-
1
-
-
77950218212
-
Prevalence of viral infection detected by PCR and RT-PCR in patients with acute exacerbation of COPD: A systematic review
-
Mohan, A. et al. Prevalence of viral infection detected by PCR and RT-PCR in patients with acute exacerbation of COPD: a systematic review. Respirology 15, 536-542 (2010).
-
(2010)
Respirology
, vol.15
, pp. 536-542
-
-
Mohan, A.1
-
2
-
-
0037253901
-
Respiratory viruses in exacerbations of chronic obstructive pulmonary disease requiring hospitalisation: A case-control study
-
Rohde, G. et al. Respiratory viruses in exacerbations of chronic obstructive pulmonary disease requiring hospitalisation: a case-control study. Thorax 58, 37-42 (2003).
-
(2003)
Thorax
, vol.58
, pp. 37-42
-
-
Rohde, G.1
-
3
-
-
0035509117
-
Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease
-
Seemungal, T. et al. Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 164, 1618-1623 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
, pp. 1618-1623
-
-
Seemungal, T.1
-
4
-
-
70249120405
-
Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice
-
towell, N. C. et al. Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice. Respir. Res. 10, 43 (2009).
-
(2009)
Respir. Res.
, vol.1
, pp. 43
-
-
Towell, N.C.1
-
5
-
-
31144442984
-
Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells
-
Groskreutz, D. J., Monick, M. M., Powers, L. S., Yarovinsky, T. O., Look, D. C. & Hunninghake, G. W. Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells. J. Immunol. 176, 1733-1740 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 1733-1740
-
-
Groskreutz, D.J.1
Monick, M.M.2
Powers, L.S.3
Yarovinsky, T.O.4
Look, D.C.5
Hunninghake, G.W.6
-
6
-
-
33947206046
-
Cutting edge: Infl uenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells
-
Le Goffi c, R. et al. Cutting edge: infl uenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells. J. Immunol. 178, 3368-3372 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 3368-3372
-
-
Le Goffic, R.1
-
7
-
-
79958062793
-
MDA5 and TLR3 initiate pro-infl ammatory signaling pathways leading to rhinovirus-induced airways infl ammation and hyperresponsiveness
-
Wang, Q. et al. MDA5 and TLR3 initiate pro-infl ammatory signaling pathways leading to rhinovirus-induced airways infl ammation and hyperresponsiveness. PLoS Pathogens 7, e1002070 (2011).
-
(2011)
PLoS Pathogens
, vol.7
-
-
Wang, Q.1
-
8
-
-
48749097634
-
Cigarette smoke selectively enhances viral PAMP-and virus-induced pulmonary innate immune and remodeling responses in mice
-
Kang, M. J. et al. Cigarette smoke selectively enhances viral PAMP-and virus-induced pulmonary innate immune and remodeling responses in mice. J. Clin. Invest. 118, 2771-2784 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2771-2784
-
-
Kang, M.J.1
-
9
-
-
85185114338
-
-
GSVA-The Gene Set Variation Analysis Package Accessed Date Accessed 2011 Accessed
-
GSVA-The Gene Set Variation Analysis Package. http://www.bioconductor. org/packages/2.8/bioc/html/GSVA.html 2011, Accessed Date Accessed 2011 Accessed.
-
-
-
-
10
-
-
67749112023
-
Deconvolution of blood microarray data identifi es cellular activation patterns in systemic lupus erythematosus
-
Abbas, A. R., Wolslegel, K., Seshasayee, D., Modrusan, Z. & Clark, H. F. Deconvolution of blood microarray data identifi es cellular activation patterns in systemic lupus erythematosus. PloS One 4, e6098 (2009).
-
(2009)
PloS One
, vol.4
-
-
Abbas, A.R.1
Wolslegel, K.2
Seshasayee, D.3
Modrusan, Z.4
Clark, H.F.5
-
11
-
-
46749152178
-
A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
-
Chaussabel, D. et al. A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 29, 150-164 (2008).
-
(2008)
Immunity
, vol.29
, pp. 150-164
-
-
Chaussabel, D.1
-
12
-
-
34250197581
-
C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists
-
Chao, J. et al. C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists. Bioorg. Med. Chem. Lett. 17, 3778-3783 (2007).
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 3778-3783
-
-
Chao, J.1
-
13
-
-
13044256383
-
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
Baba, M. et al. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc. Natl. Acad. Sci. USA 96, 5698-5703 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
-
14
-
-
9744250109
-
Emphysema lung tissue gene expression profi ling
-
Golpon, H. A. et al. Emphysema lung tissue gene expression profi ling. Am. J. Respir. Cell Mol. Biol. 31, 595-600 (2004).
-
(2004)
Am. J. Respir. Cell Mol. Biol.
, vol.31
, pp. 595-600
-
-
Golpon, H.A.1
-
15
-
-
67650721786
-
Gene expression profi les of acute exacerbations of idiopathic pulmonary fi brosis
-
Konishi, K. et al. Gene expression profi les of acute exacerbations of idiopathic pulmonary fi brosis. Am. J. Respir. Crit. Care Med. 180, 167-175 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 167-175
-
-
Konishi, K.1
-
16
-
-
46749150361
-
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections
-
Kohlmeier, J. E. et al. The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections. Immunity 29, 101-113 (2008).
-
(2008)
Immunity
, vol.29
, pp. 101-113
-
-
Kohlmeier, J.E.1
-
17
-
-
0021013562
-
Natural killer cells in mouse lung: Surface phenotype, target preference, and response to local infl uenza virus infection
-
Stein-Streilein, J., Bennett, M., Mann, D. & Kumar, V. Natural killer cells in mouse lung: surface phenotype, target preference, and response to local infl uenza virus infection. J. Immunol. 131, 2699-2704 (1983).
-
(1983)
J. Immunol.
, vol.131
, pp. 2699-2704
-
-
Stein-Streilein, J.1
Bennett, M.2
Mann, D.3
Kumar, V.4
-
18
-
-
79959556964
-
Cutting edge: IL-15- independent maintenance of mucosally generated memory CD8 T cells
-
Verbist, K. C., Field, M. B. & Klonowski, K. D. Cutting edge: IL-15- independent maintenance of mucosally generated memory CD8 T cells. J. Immunol. 186, 6667-6671 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 6667-6671
-
-
Verbist, K.C.1
Field, M.B.2
Klonowski, K.D.3
-
19
-
-
35348917816
-
CXCR2 is required for neutrophil recruitment to the lung during infl uenza virus infection, but is not essential for viral clearance
-
Wareing, M. D., Shea, A. L., Inglis, C A., Dias, P. B. & Sarawar, S. R. CXCR2 is required for neutrophil recruitment to the lung during infl uenza virus infection, but is not essential for viral clearance. Viral. Immunol. 20, 369-378 (2007)
-
(2007)
Viral. Immunol.
, vol.20
, pp. 369-378
-
-
Wareing, M.D.1
Shea, A.L.2
Inglis, C.A.3
Dias, P.B.4
Sarawar, S.R.5
-
20
-
-
80053314504
-
Lactobacilli and bifi dobacteria induce differential interferon-beta profi les in dendritic cells
-
Weiss, G., Christensen, H. R., Zeuthen, L H., Vogensen, F. K., Jakobsen, M & Frokiaer, H. Lactobacilli and bifi dobacteria induce differential interferon-beta profi les in dendritic cells. Cytokine 56, 520-530 (2011)
-
(2011)
Cytokine
, vol.56
, pp. 520-530
-
-
Weiss, G.1
Christensen, H.R.2
Zeuthen, L.H.3
Vogensen, F.K.4
Jakobsen, M.5
Frokiaer, H.6
-
21
-
-
33645518610
-
Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors
-
Piqueras, B., Connolly, J., Freitas, H, Palucka, A. K. & Banchereau, J Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors. Blood 107, 2613-2618 (2006).
-
(2006)
Blood
, vol.107
, pp. 2613-2618
-
-
Piqueras, B.1
Connolly, J.2
Freitas, H.3
Palucka, A.K.4
Banchereau, J.5
-
22
-
-
30744447910
-
CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection
-
Tyner, J. W. et al. CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection. Nat. Med. 11, 1180-1187 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. 1180-1187
-
-
Tyner, J.W.1
-
23
-
-
44949257271
-
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
-
Kim, E. Y et al. Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat. Med. 14, 633-640 (2008)
-
(2008)
Nat. Med.
, vol.14
, pp. 633-640
-
-
Kim, E.Y.1
-
24
-
-
77952708025
-
CXCR2 is required for neutrophilic airway infl ammation and hyperresponsiveness in a mouse model of human rhinovirus infection
-
Nagarkar, D. R. et al. CXCR2 is required for neutrophilic airway infl ammation and hyperresponsiveness in a mouse model of human rhinovirus infection. J. Immunol. 183, 6698-6707 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 6698-6707
-
-
Nagarkar, D.R.1
-
25
-
-
38949170602
-
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway infl ammation
-
Bartlett, N. W. et al. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway infl ammation. Nat. Med. 14, 199-204 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 199-204
-
-
Bartlett, N.W.1
-
26
-
-
0023746463
-
Primary respiratory syncytial virus infection in mice
-
Graham, B. S., Perkins, M. D., Wright, P. F & Karzon, D. T. Primary respiratory syncytial virus infection in mice. J. Med. Virol. 26, 153-162 (1988).
-
(1988)
J. Med. Virol.
, vol.26
, pp. 153-162
-
-
Graham, B.S.1
Perkins, M.D.2
Wright, P.F.3
Karzon, D.T.4
-
27
-
-
66049132845
-
Immune pathways for translating viral infection into chronic airway disease
-
Holtzman, M. J. et al. Immune pathways for translating viral infection into chronic airway disease. Adv. Immunol. 102, 245-276 (2009)
-
(2009)
Adv. Immunol.
, vol.102
, pp. 245-276
-
-
Holtzman, M.J.1
-
28
-
-
77952784713
-
Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease
-
Motz, G. T. et al. Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease. J. Immunol. 184, 4460-4469 (2010)
-
(2010)
J. Immunol.
, vol.184
, pp. 4460-4469
-
-
Motz, G.T.1
-
29
-
-
31044448784
-
Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema
-
Ma, B. et al. Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema. J. Clin. Invest. 115, 3460-3472 (2005)
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3460-3472
-
-
Ma, B.1
-
30
-
-
13644267621
-
Characterization of cigarette smoke-induced infl ammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect
-
Stevenson, CS et al. Characterization of cigarette smoke-induced infl ammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect. Am. J. Physiol. Lung Cell. Mol. Physiol. 288, L514-L522 (2005).
-
(2005)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.288
-
-
Stevenson, C.S.1
-
31
-
-
79551591691
-
Pharmacological characterisation of anti-infl ammatory compounds in acute and chronic mouse models of cigarette smoke-induced infl ammation
-
Wan, W. Y et al. Pharmacological characterisation of anti-infl ammatory compounds in acute and chronic mouse models of cigarette smoke-induced infl ammation. Respir. Res. 11, 126 (2010).
-
(2010)
Respir. Res.
, vol.11
, pp. 126
-
-
Wan, W.Y.1
-
32
-
-
0032798485
-
CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease
-
Saetta, M. et al. CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 160, 711-717 (1999)
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.160
, pp. 711-717
-
-
Saetta, M.1
-
33
-
-
56149112179
-
Respiratory syncytial virus persistence in chronic obstructive pulmonary disease
-
Sikkel, M. B., Quint, J. K., Mallia, P., Wedzicha, J. A. & Johnston, S. L. Respiratory syncytial virus persistence in chronic obstructive pulmonary disease. Pediatr. Infect. Dis. J. 27 (10 Suppl), S63-S70 (2008)
-
(2008)
Pediatr. Infect. Dis. J.
, vol.27
, Issue.10 SUPPL.
-
-
Sikkel, M.B.1
Quint, J.K.2
Mallia, P.3
Wedzicha, J.A.4
Johnston, S.L.5
-
34
-
-
18744389489
-
Signifi cance analysis of functional categories in gene expression studies: A structured permutation approach
-
Barry, W. T., Nobel, A. B. & Wright, F A. Signifi cance analysis of functional categories in gene expression studies: a structured permutation approach. Bioinformatics 21, 1943-1949 (2005)
-
(2005)
Bioinformatics
, vol.21
, pp. 1943-1949
-
-
Barry, W.T.1
Nobel, A.B.2
Wright, F.A.3
-
35
-
-
3142673366
-
Using the gene ontology for microarray data mining: A comparison of methods and application to age effects in human prefrontal cortex
-
Pavlidis, P., Qin, J., Arango, V, Mann, J. J. & Sibille, E. Using the gene ontology for microarray data mining: a comparison of methods and application to age effects in human prefrontal cortex. Neurochem. Res. 29, 1213-1222 (2004).
-
(2004)
Neurochem. Res.
, vol.29
, pp. 1213-1222
-
-
Pavlidis, P.1
Qin, J.2
Arango, V.3
Mann, J.J.4
Sibille, E.5
-
36
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profi les
-
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profi les. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005)
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
37
-
-
31144459985
-
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
-
Bild, A. H. et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 439, 353-357 (2006)
-
(2006)
Nature
, vol.439
, pp. 353-357
-
-
Bild, A.H.1
-
38
-
-
77952987104
-
Airway PI3K pathway activation is an early and reversible event in lung cancer development
-
Gustafson, A. M. et al. Airway PI3K pathway activation is an early and reversible event in lung cancer development. Sci. Translational Med. 2, 26ra25 (2010).
-
(2010)
Sci. Translational Med.
, vol.2
-
-
Gustafson, A.M.1
-
39
-
-
34250945149
-
Versuchsanordnung zu Untersuchungen an der Bronchialmuskulatur
-
Konzett, H. R. Versuchsanordnung zu Untersuchungen an der Bronchialmuskulatur. Naunyn-Schmiedeberg's Arch. Pharmacol 195, 71-74 (1940).
-
(1940)
Naunyn-Schmiedeberg's Arch. Pharmacol
, vol.195
, pp. 71-74
-
-
Konzett, H.R.1
-
40
-
-
0001677717
-
Controlling the false discovery rate-a practical and powerful approach to multiple testing
-
Benjamini, Y & Hochberg, Y Controlling the false discovery rate-a practical and powerful approach to multiple testing. J. R. Stat. Soc. B Met. 57, 289-300 (1995).
-
(1995)
J. R. Stat. Soc. B Met.
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
|