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Volumn 2 JUL, Issue , 2012, Pages

How does ionizing irradiation contribute to the induction of anti-tumor immunity?

Author keywords

Abscopal effects; AnnexinA5; Dendritic cells; Hyperthermia; Immune modulation; Immune therapy; Immunogenic cancer cell death; Low and high dose ionizing irradiation

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; LIPOCORTIN 5; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84876416160     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2012.00075     Document Type: Review
Times cited : (69)

References (112)
  • 2
    • 38449092036 scopus 로고    scopus 로고
    • Combination of direct intratumoral administration of dendritic cells and irradiation induces strong systemic antitumor effect mediated by GRP94/gp96 against squamous cell carcinoma in mice
    • Akutsu, Y., Matsubara, H., Urashima, T., Komatsu, A., Sakata, H., Nishimori, T., Yoneyama, Y., Hoshino, I., Murakami, K., Usui, A., Kano, M., and Ochiai, T. (2007). Combination of direct intratumoral administration of dendritic cells and irradiation induces strong systemic antitumor effect mediated by GRP94/gp96 against squamous cell carcinoma in mice. Int. J. Oncol. 31, 509-515.
    • (2007) Int. J. Oncol. , vol.31 , pp. 509-515
    • Akutsu, Y.1    Matsubara, H.2    Urashima, T.3    Komatsu, A.4    Sakata, H.5    Nishimori, T.6    Yoneyama, Y.7    Hoshino, I.8    Murakami, K.9    Usui, A.10    Kano, M.11    Ochiai, T.12
  • 3
    • 80054728443 scopus 로고    scopus 로고
    • Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis
    • Anders, H. J., and Ryu, M. (2011). Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis. Kidney Int. 80, 915-925.
    • (2011) Kidney Int. , vol.80 , pp. 915-925
    • Anders, H.J.1    Ryu, M.2
  • 4
    • 0017257355 scopus 로고
    • Ionizing radiation and the immune response
    • Anderson, R. E., and Warner, N. L. (1976). Ionizing radiation and the immune response. Adv. Immunol. 24, 215-335.
    • (1976) Adv. Immunol. , vol.24 , pp. 215-335
    • Anderson, R.E.1    Warner, N.L.2
  • 5
    • 0017365178 scopus 로고
    • Lymphangiographic demonstration of the abscopal effect in patients with malignant lymphomas
    • Antoniades, J., Brady, L. W., and Lightfoot, D. A. (1977). Lymphangiographic demonstration of the abscopal effect in patients with malignant lymphomas. Int. J. Radiat. Oncol. Biol. Phys. 2, 141-147.
    • (1977) Int. J. Radiat. Oncol. Biol. Phys. , vol.2 , pp. 141-147
    • Antoniades, J.1    Brady, L.W.2    Lightfoot, D.A.3
  • 7
    • 3042747506 scopus 로고    scopus 로고
    • Mortality of employees of the United Kingdom Atomic Energy Authority, 1946-97
    • Atkinson, W. D., Law, D. V., Bromley, K. J., and Inskip, H. M. (2004). Mortality of employees of the United Kingdom Atomic Energy Authority, 1946-97. Occup. Environ. Med. 61, 577-585.
    • (2004) Occup. Environ. Med. , vol.61 , pp. 577-585
    • Atkinson, W.D.1    Law, D.V.2    Bromley, K.J.3    Inskip, H.M.4
  • 8
    • 0035895240 scopus 로고    scopus 로고
    • Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells
    • Azzam, E. I., De Toledo, S. M., and Little, J. B. (2001). Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells. Proc. Natl. Acad. Sci. U.S.A. 98, 473-478.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 473-478
    • Azzam, E.I.1    De Toledo, S.M.2    Little, J.B.3
  • 9
    • 0033747044 scopus 로고    scopus 로고
    • Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway
    • Basu, S., Binder, R. J., Suto, R., Anderson, K. M., and Srivastava, P. K. (2000). Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int. Immunol. 12, 1539-1546.
    • (2000) Int. Immunol. , vol.12 , pp. 1539-1546
    • Basu, S.1    Binder, R.J.2    Suto, R.3    Anderson, K.M.4    Srivastava, P.K.5
  • 10
    • 84855490596 scopus 로고    scopus 로고
    • Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress
    • Bauer, M., Goldstein, M., Christmann, M., Becker, H., Heylmann, D., and Kaina, B. (2011). Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 108, 21105-21110.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 21105-21110
    • Bauer, M.1    Goldstein, M.2    Christmann, M.3    Becker, H.4    Heylmann, D.5    Kaina, B.6
  • 11
    • 84891648735 scopus 로고    scopus 로고
    • The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death
    • Beyer, C., Stearns, N. A., Giessl, A., Distler, J. H., Schett, G., and Pisetsky, D. (2012). The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death. Innate Immun. 16, 16.
    • (2012) Innate Immun. , vol.16 , pp. 16
    • Beyer, C.1    Stearns, N.A.2    Giessl, A.3    Distler, J.H.4    Schett, G.5    Pisetsky, D.6
  • 12
    • 33646372972 scopus 로고    scopus 로고
    • Cancer mortality among populations residing in counties near the Hanford site, 1950-2000
    • Boice, J. D. Jr., Mumma, M. T., and Blot, W. J. (2006). Cancer mortality among populations residing in counties near the Hanford site, 1950-2000. Health Phys. 90, 431-445.
    • (2006) Health Phys. , vol.90 , pp. 431-445
    • Boice Jr., J.D.1    Mumma, M.T.2    Blot, W.J.3
  • 14
    • 0031684172 scopus 로고    scopus 로고
    • Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia
    • Burd, R., Dziedzic, T. S., Xu, Y., Caligiuri, M. A., Subjeck, J. R., and Repasky, E. A. (1998). Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia. J. Cell. Physiol. 177, 137-147.
    • (1998) J. Cell. Physiol. , vol.177 , pp. 137-147
    • Burd, R.1    Dziedzic, T.S.2    Xu, Y.3    Caligiuri, M.A.4    Subjeck, J.R.5    Repasky, E.A.6
  • 16
    • 63149158731 scopus 로고    scopus 로고
    • Heat shock protein 70, released from heat-stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway
    • Chen, T., Guo, J., Han, C., Yang, M., and Cao, X. (2009). Heat shock protein 70, released from heat-stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway. J. Immunol. 182, 1449-1459.
    • (2009) J. Immunol. , vol.182 , pp. 1449-1459
    • Chen, T.1    Guo, J.2    Han, C.3    Yang, M.4    Cao, X.5
  • 17
    • 70349232480 scopus 로고    scopus 로고
    • Differential effects of irradiation with carbon ions and x-rays on macrophage function
    • Conrad, S., Ritter, S., Fournier, C., and Nixdorff, K. (2009). Differential effects of irradiation with carbon ions and x-rays on macrophage function. J. Radiat. Res. 50, 223-231.
    • (2009) J. Radiat. Res. , vol.50 , pp. 223-231
    • Conrad, S.1    Ritter, S.2    Fournier, C.3    Nixdorff, K.4
  • 19
    • 80051890661 scopus 로고    scopus 로고
    • Development of bavituximab, a vascular targeting agent with immune-modulating properties, for lung cancer treatment
    • Derose, P., Thorpe, P. E., and Gerber, D. E. (2011). Development of bavituximab, a vascular targeting agent with immune-modulating properties, for lung cancer treatment. Immunotherapy 3, 933-944.
    • (2011) Immunotherapy , vol.3 , pp. 933-944
    • Derose, P.1    Thorpe, P.E.2    Gerber, D.E.3
  • 20
    • 69949085196 scopus 로고    scopus 로고
    • Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody
    • Dewan, M. Z., Galloway, A. E., Kawashima, N., Dewyngaert, J. K., Babb, J. S., Formenti, S. C., and Demaria, S. (2009). Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. Clin. Cancer Res. 15, 5379-5388.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5379-5388
    • Dewan, M.Z.1    Galloway, A.E.2    Kawashima, N.3    Dewyngaert, J.K.4    Babb, J.S.5    Formenti, S.C.6    Demaria, S.7
  • 21
    • 0037326299 scopus 로고    scopus 로고
    • Antitumor effect of secreted Flt3-ligand can act at distant tumor sites in a murine model of head and neck cancer
    • Dong, J., Bohinski, R. J., Li, Y. Q., Van Waes, C., Hendler, F., Gleich, L., and Stambrook, P. J. (2003). Antitumor effect of secreted Flt3-ligand can act at distant tumor sites in a murine model of head and neck cancer. Cancer Gene Ther. 10, 96-104.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 96-104
    • Dong, J.1    Bohinski, R.J.2    Li, Y.Q.3    Van Waes, C.4    Hendler, F.5    Gleich, L.6    Stambrook, P.J.7
  • 23
    • 85027933609 scopus 로고    scopus 로고
    • The immune functions of phosphatidylserine in membranes of dying cells and microvesicles
    • Frey, B., and Gaipl, U. S. (2011). The immune functions of phosphatidylserine in membranes of dying cells and microvesicles. Semin. Immunopathol. 33, 497-516.
    • (2011) Semin. Immunopathol. , vol.33 , pp. 497-516
    • Frey, B.1    Gaipl, U.S.2
  • 24
    • 84860503128 scopus 로고    scopus 로고
    • Induction of abscopal anti-tumor immunity and immunogenic tumor cell death by ionizing irradiation-implications for cancer therapies
    • Frey, B., Rubner, Y., Wunderlich, R., Weiss, E. M., Pockley, A. G., Fietkau, R., and Gaipl, U. S. (2012). Induction of abscopal anti-tumor immunity and immunogenic tumor cell death by ionizing irradiation-implications for cancer therapies. Curr. Med. Chem. 12, 1751-1764.
    • (2012) Curr. Med. Chem. , vol.12 , pp. 1751-1764
    • Frey, B.1    Rubner, Y.2    Wunderlich, R.3    Weiss, E.M.4    Pockley, A.G.5    Fietkau, R.6    Gaipl, U.S.7
  • 26
    • 0242552753 scopus 로고    scopus 로고
    • Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex
    • Fujihara, M., Muroi, M., Tanamoto, K., Suzuki, T., Azuma, H., and Ikeda, H. (2003). Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex. Pharmacol. Ther. 100, 171-194.
    • (2003) Pharmacol. Ther. , vol.100 , pp. 171-194
    • Fujihara, M.1    Muroi, M.2    Tanamoto, K.3    Suzuki, T.4    Azuma, H.5    Ikeda, H.6
  • 27
    • 70749109084 scopus 로고    scopus 로고
    • Activation-induced cell death and total Akt content of granulocytes show a biphasic course after low-dose radiation
    • Gaipl, U. S., Meister, S., Lodermann, B., Rodel, F., Fietkau, R., Herrmann, M., Kern, P. M., and Frey, B. (2009). Activation-induced cell death and total Akt content of granulocytes show a biphasic course after low-dose radiation. Autoimmunity 42, 340-342.
    • (2009) Autoimmunity , vol.42 , pp. 340-342
    • Gaipl, U.S.1    Meister, S.2    Lodermann, B.3    Rodel, F.4    Fietkau, R.5    Herrmann, M.6    Kern, P.M.7    Frey, B.8
  • 29
    • 34548862588 scopus 로고    scopus 로고
    • Radiation-enhanced vascular targeting of human lung cancers in mice with a monoclonal antibody that binds anionic phospholipids
    • He, J., Luster, T. A., and Thorpe, P. E. (2007). Radiation-enhanced vascular targeting of human lung cancers in mice with a monoclonal antibody that binds anionic phospholipids. Clin. Cancer Res. 13, 5211-5218.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5211-5218
    • He, J.1    Luster, T.A.2    Thorpe, P.E.3
  • 30
    • 72549108621 scopus 로고    scopus 로고
    • Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of glioblastoma
    • He, J., Yin, Y., Luster, T. A., Watkins, L., and Thorpe, P. E. (2009). Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of glioblastoma. Clin. Cancer Res. 15, 6871-6880.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 6871-6880
    • He, J.1    Yin, Y.2    Luster, T.A.3    Watkins, L.4    Thorpe, P.E.5
  • 31
    • 0037336996 scopus 로고    scopus 로고
    • Inhibition of the iNOS pathway in inflammatory macrophages by low-dose X-irradiation in vitro. Is there a time dependence?
    • Hildebrandt, G., Loppnow, G., Jahns, J., Hindemith, M., Anderegg, U., Saalbach, A., and Kamprad, F. (2003). Inhibition of the iNOS pathway in inflammatory macrophages by low-dose X-irradiation in vitro. Is there a time dependence? Strahlenther. Onkol. 179, 158-166.
    • (2003) Strahlenther. Onkol. , vol.179 , pp. 158-166
    • Hildebrandt, G.1    Loppnow, G.2    Jahns, J.3    Hindemith, M.4    Anderegg, U.5    Saalbach, A.6    Kamprad, F.7
  • 33
    • 52649153457 scopus 로고    scopus 로고
    • Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges
    • discussion 1075, 1080-1081, 1084
    • Hodge, J. W., Guha, C., Neefjes, J., and Gulley, J. L. (2008). Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges. Oncology (Williston Park, N.Y.) 22, 1064-1070; discussion 1075, 1080-1081, 1084.
    • (2008) Oncology (Williston Park, N.Y.) , vol.22 , pp. 1064-1070
    • Hodge, J.W.1    Guha, C.2    Neefjes, J.3    Gulley, J.L.4
  • 35
    • 0027409235 scopus 로고
    • Suppressive effect of low dose total body irradiation on lung metastasis: dose dependency and effective period
    • Hosoi, Y., and Sakamoto, K. (1993). Suppressive effect of low dose total body irradiation on lung metastasis: dose dependency and effective period. Radiother. Oncol. 26, 177-179.
    • (1993) Radiother. Oncol. , vol.26 , pp. 177-179
    • Hosoi, Y.1    Sakamoto, K.2
  • 38
    • 30044434256 scopus 로고    scopus 로고
    • The mononuclear phagocyte system
    • Hume, D. A. (2006). The mononuclear phagocyte system. Curr. Opin. Immunol. 18, 49-53.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 49-53
    • Hume, D.A.1
  • 39
    • 12844265986 scopus 로고    scopus 로고
    • Suppression of thymic lymphoma induction by life-long low-dose-rate irradiation accompanied by immune activation in C57BU6 mice
    • Ina, Y., Tanooka, H., Yamada, T., and Sakai, K. (2005). Suppression of thymic lymphoma induction by life-long low-dose-rate irradiation accompanied by immune activation in C57BU6 mice. Radiat. Res. 163, 153-158.
    • (2005) Radiat. Res. , vol.163 , pp. 153-158
    • Ina, Y.1    Tanooka, H.2    Yamada, T.3    Sakai, K.4
  • 41
    • 0034161938 scopus 로고    scopus 로고
    • Factors underlying the cell growth-related bystander responses to alpha particles
    • Iyer, R., Lehnert, B. E., and Svensson, R. (2000). Factors underlying the cell growth-related bystander responses to alpha particles. Cancer Res. 60, 1290-1298.
    • (2000) Cancer Res. , vol.60 , pp. 1290-1298
    • Iyer, R.1    Lehnert, B.E.2    Svensson, R.3
  • 42
    • 0023841388 scopus 로고
    • T cell potentiation in normal and autoimmune-prone mice after extended exposure to low doses of ionizing radiation and/or caloric restriction
    • James, S. J., and Makinodan, T. (1988). T cell potentiation in normal and autoimmune-prone mice after extended exposure to low doses of ionizing radiation and/or caloric restriction. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 53, 137-152.
    • (1988) Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. , vol.53 , pp. 137-152
    • James, S.J.1    Makinodan, T.2
  • 43
    • 75649114088 scopus 로고    scopus 로고
    • Whole-body low dose irradiation promotes the efficacy of conventional radiotherapy for cancer and possible mechanisms
    • Jin, S. Z., Pan, X. N., Wu, N., Jin, G. H., and Liu, S. Z. (2007). Whole-body low dose irradiation promotes the efficacy of conventional radiotherapy for cancer and possible mechanisms. Dose Response 5, 349-358.
    • (2007) Dose Response , vol.5 , pp. 349-358
    • Jin, S.Z.1    Pan, X.N.2    Wu, N.3    Jin, G.H.4    Liu, S.Z.5
  • 46
    • 0032773089 scopus 로고    scopus 로고
    • In vitro apoptosis in peripheral blood mononuclear cells induced by low-dose radiotherapy displays a discontinuous dose-dependence
    • Kern, P., Keilholz, L., Forster, C., Seegenschmiedt, M. H., Sauer, R., and Herrmann, M. (1999). In vitro apoptosis in peripheral blood mononuclear cells induced by low-dose radiotherapy displays a discontinuous dose-dependence. Int. J. Radiat. Biol. 75, 995-1003.
    • (1999) Int. J. Radiat. Biol. , vol.75 , pp. 995-1003
    • Kern, P.1    Keilholz, L.2    Forster, C.3    Seegenschmiedt, M.H.4    Sauer, R.5    Herrmann, M.6
  • 48
    • 0016816906 scopus 로고
    • An interesting case of possible abscopal effect in malignant melanoma
    • Kingsley, D. P. (1975). An interesting case of possible abscopal effect in malignant melanoma. Br. J. Radiol. 48, 863-866.
    • (1975) Br. J. Radiol. , vol.48 , pp. 863-866
    • Kingsley, D.P.1
  • 49
    • 0025711246 scopus 로고
    • Therapeutic efficacy of pre-operative radiotherapy on breast carcinoma: in special reference to its abscopal effect on metastatic lymph-nodes
    • Konoeda, K. (1990). Therapeutic efficacy of pre-operative radiotherapy on breast carcinoma: in special reference to its abscopal effect on metastatic lymph-nodes. Nihon Gan Chiryo Gakkai Shi 25, 1204-1214.
    • (1990) Nihon Gan Chiryo Gakkai Shi , vol.25 , pp. 1204-1214
    • Konoeda, K.1
  • 50
    • 0030701975 scopus 로고    scopus 로고
    • Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer
    • Kwong, Y. L., Chen, S. H., Kosai, K., Finegold, M., and Woo, S. L. (1997). Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer. Chest 112, 1332-1337.
    • (1997) Chest , vol.112 , pp. 1332-1337
    • Kwong, Y.L.1    Chen, S.H.2    Kosai, K.3    Finegold, M.4    Woo, S.L.5
  • 52
    • 83655203205 scopus 로고    scopus 로고
    • Apoptosis induction and tumor cell repopulation: the yin and yang of radiotherapy
    • Lauber, K., Munoz, L. E., Berens, C., Jendrossek, V., Belka, C., and Herrmann, M. (2011). Apoptosis induction and tumor cell repopulation: the yin and yang of radiotherapy. Radiat. Oncol. 6, 176.
    • (2011) Radiat. Oncol. , vol.6 , pp. 176
    • Lauber, K.1    Munoz, L.E.2    Berens, C.3    Jendrossek, V.4    Belka, C.5    Herrmann, M.6
  • 53
    • 70149113060 scopus 로고    scopus 로고
    • Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment
    • Lee, Y., Auh, S. L., Wang, Y., Burnette, B., Meng, Y., Beckett, M., Sharma, R., Chin, R., Tu, T., Weichselbaum, R. R., and Fu, Y. X. (2009). Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood 114, 589-595.
    • (2009) Blood , vol.114 , pp. 589-595
    • Lee, Y.1    Auh, S.L.2    Wang, Y.3    Burnette, B.4    Meng, Y.5    Beckett, M.6    Sharma, R.7    Chin, R.8    Tu, T.9    Weichselbaum, R.R.10    Fu, Y.X.11
  • 54
    • 0038353620 scopus 로고    scopus 로고
    • On radiation hormesis expressed in the immune system
    • Liu, S. Z. (2003). On radiation hormesis expressed in the immune system. Crit. Rev. Toxicol. 33, 431-441.
    • (2003) Crit. Rev. Toxicol. , vol.33 , pp. 431-441
    • Liu, S.Z.1
  • 55
    • 40049106452 scopus 로고    scopus 로고
    • Cancer control related to stimulation of immunity by low-dose radiation
    • Liu, S. Z. (2007). Cancer control related to stimulation of immunity by low-dose radiation. Dose Response 5, 39-47.
    • (2007) Dose Response , vol.5 , pp. 39-47
    • Liu, S.Z.1
  • 56
    • 0023278839 scopus 로고
    • Radiation hormesis: its expression in the immune system
    • Liu, S. Z., Liu, W. H., and Sun, J. B. (1987). Radiation hormesis: its expression in the immune system. Health Phys. 52, 579-583.
    • (1987) Health Phys. , vol.52 , pp. 579-583
    • Liu, S.Z.1    Liu, W.H.2    Sun, J.B.3
  • 57
    • 84867017339 scopus 로고    scopus 로고
    • Low dose ionising radiation leads to a NF-kappaB dependent decreased secretion of active IL-1beta by activated macrophages with a discontinuous dose-dependency
    • PMID:22545750. [Epub ahead of print].
    • Lodermann, B., Wunderlich, R., Frey, S., Schorn, C., Stangl, S., Rodel, F., Keilholz, L., Fietkau, R., Gaipl, U. S., and Frey, B. (2012). Low dose ionising radiation leads to a NF-kappaB dependent decreased secretion of active IL-1beta by activated macrophages with a discontinuous dose-dependency. Int. J. Radiat. Biol. PMID:22545750. [Epub ahead of print].
    • (2012) Int. J. Radiat. Biol.
    • Lodermann, B.1    Wunderlich, R.2    Frey, S.3    Schorn, C.4    Stangl, S.5    Rodel, F.6    Keilholz, L.7    Fietkau, R.8    Gaipl, U.S.9    Frey, B.10
  • 58
    • 20444406500 scopus 로고    scopus 로고
    • Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
    • Lugade, A. A., Moran, J. P., Gerber, S. A., Rose, R. C., Frelinger, J. G., and Lord, E. M. (2005). Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J. Immunol. 174, 7516-7523.
    • (2005) J. Immunol. , vol.174 , pp. 7516-7523
    • Lugade, A.A.1    Moran, J.P.2    Gerber, S.A.3    Rose, R.C.4    Frelinger, J.G.5    Lord, E.M.6
  • 61
    • 27744543102 scopus 로고    scopus 로고
    • Inflammatory cells during wound repair: the good, the bad and the ugly
    • Martin, P., and Leibovich, S. J. (2005). Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol. 15, 599-607.
    • (2005) Trends Cell Biol. , vol.15 , pp. 599-607
    • Martin, P.1    Leibovich, S.J.2
  • 62
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger, P. (1994). Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12, 991-1045.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 63
    • 0034784261 scopus 로고    scopus 로고
    • The mortality and cancer morbidity experience of employees at the Chapelcross plant of British Nuclear Fuels plc, 1955-95
    • McGeoghegan, D., and Binks, K. (2001). The mortality and cancer morbidity experience of employees at the Chapelcross plant of British Nuclear Fuels plc, 1955-95. J. Radiol. Prot. 21, 221-250.
    • (2001) J. Radiol. Prot. , vol.21 , pp. 221-250
    • McGeoghegan, D.1    Binks, K.2
  • 64
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • Mellman, I., Coukos, G., and Dranoff, G. (2011). Cancer immunotherapy comes of age. Nature 480, 480-489.
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1    Coukos, G.2    Dranoff, G.3
  • 65
    • 0013071190 scopus 로고
    • Whole body irradiation; radiobiology or medicine?
    • Mole, R. H. (1953). Whole body irradiation; radiobiology or medicine? Br. J. Radiol. 26, 234-241.
    • (1953) Br. J. Radiol. , vol.26 , pp. 234-241
    • Mole, R.H.1
  • 66
    • 0033178409 scopus 로고    scopus 로고
    • Overview of the epidemiology of malignancy in immune deficiency
    • Mueller, N. (1999). Overview of the epidemiology of malignancy in immune deficiency. J. Acquir. Immune Defic. Syndr. 21, S5-S10.
    • (1999) J. Acquir. Immune Defic. Syndr. , vol.21
    • Mueller, N.1
  • 67
    • 0014558950 scopus 로고
    • The abscopal effect in malignant lymphoma and its relationship to lymphocyte circulation
    • Nobler, M. P. (1969). The abscopal effect in malignant lymphoma and its relationship to lymphocyte circulation. Radiology 93, 410-412.
    • (1969) Radiology , vol.93 , pp. 410-412
    • Nobler, M.P.1
  • 70
    • 79952704114 scopus 로고    scopus 로고
    • Abscopal effect of radiation on lung metastases of hepatocellular carcinoma: a case report
    • Okuma, K., Yamashita, H., Niibe, Y., Hayakawa, K., and Nakagawa, K. (2011). Abscopal effect of radiation on lung metastases of hepatocellular carcinoma: a case report. J. Med. Case Reports 5, 111.
    • (2011) J. Med. Case Reports , vol.5 , pp. 111
    • Okuma, K.1    Yamashita, H.2    Niibe, Y.3    Hayakawa, K.4    Nakagawa, K.5
  • 71
    • 85027949846 scopus 로고    scopus 로고
    • Prognostic impact of anticancer immune responses: an introduction
    • Pages, F., and Kroemer, G. (2011). Prognostic impact of anticancer immune responses: an introduction. Semin. Immunopathol. 33, 317-319.
    • (2011) Semin. Immunopathol. , vol.33 , pp. 317-319
    • Pages, F.1    Kroemer, G.2
  • 72
    • 80052556774 scopus 로고    scopus 로고
    • HMGB1 and microparticles as mediators of the immune response to cell death
    • Pisetsky, D. S., Gauley, J., and Ullal, A. J. (2011). HMGB1 and microparticles as mediators of the immune response to cell death. Antioxid. Redox Signal. 15, 2209-2219.
    • (2011) Antioxid. Redox Signal. , vol.15 , pp. 2209-2219
    • Pisetsky, D.S.1    Gauley, J.2    Ullal, A.J.3
  • 74
    • 0028271882 scopus 로고
    • Activation of nuclear factor kappa B in human lymphoblastoid cells by low-dose ionizing radiation
    • Prasad, A. V., Mohan, N., Chandrasekar, B., and Meltz, M. L. (1994). Activation of nuclear factor kappa B in human lymphoblastoid cells by low-dose ionizing radiation. Radiat. Res. 138, 367-372.
    • (1994) Radiat. Res. , vol.138 , pp. 367-372
    • Prasad, A.V.1    Mohan, N.2    Chandrasekar, B.3    Meltz, M.L.4
  • 75
    • 0029129311 scopus 로고
    • Induction of transcription of "immediate early genes" by low-dose ionizing radiation
    • Prasad, A. V., Mohan, N., Chandrasekar, B., and Meltz, M. L. (1995). Induction of transcription of "immediate early genes" by low-dose ionizing radiation. Radiat. Res. 143, 263-272.
    • (1995) Radiat. Res. , vol.143 , pp. 263-272
    • Prasad, A.V.1    Mohan, N.2    Chandrasekar, B.3    Meltz, M.L.4
  • 77
    • 80255124055 scopus 로고    scopus 로고
    • In search of a novel target-phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy
    • Riedl, S., Rinner, B., Asslaber, M., Schaider, H., Walzer, S., Novak, A., Lohner, K., and Zweytick, D. (2011). In search of a novel target-phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy. Biochim. Biophys. Acta 1808, 2638-2645.
    • (2011) Biochim. Biophys. Acta , vol.1808 , pp. 2638-2645
    • Riedl, S.1    Rinner, B.2    Asslaber, M.3    Schaider, H.4    Walzer, S.5    Novak, A.6    Lohner, K.7    Zweytick, D.8
  • 79
  • 80
    • 12144290656 scopus 로고    scopus 로고
    • Dose-dependent biphasic induction and transcriptional activity of nuclear factor kappa B (NF-kappaB) in EA.hy.926 endothelial cells after low-dose X-irradiation
    • Rodel, F., Hantschel, M., Hildebrandt, G., Schultze-Mosgau, S., Rodel, C., Herrmann, M., Sauer, R., and Voll, R. E. (2004a). Dose-dependent biphasic induction and transcriptional activity of nuclear factor kappa B (NF-kappaB) in EA.hy.926 endothelial cells after low-dose X-irradiation. Int. J. Radiat. Biol. 80, 115-123.
    • (2004) Int. J. Radiat. Biol. , vol.80 , pp. 115-123
    • Rodel, F.1    Hantschel, M.2    Hildebrandt, G.3    Schultze-Mosgau, S.4    Rodel, C.5    Herrmann, M.6    Sauer, R.7    Voll, R.E.8
  • 81
    • 1842765587 scopus 로고    scopus 로고
    • The induction of TGF-beta(1) and NF-kappaB parallels a biphasic time course of leukocyte/endothelial cell adhesion following low-dose X-irradiation
    • Rodel, F., Schaller, U., Schultze-Mosgau, S., Beuscher, H. U., Keilholz, L., Herrmann, M., Voll, R., Sauer, R., and Hildebrandt, G. (2004b). The induction of TGF-beta(1) and NF-kappaB parallels a biphasic time course of leukocyte/endothelial cell adhesion following low-dose X-irradiation. Strahlenther. Onkol. 180, 194-200.
    • (2004) Strahlenther. Onkol. , vol.180 , pp. 194-200
    • Rodel, F.1    Schaller, U.2    Schultze-Mosgau, S.3    Beuscher, H.U.4    Keilholz, L.5    Herrmann, M.6    Voll, R.7    Sauer, R.8    Hildebrandt, G.9
  • 82
    • 0036144547 scopus 로고    scopus 로고
    • Functional and molecular aspects of anti-inflammatory effects of low-dose radiotherapy
    • Rodel, F., Kamprad, F., Sauer, R., and Hildebrandt, G. (2002). Functional and molecular aspects of anti-inflammatory effects of low-dose radiotherapy. Strahlenther. Onkol. 178, 1-9.
    • (2002) Strahlenther. Onkol. , vol.178 , pp. 1-9
    • Rodel, F.1    Kamprad, F.2    Sauer, R.3    Hildebrandt, G.4
  • 83
    • 70749120798 scopus 로고    scopus 로고
    • Activator protein 1 shows a biphasic induction and transcriptional activity after low dose X-irradiation in EA.hy.926 endothelial cells
    • Rodel, F., Keilholz, L., Herrmann, M., Weiss, C., Frey, B., Voll, R., Gaipl, U., and Rodel, C. (2009). Activator protein 1 shows a biphasic induction and transcriptional activity after low dose X-irradiation in EA.hy.926 endothelial cells. Autoimmunity 42, 343-345.
    • (2009) Autoimmunity , vol.42 , pp. 343-345
    • Rodel, F.1    Keilholz, L.2    Herrmann, M.3    Weiss, C.4    Frey, B.5    Voll, R.6    Gaipl, U.7    Rodel, C.8
  • 84
    • 0036690266 scopus 로고    scopus 로고
    • Anti-inflammatory effect of low-dose X-irradiation and the involvement of a TGF-beta1-induced down-regulation of leukocyte/endothelial cell adhesion
    • Roedel, F., Kley, N., Beuscher, H. U., Hildebrandt, G., Keilholz, L., Kern, P., Voll, R., Herrmann, M., and Sauer, R. (2002). Anti-inflammatory effect of low-dose X-irradiation and the involvement of a TGF-beta1-induced down-regulation of leukocyte/endothelial cell adhesion. Int. J. Radiat. Biol. 78, 711-719.
    • (2002) Int. J. Radiat. Biol. , vol.78 , pp. 711-719
    • Roedel, F.1    Kley, N.2    Beuscher, H.U.3    Hildebrandt, G.4    Keilholz, L.5    Kern, P.6    Voll, R.7    Herrmann, M.8    Sauer, R.9
  • 87
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Sauter, B., Albert, M. L., Francisco, L., Larsson, M., Somersan, S., and Bhardwaj, N. (2000). Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J. Exp. Med. 191, 423-434.
    • (2000) J. Exp. Med. , vol.191 , pp. 423-434
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3    Larsson, M.4    Somersan, S.5    Bhardwaj, N.6
  • 88
    • 0036292547 scopus 로고    scopus 로고
    • The effects of low-dose X-irradiation on the oxidative burst in stimulated macrophages
    • Schaue, D., Marples, B., and Trott, K. R. (2002). The effects of low-dose X-irradiation on the oxidative burst in stimulated macrophages. Int. J. Radiat. Biol. 78, 567-576.
    • (2002) Int. J. Radiat. Biol. , vol.78 , pp. 567-576
    • Schaue, D.1    Marples, B.2    Trott, K.R.3
  • 91
    • 80655127833 scopus 로고    scopus 로고
    • Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages
    • Schildkopf, P., Frey, B., Ott, O. J., Rubner, Y., Multhoff, G., Sauer, R., Fietkau, R., and Gaipl, U. S. (2011). Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages. Radiother. Oncol. 101, 109-115.
    • (2011) Radiother. Oncol. , vol.101 , pp. 109-115
    • Schildkopf, P.1    Frey, B.2    Ott, O.J.3    Rubner, Y.4    Multhoff, G.5    Sauer, R.6    Fietkau, R.7    Gaipl, U.S.8
  • 92
    • 0041626198 scopus 로고    scopus 로고
    • Hyperthermia improves cellular immune response to human hepatocellular carcinoma subsequent to co-culture with tumor lysate pulsed dendritic cells
    • Schueller, G., Stift, A., Friedl, J., Dubsky, P., Bachleitner-Hofmann, T., Benkoe, T., Jakesz, R., and Gnant, M. (2003). Hyperthermia improves cellular immune response to human hepatocellular carcinoma subsequent to co-culture with tumor lysate pulsed dendritic cells. Int. J. Oncol. 22, 1397-1402.
    • (2003) Int. J. Oncol. , vol.22 , pp. 1397-1402
    • Schueller, G.1    Stift, A.2    Friedl, J.3    Dubsky, P.4    Bachleitner-Hofmann, T.5    Benkoe, T.6    Jakesz, R.7    Gnant, M.8
  • 94
    • 0028898695 scopus 로고
    • The abscopal effect and chronic lymphocytic leukemia
    • Sham, R. L. (1995). The abscopal effect and chronic lymphocytic leukemia. Am. J. Med. 98, 307-308.
    • (1995) Am. J. Med. , vol.98 , pp. 307-308
    • Sham, R.L.1
  • 95
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran, V., Ikeda, H., Bruce, A. T., White, J. M., Swanson, P. E., Old, L. J., and Schreiber, R. D. (2001). IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410, 1107-1111.
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 97
    • 39749126854 scopus 로고    scopus 로고
    • Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha
    • Shiraishi, K., Ishiwata, Y., Nakagawa, K., Yokochi, S., Taruki, C., Akuta, T., Ohtomo, K., Matsushima, K., Tamatani, T., and Kanegasaki, S. (2008). Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha. Clin. Cancer Res. 14, 1159-1166.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1159-1166
    • Shiraishi, K.1    Ishiwata, Y.2    Nakagawa, K.3    Yokochi, S.4    Taruki, C.5    Akuta, T.6    Ohtomo, K.7    Matsushima, K.8    Tamatani, T.9    Kanegasaki, S.10
  • 98
    • 0035500779 scopus 로고    scopus 로고
    • Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells
    • Somersan, S., Larsson, M., Fonteneau, J. F., Basu, S., Srivastava, P., and Bhardwaj, N. (2001). Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells. J. Immunol. 167, 4844-4852.
    • (2001) J. Immunol. , vol.167 , pp. 4844-4852
    • Somersan, S.1    Larsson, M.2    Fonteneau, J.F.3    Basu, S.4    Srivastava, P.5    Bhardwaj, N.6
  • 99
    • 67349283923 scopus 로고    scopus 로고
    • Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells
    • Stangl, S., Gross, C., Pockley, A. G., Asea, A. A., and Multhoff, G. (2008). Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells. Cell Stress Chaperones 13, 221-230.
    • (2008) Cell Stress Chaperones , vol.13 , pp. 221-230
    • Stangl, S.1    Gross, C.2    Pockley, A.G.3    Asea, A.A.4    Multhoff, G.5
  • 100
    • 77950829391 scopus 로고    scopus 로고
    • Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy
    • Takeshima, T., Chamoto, K., Wakita, D., Ohkuri, T., Togashi, Y., Shirato, H., Kitamura, H., and Nishimura, T. (2010). Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy. Cancer Res. 70, 2697-2706.
    • (2010) Cancer Res. , vol.70 , pp. 2697-2706
    • Takeshima, T.1    Chamoto, K.2    Wakita, D.3    Ohkuri, T.4    Togashi, Y.5    Shirato, H.6    Kitamura, H.7    Nishimura, T.8
  • 101
    • 59649097039 scopus 로고    scopus 로고
    • 0.5 Gy gamma radiation suppresses production of TNF-alpha through up-regulation of MKP-1 in mouse macrophage RAW264.7 cells
    • Tsukimoto, M., Homma, T., Mutou, Y., and Kojima, S. (2009). 0.5 Gy gamma radiation suppresses production of TNF-alpha through up-regulation of MKP-1 in mouse macrophage RAW264.7 cells. Radiat. Res. 171, 219-224.
    • (2009) Radiat. Res. , vol.171 , pp. 219-224
    • Tsukimoto, M.1    Homma, T.2    Mutou, Y.3    Kojima, S.4
  • 105
    • 44849084963 scopus 로고    scopus 로고
    • Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages
    • Vega, V. L., Rodriguez-Silva, M., Frey, T., Gehrmann, M., Diaz, J. C., Steinem, C., Multhoff, G., Arispe, N., and De Maio, A. (2008). Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages. J. Immunol. 180, 4299-4307.
    • (2008) J. Immunol. , vol.180 , pp. 4299-4307
    • Vega, V.L.1    Rodriguez-Silva, M.2    Frey, T.3    Gehrmann, M.4    Diaz, J.C.5    Steinem, C.6    Multhoff, G.7    Arispe, N.8    De Maio, A.9
  • 107
    • 0028191375 scopus 로고
    • Control of nitric oxide synthase expression by transforming growth factor-beta: implications for homeostasis
    • Vodovotz, Y., and Bogdan, C. (1994). Control of nitric oxide synthase expression by transforming growth factor-beta: implications for homeostasis. Prog. Growth Factor Res. 5, 341-351.
    • (1994) Prog. Growth Factor Res. , vol.5 , pp. 341-351
    • Vodovotz, Y.1    Bogdan, C.2
  • 109
    • 33745106605 scopus 로고    scopus 로고
    • Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma
    • Wersall, P. J., Blomgren, H., Pisa, P., Lax, I., Kalkner, K. M., and Svedman, C. (2006). Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma. Acta Oncol. 45, 493-497.
    • (2006) Acta Oncol. , vol.45 , pp. 493-497
    • Wersall, P.J.1    Blomgren, H.2    Pisa, P.3    Lax, I.4    Kalkner, K.M.5    Svedman, C.6
  • 110
    • 4143103624 scopus 로고    scopus 로고
    • Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination
    • Wheeler, C. J., Das, A., Liu, G., Yu, J. S., and Black, K. L. (2004). Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination. Clin. Cancer Res. 10, 5316-5326.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5316-5326
    • Wheeler, C.J.1    Das, A.2    Liu, G.3    Yu, J.S.4    Black, K.L.5
  • 112
    • 78649952821 scopus 로고    scopus 로고
    • Integration of host-related signatures with cancer cell-derived predictors for the optimal management of anticancer chemotherapy
    • Zitvogel, L., Kepp, O., Aymeric, L., Ma, Y., Locher, C., Delahaye, N. F., Andre, F., and Kroemer, G. (2010). Integration of host-related signatures with cancer cell-derived predictors for the optimal management of anticancer chemotherapy. Cancer Res. 70, 9538-9543.
    • (2010) Cancer Res. , vol.70 , pp. 9538-9543
    • Zitvogel, L.1    Kepp, O.2    Aymeric, L.3    Ma, Y.4    Locher, C.5    Delahaye, N.F.6    Andre, F.7    Kroemer, G.8


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