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Volumn 8, Issue 3, 2013, Pages 170-175

How to best measure HIV reservoirs?

Author keywords

HIV latency; markers of HIV reservoirs; quantification

Indexed keywords

CD4 ANTIGEN; VIRUS DNA; VIRUS RNA;

EID: 84876415088     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0b013e32835fc619     Document Type: Review
Times cited : (42)

References (57)
  • 1
    • 62249095476 scopus 로고    scopus 로고
    • The challenge of finding a cure for HIV infection
    • Richman DD, Margolis DM, Delaney M, et al. The challenge of finding a cure for HIV infection. Science 2009; 323:1304-1307.
    • (2009) Science , vol.323 , pp. 1304-1307
    • Richman, D.D.1    Margolis, D.M.2    Delaney, M.3
  • 2
    • 77950537810 scopus 로고    scopus 로고
    • HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
    • Buzon MJ, Massanella M, Llibre JM, et al. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects. Nat Med 2010; 16:460-465.
    • (2010) Nat Med , vol.16 , pp. 460-465
    • Buzon, M.J.1    Massanella, M.2    Llibre, J.M.3
  • 3
    • 79952116429 scopus 로고    scopus 로고
    • A high HIV DNA level in PBMCs at antiretroviral treatment interruption predicts a shorter time to treatment resumption, independently of the CD4 nadir
    • Piketty C, Weiss L, Assoumou L, et al. A high HIV DNA level in PBMCs at antiretroviral treatment interruption predicts a shorter time to treatment resumption, independently of the CD4 nadir. J Med Virol 2010; 82:1819-1828.
    • (2010) J Med Virol , vol.82 , pp. 1819-1828
    • Piketty, C.1    Weiss, L.2    Assoumou, L.3
  • 4
    • 84857718947 scopus 로고    scopus 로고
    • Switching virally suppressed, treatment-experienced patients to a raltegravir-containing regimen does not alter levels of HIV-1 DNA
    • Lam YM, McBride KL, Amin J, et al. Switching virally suppressed, treatment-experienced patients to a raltegravir-containing regimen does not alter levels of HIV-1 DNA. PLoS One 2012; 7:e31990.
    • (2012) PLoS One , vol.7
    • Lam, Y.M.1    McBride, K.L.2    Amin, J.3
  • 5
    • 77954633050 scopus 로고    scopus 로고
    • HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals
    • Trono D, Van Lint C, Rouzioux C, et al. HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals. Science 2010; 329:174-180.
    • (2010) Science , vol.329 , pp. 174-180
    • Trono, D.1    Van Lint, C.2    Rouzioux, C.3
  • 6
    • 79954442770 scopus 로고    scopus 로고
    • Introduction: Challenges to finding a cure for HIV infection
    • Richman DD. Introduction: challenges to finding a cure for HIV infection. Curr Opin HIV AIDS 2011; 6:1-3.
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 1-3
    • Richman, D.D.1
  • 7
    • 78549245806 scopus 로고    scopus 로고
    • Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
    • Yukl SA, Shergill AK, McQuaid K, et al. Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS 2010; 24:2451-2460.
    • (2010) AIDS , vol.24 , pp. 2451-2460
    • Yukl, S.A.1    Shergill, A.K.2    McQuaid, K.3
  • 8
    • 84857479601 scopus 로고    scopus 로고
    • Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antire-troviral therapy
    • Zeng M, Southern PJ, Reilly CS, et al. Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antire-troviral therapy. PLoS Pathog 2012; 8:e1002437.
    • (2012) PLoS Pathog , vol.8
    • Zeng, M.1    Southern, P.J.2    Reilly, C.S.3
  • 9
    • 4644342929 scopus 로고    scopus 로고
    • CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
    • Brenchley JM, Schacker TW, Ruff LE, et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004; 200:749-759.
    • (2004) J Exp Med , vol.200 , pp. 749-759
    • Brenchley, J.M.1    Schacker, T.W.2    Ruff, L.E.3
  • 10
    • 17844374605 scopus 로고    scopus 로고
    • + T cells in multiple tissues during acute SIV infection
    • + T cells in multiple tissues during acute SIV infection. Nature 2005; 434:1093-1097.
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3
  • 11
    • 77649117525 scopus 로고    scopus 로고
    • Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS
    • North TW, Higgins J, Deere JD, et al. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. J Virol 2010; 84:2913-2922.
    • (2010) J Virol , vol.84 , pp. 2913-2922
    • North, T.W.1    Higgins, J.2    Deere, J.D.3
  • 12
    • 68349139711 scopus 로고    scopus 로고
    • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    • Chomont N, El-Far M, Ancuta P, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 2009; 15:893-900.
    • (2009) Nat Med , vol.15 , pp. 893-900
    • Chomont, N.1    El-Far, M.2    Ancuta, P.3
  • 13
    • 84860255621 scopus 로고    scopus 로고
    • Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells
    • Descours B, Avettand-Fenoel V, Blanc C, et al. Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells. Clin Infect Dis 2012; 54:1495-1503.
    • (2012) Clin Infect Dis , vol.54 , pp. 1495-1503
    • Descours, B.1    Avettand-Fenoel, V.2    Blanc, C.3
  • 14
    • 75649145950 scopus 로고    scopus 로고
    • Immunologic and virologic events in early HIV infection predict subsequent rate of progression
    • Ganesan A, Chattopadhyay PK, Brodie TM, et al. Immunologic and virologic events in early HIV infection predict subsequent rate of progression. J Infect Dis 2010; 201:272-284.
    • (2010) J Infect Dis , vol.201 , pp. 272-284
    • Ganesan, A.1    Chattopadhyay, P.K.2    Brodie, T.M.3
  • 15
    • 67650550767 scopus 로고    scopus 로고
    • Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: Implications for treatment of latent infection
    • Reuse S, Calao M, Kabeya K, et al. Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PloS One 2009; 4:e6093.
    • (2009) PloS One , vol.4
    • Reuse, S.1    Calao, M.2    Kabeya, K.3
  • 16
    • 84864286769 scopus 로고    scopus 로고
    • Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients
    • Bouchat S, Gatot JS, Kabeya K, et al. Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients. AIDS 2012; 26:1473-1482.
    • (2012) AIDS , vol.26 , pp. 1473-1482
    • Bouchat, S.1    Gatot, J.S.2    Kabeya, K.3
  • 18
    • 84873472629 scopus 로고    scopus 로고
    • Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
    • Eriksson S, Graf EH, Dahl V, et al. Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies. PloS Pathog 2013; 9:e1003174.
    • (2013) PloS Pathog , vol.9
    • Eriksson, S.1    Graf, E.H.2    Dahl, V.3
  • 19
    • 79960569795 scopus 로고    scopus 로고
    • Majority of CD4+ T cells from peripheral blood of HIV-1-infected individuals contain only one HIV DNA molecule
    • Josefsson L, King MS, Makitalo B, et al. Majority of CD4+ T cells from peripheral blood of HIV-1-infected individuals contain only one HIV DNA molecule. Proc Natl Acad Sci USA 2011; 108:11199-11204.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 11199-11204
    • Josefsson, L.1    King, M.S.2    Makitalo, B.3
  • 20
    • 78149441721 scopus 로고    scopus 로고
    • Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection
    • Schmid A, Gianella S, von Wyl V, et al. Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection. PloS One 2010; 5:e13310.
    • (2010) PloS One , vol.5
    • Schmid, A.1    Gianella, S.2    Von Wyl, V.3
  • 21
    • 77952580564 scopus 로고    scopus 로고
    • Despite being highly diverse, immuno-virological status strongly correlates with clinical symptoms during primary HIV-1 infection: A cross-sectional study based on 674 patients enrolled in the ANRS CO 06 PRIMO cohort
    • Ghosn J, Deveau C, Chaix ML, et al. Despite being highly diverse, immuno-virological status strongly correlates with clinical symptoms during primary HIV-1 infection: a cross-sectional study based on 674 patients enrolled in the ANRS CO 06 PRIMO cohort. J Antimicrob Chemother 2010; 65:741-748.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 741-748
    • Ghosn, J.1    Deveau, C.2    Chaix, M.L.3
  • 22
    • 20244376915 scopus 로고    scopus 로고
    • Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1
    • Strain MC, Little SJ, Daar ES, et al. Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis 2005; 191:1410-1418.
    • (2005) J Infect Dis , vol.191 , pp. 1410-1418
    • Strain, M.C.1    Little, S.J.2    Daar, E.S.3
  • 24
    • 84866498069 scopus 로고    scopus 로고
    • Redefining the viral reservoirs that prevent HIV-1 eradication
    • Eisele E, Siliciano RF. Redefining the viral reservoirs that prevent HIV-1 eradication. Immunity 2012; 37:377-388.
    • (2012) Immunity , vol.37 , pp. 377-388
    • Eisele, E.1    Siliciano, R.F.2
  • 25
    • 84866707088 scopus 로고    scopus 로고
    • The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients
    • Vallejo A, Gutierrez C, Hernandez-Novoa B, et al. The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients. AIDS 2012; 26:1885-1894.
    • (2012) AIDS , vol.26 , pp. 1885-1894
    • Vallejo, A.1    Gutierrez, C.2    Hernandez-Novoa, B.3
  • 26
    • 46349093367 scopus 로고    scopus 로고
    • HIV-1 DNA for the measurement of the HIV reservoir is predictive of disease progression in seroconverters whatever the mode of result expression is
    • Avettand-Fenoel V, Boufassa F, Galimand J, et al. HIV-1 DNA for the measurement of the HIV reservoir is predictive of disease progression in seroconverters whatever the mode of result expression is. J Clin Virol 2008; 42:399-404.
    • (2008) J Clin Virol , vol.42 , pp. 399-404
    • Avettand-Fenoel, V.1    Boufassa, F.2    Galimand, J.3
  • 27
    • 79957966626 scopus 로고    scopus 로고
    • Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy
    • Chun TW, Murray D, Justement JS, et al. Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy. J Infect Dis 2011; 204:135-138.
    • (2011) J Infect Dis , vol.204 , pp. 135-138
    • Chun, T.W.1    Murray, D.2    Justement, J.S.3
  • 28
    • 84864934043 scopus 로고    scopus 로고
    • Effect of histone deacetylase inhibitors on HIV production in latently infected, resting CD4(+) T cells from infected individuals receiving effective antiretroviral therapy
    • Blazkova J, Chun TW, Belay BW, et al. Effect of histone deacetylase inhibitors on HIV production in latently infected, resting CD4(+) T cells from infected individuals receiving effective antiretroviral therapy. J Infect Dis 2012; 206:765-769.
    • (2012) J Infect Dis , vol.206 , pp. 765-769
    • Blazkova, J.1    Chun, T.W.2    Belay, B.W.3
  • 29
    • 84869020196 scopus 로고    scopus 로고
    • Low-level detection and quantitation of cellular HIV-1 DNA and 2-LTR circles using droplet digital PCR
    • Henrich TJ, Gallien S, Li JZ, et al. Low-level detection and quantitation of cellular HIV-1 DNA and 2-LTR circles using droplet digital PCR. J Virol Methods 2012; 186:68-72.
    • (2012) J Virol Methods , vol.186 , pp. 68-72
    • Henrich, T.J.1    Gallien, S.2    Li, J.Z.3
  • 30
    • 0036838605 scopus 로고    scopus 로고
    • A sensitive, quantitative assay for human immunodeficiency virus type 1 integration
    • O'Doherty U, Swiggard WJ, Jeyakumar D, et al. A sensitive, quantitative assay for human immunodeficiency virus type 1 integration. J Virol 2002; 76:10942-10950.
    • (2002) J Virol , vol.76 , pp. 10942-10950
    • O'Doherty, U.1    Swiggard, W.J.2    Jeyakumar, D.3
  • 31
    • 64649087732 scopus 로고    scopus 로고
    • Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR
    • Liszewski MK, Yu JJ, O'Doherty U. Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR. Methods 2009; 47:254-260.
    • (2009) Methods , vol.47 , pp. 254-260
    • Liszewski, M.K.1    Yu, J.J.2    O'Doherty, U.3
  • 32
    • 48949097519 scopus 로고    scopus 로고
    • A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients
    • Yu JJ, Wu TL, Liszewski MK, et al. A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients. Virology 2008; 379:78-86.
    • (2008) Virology , vol.379 , pp. 78-86
    • Yu, J.J.1    Wu, T.L.2    Liszewski, M.K.3
  • 33
    • 79952204267 scopus 로고    scopus 로고
    • Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure
    • Sharkey M, Babic DZ, Greenough T, et al. Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure. PLoS Pathog 2011; 7:e1001303.
    • (2011) PLoS Pathog , vol.7
    • Sharkey, M.1    Babic, D.Z.2    Greenough, T.3
  • 34
    • 38649136321 scopus 로고    scopus 로고
    • Virologic determinants of success after structured treatment interruptions of antiretrovirals in acute HIV-1 infection
    • Lewin SR, Murray JM, Solomon A, et al. Virologic determinants of success after structured treatment interruptions of antiretrovirals in acute HIV-1 infection. J Acquir Immune Defic Syndr 2008; 47:140-147.
    • (2008) J Acquir Immune Defic Syndr , vol.47 , pp. 140-147
    • Lewin, S.R.1    Murray, J.M.2    Solomon, A.3
  • 35
    • 84862275684 scopus 로고    scopus 로고
    • Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards
    • Murray JM, McBride K, Boesecke C, et al. Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards. AIDS 2012; 26:543-550.
    • (2012) AIDS , vol.26 , pp. 543-550
    • Murray, J.M.1    McBride, K.2    Boesecke, C.3
  • 36
    • 84864203255 scopus 로고    scopus 로고
    • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
    • Archin NM, Liberty AL, Kashuba AD, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 2012; 487:482-485.
    • (2012) Nature , vol.487 , pp. 482-485
    • Archin, N.M.1    Liberty, A.L.2    Kashuba, A.D.3
  • 37
    • 77956856393 scopus 로고    scopus 로고
    • The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial
    • Gandhi RT, Zheng L, Bosch RJ, et al. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med 2010; 7:e1000321.
    • (2010) PLoS Med , vol.7
    • Gandhi, R.T.1    Zheng, L.2    Bosch, R.J.3
  • 38
    • 10744228049 scopus 로고    scopus 로고
    • New real-time reverse transcrip-tase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma
    • Palmer S, Wiegand AP, Maldarelli F, et al. New real-time reverse transcrip-tase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 2003; 41:4531-4536.
    • (2003) J Clin Microbiol , vol.41 , pp. 4531-4536
    • Palmer, S.1    Wiegand, A.P.2    Maldarelli, F.3
  • 39
    • 41649083599 scopus 로고    scopus 로고
    • Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
    • Palmer S, Maldarelli F, Wiegand A, et al. Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy. Proc Natl Acad Sci USA 2008; 105:3879-3884.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3879-3884
    • Palmer, S.1    Maldarelli, F.2    Wiegand, A.3
  • 40
    • 84891731687 scopus 로고    scopus 로고
    • Predictors of residual viremia in patients on long-term suppressive antiretroviral therapy
    • Zheng L, Bosch RJ, Chan ES, et al. Predictors of residual viremia in patients on long-term suppressive antiretroviral therapy. Antivir Ther 2012; 20:.
    • (2012) Antivir Ther , pp. 20
    • Zheng, L.1    Bosch, R.J.2    Chan, E.S.3
  • 41
    • 61749103775 scopus 로고    scopus 로고
    • LTR real-time PCR for HIV-1 DNA quantitation in blood cells for early diagnosis in infants born to ser-opositive mothers treated in HAART area (ANRS CO 01)
    • Avettand-Fenoel V, Chaix ML, Blanche S, et al. LTR real-time PCR for HIV-1 DNA quantitation in blood cells for early diagnosis in infants born to ser-opositive mothers treated in HAART area (ANRS CO 01). J Med Virol 2009; 81:217-223.
    • (2009) J Med Virol , vol.81 , pp. 217-223
    • Avettand-Fenoel, V.1    Chaix, M.L.2    Blanche, S.3
  • 42
    • 20844452242 scopus 로고    scopus 로고
    • Early levels of HIV-1 DNA in peripheral blood mononuclear cells are predictive of disease progression independently of HIV-1 RNA levels and CD4+T cell counts
    • Rouzioux C, Hubert JB, Burgard M, et al. Early levels of HIV-1 DNA in peripheral blood mononuclear cells are predictive of disease progression independently of HIV-1 RNA levels and CD4+T cell counts. JInfect Dis 2005; 192:46-55.
    • (2005) JInfect Dis , vol.192 , pp. 46-55
    • Rouzioux, C.1    Hubert, J.B.2    Burgard, M.3
  • 43
    • 33144485618 scopus 로고    scopus 로고
    • CD4 cell count and HIV DNA level are independent predictors of disease progression after primary HIV type 1 infection in untreated patients
    • Goujard C, Bonarek M, Meyer L, et al. CD4 cell count and HIV DNA level are independent predictors of disease progression after primary HIV type 1 infection in untreated patients. Clin Infect Dis 2006; 42:709-715.
    • (2006) Clin Infect Dis , vol.42 , pp. 709-715
    • Goujard, C.1    Bonarek, M.2    Meyer, L.3
  • 44
    • 47049105870 scopus 로고    scopus 로고
    • HIV-1 DNA in peripheral blood mononuclear cells is strongly associated with HIV-1 disease progression in recently infected West African adults
    • Minga AK, Anglaret X, d' Aquin Toni T, et al. HIV-1 DNA in peripheral blood mononuclear cells is strongly associated with HIV-1 disease progression in recently infected West African adults. J Acquir Immune Defic Syndr 2008; 48:350-354.
    • (2008) J Acquir Immune Defic Syndr , vol.48 , pp. 350-354
    • Minga, A.K.1    Anglaret, X.2    D'Aquin Toni, T.3
  • 45
    • 84859186406 scopus 로고    scopus 로고
    • Impact of HIV type 1 DNA levels on spontaneous disease progression: A meta-analysis
    • Tsiara CG, Nikolopoulos GK, Bagos PG, et al. Impact of HIV type 1 DNA levels on spontaneous disease progression: a meta-analysis. AIDS Res Hum Retroviruses 2012; 28:366-373.
    • (2012) AIDS Res Hum Retroviruses , vol.28 , pp. 366-373
    • Tsiara, C.G.1    Nikolopoulos, G.K.2    Bagos, P.G.3
  • 46
    • 77954752400 scopus 로고    scopus 로고
    • Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers
    • Julg B, Pereyra F, Buzon MJ, et al. Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers. Clin Infect Dis 2010; 51:233-238.
    • (2010) Clin Infect Dis , vol.51 , pp. 233-238
    • Julg, B.1    Pereyra, F.2    Buzon, M.J.3
  • 47
    • 79952072932 scopus 로고    scopus 로고
    • Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART
    • Graf EH, Mexas AM, Yu JJ, et al. Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART. PLoS Pathog 2011; 7:e1001300.
    • (2011) PLoS Pathog , vol.7
    • Graf, E.H.1    Mexas, A.M.2    Yu, J.J.3
  • 49
    • 25444471257 scopus 로고    scopus 로고
    • HIV controllers: A homogeneous group of HIV-1-infected patients with spontaneous control of viral replication
    • Lambotte O, Boufassa F, Madec Y, et al. HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication. Clin Infect Dis 2005; 41:1053-1056.
    • (2005) Clin Infect Dis , vol.41 , pp. 1053-1056
    • Lambotte, O.1    Boufassa, F.2    Madec, Y.3
  • 50
    • 77953916829 scopus 로고    scopus 로고
    • Long-term immunoviro-logic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection
    • Hocqueloux L, Prazuck T, Avettand-Fenoel V, et al. Long-term immunoviro-logic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection. AIDS 2010; 24:1598-1601.
    • (2010) AIDS , vol.24 , pp. 1598-1601
    • Hocqueloux, L.1    Prazuck, T.2    Avettand-Fenoel, V.3
  • 51
    • 84865717158 scopus 로고    scopus 로고
    • HIV-1 control after transient antire-troviral treatment initiated in primary infection: Role of patient characteristics and effect of therapy
    • Goujard C, Girault I, Rouzioux C, et al. HIV-1 control after transient antire-troviral treatment initiated in primary infection: role of patient characteristics and effect of therapy. Antivir Ther 2012; 17:1001-1009.
    • (2012) Antivir Ther , vol.17 , pp. 1001-1009
    • Goujard, C.1    Girault, I.2    Rouzioux, C.3
  • 52
    • 84866130614 scopus 로고    scopus 로고
    • Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion
    • Lodi S, Meyer L, Kelleher AD, et al. Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion. Arch Intern Med 2012; 172:1252-1255.
    • (2012) Arch Intern Med , vol.172 , pp. 1252-1255
    • Lodi, S.1    Meyer, L.2    Kelleher, A.D.3
  • 53
    • 84875985311 scopus 로고    scopus 로고
    • Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy. ANRS VISCONTI study 2013
    • ANRS VISCONTI Study Group, doi. 10.1371/journal.ppat.1003211
    • Saez-Cirion A, Bacchus C, Hocqueloux L, et al. ANRS VISCONTI Study Group. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy. ANRS VISCONTI study 2013. PLoS Pathog doi. 10.1371/journal.ppat.1003211.
    • PLoS Pathog
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3
  • 54
    • 84870250032 scopus 로고    scopus 로고
    • Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials
    • Mexas AM, Graf EH, Pace MJ, et al. Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials. AIDS 2012; 26:2295-2306.
    • (2012) AIDS , vol.26 , pp. 2295-2306
    • Mexas, A.M.1    Graf, E.H.2    Pace, M.J.3
  • 55
    • 78649442148 scopus 로고    scopus 로고
    • Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs
    • Agosto LM, Liszewski MK, Mexas A, et al. Patients on HAART often have an excess of unintegrated HIV DNA: implications for monitoring reservoirs. Virology 2011; 409:46-53.
    • (2011) Virology , vol.409 , pp. 46-53
    • Agosto, L.M.1    Liszewski, M.K.2    Mexas, A.3
  • 56
    • 77950223662 scopus 로고    scopus 로고
    • The role of HIV-DNA testing in clinical practice
    • d'Ettorre G, Zaffiri L, Ceccarelli G, et al. The role of HIV-DNA testing in clinical practice. New Microbiol 2010; 33: 1-11.
    • (2010) New Microbiol , vol.33 , pp. 1-11
    • D'Ettorre, G.1    Zaffiri, L.2    Ceccarelli, G.3
  • 57
    • 60549090253 scopus 로고    scopus 로고
    • Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009; 360:692-698.
    • (2009) N Engl J Med , vol.360 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3


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