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Volumn 16, Issue 3, 2003, Pages 503-520

The importance of molecular monitoring in acute promyelocytic leukaemia

Author keywords

Acute promyelocytic leukaemia (APL); Minimal residual disease (MRD); PML RAR ; Reverse transcriptase polymerase chain reaction (RT PCR)

Indexed keywords

ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; CALICHEAMICIN; CYTARABINE; GEMTUZUMAB OZOGAMICIN; MONOCLONAL ANTIBODY M 195; NUCLEAR PROTEIN; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; PROMYELOCYTIC LEUKEMIA PROTEIN;

EID: 0041327674     PISSN: 15216926     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1521-6926(03)00041-0     Document Type: Article
Times cited : (29)

References (85)
  • 1
    • 0027957296 scopus 로고
    • Acute promyelocytic leukemia: From genetics to treatment
    • Grignani F, Fagioli M, Alcalay M et al. Acute promyelocytic leukemia: from genetics to treatment. Blood 1994; 83: 10-25.
    • (1994) Blood , vol.83 , pp. 10-25
    • Grignani, F.1    Fagioli, M.2    Alcalay, M.3
  • 2
    • 0028795440 scopus 로고
    • Acute promyelocytic leukemia: From clinic to molecular biology
    • Chen S-J, Wang Z-Y & Chen Z. Acute promyelocytic leukemia: from clinic to molecular biology. Stem Cells 1995; 13: 22-31.
    • (1995) Stem Cells , vol.13 , pp. 22-31
    • Chen, S.-J.1    Wang, Z.-Y.2    Chen, Z.3
  • 3
    • 0029875959 scopus 로고    scopus 로고
    • Pathogenesis and management of acute promyelocytic leukemia
    • Warrell Jr. RP. Pathogenesis and management of acute promyelocytic leukemia. Annual Review of Medicine 1996; 47: 555-565.
    • (1996) Annual Review of Medicine , vol.47 , pp. 555-565
    • Warrell R.P., Jr.1
  • 4
    • 0031052186 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Biology and treatment
    • Fenaux P, Chomienne C & Degos L. Acute promyelocytic leukemia: biology and treatment. Seminars in Oncology 1997; 24: 92-102.
    • (1997) Seminars in Oncology , vol.24 , pp. 92-102
    • Fenaux, P.1    Chomienne, C.2    Degos, L.3
  • 5
    • 0002951049 scopus 로고    scopus 로고
    • Diagnosis and treatment of acute promyelocytic leukemia
    • Wiernik PH, Canellos GP, Dutcher JP and Kyle RA (eds) 3rd edn. New York: Churchill Livingstone
    • Wiernik PH, Gallagher RE & Tallman MS. Diagnosis and treatment of acute promyelocytic leukemia. In Wiernik PH, Canellos GP, Dutcher JP & Kyle RA (eds) Neoplastic Diseases of the Blood, 3rd edn. New York: Churchill Livingstone, 1996, pp 353-380.
    • (1996) Neoplastic Diseases of the Blood , pp. 353-380
    • Wiernik, P.H.1    Gallagher, R.E.2    Tallman, M.S.3
  • 6
    • 0032405602 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: A curable disease
    • Lo Coco F, Nervi C, Avvisati A & Mandelli F. Acute promyelocytic leukemia: a curable disease. Leukemia 1998; 12: 1866-1880.
    • (1998) Leukemia , vol.12 , pp. 1866-1880
    • Lo Coco, F.1    Nervi, C.2    Avvisati, A.3    Mandelli, F.4
  • 7
    • 0036464594 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Evolving therapeutic strategies
    • Tallman MS, Nabhan CH, Feusner JH & Rowe JM. Acute promyelocytic leukemia: evolving therapeutic strategies. Blood 2002; 99: 759-767.
    • (2002) Blood , vol.99 , pp. 759-767
    • Tallman, M.S.1    Nabhan, C.H.2    Feusner, J.H.3    Rowe, J.M.4
  • 8
    • 0032079468 scopus 로고    scopus 로고
    • The impact of all-trans retinoic acid on the coagulopathy of acute promyelocytic leukemia
    • Barbui T, Finazzi G & Falanga A. The impact of all-trans retinoic acid on the coagulopathy of acute promyelocytic leukemia. Blood 1998; 91: 3093-3102.
    • (1998) Blood , vol.91 , pp. 3093-3102
    • Barbui, T.1    Finazzi, G.2    Falanga, A.3
  • 9
    • 0034124641 scopus 로고    scopus 로고
    • Early haemorrhagic morbidity and mortality during remission induction with or without all-trans retinoic acid in acute promyelocytic leukaemia
    • Di Bona E, Avvisati G, Castaman G et al. Early haemorrhagic morbidity and mortality during remission induction with or without all-trans retinoic acid in acute promyelocytic leukaemia. British Journal of Haematology 2000; 108: 689-695.
    • (2000) British Journal of Haematology , vol.108 , pp. 689-695
    • Di Bona, E.1    Avvisati, G.2    Castaman, G.3
  • 12
    • 0020053354 scopus 로고
    • Acute promyelocytic leukaemia; a study of 39 cases with identification of a hyperbasofilic microgranular variant
    • Mc Kenna RW, Parkin J, Bloomfield CD et al. Acute promyelocytic leukaemia; a study of 39 cases with identification of a hyperbasofilic microgranular variant. British Journal of Haematology 1982; 50: 201-214.
    • (1982) British Journal of Haematology , vol.50 , pp. 201-214
    • Mc Kenna, R.W.1    Parkin, J.2    Bloomfield, C.D.3
  • 13
    • 0027159683 scopus 로고
    • Basophilic differentiation in acute promyelocytic leukemia
    • Tallman MS, Hakimian D, Snower D et al. Basophilic differentiation in acute promyelocytic leukemia. Leukemia 1993; 7: 521-526.
    • (1993) Leukemia , vol.7 , pp. 521-526
    • Tallman, M.S.1    Hakimian, D.2    Snower, D.3
  • 14
    • 0344336086 scopus 로고    scopus 로고
    • Immunophenotype of adult and childhood acute promyelocytic leukaemia: Correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases
    • Guglielmi C, Martelli MP, Diverio D et al. Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases. British Journal of Haematology 1998; 102: 1035-1041.
    • (1998) British Journal of Haematology , vol.102 , pp. 1035-1041
    • Guglielmi, C.1    Martelli, M.P.2    Diverio, D.3
  • 15
    • 0034061846 scopus 로고    scopus 로고
    • CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous ATRA and chemotherapy
    • Ferrara F, Morabito F, Martino B et al. CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous ATRA and chemotherapy. Journal of Clinical Oncology 2000; 18: 1295-1300.
    • (2000) Journal of Clinical Oncology , vol.18 , pp. 1295-1300
    • Ferrara, F.1    Morabito, F.2    Martino, B.3
  • 16
    • 0032923932 scopus 로고    scopus 로고
    • CD56 expression in acute promyelocytic leukemia: A possible indicator of poor treatment outcome?
    • Murray CK, Estey E, Paietta E et al. CD56 expression in acute promyelocytic leukemia: a possible indicator of poor treatment outcome? Journal of Clinical Oncology 1999; 17: 293-297.
    • (1999) Journal of Clinical Oncology , vol.17 , pp. 293-297
    • Murray, C.K.1    Estey, E.2    Paietta, E.3
  • 17
    • 9444225115 scopus 로고    scopus 로고
    • Establishing the presence of the t(l5;17) in suspected acute promyelocytic leukaemia (APL): Cytogenetic, molecular and PML-immunofluorescence assessment of patients entered into the MRC ATRA trial
    • Grimwade D, Howe K, Langabeer S et al. Establishing the presence of the t(15;17) in suspected acute promyelocytic leukaemia (APL): cytogenetic, molecular and PML-immunofluorescence assessment of patients entered into the MRC ATRA trial. British Journal of Haematology 1996; 94: 557-573.
    • (1996) British Journal of Haematology , vol.94 , pp. 557-573
    • Grimwade, D.1    Howe, K.2    Langabeer, S.3
  • 18
    • 0033564337 scopus 로고    scopus 로고
    • Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: Results of the randomized MRC trial
    • Burnett AK, Grimwade D, Solomon E et al. Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: results of the randomized MRC trial. Blood 1999; 93: 4131-4134.
    • (1999) Blood , vol.93 , pp. 4131-4134
    • Burnett, A.K.1    Grimwade, D.2    Solomon, E.3
  • 19
    • 0034663029 scopus 로고    scopus 로고
    • Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): Results of the European Working Party
    • Grimwade D, Biondi A, Mozziconacci M-J et al. Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party. Blood 2000; 96: 1297-1308.
    • (2000) Blood , vol.96 , pp. 1297-1308
    • Grimwade, D.1    Biondi, A.2    Mozziconacci, M.-J.3
  • 20
    • 0029097216 scopus 로고
    • Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML-RARα protein
    • Dyck J, Warrell RP, Evans RM et al. Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML-RARα protein. Blood 1995; 86: 862-867.
    • (1995) Blood , vol.86 , pp. 862-867
    • Dyck, J.1    Warrell, R.P.2    Evans, R.M.3
  • 21
    • 0030733063 scopus 로고    scopus 로고
    • Immunocytochemical diagnosis of acute promyelocytic leukemia (M3) with the monoclonal antibody PG-M3
    • Falini B, Flenghi L, Fagioli M et al. Immunocytochemical diagnosis of acute promyelocytic leukemia (M3) with the monoclonal antibody PG-M3. Blood 1997; 90: 4046-4053.
    • (1997) Blood , vol.90 , pp. 4046-4053
    • Falini, B.1    Flenghi, L.2    Fagioli, M.3
  • 22
    • 0033168322 scopus 로고    scopus 로고
    • Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia
    • Lo Coco F, Diverio D, Falini B et al. Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia. Blood 1999; 94: 12-22.
    • (1999) Blood , vol.94 , pp. 12-22
    • Lo Coco, F.1    Diverio, D.2    Falini, B.3
  • 23
    • 0032853710 scopus 로고    scopus 로고
    • The pathogenesis of acute promyelocytic leukaemia: Evaluation of the role of molecular diagnosis and monitoring in the management of the disease
    • Grimwade D. The pathogenesis of acute promyelocytic leukaemia: evaluation of the role of molecular diagnosis and monitoring in the management of the disease. British Journal of Haematology 1999; 106: 591-613.
    • (1999) British Journal of Haematology , vol.106 , pp. 591-613
    • Grimwade, D.1
  • 24
    • 0030015860 scopus 로고    scopus 로고
    • Improved rapid detection of the PML-RARα fusion gene in acute promyelocytic leukemia
    • Diverio D, Riccioni R, Pistilli A et al. Improved rapid detection of the PML-RARα fusion gene in acute promyelocytic leukemia. Leukemia 1996; 10: 1214-1216.
    • (1996) Leukemia , vol.10 , pp. 1214-1216
    • Diverio, D.1    Riccioni, R.2    Pistilli, A.3
  • 25
    • 0033975927 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR
    • Cassinat B, Zassadowski F, Balitrand N et al. Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR. Leukemia 2000; 14: 324-328.
    • (2000) Leukemia , vol.14 , pp. 324-328
    • Cassinat, B.1    Zassadowski, F.2    Balitrand, N.3
  • 27
    • 0026513504 scopus 로고
    • Genomic variability and alternative splicing generate multiple PML-RARα transcripts that encode aberrant PML proteins and PML-RARα isoforms in acute promyelocytic leukemia
    • Pandolfi PP, Alcalay A, Fagioli M et al. Genomic variability and alternative splicing generate multiple PML-RARα transcripts that encode aberrant PML proteins and PML-RARα isoforms in acute promyelocytic leukemia. EMBO Journal 1992; 11: 1397-1407.
    • (1992) EMBO Journal , vol.11 , pp. 1397-1407
    • Pandolfi, P.P.1    Alcalay, A.2    Fagioli, M.3
  • 28
    • 0032867588 scopus 로고    scopus 로고
    • The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor α in acute promyelocytic-like leukaemia
    • Arnould C, Philippe C, Bourdon V et al. The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor α in acute promyelocytic-like leukaemia. Human Molecular Genetics 1999; 8: 1741-1749.
    • (1999) Human Molecular Genetics , vol.8 , pp. 1741-1749
    • Arnould, C.1    Philippe, C.2    Bourdon, V.3
  • 29
    • 0027258363 scopus 로고
    • Rearrangements of the retinoic acid receptor α and promyelocytic zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia
    • Zelent S-J, Tong J-H et al. Rearrangements of the retinoic acid receptor α and promyelocytic zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia. Journal of Clinical Investigation 1993; 91: 2260-2267.
    • (1993) Journal of Clinical Investigation , vol.91 , pp. 2260-2267
    • Zelent, S.-J.1    Tong, J.-H.2
  • 30
    • 0027411688 scopus 로고
    • Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-α locus due to a variant t(11;17) translocation associated with acute promyelocytic leukemia
    • Chen Z, Brand NJ, Chen A et al. Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-α locus due to a variant t(11;17) translocation associated with acute promyelocytic leukemia. EMBO Journal 1993; 12: 1161-1167.
    • (1993) EMBO Journal , vol.12 , pp. 1161-1167
    • Chen, Z.1    Brand, N.J.2    Chen, A.3
  • 31
    • 0030022316 scopus 로고    scopus 로고
    • The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
    • Redner RL, Rush EA, Faas S et al. The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood 1996; 87: 882-886.
    • (1996) Blood , vol.87 , pp. 882-886
    • Redner, R.L.1    Rush, E.A.2    Faas, S.3
  • 32
    • 0030771192 scopus 로고    scopus 로고
    • Fusion of retinoic acid receptor α to NUMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia
    • Wells RA, Catzavelos C & Kamel-Reid S. Fusion of retinoic acid receptor α to NUMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia. Nature Genetics 1997; 17: 109-113.
    • (1997) Nature Genetics , vol.17 , pp. 109-113
    • Wells, R.A.1    Catzavelos, C.2    Kamel-Reid, S.3
  • 33
    • 0028899552 scopus 로고
    • Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11; 17)
    • Licht JD, Chomienne C, Goy A et al. Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11; 17). Blood 1995; 85: 1083-1094.
    • (1995) Blood , vol.85 , pp. 1083-1094
    • Licht, J.D.1    Chomienne, C.2    Goy, A.3
  • 34
    • 0033611572 scopus 로고    scopus 로고
    • Retinoic acid, but not arsenic trioxide, degrades the PLZF/RAR(fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17) (q23;q21) APL patient
    • Koken MH, Daniel MT, Gianni M et al. Retinoic acid, but not arsenic trioxide, degrades the PLZF/RAR(fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17) (q23;q21) APL patient. Oncogene 1999; 18: 1113-1118.
    • (1999) Oncogene , vol.18 , pp. 1113-1118
    • Koken, M.H.1    Daniel, M.T.2    Gianni, M.3
  • 35
    • 0027937940 scopus 로고
    • Early mortality and retinoic acid syndrome in acute promyelocytic leukemia: Impact of leucocytosis, low-dose chemotherapy, PML/RARα isoform, and CD13 expression in patients treated with all-trans retinoic acid
    • Vahdat L, Maslak P, Miller WH et al. Early mortality and retinoic acid syndrome in acute promyelocytic leukemia: Impact of leucocytosis, low-dose chemotherapy, PML/RARα isoform, and CD13 expression in patients treated with all-trans retinoic acid. Blood 1994; 84: 3843-3849.
    • (1994) Blood , vol.84 , pp. 3843-3849
    • Vahdat, L.1    Maslak, P.2    Miller, W.H.3
  • 36
    • 0029162610 scopus 로고
    • Characterization of acute promyelocytic leukemia cases with PML/RARα break/fusion sites in PML exon 6: Identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid
    • Gallagher RE, Li Y-P, Rao S et al. Characterization of acute promyelocytic leukemia cases with PML/RARα break/fusion sites in PML exon 6: Identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid. Blood 1995; 86: 1540-1547.
    • (1995) Blood , vol.86 , pp. 1540-1547
    • Gallagher, R.E.1    Li, Y.-P.2    Rao, S.3
  • 37
    • 0029090552 scopus 로고
    • Isoforms of PML-retinoic acid receptor alpha fused transcripts affect neither clinical features of acute promyelocytic leukemia nor prognosis after treatment with all-trans retinoic acid
    • Fukutani H, Naoe T, Ohno R et al. Isoforms of PML-retinoic acid receptor alpha fused transcripts affect neither clinical features of acute promyelocytic leukemia nor prognosis after treatment with all-trans retinoic acid. Leukemia 1995; 9: 1478-1482.
    • (1995) Leukemia , vol.9 , pp. 1478-1482
    • Fukutani, H.1    Naoe, T.2    Ohno, R.3
  • 38
    • 0030812198 scopus 로고    scopus 로고
    • Association of PML/RARα fusion mRNA type with pre-treatment characteristics but not treatment outcome in acute promyelocytic leukemia: An intergroup molecular study
    • Gallagher RE, Willman CL, Slack JL et al. Association of PML/RARα fusion mRNA type with pre-treatment characteristics but not treatment outcome in acute promyelocytic leukemia: an intergroup molecular study. Blood 1997; 90: 1656-1663.
    • (1997) Blood , vol.90 , pp. 1656-1663
    • Gallagher, R.E.1    Willman, C.L.2    Slack, J.L.3
  • 39
    • 0034650973 scopus 로고    scopus 로고
    • Molecular analysis and clinical outcome of adult APL patients with the V PML/RARα isoform: Results from Intergroup protocol 0129
    • Slack JL, Willman CL, Andersen JW et al. Molecular analysis and clinical outcome of adult APL patients with the V PML/RARα isoform: results from Intergroup protocol 0129. Blood 2000; 95: 398-403.
    • (2000) Blood , vol.95 , pp. 398-403
    • Slack, J.L.1    Willman, C.L.2    Andersen, J.W.3
  • 40
    • 0034935027 scopus 로고    scopus 로고
    • Pretreatment characteristics and clinical outcome of acute promyelocytic leukaemia patients according to the PML-RAR alpha isoforms: A study of the PETHEMA group
    • Gonzalez M, Barragan E, Bolufer P et al. Pretreatment characteristics and clinical outcome of acute promyelocytic leukaemia patients according to the PML-RAR alpha isoforms: a study of the PETHEMA group. British Journal of Haematology 2001; 114: 99- 103.
    • (2001) British Journal of Haematology , vol.114 , pp. 99-103
    • Gonzalez, M.1    Barragan, E.2    Bolufer, P.3
  • 41
    • 0029817444 scopus 로고    scopus 로고
    • Quantification of PML/RARa transcript in acute promyelocytic leukaemia: Explanation for lack of sensitivity of RT-PCR for the detection of minimal residual disease and induction of the leukaemia specific mRNA by alpha interferon
    • Seale JRC, Varma S, Swirsky DM et al. Quantification of PML/RARa transcript in acute promyelocytic leukaemia: explanation for lack of sensitivity of RT-PCR for the detection of minimal residual disease and induction of the leukaemia specific mRNA by alpha interferon. British Journal of Haemotology 1996; 95: 95-101.
    • (1996) British Journal of Haemotology , vol.95 , pp. 95-101
    • Seale, J.R.C.1    Varma, S.2    Swirsky, D.M.3
  • 42
    • 0031961755 scopus 로고    scopus 로고
    • Analysis of prognostic factors in newly diagnosed acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy
    • Japan Adult Leukemia Study Group
    • Asou N, Adachi K, Tamura J et al. Analysis of prognostic factors in newly diagnosed acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. Japan Adult Leukemia Study Group. Journal of Clinical Oncology 1998; 16: 78-85.
    • (1998) Journal of Clinical Oncology , vol.16 , pp. 78-85
    • Asou, N.1    Adachi, K.2    Tamura, J.3
  • 43
    • 0033566639 scopus 로고    scopus 로고
    • A randomized comparison of ATRA followed by chemotherapy and ATRA plus chemotherapy, and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia
    • Fenaux P, Chastang C, Chevret S et al. A randomized comparison of ATRA followed by chemotherapy and ATRA plus chemotherapy, and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. Blood 1999; 94: 1192-1200.
    • (1999) Blood , vol.94 , pp. 1192-1200
    • Fenaux, P.1    Chastang, C.2    Chevret, S.3
  • 44
    • 0030825408 scopus 로고    scopus 로고
    • Molecular remission in PML/RARa positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy
    • Mandelli F, Diverio D, Avvisati G et al. Molecular remission in PML/RARa positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy. Blood 1997; 90: 1014-1021.
    • (1997) Blood , vol.90 , pp. 1014-1021
    • Mandelli, F.1    Diverio, D.2    Avvisati, G.3
  • 45
    • 0033230342 scopus 로고    scopus 로고
    • A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARa positive acute promyelocytic leukemia
    • Sanz MA, Martin G, Rayon C et al. A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARa positive acute promyelocytic leukemia. Blood 1999; 94: 3015-3021.
    • (1999) Blood , vol.94 , pp. 3015-3021
    • Sanz, M.A.1    Martin, G.2    Rayon, C.3
  • 46
    • 0034663162 scopus 로고    scopus 로고
    • Definition of relapse risk and role of non-anthracycline drugs for consolidation in patients with acute promyelocytic leukemia: A joint study of the PETHEMA and GIMEMA cooperative groups
    • Sanz MA, Lo Coco F, Martín G et al. Definition of relapse risk and role of non-anthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups. Blood 2000; 96: 1247-1253.
    • (2000) Blood , vol.96 , pp. 1247-1253
    • Sanz, M.A.1    Lo Coco, F.2    Martín, G.3
  • 47
    • 0033858433 scopus 로고    scopus 로고
    • Double induction strategy including high dose cytarabine in combination with all-trans retinoic acid: Effects in patients with newly diagnosed acute promyelocytic leukemia. German AML Cooperative Group
    • Lengfelder E, Reichert A, Schoch C et al. Double induction strategy including high dose cytarabine in combination with all-trans retinoic acid: effects in patients with newly diagnosed acute promyelocytic leukemia. German AML Cooperative Group. Leukemia 2000; 14: 1362-1370.
    • (2000) Leukemia , vol.14 , pp. 1362-1370
    • Lengfelder, E.1    Reichert, A.2    Schoch, C.3
  • 48
    • 0037115195 scopus 로고    scopus 로고
    • All-trans retinoic acid in acute promyelocytic leukemia: Long-term outcome and prognostic factor analysis from the North American Intergroup protocol
    • Tallman MS, Andersen JW, Schiffer CA et al. All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol. Blood 2002; 100: 4298-4302.
    • (2002) Blood , vol.100 , pp. 4298-4302
    • Tallman, M.S.1    Andersen, J.W.2    Schiffer, C.A.3
  • 49
    • 0001245199 scopus 로고    scopus 로고
    • Detection of minimal residual disease (MRD) in APL by real-time RT-PCR: Analysis of cases entered into the UK MRC ATRA trial
    • Grimwade D, Diverio D, Harrison G et al. Detection of minimal residual disease (MRD) in APL by real-time RT-PCR: analysis of cases entered into the UK MRC ATRA trial. Blood 1999; 94(supplement 1): 625a.
    • (1999) Blood , vol.94 , Issue.SUPPL. 1
    • Grimwade, D.1    Diverio, D.2    Harrison, G.3
  • 50
    • 0030061520 scopus 로고    scopus 로고
    • Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: Evaluation of PML-RAR alpha and RAR alpha-PML assessment in patients who ultimately relapse
    • Grimwade D, Howe K, Langabeer S et al. Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: evaluation of PML-RAR alpha and RAR alpha-PML assessment in patients who ultimately relapse. Leukemia 1996; 10: 61-66.
    • (1996) Leukemia , vol.10 , pp. 61-66
    • Grimwade, D.1    Howe, K.2    Langabeer, S.3
  • 51
    • 0028980278 scopus 로고
    • Persistence of RAR alpha-PML fusion mRNA detected by reverse transcriptase polymerase chain reaction in patients in long-term remission of acute promyelocytic leukaemia
    • Tobal K, Saunders MJ, Grey MR & Yin JA. Persistence of RAR alpha-PML fusion mRNA detected by reverse transcriptase polymerase chain reaction in patients in long-term remission of acute promyelocytic leukaemia. British Journal of Haematology 1995; 90: 615-618.
    • (1995) British Journal of Haematology , vol.90 , pp. 615-618
    • Tobal, K.1    Saunders, M.J.2    Grey, M.R.3    Yin, J.A.4
  • 52
    • 0031708687 scopus 로고    scopus 로고
    • RT-PCR method with increased sensitivity shows persistence of PML-RARA fusion transcripts in patients in long-term remission of APL
    • Tobal K, Liu Yin JA et al. RT-PCR method with increased sensitivity shows persistence of PML-RARA fusion transcripts in patients in long-term remission of APL. Leukemia 1998; 12: 1349-1354.
    • (1998) Leukemia , vol.12 , pp. 1349-1354
    • Tobal, K.1    Liu Yin, J.A.2
  • 53
    • 0036009618 scopus 로고    scopus 로고
    • The significance of minimal residual disease in patients with t(15;17)
    • Grimwade D. The significance of minimal residual disease in patients with t(15;17). Baillière's Clinical Haematology 2002; 15: 137-158.
    • (2002) Baillière's Clinical Haematology , vol.15 , pp. 137-158
    • Grimwade, D.1
  • 54
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of real-time quantitative reverse transcriptase polymerase chain reaction (RQ-PCR) of fusion gene transcripts for residual disease detection in leukemia - A Europe Against Cancer Program
    • in press
    • Gabert J, Beillard E, van der Velden VHJ et al. Standardization and quality control studies of real-time quantitative reverse transcriptase polymerase chain reaction (RQ-PCR) of fusion gene transcripts for residual disease detection in leukemia - A Europe Against Cancer Program. Leukemia 2003;. in press.
    • (2003) Leukemia
    • Gabert, J.1    Beillard, E.2    van der Velden, V.H.J.3
  • 55
    • 0038446666 scopus 로고    scopus 로고
    • Quantitative real time RT-PCR analysis of PML/RARa mRNA in acute promyelocytic leukemia: Assessment of prognostic significance in adult patients from intergroup protocol 0129
    • Gallagher RE, Yeap BY, Wanli BI et al. Quantitative real time RT-PCR analysis of PML/RARa mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129. Blood 2003; 101: 2521-2528.
    • (2003) Blood , vol.101 , pp. 2521-2528
    • Gallagher, R.E.1    Yeap, B.Y.2    Wanli, B.I.3
  • 56
    • 0026559655 scopus 로고
    • Reverse transription polymerase chain reaction for the rearrenged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia
    • Miller WH, Kakizuka A, Frankel SR et al. Reverse transription polymerase chain reaction for the rearrenged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the USA 1992; 89: 2694-2698.
    • (1992) Proceedings of the National Academy of Sciences of the USA , vol.89 , pp. 2694-2698
    • Miller, W.H.1    Kakizuka, A.2    Frankel, S.R.3
  • 57
    • 0026645140 scopus 로고
    • Molecular monitoring of the myl/retinoic acid receptor-α fusion gene in acute promyelocytic leukemia by polymerase chain reaction
    • Biondi A, Rambaldi A, Pandolfi PP et al. Molecular monitoring of the myl/retinoic acid receptor-α fusion gene in acute promyelocytic leukemia by polymerase chain reaction. Blood 1992; 80: 492-497.
    • (1992) Blood , vol.80 , pp. 492-497
    • Biondi, A.1    Rambaldi, A.2    Pandolfi, P.P.3
  • 58
    • 0026652137 scopus 로고
    • A PML/retinoic acid receptor a fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia
    • Castaigne S, Balitrand N, de Thè H et al. A PML/retinoic acid receptor a fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia. Blood 1992; 79: 3110-3115.
    • (1992) Blood , vol.79 , pp. 3110-3115
    • Castaigne, S.1    Balitrand, N.2    de Thè, H.3
  • 59
    • 0026595709 scopus 로고
    • The (15;17) breakpoint in acute promyelocytic leukemia cluster within two different sites of the myl gene. Targets for the detection of minimal residual disease by PCR
    • Chang KS, Lu J, Wang G et al. The (15;17) breakpoint in acute promyelocytic leukemia cluster within two different sites of the myl gene. Targets for the detection of minimal residual disease by PCR. Blood 1992; 79: 554-558.
    • (1992) Blood , vol.79 , pp. 554-558
    • Chang, K.S.1    Lu, J.2    Wang, G.3
  • 60
    • 0026446190 scopus 로고
    • Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia
    • Lo Coco F, Diverio D, Pandolfi PP et al. Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia. Lancet 1992; 340: 1437-1438.
    • (1992) Lancet , vol.340 , pp. 1437-1438
    • Lo Coco, F.1    Diverio, D.2    Pandolfi, P.P.3
  • 61
    • 0027237223 scopus 로고
    • Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA
    • Miller WH, Levine K, DeBlasio A et al. Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA. Blood 1993; 82: 1689-1694.
    • (1993) Blood , vol.82 , pp. 1689-1694
    • Miller, W.H.1    Levine, K.2    DeBlasio, A.3
  • 62
    • 12444294284 scopus 로고
    • Absence of RT-PCR detectable residual disease in acute promyelocytic leukemia in long term remission
    • Diverio D, Pandolfi PP, Biondi A et al. Absence of RT-PCR detectable residual disease in acute promyelocytic leukemia in long term remission. Blood 1993; 82: 1689-1694.
    • (1993) Blood , vol.82 , pp. 1689-1694
    • Diverio, D.1    Pandolfi, P.P.2    Biondi, A.3
  • 63
    • 0028908197 scopus 로고
    • Prognostic significance of the RT-PCR assay of PML/RARa transcripts in acute promyelocytic leukemia
    • Fukutani H, Naoe T, Ohno R et al. Prognostic significance of the RT-PCR assay of PML/RARa transcripts in acute promyelocytic leukemia. Leukemia 1995; 9: 588-593.
    • (1995) Leukemia , vol.9 , pp. 588-593
    • Fukutani, H.1    Naoe, T.2    Ohno, R.3
  • 64
    • 0029007318 scopus 로고
    • Detection of minimal residual disease by reverse transcriptase polymerase chain reaction for the PML/RARa fusion mRNA: A study in patients with acute promyelocytic leukemia following peripheral stem cell transplantation
    • Takatsuki H, Umemura T, Sadamura S et al. Detection of minimal residual disease by reverse transcriptase polymerase chain reaction for the PML/RARa fusion mRNA: a study in patients with acute promyelocytic leukemia following peripheral stem cell transplantation. Leukemia 1995; 9: 889-892.
    • (1995) Leukemia , vol.9 , pp. 889-892
    • Takatsuki, H.1    Umemura, T.2    Sadamura, S.3
  • 65
    • 0030980533 scopus 로고    scopus 로고
    • Absence of detectable PML-RARα fusion transcripts in long-term remission patients after BMT for acute promyelocytic leukemia
    • Román J, Martín C, Torres A et al. Absence of detectable PML-RARα fusion transcripts in long-term remission patients after BMT for acute promyelocytic leukemia. Bone Marrow Transplantation 1997; 19: 679-683.
    • (1997) Bone Marrow Transplantation , vol.19 , pp. 679-683
    • Román, J.1    Martín, C.2    Torres, A.3
  • 66
    • 0032147033 scopus 로고    scopus 로고
    • Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARα fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter AIDA trial
    • Diverio D, Rossi V, Avvisati G et al. Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARα fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter AIDA trial. Blood 1998; 92: 784-789.
    • (1998) Blood , vol.92 , pp. 784-789
    • Diverio, D.1    Rossi, V.2    Avvisati, G.3
  • 67
    • 0039923333 scopus 로고    scopus 로고
    • Monitoring of minimal residual disease with the combined detection of PML/RAR alpha and RAR alpha/PML rearrangements in acute promyelocytic leukemia
    • Bolufer P, Barragán E, Sanz MA et al. Monitoring of minimal residual disease with the combined detection of PML/RAR alpha and RAR alpha/PML rearrangements in acute promyelocytic leukemia. Medicina Clinica (Barcelona) 2000; 114: 281-285.
    • (2000) Medicina Clinica (Barcelona) , vol.114 , pp. 281-285
    • Bolufer, P.1    Barragán, E.2    Sanz, M.A.3
  • 68
    • 0034962192 scopus 로고    scopus 로고
    • The PML-RARα transcript in long-term follow-up of acute promyelocytic leukaemia patients
    • Gameiro P, Vieira S, Silva CP et al. The PML-RARα transcript in long-term follow-up of acute promyelocytic leukaemia patients. Haematologica 2001; 86: 577-585.
    • (2001) Haematologica , vol.86 , pp. 577-585
    • Gameiro, P.1    Vieira, S.2    Silva, C.P.3
  • 69
    • 0035525767 scopus 로고    scopus 로고
    • Prognostic significance of minimal residual disease detection and PML/RARα isoform type: Long term follow-up in acute promyelocytic leukemia
    • Jurcic JG, Nimer SD, Scheinberg DA et al. Prognostic significance of minimal residual disease detection and PML/RARα isoform type: long term follow-up in acute promyelocytic leukemia. Blood 2001; 98: 2651-2656.
    • (2001) Blood , vol.98 , pp. 2651-2656
    • Jurcic, J.G.1    Nimer, S.D.2    Scheinberg, D.A.3
  • 70
    • 0033214651 scopus 로고    scopus 로고
    • Therapy of molecular relapse in acute promyelocytic leukemia
    • Lo Coco F, Diverio D, Avvisati G et al. Therapy of molecular relapse in acute promyelocytic leukemia. Blood 1999; 94: 2225-2229.
    • (1999) Blood , vol.94 , pp. 2225-2229
    • Lo Coco, F.1    Diverio, D.2    Avvisati, G.3
  • 71
    • 0030610687 scopus 로고    scopus 로고
    • 3) in the treatment of acute promyelocytic leukemia (APL). II Clinical efficacy and pharmacokinetics in relapsed patients
    • 3) in the treatment of acute promyelocytic leukemia (APL). II Clinical efficacy and pharmacokinetics in relapsed patients. Blood 1997; 89: 3354-3360.
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Z.X.1    Chen, C.Q.2    Ni, J.H.3
  • 72
    • 0032487923 scopus 로고    scopus 로고
    • Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
    • Soignet SL, Maslack P, Wang ZG et al. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. New England Journal of Medicine 1998; 339: 1341-1348.
    • (1998) New England Journal of Medicine , vol.339 , pp. 1341-1348
    • Soignet, S.L.1    Maslack, P.2    Wang, Z.G.3
  • 73
    • 0033570955 scopus 로고    scopus 로고
    • Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: Remission induction, follow-up and molecular monitoring in II newly diagnosed and 47 relapsed acute promyelocytic leukemia patients
    • Niu C, Yan H, Yu T et al. Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up and molecular monitoring in II newly diagnosed and 47 relapsed acute promyelocytic leukemia patients. Blood 1999; 94: 3315-3324.
    • (1999) Blood , vol.94 , pp. 3315-3324
    • Niu, C.1    Yan, H.2    Yu, T.3
  • 74
    • 0035884639 scopus 로고    scopus 로고
    • United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia
    • Soignet SL, Frankel SR, Douer D et al. United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia. Journal of Clinical Oncology 2001; 19: 3852-3860.
    • (2001) Journal of Clinical Oncology , vol.19 , pp. 3852-3860
    • Soignet, S.L.1    Frankel, S.R.2    Douer, D.3
  • 75
    • 0030741745 scopus 로고    scopus 로고
    • Autologous bone marrow transplantation for acute promyelocytic leukemia in second remission: Prognostic relevance of pretransplant minimal residual disease assessment by reverse-transcription polymerase chain reaction of the PML/RARa fusion gene
    • Meloni G, Diverio D, Vignetti M et al. Autologous bone marrow transplantation for acute promyelocytic leukemia in second remission: prognostic relevance of pretransplant minimal residual disease assessment by reverse-transcription polymerase chain reaction of the PML/RARa fusion gene. Blood 1997; 90: 1321-1325.
    • (1997) Blood , vol.90 , pp. 1321-1325
    • Meloni, G.1    Diverio, D.2    Vignetti, M.3
  • 76
    • 0034046084 scopus 로고    scopus 로고
    • Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid followed by timed sequential chemotherapy and stem cell transplantation
    • Thomas X, Dombret H, Cordonnier C et al. Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid followed by timed sequential chemotherapy and stem cell transplantation. Leukemia 2000; 14: 1006-1013.
    • (2000) Leukemia , vol.14 , pp. 1006-1013
    • Thomas, X.1    Dombret, H.2    Cordonnier, C.3
  • 77
    • 0033215452 scopus 로고    scopus 로고
    • Molecular remission induced by liposomal-encapsulated all-trans-retinoic acid in newly diagnosed acute promyelocytic leukaemia
    • Estey E, Giles FJ, Kantarjian H et al. Molecular remission induced by liposomal-encapsulated all-trans-retinoic acid in newly diagnosed acute promyelocytic leukaemia. Blood 1999; 94: 2230-2235.
    • (1999) Blood , vol.94 , pp. 2230-2235
    • Estey, E.1    Giles, F.J.2    Kantarjian, H.3
  • 78
    • 0035169587 scopus 로고    scopus 로고
    • Treatment of newly diagnosed and relapsed acute promyelocytic leukemia with intravenous liposomal all-trans retinoic acid
    • Douer D, Estey E, Santillana S et al. Treatment of newly diagnosed and relapsed acute promyelocytic leukemia with intravenous liposomal all-trans retinoic acid. Blood 2001; 97: 73-80.
    • (2001) Blood , vol.97 , pp. 73-80
    • Douer, D.1    Estey, E.2    Santillana, S.3
  • 79
    • 0035115221 scopus 로고    scopus 로고
    • Antibody therapy for residual disease in acute myelogenous leukemia
    • Jurcic JG. Antibody therapy for residual disease in acute myelogenous leukemia. Clinical Review in Oncology and Hematology 2001; 38: 37-45.
    • (2001) Clinical Review in Oncology and Hematology , vol.38 , pp. 37-45
    • Jurcic, J.G.1
  • 80
    • 0034773130 scopus 로고    scopus 로고
    • Prolonged molecular remission in advanced acute promyelocytic leukaemia after treatment with gemtuzumab ozogamicin
    • Petti MC, Pinazzi B, Diverto D et al. Prolonged molecular remission in advanced acute promyelocytic leukaemia after treatment with gemtuzumab ozogamicin. British Journal of Haematology 2001; 115:63-65.
    • (2001) British Journal of Haematology , vol.115 , pp. 63-65
    • Petti, M.C.1    Pinazzi, B.2    Diverto, D.3
  • 81
    • 0036625070 scopus 로고    scopus 로고
    • Experience with gemtuzumab ozogamycin (mylotarg) and all-trans retinoic acid in untreated acute promyelocytic leukemia
    • Estey EH, Giles FJ, Beran M et al. Experience with gemtuzumab ozogamycin (mylotarg) and all-trans retinoic acid in untreated acute promyelocytic leukemia. Blood 2002; 99: 4222-4224.
    • (2002) Blood , vol.99 , pp. 4222-4224
    • Estey, E.H.1    Giles, F.J.2    Beran, M.3
  • 82
    • 0012916663 scopus 로고    scopus 로고
    • All-trans retinoic acid and anthracycline reinforcement in consolidation improve the outcome of patients with intermediate and high-risk acute promyelocytic leukemia: Results of the Spanish PETHEMA trial LPA99
    • Sanz MA, Martin G, Barragán E et al. All-trans retinoic acid and anthracycline reinforcement in consolidation improve the outcome of patients with intermediate and high-risk acute promyelocytic leukemia: results of the Spanish PETHEMA trial LPA99. Blood 2002; 100: 155a.
    • (2002) Blood , vol.100
    • Sanz, M.A.1    Martin, G.2    Barragán, E.3
  • 83
    • 0036464656 scopus 로고    scopus 로고
    • Therapy-related myelodysplastic syndrome-acute myelogenous leukemia in patients treated for acute promyelocytic leukemia: An emerging problem
    • Latagliata R, Petti MC, Fenu S et al. Therapy-related myelodysplastic syndrome-acute myelogenous leukemia in patients treated for acute promyelocytic leukemia: an emerging problem. Blood 2002; 99: 822-824.
    • (2002) Blood , vol.99 , pp. 822-824
    • Latagliata, R.1    Petti, M.C.2    Fenu, S.3
  • 85
    • 0003314771 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in acute promyelocytic leukemia (APL) by real time quantitative RT-PCR with specific fluorescent hybridization probes
    • Mitterbauer A, Mannhalter C, Jager U et al. Quantitation of minimal residual disease in acute promyelocytic leukemia (APL) by real time quantitative RT-PCR with specific fluorescent hybridization probes. Blood 2000; 94(supplement 1): 313a.
    • (2000) Blood , vol.94 , Issue.SUPPL. 1
    • Mitterbauer, A.1    Mannhalter, C.2    Jager, U.3


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