy in children with Down syndrome and acute myeloid leukemia: Report from the Japanese Children's Cancer and Leukemia Study Group (JCCLSG) AML 9805 Down Study
    • Taga T, Shimomura Y, Horikoshi Y, et al. Continuous and high-dose cytarabine combined chemotherapy in children with Down syndrome and acute myeloid leukemia: Report from the Japanese Children's Cancer and Leukemia Study Group (JCCLSG) AML 9805 Down Study. Pediatr Blood Cancer 2011; 57: 36-40.
    • (2011) Pediatr Blood Cancer , vol.57 , pp. 36-40
    • Taga, T.1    Shimomura, Y.2    Horikoshi, Y.3
  • 59
    • 77951752828 scopus 로고    scopus 로고
    • Myeloid leukaemia in children with Down syndrome: Report of the registry-based French experience between 1990 and 2003
    • Tandonnet J, Clavel J, Baruchel A, et al. Myeloid leukaemia in children with Down syndrome: Report of the registry-based French experience between 1990 and 2003. Pediatr Blood Cancer 2010; 54: 927-933.
    • (2010) Pediatr Blood Cancer , vol.54 , pp. 927-933
    • Tandonnet, J.1    Clavel, J.2    Baruchel, A.3
  • 60
    • 33646676254 scopus 로고    scopus 로고
    • Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: Data from 56 children treated on NOPHO-AML protocols and a review of the literature
    • Abildggaard L, Ellebaek E, Gustafsson G, et al. Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: Data from 56 children treated on NOPHO-AML protocols and a review of the literature. Ann Hematol 2006; 85: 275-280.
    • (2006) Ann Hematol , vol.85 , pp. 275-280
    • Abildggaard, L.1    Ellebaek, E.2    Gustafsson, G.3
  • 61
    • 36849053313 scopus 로고    scopus 로고
    • Prospective Study of a pirarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: The Japanese Childhood AML Cooperative Study Group
    • Kudo K, Kojima S, Tabuchi K, et al. Prospective Study of a pirarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: The Japanese Childhood AML Cooperative Study Group. J Clin Oncol 2007; 25: 5442-5447.
    • (2007) J Clin Oncol , vol.25 , pp. 5442-5447
    • Kudo, K.1    Kojima, S.2    Tabuchi, K.3
  • 62
    • 18944404989 scopus 로고    scopus 로고
    • AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity
    • Creutzig U, Reinhardt D, Diekamp S, et al. AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity. Leukemia 2005; 19: 1355-1360.
    • (2005) Leukemia , vol.19 , pp. 1355-1360
    • Creutzig, U.1    Reinhardt, D.2    Diekamp, S.3
  • 63
    • 33644905562 scopus 로고    scopus 로고
    • Treatment for myeloid leukaemia of Down syndrome: Population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials
    • Rao A, Hills RK, Stiller C, et al. Treatment for myeloid leukaemia of Down syndrome: Population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials. Br J Haematol 2005; 132: 576-583.
    • (2005) Br J Haematol , vol.132 , pp. 576-583
    • Rao, A.1    Hills, R.K.2    Stiller, C.3
  • 64
    • 84876453487 scopus 로고    scopus 로고
    • Remission marrow blast percentage predicts relapse risk in children with myeloid leukemia associated with Down syndrome
    • Sorrell A, Alonzo TA, Gerbing RB, et al. Remission marrow blast percentage predicts relapse risk in children with myeloid leukemia associated with Down syndrome. Pediatr Blood Cancer 2012; 58: 1039.
    • (2012) Pediatr Blood Cancer , vol.58 , pp. 1039
    • Sorrell, A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 65
    • 77953402940 scopus 로고    scopus 로고
    • Down syndrome patients with relapsed acute myelogenous leukemia
    • Loew T, Gamis A, Smith F, et al. Down syndrome patients with relapsed acute myelogenous leukemia. Blood 2004; 104: 215b.
    • (2004) Blood , vol.104
    • Loew, T.1    Gamis, A.2    Smith, F.3
  • 66
    • 84865763446 scopus 로고    scopus 로고
    • Clinical characteristics and outcome of refractory/relapsed myeloid leukemia in children with Down syndrome
    • Taga T, Saito AM, Kudo K, et al. Clinical characteristics and outcome of refractory/relapsed myeloid leukemia in children with Down syndrome. Blood 2012; 120: 1810-1815.
    • (2012) Blood , vol.120 , pp. 1810-1815
    • Taga, T.1    Saito, A.M.2    Kudo, K.3
  • 67
    • 84864945751 scopus 로고    scopus 로고
    • FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: A report from the Children's Oncology Group
    • Kutny MA, Moser BK, Laumann K, et al. FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer 2012; 59: 662-667.
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 662-667
    • Kutny, M.A.1    Moser, B.K.2    Laumann, K.3
  • 68
    • 17044409146 scopus 로고    scopus 로고
    • GIMEMA-AIEOP AIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children
    • Testi AM, Biondi A, Lo Coco F, et al. GIMEMA-AIEOP AIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children. Blood 2005; 106: 447-453.
    • (2005) Blood , vol.106 , pp. 447-453
    • Testi, A.M.1    Biondi, A.2    Lo Coco, F.3
  • 69
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-{kappa}B is constitutively activated in primitive human acute myelogenous leukemia cells
    • Guzman ML, Neering SJ, Upchurch D, et al. Nuclear factor-{kappa}B is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001; 98: 2301-2307.
    • (2001) Blood , vol.98 , pp. 2301-2307
    • Guzman, M.L.1    Neering, S.J.2    Upchurch, D.3
  • 70
    • 33847410207 scopus 로고    scopus 로고
    • The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells
    • Stapnes C, Doskeland AP, Hatfield K, et al. The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells. Br J Haematol 2007; 136: 814-828.
    • (2007) Br J Haematol , vol.136 , pp. 814-828
    • Stapnes, C.1    Doskeland, A.P.2    Hatfield, K.3
  • 71
    • 77951645227 scopus 로고    scopus 로고
    • Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia
    • Ravandi F, Cortes JE, Jones D, et al. Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia. J Clin Oncol 2010; 28: 1856-1862.
    • (2010) J Clin Oncol , vol.28 , pp. 1856-1862
    • Ravandi, F.1    Cortes, J.E.2    Jones, D.3
  • 72
    • 0242329734 scopus 로고    scopus 로고
    • Progenitor cell involvement is predictive of response to induction chemotherapy in paediatric acute myeloid leukaemia
    • Johnston DL, Meshinchi S, Opheim KE, et al. Progenitor cell involvement is predictive of response to induction chemotherapy in paediatric acute myeloid leukaemia. Br J Haematol 2003; 123: 431-435.
    • (2003) Br J Haematol , vol.123 , pp. 431-435
    • Johnston, D.L.1    Meshinchi, S.2    Opheim, K.E.3
  • 73
    • 33750614145 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication in CD34+/CD33- precursors predicts poor outcome in acute myeloid leukemia
    • Pollard JA, Alonzo TA, Gerbing RB, et al. FLT3 internal tandem duplication in CD34+/CD33- precursors predicts poor outcome in acute myeloid leukemia. Blood 2006; 108: 2764-2769.
    • (2006) Blood , vol.108 , pp. 2764-2769
    • Pollard, J.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 74
    • 84865438947 scopus 로고    scopus 로고
    • Multidimensional flow cytometry significantly improves upon the morphologic assessment of post-induction marrow remission status-Comparison of morphology and multidimensional flow cytometry: A report from the Children's Oncology Group AML Protocol AAML0531
    • Loken MR, Alonzo TA, Pardo L, et al. Multidimensional flow cytometry significantly improves upon the morphologic assessment of post-induction marrow remission status-Comparison of morphology and multidimensional flow cytometry: A report from the Children's Oncology Group AML Protocol AAML0531. Blood 2011; 118: 939.
    • (2011) Blood , vol.118 , pp. 939
    • Loken, M.R.1    Alonzo, T.A.2    Pardo, L.3
  • 77
    • 0037062350 scopus 로고    scopus 로고
    • PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model
    • Kelly LM, Kutok JL, Williams IR, et al. PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model. Proc Natl Acad Sci USA 2002; 99: 8283-8288.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8283-8288
    • Kelly, L.M.1    Kutok, J.L.2    Williams, I.R.3
  • 79
    • 84859899567 scopus 로고    scopus 로고
    • Acute myeloid leukemia stem cells and CD33-targeted immunotherapy
    • Walter RB, Applebaum FR, Estey EH, et al. Acute myeloid leukemia stem cells and CD33-targeted immunotherapy. Blood 2012; 119: 6198-6208.
    • (2012) Blood , vol.119 , pp. 6198-6208
    • Walter, R.B.1    Applebaum, F.R.2    Estey, E.H.3
  • 80
    • 84860747223 scopus 로고    scopus 로고
    • Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
    • Smith CC, Wang Q, Chin CS, et al. Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. Nature 2012; 485: 260-263.
    • (2012) Nature , vol.485 , pp. 260-263
    • Smith, C.C.1    Wang, Q.2    Chin, C.S.3
  • 81
    • 84863785488 scopus 로고    scopus 로고
    • Selective FLT3 inhibition of FLT3-ITD(+) acute myeloid leukaemia resulting in secondary D835Y mutation: A model for emerging clinical resistance patterns
    • Moore AS, Faisal A, de Castro DG, et al. Selective FLT3 inhibition of FLT3-ITD(+) acute myeloid leukaemia resulting in secondary D835Y mutation: A model for emerging clinical resistance patterns. Leukemia 2012; 26: 1462-1470.
    • (2012) Leukemia , vol.26 , pp. 1462-1470
    • Moore, A.S.1    Faisal, A.2    de Castro, D.G.3
  • 82
    • 0036798706 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: A model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia
    • Grimwade D, Lo-Coco F. Acute promyelocytic leukemia: A model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia. Leukemia 2002; 16: 1959-1973.
    • (2002) Leukemia , vol.16 , pp. 1959-1973
    • Grimwade, D.1    Lo-Coco, F.2
  • 83
    • 0035525767 scopus 로고    scopus 로고
    • Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: Long-term follow-up in acute promyelocytic leukemia
    • Jurcic JG, Nimer SD, DeBlasio T, et al. Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: Long-term follow-up in acute promyelocytic leukemia. Blood 2001; 98: 2651-2656.
    • (2001) Blood , vol.98 , pp. 2651-2656
    • Jurcic, J.G.1    Nimer, S.D.2    DeBlasio, T.3
  • 84
    • 0041327674 scopus 로고    scopus 로고
    • The importance of molecular monitoring in acute promyelocytic leukaemia
    • Lo-Coco F, Breccia M, Diverio D. The importance of molecular monitoring in acute promyelocytic leukaemia. Best Pract Res Clin Haematol 2003; 16: 503-520.
    • (2003) Best Pract Res Clin Haematol , vol.16 , pp. 503-520
    • Lo-Coco, F.1    Breccia, M.2    Diverio, D.3
  • 85
    • 0027237223 scopus 로고
    • Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA
    • Miller WH Jr, Levine K, DeBlasio A, et al. Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA. Blood 1993; 82: 1689-1694.
    • (1993) Blood , vol.82 , pp. 1689-1694
    • Miller Jr, W.H.1    Levine, K.2    DeBlasio, A.3
  • 86
    • 84867297401 scopus 로고    scopus 로고
    • Minimal residual disease monitoring by RT-qPCR in core-binding factor AML allows risk-stratification and predicts relapse: Results of the UK MRC AML-15 trial
    • Liu Yin JA, O'Brien MA, Hills RK, et al. Minimal residual disease monitoring by RT-qPCR in core-binding factor AML allows risk-stratification and predicts relapse: Results of the UK MRC AML-15 trial. Blood 2012; 120: 2826-2835.
    • (2012) Blood , vol.120 , pp. 2826-2835
    • Liu Yin, J.A.1    O'Brien, M.A.2    Hills, R.K.3
  • 87
    • 0037079730 scopus 로고    scopus 로고
    • Real-time quantitation of minimal residual disease in inv(16)-positive acute myeloid leukemia may indicate risk for clinical relapse and may identify patients in a curable state
    • Buonamici S, Ottaviani E, Testoni N, et al. Real-time quantitation of minimal residual disease in inv(16)-positive acute myeloid leukemia may indicate risk for clinical relapse and may identify patients in a curable state. Blood 2002; 99: 443-449.
    • (2002) Blood , vol.99 , pp. 443-449
    • Buonamici, S.1    Ottaviani, E.2    Testoni, N.3
  • 88
    • 84876445899 scopus 로고    scopus 로고
    • Augmentation of sensitivity of FLT3/ITD assay allows detection of minimal residual disease in stem cell transplant recipients-correlation with flow cytometric MRD assessment
    • Hughes MD, Zeng R, Miller KL, et al. Augmentation of sensitivity of FLT3/ITD assay allows detection of minimal residual disease in stem cell transplant recipients-correlation with flow cytometric MRD assessment. Blood 2010; 116: 1717.
    • (2010) Blood , vol.116 , pp. 1717
    • Hughes, M.D.1    Zeng, R.2    Miller, K.L.3
  • 89
    • 0033301325 scopus 로고    scopus 로고
    • The use of PCR technology for detecting minimal residual disease in patients with leukemia
    • Radich JP. The use of PCR technology for detecting minimal residual disease in patients with leukemia. Rev Immunogenet 1999; 1: 265-278.
    • (1999) Rev Immunogenet , vol.1 , pp. 265-278
    • Radich, J.P.1
  • 90
    • 0034141488 scopus 로고    scopus 로고
    • Molecular quantitation of minimal residual disease in acute myeloid leukemia with t(8;21) can identify patients in durable remission and predict clinical relapse
    • Tobal K, Newton J, Macheta M, et al. Molecular quantitation of minimal residual disease in acute myeloid leukemia with t(8;21) can identify patients in durable remission and predict clinical relapse. Blood 2000; 95: 815-819.
    • (2000) Blood , vol.95 , pp. 815-819
    • Tobal, K.1    Newton, J.2    Macheta, M.3
  • 91
    • 84861120541 scopus 로고    scopus 로고
    • High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia
    • Wu D, Sherwood A, Fromm JR, et al. High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia. Sci Translat Med 2012; 4: 134ra163.
    • (2012) Sci Translat Med , vol.4
    • Wu, D.1    Sherwood, A.2    Fromm, J.R.3
  • 92
    • 84869090342 scopus 로고    scopus 로고
    • High activity of sorafenib in FLT3-ITD-positive acute myeloid leukemia (AML) synergizes with allo-immune effects to induce sustained responses
    • Metzelder S, Shroeder T, Finck A, et al. High activity of sorafenib in FLT3-ITD-positive acute myeloid leukemia (AML) synergizes with allo-immune effects to induce sustained responses. Leukemia 2012; 26: 2353-2359.
    • (2012) Leukemia , vol.26 , pp. 2353-2359
    • Metzelder, S.1    Shroeder, T.2    Finck, A.3
  • 93
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • Ding L, Ley TJ, Larson DE, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 2012; 481: 506-510.
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.