메뉴 건너뛰기




Volumn 8, Issue 4, 2013, Pages

Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1;

EID: 84876422491     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061716     Document Type: Article
Times cited : (30)

References (54)
  • 2
    • 58149461559 scopus 로고    scopus 로고
    • Epidemiology, pathology, and genetics of prostate cancer among African Americans compared with other ethnicities
    • Williams H, Powell IJ, (2009) Epidemiology, pathology, and genetics of prostate cancer among African Americans compared with other ethnicities. Methods Mol Biol 472: 439-453.
    • (2009) Methods Mol Biol , vol.472 , pp. 439-453
    • Williams, H.1    Powell, I.J.2
  • 3
    • 34548171468 scopus 로고    scopus 로고
    • The androgen receptor in prostate cancer: therapy target in search of an integrated diagnostic test
    • Ross JS, (2007) The androgen receptor in prostate cancer: therapy target in search of an integrated diagnostic test. Adv Anat Pathol 14: 353-357.
    • (2007) Adv Anat Pathol , vol.14 , pp. 353-357
    • Ross, J.S.1
  • 4
    • 45049086542 scopus 로고    scopus 로고
    • Current status of experimental therapeutics for prostate cancer
    • Moon C, Park JC, Chae YK, Yun JH, Kim S, (2008) Current status of experimental therapeutics for prostate cancer. Cancer Lett 266: 116-134.
    • (2008) Cancer Lett , vol.266 , pp. 116-134
    • Moon, C.1    Park, J.C.2    Chae, Y.K.3    Yun, J.H.4    Kim, S.5
  • 5
    • 33846259375 scopus 로고    scopus 로고
    • Prostate cancer stem/progenitor cells: identification, characterization, and implications
    • Tang DG, Patrawala L, Calhoun T, Bhatia B, Choy G, et al. (2007) Prostate cancer stem/progenitor cells: identification, characterization, and implications. Mol Carcinog 46: 1-14.
    • (2007) Mol Carcinog , vol.46 , pp. 1-14
    • Tang, D.G.1    Patrawala, L.2    Calhoun, T.3    Bhatia, B.4    Choy, G.5
  • 6
    • 34547673401 scopus 로고    scopus 로고
    • Stem cells in prostate cancer initiation and progression
    • Lawson DA, Witte ON, (2007) Stem cells in prostate cancer initiation and progression. J Clin Invest 117: 2044-2050.
    • (2007) J Clin Invest , vol.117 , pp. 2044-2050
    • Lawson, D.A.1    Witte, O.N.2
  • 7
    • 46049102201 scopus 로고    scopus 로고
    • Stem cells: The root of prostate cancer
    • Kasper S, (2008) Stem cells: The root of prostate cancer? J Cell Physiol 216: 332-336.
    • (2008) J Cell Physiol , vol.216 , pp. 332-336
    • Kasper, S.1
  • 9
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, et al. (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65: 5506-5511.
    • (2005) Cancer Res , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3    Pratesi, G.4    Petrangolini, G.5
  • 10
    • 33846095137 scopus 로고    scopus 로고
    • Identification and expansion of human colon-cancer-initiating cells
    • Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, et al. (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115.
    • (2007) Nature , vol.445 , pp. 111-115
    • Ricci-Vitiani, L.1    Lombardi, D.G.2    Pilozzi, E.3    Biffoni, M.4    Todaro, M.5
  • 11
    • 79955660106 scopus 로고    scopus 로고
    • Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells
    • Rybak AP, He L, Kapoor A, Cutz JC, Tang D, (2011) Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells. Biochim Biophys Acta 1813: 683-694.
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 683-694
    • Rybak, A.P.1    He, L.2    Kapoor, A.3    Cutz, J.C.4    Tang, D.5
  • 12
    • 58549108859 scopus 로고    scopus 로고
    • The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
    • Dubrovska A, Kim S, Salamone RJ, Walker JR, Maira SM, et al. (2009) The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci U S A 106: 268-273.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 268-273
    • Dubrovska, A.1    Kim, S.2    Salamone, R.J.3    Walker, J.R.4    Maira, S.M.5
  • 13
    • 34248140257 scopus 로고    scopus 로고
    • Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens
    • Miki J, Furusato B, Li H, Gu Y, Takahashi H, et al. (2007) Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens. Cancer Res 67: 3153-3161.
    • (2007) Cancer Res , vol.67 , pp. 3153-3161
    • Miki, J.1    Furusato, B.2    Li, H.3    Gu, Y.4    Takahashi, H.5
  • 14
    • 36549019589 scopus 로고    scopus 로고
    • Telomerase-immortalized non-malignant human prostate epithelial cells retain the properties of multipotent stem cells
    • Li H, Zhou J, Miki J, Furusato B, Gu Y, et al. (2008) Telomerase-immortalized non-malignant human prostate epithelial cells retain the properties of multipotent stem cells. Exp Cell Res 314: 92-102.
    • (2008) Exp Cell Res , vol.314 , pp. 92-102
    • Li, H.1    Zhou, J.2    Miki, J.3    Furusato, B.4    Gu, Y.5
  • 15
    • 78751623400 scopus 로고    scopus 로고
    • Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-kappaB signalling
    • Rajasekhar VK, Studer L, Gerald W, Socci ND, Scher HI, (2011) Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-kappaB signalling. Nat Commun 2: 162.
    • (2011) Nat Commun , vol.2 , pp. 162
    • Rajasekhar, V.K.1    Studer, L.2    Gerald, W.3    Socci, N.D.4    Scher, H.I.5
  • 16
    • 84867415876 scopus 로고    scopus 로고
    • CD49f Is an Efficient Marker of Monolayer- and Spheroid Colony-Forming Cells of the Benign and Malignant Human Prostate
    • Yamamoto H, Masters JR, Dasgupta P, Chandra A, Popert R, et al. (2012) CD49f Is an Efficient Marker of Monolayer- and Spheroid Colony-Forming Cells of the Benign and Malignant Human Prostate. PLoS One 7: e46979.
    • (2012) PLoS One , vol.7
    • Yamamoto, H.1    Masters, J.R.2    Dasgupta, P.3    Chandra, A.4    Popert, R.5
  • 17
    • 84856645746 scopus 로고    scopus 로고
    • Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors
    • Salvatori L, Caporuscio F, Verdina A, Starace G, Crispi S, et al. (2012) Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors. PLoS One 7: e31467.
    • (2012) PLoS One , vol.7
    • Salvatori, L.1    Caporuscio, F.2    Verdina, A.3    Starace, G.4    Crispi, S.5
  • 18
    • 6044269168 scopus 로고    scopus 로고
    • ATM activity contributes to the tumor-suppressing functions of p14ARF
    • Li Y, Wu D, Chen B, Ingram A, He L, et al. (2004) ATM activity contributes to the tumor-suppressing functions of p14ARF. Oncogene 23: 7355-7365.
    • (2004) Oncogene , vol.23 , pp. 7355-7365
    • Li, Y.1    Wu, D.2    Chen, B.3    Ingram, A.4    He, L.5
  • 19
    • 9444273447 scopus 로고    scopus 로고
    • Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells
    • Chatterjee M, Stuhmer T, Herrmann P, Bommert K, Dorken B, et al. (2004) Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells. Blood 104: 3712-3721.
    • (2004) Blood , vol.104 , pp. 3712-3721
    • Chatterjee, M.1    Stuhmer, T.2    Herrmann, P.3    Bommert, K.4    Dorken, B.5
  • 20
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, et al. (1998) A third-generation lentivirus vector with a conditional packaging system. J Virol 72: 8463-8471.
    • (1998) J Virol , vol.72 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3    Mandel, R.J.4    Nguyen, M.5
  • 21
    • 69249139924 scopus 로고    scopus 로고
    • Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens
    • Kelly JJ, Stechishin O, Chojnacki A, Lun X, Sun B, et al. (2009) Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens. Stem Cells 27: 1722-1733.
    • (2009) Stem Cells , vol.27 , pp. 1722-1733
    • Kelly, J.J.1    Stechishin, O.2    Chojnacki, A.3    Lun, X.4    Sun, B.5
  • 22
    • 0029861248 scopus 로고    scopus 로고
    • Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor
    • Rojas M, Yao S, Lin YZ, (1996) Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor. J Biol Chem 271: 27456-27461.
    • (1996) J Biol Chem , vol.271 , pp. 27456-27461
    • Rojas, M.1    Yao, S.2    Lin, Y.Z.3
  • 23
    • 0028237507 scopus 로고
    • Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification
    • Ekstrand AJ, Longo N, Hamid ML, Olson JJ, Liu L, et al. (1994) Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification. Oncogene 9: 2313-2320.
    • (1994) Oncogene , vol.9 , pp. 2313-2320
    • Ekstrand, A.J.1    Longo, N.2    Hamid, M.L.3    Olson, J.J.4    Liu, L.5
  • 24
    • 34047273010 scopus 로고    scopus 로고
    • The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806
    • Gan HK, Walker F, Burgess AW, Rigopoulos A, Scott AM, et al. (2007) The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806. J Biol Chem 282: 2840-2850.
    • (2007) J Biol Chem , vol.282 , pp. 2840-2850
    • Gan, H.K.1    Walker, F.2    Burgess, A.W.3    Rigopoulos, A.4    Scott, A.M.5
  • 25
    • 13144266690 scopus 로고    scopus 로고
    • Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor
    • Fry DW, Bridges AJ, Denny WA, Doherty A, Greis KD, et al. (1998) Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A 95: 12022-12027.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 12022-12027
    • Fry, D.W.1    Bridges, A.J.2    Denny, W.A.3    Doherty, A.4    Greis, K.D.5
  • 26
    • 0023663092 scopus 로고
    • Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing
    • Honegger AM, Dull TJ, Felder S, Van Obberghen E, Bellot F, et al. (1987) Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing. Cell 51: 199-209.
    • (1987) Cell , vol.51 , pp. 199-209
    • Honegger, A.M.1    Dull, T.J.2    Felder, S.3    Van Obberghen, E.4    Bellot, F.5
  • 27
    • 0017883723 scopus 로고
    • Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells
    • Colburn NH, Bruegge WF, Bates JR, Gray RH, Rossen JD, et al. (1978) Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells. Cancer Res 38: 624-634.
    • (1978) Cancer Res , vol.38 , pp. 624-634
    • Colburn, N.H.1    Bruegge, W.F.2    Bates, J.R.3    Gray, R.H.4    Rossen, J.D.5
  • 28
    • 0006224409 scopus 로고
    • Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro
    • Shin SI, Freedman VH, Risser R, Pollack R, (1975) Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro. Proc Natl Acad Sci U S A 72: 4435-4439.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , pp. 4435-4439
    • Shin, S.I.1    Freedman, V.H.2    Risser, R.3    Pollack, R.4
  • 29
    • 0016318441 scopus 로고
    • Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium
    • Freedman VH, Shin SI, (1974) Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 3: 355-359.
    • (1974) Cell , vol.3 , pp. 355-359
    • Freedman, V.H.1    Shin, S.I.2
  • 30
    • 33748063941 scopus 로고    scopus 로고
    • Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
    • McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, et al. (2006) Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 46: 249-279.
    • (2006) Adv Enzyme Regul , vol.46 , pp. 249-279
    • McCubrey, J.A.1    Steelman, L.S.2    Abrams, S.L.3    Lee, J.T.4    Chang, F.5
  • 32
    • 0013689209 scopus 로고    scopus 로고
    • Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro
    • Grandis JR, Drenning SD, Chakraborty A, Zhou MY, Zeng Q, et al. (1998) Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro. J Clin Invest 102: 1385-1392.
    • (1998) J Clin Invest , vol.102 , pp. 1385-1392
    • Grandis, J.R.1    Drenning, S.D.2    Chakraborty, A.3    Zhou, M.Y.4    Zeng, Q.5
  • 33
    • 0029960028 scopus 로고    scopus 로고
    • Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
    • Kaptein A, Paillard V, Saunders M, (1996) Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J Biol Chem 271: 5961-5964.
    • (1996) J Biol Chem , vol.271 , pp. 5961-5964
    • Kaptein, A.1    Paillard, V.2    Saunders, M.3
  • 34
    • 0034163461 scopus 로고    scopus 로고
    • Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells
    • Ni Z, Lou W, Leman ES, Gao AC, (2000) Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells. Cancer Res 60: 1225-1228.
    • (2000) Cancer Res , vol.60 , pp. 1225-1228
    • Ni, Z.1    Lou, W.2    Leman, E.S.3    Gao, A.C.4
  • 36
    • 14444279192 scopus 로고    scopus 로고
    • Identification of a novel inhibitor of mitogen-activated protein kinase kinase
    • Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, et al. (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632.
    • (1998) J Biol Chem , vol.273 , pp. 18623-18632
    • Favata, M.F.1    Horiuchi, K.Y.2    Manos, E.J.3    Daulerio, A.J.4    Stradley, D.A.5
  • 37
    • 0028141496 scopus 로고
    • Transformation of mammalian cells by constitutively active MAP kinase kinase
    • Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, et al. (1994) Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265: 966-970.
    • (1994) Science , vol.265 , pp. 966-970
    • Mansour, S.J.1    Matten, W.T.2    Hermann, A.S.3    Candia, J.M.4    Rong, S.5
  • 38
    • 77955655466 scopus 로고    scopus 로고
    • Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation
    • Wei F, Xie Y, Tao L, Tang D, (2010) Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. Cell Signal 22: 1783-1789.
    • (2010) Cell Signal , vol.22 , pp. 1783-1789
    • Wei, F.1    Xie, Y.2    Tao, L.3    Tang, D.4
  • 39
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ, (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8: 755-768.
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 40
    • 0021254542 scopus 로고
    • Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
    • Gill GN, Kawamoto T, Cochet C, Le A, Sato JD, et al. (1984) Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity. J Biol Chem 259: 7755-7760.
    • (1984) J Biol Chem , vol.259 , pp. 7755-7760
    • Gill, G.N.1    Kawamoto, T.2    Cochet, C.3    Le, A.4    Sato, J.D.5
  • 41
    • 1842626080 scopus 로고    scopus 로고
    • Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer
    • Olapade-Olaopa EO, Moscatello DK, MacKay EH, Horsburgh T, Sandhu DP, et al. (2000) Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer. Br J Cancer 82: 186-194.
    • (2000) Br J Cancer , vol.82 , pp. 186-194
    • Olapade-Olaopa, E.O.1    Moscatello, D.K.2    MacKay, E.H.3    Horsburgh, T.4    Sandhu, D.P.5
  • 42
    • 43749096126 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation in prostate cancer by three novel missense mutations
    • Cai CQ, Peng Y, Buckley MT, Wei J, Chen F, et al. (2008) Epidermal growth factor receptor activation in prostate cancer by three novel missense mutations. Oncogene 27: 3201-3210.
    • (2008) Oncogene , vol.27 , pp. 3201-3210
    • Cai, C.Q.1    Peng, Y.2    Buckley, M.T.3    Wei, J.4    Chen, F.5
  • 43
    • 30944450821 scopus 로고    scopus 로고
    • Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
    • Livasy CA, Karaca G, Nanda R, Tretiakova MS, Olopade OI, et al. (2006) Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol 19: 264-271.
    • (2006) Mod Pathol , vol.19 , pp. 264-271
    • Livasy, C.A.1    Karaca, G.2    Nanda, R.3    Tretiakova, M.S.4    Olopade, O.I.5
  • 44
    • 10044232731 scopus 로고    scopus 로고
    • Prognostic significance of p53, Her-2, and EGFR overexpression in borderline and epithelial ovarian cancer
    • Nielsen JS, Jakobsen E, Holund B, Bertelsen K, Jakobsen A, (2004) Prognostic significance of p53, Her-2, and EGFR overexpression in borderline and epithelial ovarian cancer. Int J Gynecol Cancer 14: 1086-1096.
    • (2004) Int J Gynecol Cancer , vol.14 , pp. 1086-1096
    • Nielsen, J.S.1    Jakobsen, E.2    Holund, B.3    Bertelsen, K.4    Jakobsen, A.5
  • 45
    • 33748460152 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: correlation with androgen independence
    • Shah RB, Ghosh D, Elder JT, (2006) Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: correlation with androgen independence. Prostate 66: 1437-1444.
    • (2006) Prostate , vol.66 , pp. 1437-1444
    • Shah, R.B.1    Ghosh, D.2    Elder, J.T.3
  • 46
    • 36749067330 scopus 로고    scopus 로고
    • Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer
    • Schlomm T, Kirstein P, Iwers L, Daniel B, Steuber T, et al. (2007) Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer. Clin Cancer Res 13: 6579-6584.
    • (2007) Clin Cancer Res , vol.13 , pp. 6579-6584
    • Schlomm, T.1    Kirstein, P.2    Iwers, L.3    Daniel, B.4    Steuber, T.5
  • 47
    • 0027225697 scopus 로고
    • Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas
    • Garcia de Palazzo IE, Adams GP, Sundareshan P, Wong AJ, Testa JR, et al. (1993) Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas. Cancer Res 53: 3217-3220.
    • (1993) Cancer Res , vol.53 , pp. 3217-3220
    • Garcia de Palazzo, I.E.1    Adams, G.P.2    Sundareshan, P.3    Wong, A.J.4    Testa, J.R.5
  • 48
    • 84857601265 scopus 로고    scopus 로고
    • Pathobiological implications of the expression of EGFR, pAkt, NF-kappaB and MIC-1 in prostate cancer stem cells and their progenies
    • Mimeault M, Johansson SL, Batra SK, (2012) Pathobiological implications of the expression of EGFR, pAkt, NF-kappaB and MIC-1 in prostate cancer stem cells and their progenies. PLoS One 7: e31919.
    • (2012) PLoS One , vol.7
    • Mimeault, M.1    Johansson, S.L.2    Batra, S.K.3
  • 49
    • 44849106532 scopus 로고    scopus 로고
    • Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells
    • Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, et al. (2008) Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem 283: 10958-10966.
    • (2008) J Biol Chem , vol.283 , pp. 10958-10966
    • Soeda, A.1    Inagaki, A.2    Oka, N.3    Ikegame, Y.4    Aoki, H.5
  • 50
    • 77957351780 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis
    • Mazzoleni S, Politi LS, Pala M, Cominelli M, Franzin A, et al. (2010) Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. Cancer Res 70: 7500-7513.
    • (2010) Cancer Res , vol.70 , pp. 7500-7513
    • Mazzoleni, S.1    Politi, L.S.2    Pala, M.3    Cominelli, M.4    Franzin, A.5
  • 51
    • 78649831949 scopus 로고    scopus 로고
    • Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells
    • Sunayama J, Matsuda K, Sato A, Tachibana K, Suzuki K, et al. (2010) Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells. Stem Cells 28: 1930-1939.
    • (2010) Stem Cells , vol.28 , pp. 1930-1939
    • Sunayama, J.1    Matsuda, K.2    Sato, A.3    Tachibana, K.4    Suzuki, K.5
  • 52
    • 78651454089 scopus 로고    scopus 로고
    • EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling
    • Chang CJ, Yang JY, Xia W, Chen CT, Xie X, et al. (2011) EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling. Cancer Cell 19: 86-100.
    • (2011) Cancer Cell , vol.19 , pp. 86-100
    • Chang, C.J.1    Yang, J.Y.2    Xia, W.3    Chen, C.T.4    Xie, X.5
  • 53
    • 80053574588 scopus 로고    scopus 로고
    • The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells
    • Hong SK, Kim JH, Lin MF, Park JI, (2011) The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells. Exp Cell Res 317: 2671-2682.
    • (2011) Exp Cell Res , vol.317 , pp. 2671-2682
    • Hong, S.K.1    Kim, J.H.2    Lin, M.F.3    Park, J.I.4
  • 54
    • 0033555967 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase associated with prostate cancer progression
    • Gioeli D, Mandell JW, Petroni GR, Frierson HF Jr, Weber MJ, (1999) Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 59: 279-284.
    • (1999) Cancer Res , vol.59 , pp. 279-284
    • Gioeli, D.1    Mandell, J.W.2    Petroni, G.R.3    Frierson Jr., H.F.4    Weber, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.