Mechanisms involved in postconditioning protection of cardiomyocytes against acute reperfusion injury

Journal of Molecular and Cellular Cardiology

Volumn 58, Issue 1, 2013, Pages 209-216

  Shahzad, Tayyab ^a   Kasseckert, Sascha Andreas ^b   Iraqi, Wisam ^b   Johnson, Victoria ^a   Schulz, Rainer ^b   Schlüter, Klaus Dieter ^b   Dörr, Oliver ^a   Parahuleva, Mariana ^a   Hamm, Christian ^a   Ladilov, Yury ^c   Abdallah, Yaser ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Acidosis; Cardiomyocytes; Mitochondrial permeability transition pore; Postconditioning; Reperfusion injury

Indexed keywords

CALCEIN; CALCIUM ION; CYCLOSPORIN A; GLUCOSE; PROPIDIUM IODIDE;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFICACY; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPOXIA; IN VITRO STUDY; ISCHEMIC POSTCONDITIONING; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; NECROSIS; NONHUMAN; OSCILLATION; PH; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION INJURY; TREATMENT RESPONSE;

ANIMALS; ANOXIA; CALCIUM; CYTOSOL; FURA-2; HUMANS; ISCHEMIC POSTCONDITIONING; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; RATS;

RATTUS;

EID: 84876324368     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.01.003     Document Type: Article

References (37)

1. Staat P., Rioufol G., Piot C., Cottin Y., Cung T.T., L'Huillier I., et al. Postconditioning the human heart. Circulation 2005, 112:2143-2148.
2. Thibault H., Piot C., Ovize M. Postconditioning in man. Heart Fail Rev 2007, 2:245-248.
3. Ovize M., Baxter G.F., Di Lisa F., Ferdinandy P., Garcia-Dorado D., Hausenloy D.J., et al. Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res 2010, 87:406-423.
4. Zhao Z.Q., Corvera J.S., Halkos M.E., Kerendi F., Wang N.P., Guyton R., et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 2003, 285:H579-H588.
5. 2+ overload. Am J Physiol Heart Circ Physiol 2005, 288:H1900-H1908.
6. Skyschally A., van Caster P., Iliodromitis E.K., Schulz R., Kremastinos D.T., Heusch G. Ischemic postconditioning: experimental models and protocol algorithms. Basic Res Cardiol 2009, 104:469-483.
7. Gateau-Roesch O., Argaud L., Ovize M. Mitochondrial permeability transition pore and postconditioning. Cardiovasc Res 2006, 70:264-273.
8. Argaud L., Gateau-Roesch O., Raisky O., Loufouat J., Robert D., Ovize M. Postconditioning inhibits mitochondrial permeability transition. Circulation 2005, 111:194-197.
9. Xie J.R., Yu L.N. Cardioprotective effects of cyclosporine A in an in vivo model of myocardial ischemia and reperfusion. Acta Anaesthesiol Scand 2007, 51:909-913.
10. Piot C., Croisille P., Staat P., Thibault H., Rioufol G., Mewton N., et al. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med 2008, 359:473-481.
11. Halestrap A.P., Clarke S.J., Javadov S.A. Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection. Cardiovasc Res 2004, 61:372-385.
12. Honda H.M., Ping P. Mitochondrial permeability transition in cardiac cell injury and death. Cardiovasc Drugs Ther 2006, 20:425-432.
13. Cohen M.V., Yang X.M., Downey J.M. The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis. Circulation 2007, 115:1895-1903.
14. Inserte J., Barba I., Poncelas-Nozal M., Hernando V., Agulló L., Ruiz-Meana M., et al. cGMP/PKG pathway mediates myocardial postconditioning protection in rat hearts by delaying normalization of intracellular acidosis during reperfusion. J Mol Cell Cardiol 2011, 50:903-909.
15. Musiolik J., van Caster P., Skyschally A., Boengler K., Gres P., Schulz R., et al. Reduction of infarct size by gentle reperfusion without activation of reperfusion injury salvage kinases in pigs. Cardiovasc Res 2010, 85:110-117.
16. Abdallah Y., Kasseckert S.A., Iraqi W., Said M., Shahzad T., Erdogan A., et al. Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes. J Cell Mol Med 2011, 15:2478-2485.
17. Siegmund B., Schlack W., Ladilov Y.V., Balser C., Piper H.M. Halothane protects cardiomyocytes against reoxygenation-induced hypercontracture. Circulation 1997, 96:4372-4379.
18. Duchen M.R., Leyssens A., Crompton M. Transient mitochondrial depolarizations reflect focal sarcoplasmic reticular calcium release in single rat cardiomyocytes. J Cell Biol 1998, 142:975-988.
19. Szalai G., Csordás G., Hantash B.M., Thomas A.P., Hajnóczky G. Calcium signal transmission between ryanodine receptors and mitochondria. J Biol Chem 2000, 275:15305-15313.
20. Schlüter K.D., Schreiber D. Adult ventricular cardiomyocytes: isolation and culture. Methods Mol Biol 2005, 290:305-314.
21. Ladilov Y.V., Siegmund B., Piper H.M. Protection of reoxygenated cardiomyocytes against hypercontracture by inhibition of Na+/H+exchange. Am J Physiol Heart Circ Physiol 1995, 268:H1531-H1539.
22. Ladilov Y.V., Balser C., Piper H.M. Protection of rat cardiomyocytes against simulated ischemia and reoxygenation by treatment with protein kinase C activator. Circ Res 1998, 82:451-457.
23. 3 receptor. EMBO J 1997, 16:3533-3543.
24. Di Lisa F., Blank P.S., Colonna R., Gambassi G., Silverman H.S., Stern M.D., et al. Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition. J Physiol 1995, 486:1-13.
25. Franck P., Petitipain N., Cherlet M., Dardennes M., Maachi F., Schutz B., et al. Measurement of intracellular pH in cultured cells by flow cytometry with BCECF-AM. J Biotechnol 1996, 46:187-195.
26. Garcia-Dorado D., Theroux P., Duran J.M., Solares J., Alonso J., Sanz E., et al. Selective inhibition of the contractile apparatus. A new approach to modification of infarct size, infarct composition, and infarct geometry during coronary artery occlusion and reperfusion. Circulation 1992, 85:1160-1174.
27. Halkos M.E., Kerendi F., Corvera J.S., Wang N.P., Kin H., Payne C.S., et al. Myocardial protection with postconditioning is not enhanced by ischemic preconditioning. Ann Thorac Surg 2004, 78:961-969.
28. Nakagawa T., Shimizu S., Watanabe T., Yamaguchi O., Otsu K., Yamagata H., et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005, 434:652-658.
29. Baines C.P., Kaiser R.A., Purcell N.H., Blair N.S., Osinska H., Hambleton M.A. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 2005, 434:658-662.
30. Lim S.Y., Davidson S.M., Hausenloy D.J., Yellon D.M. Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore. Cardiovasc Res 2007, 75:530-535.
31. Gomez L., Li B., Mewton N., Sanchez I., Piot C., Elbaz M., et al. Inhibition of mitochondrial permeability transition pore opening: translation to patients. Cardiovasc Res 2009, 15:226-233.
32. Gomez L., Thibault H., Gharib A., Dumont J.M., Vuagniaux G., Scalfaro P., et al. Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice. Am J Physiol Heart Circ Physiol 2007, 293:H1654-H1661.
33. Sheu J.J., Chua S., Sun C.K., Chang L.T., Yen C.H., Wu C.J., et al. Intra-coronary administration of cyclosporine limits infarct size, attenuates remodeling and preserves left ventricular function in porcine acute anterior infarction. Int J Cardiol 2011, 147:79-87.
34. De Windt L.J., Lim H.W., Taigen T., Wencker D., Condorelli G., et al. Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: an apoptosis-independent model of dilated heart failure. Circ Res 2000, 86:255-263.
35. Obasanjo-Blackshire K., Mesquita R., Jabr R.I., Molkentin J.D., Hart S.L., Marber M.S., et al. Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: co-operation with Src tyrosine kinase. Cardiovasc Res 2006, 71:672-683.
36. Fujita M., Asanuma H., Hirata A., Wakeno M., Takahama H., Sasaki H., et al. Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning. Am J Physiol Heart Circ Physiol 2007, 292:H2004-H2008.
37. Nicolli A., Petronilli V., Bernardi P. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation. Biochemistry 1993, 32:4461-4465.