Stem cells: The root of prostate cancer?

Journal of Cellular Physiology

Volumn 216, Issue 2, 2008, Pages 332-336

  Kasper, Susan ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD24 ANTIGEN; HERMES ANTIGEN; PROTEIN P63; STEM CELL FACTOR; TELOMERASE REVERSE TRANSCRIPTASE;

CANCER GROWTH; CANCER STEM CELL; CARCINOGENESIS; CELL FUNCTION; CELL ISOLATION; CELL RENEWAL; CELL SURVIVAL; CELLULAR DISTRIBUTION; HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CANCER; SHORT SURVEY;

ANIMALS; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; PROSTATE; PROSTATIC NEOPLASMS; STEM CELLS; TUMOR MARKERS, BIOLOGICAL;

EID: 46049102201     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21489     Document Type: Short Survey

References (48)

1. Al Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. 2003. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 100:3983-3988.
2. Balk SP, Knudsen KE. 2008. AR, the cell cycle, and prostate cancer. Nucl Recept Signal 6:e001-.
3. Bell DR, Van Zant G. 2004. Stem cells, aging, and cancer: Inevitabilities and outcomes. Oncogene 23:7290-7296.
4. Bonkhoff H, Remberger K. 1996. Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: A stem cell model. Prostate 28:98-106.
5. Bonkhoff H, Stein U, Remberger K. 1994. The proliferative function of basal cells in the normal and hyperplastic human prostate. Prostate 24:114-118.
6. Burger PE, Xiong X, Coetzee S, Salm SN, Moscatelli D, Goto K, Wilson EL. 2005. Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue. Proc Natl Acad Sci U S A 102:7180-7185.
7. Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, Visvader J, Weissman IL, Wahl GM. 2006. Cancer stem cells - perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 66:9339-9344.
8. Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. 2005. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65:10946-10951.
9. Craft N, Chhor C, Tran C, Belldegrun A, DeKernion J, Witte ON, Said J, Reiter RE, Sawyers CL. 1999. Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process. Cancer Res 59:5030-5036.
10. Cunha GR, Fujii H, Neubauer BL, Shannon JM, Sawyer L, Reese BA. 1983. Epithelial-mesenchymal interactions in prostatic development. I. Morphological observations of prostatic induction by urogenital sinus mesenchyme in epithelium of the adult rodent urinary bladder. J Cell Biol 96:1662-1670.
11. De Marzo AM, Meeker AK, Epstein JI, Coffey DS. 1998a. Prostate stem cell compartments: Expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. Am J Pathol 153:911-919.
12. De Marzo AM, Nelson WG, Meeker AK, Coffey DS. 1998b. Stem cell features of benign and malignant prostate epithelial cells. J Urol 160:2381-2392.
13. Demichelis F, Rubin MA. 2007. TMPRSS2-ETS fusion prostate cancer: Biological and clinical implications. J Clin Pathol 60:1185-1186.
14. Denmeade SR, Lin XS, Isaacs JT. 1996. Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer. Prostate 28:251-265.
15. Fargeas CA, Joester A, Missol-Kolka E, Hellwig A, Huttner WB, Corbeil D. 2004. Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis. J Cell Sci 117:4301-4311.
16. Feinberg AP. 2007. Phenotypic plasticity and the epigenetics of human disease. Nature 447:433-440.
17. Feinberg AP, Ohlsson R, Henikoff S. 2006. The epigenetic progenitor origin of human cancer. Nat Rev Genet 7:21-33.
18. Feldman BJ, Feldman D. 2001. The development of androgen-independent prostate cancer. Nat Rev Cancer 1:34-45.
19. Gu G, Yuan J, Wills ML, Kasper S. 2007. Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer Res 67:4807-4815.
20. Huntly BJ, Gilliland DG. 2005. Cancer biology: Summing up cancer stem cells. Nature 435:1169-1170.
21. Hurt EM, Kawasaki BT, Klarmann GJ, Thomas SB, Farrar WL. 2008. CD44(+)CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. Br J Cancer 98:756-765.
22. Huss WJ, Gray DR, Greenberg NM, Mohler JL, Smith GJ. 2005. Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Cancer Res 65:6640-6650.
23. Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. 2006. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 12:1167-1174.
24. Kinbara H, Cunha GR, Boutin E, Hayashi N, Kawamura J. 1996. Evidence of stem cells in the adult prostatic epithelium based upon responsiveness to mesenchymal inductors. Prostate 29:107-116.
25. Krivtsov AV, Armstrong SA. 2007. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 7:823-833.
26. Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA. 2006. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF 442:818-822.
27. Kurita T, Medina RT, Mills AA, Cunha GR. 2004. Role of p63 and basal cells in the prostate. Development 131:4955-4964.
28. Lawson DA, Witte ON. 2007. Stem cells in prostate cancer initiation and progression. J Clin Invest 117:2044-2050.
29. Lawson DA, Xin L, Lukacs RU, Cheng D, Witte ON. 2007. Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci U S A 104:181-186.
30. Li Y, Rosen JM. 2005. Stem/progenitor cells in mouse mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 10:17-24.
31. Liu AY, Peehl DM. 2001. Characterization of cultured human prostatic epithelial cells by cluster designation antigen expression. Cell Tissue Res 305:389-397.
32. McCarthy N. 2007. Cancer stem cells: Underground movement. Nat Rev Cancer 7:812-813.
33. Mundy GR. 2002. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer 2:584-593.
34. Patrawala L, Calhoun T, Schneider-Broussard R, Li H, Bhatia B, Tang S, Reilly JG, Chandra D, Zhou J, Claypool K, Coghlan L, Tang DG. 2006. Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 25:1696-1708.
35. Polyak K, Hahn WC. 2006. Roots and stems: Stem cells in cancer. Nat Med 12:296-300.
36. Richardson GD, Robson CN, Lang SH, Neal DE, Maitland NJ, Collins AT. 2004. CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 117:3539-3545.
37. Sell S. 2004. Stem cell origin of cancer and differentiation therapy. Crit Rev Oncol Hematol 51:1-28.
38. Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J, Nikolskaya T, Serebryiskaya T, Beroukhim R, Hu M, Halushka MK, Sukumar S, Parker LM, Anderson KS, Harris LN, Garber JE, Richardson AL, Schnitt SJ, Nikolsky Y, Gelman RS, Polyak K. 2007. Molecular definition of breast tumor heterogeneity. Cancer Cell 11:259-273.
39. Signoretti S, Pires MM, Lindauer M, Horner JW, Grisanzio C, Dhar S, Majumder P, McKeon F, Kantoff PW, Sellers WR, Loda M. 2005. p63 regulates commitment to the prostate cell lineage. Proc Natl Acad Sci U S A 102:11355-11360.
40. Signoretti S, Waltregny D, Dilks J, Isaac B, Lin D, Garraway L, Yang A, Montironi R, McKeon F, Loda M. 2000. p63 is a prostate basal cell marker and is required for prostate development. Am J Pathol 157:1769-1775.
41. Tang DG, Patrawala L, Calhoun T, Bhatia B, Choy G, Schneider-Broussard R, Jeter C. 2007. Prostate cancer stem/progenitor cells: Identification, characterization, and implications. Mol Carcinog 46:1-14.
42. Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE, Cao Q, Prensner JR, Rubin MA, Shah RB, Mehra R, Chinnaiyan AM. 2008. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 10:177-188.
43. Tsujimura A, Koikawa Y, Salm S, Takao T, Coetzee S, Moscatelli D, Shapiro E, Lepor H, Sun TT, Wilson EL. 2002. Proximal location of mouse prostate epithelial stem cells: A model of prostatic homeostasis. J Cell Biol 157:1257-1265.
44. Uzgare AR, Xu Y, Isaacs JT. 2004. In vitro culturing and characteristics of transit amplifying epithelial cells from human prostate tissue. J Cell Biochem 91:196-205.
45. Verhagen AP, Ramaekers FC, Aalders TW, Schaafsma HE, Debruyne FM, Schalken JA. 1992. Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer. Cancer Res 52:6182-6187.
46. Wang S, Garcia AJ, Wu M, Lawson DA, Witte ON, Wu H. 2006. Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation. Proc Natl Acad Sci U S A 103:1480-1485.
47. Xin L, Lawson DA, Witte ON. 2005. The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis. Proc Natl Acad Sci U S A 102:6942-6947.
48. Yoshimoto M, Joshua AM, Chilton-Macneill S, Bayani J, Selvarajah S, Evans AJ, Zielenska M, Squire JA. 2006. Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement. Neoplasia 8:465-469.