Inhibition of delta-like ligand 4 decreases Th1/Th17 response in a mouse model of multiple sclerosis

Neuroscience Letters

Volumn 541, Issue , 2013, Pages 161-166

  Eixarch, Herena ^a   Mansilla, M José ^a   Costa, Carme ^a   Kunkel, Steve L ^b   Montalban, Xavier ^a   Godessart, Núria ^c   Espejo, Carmen ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c R and D Center Almirall SA ^*  (Spain)

Author keywords

Dll4; EAE; Multiple sclerosis; Notch; Th17

Indexed keywords

DELTA LIKE LIGAND 4 ANTIBODY; IMMUNOMODULATING AGENT; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MODEL; DRUG EFFICACY; DRUG RESPONSE; FEMALE; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH17 CELL;

ANIMALS; ANTIBODIES, NEUTRALIZING; CELL PROLIFERATION; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MULTIPLE SCLEROSIS; SPLEEN; TH1-TH2 BALANCE;

EID: 84876420699     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.02.038     Document Type: Article

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