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Volumn 33, Issue 8, 2013, Pages 1657-1670

Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN GRB2 ASSOCIATED BINDER; PROTEIN P90; PROTEIN S6; PROTEIN TYROSINE PHOSPHATASE SHP 2; UNCLASSIFIED DRUG;

EID: 84876320925     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01353-12     Document Type: Article
Times cited : (33)

References (43)
  • 1
    • 77953896432 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Lemmon MA, Schlessinger J. 2010. Cell signaling by receptor tyrosine kinases. Cell 141:1117-1134.
    • (2010) Cell , vol.141 , pp. 1117-1134
    • Lemmon, M.A.1    Schlessinger, J.2
  • 2
    • 33646336602 scopus 로고    scopus 로고
    • MAPK signal specificity: the right place at the right time
    • Murphy LO, Blenis J. 2006. MAPK signal specificity: the right place at the right time. Trends Biochem. Sci. 31:268-275.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 268-275
    • Murphy, L.O.1    Blenis, J.2
  • 3
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
    • Roux PP, Blenis J. 2004. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68:320-344.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 4
    • 79952435349 scopus 로고    scopus 로고
    • Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
    • Cargnello M, Roux PP. 2011. Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol. Mol. Biol. Rev. 75:50-83.
    • (2011) Microbiol. Mol. Biol. Rev. , vol.75 , pp. 50-83
    • Cargnello, M.1    Roux, P.P.2
  • 5
    • 84555189440 scopus 로고    scopus 로고
    • Regulation and function of the RSK family of protein kinases
    • Romeo Y, Zhang X, Roux PP. 2012. Regulation and function of the RSK family of protein kinases. Biochem. J. 441:553-569.
    • (2012) Biochem. J. , vol.441 , pp. 553-569
    • Romeo, Y.1    Zhang, X.2    Roux, P.P.3
  • 6
    • 42949169517 scopus 로고    scopus 로고
    • The RSK factors of activating the Ras/MAPK signaling cascade
    • Carriere A, Ray H, Blenis J, Roux PP. 2008. The RSK factors of activating the Ras/MAPK signaling cascade. Front. Biosci. 13:4258-4275.
    • (2008) Front. Biosci. , vol.13 , pp. 4258-4275
    • Carriere, A.1    Ray, H.2    Blenis, J.3    Roux, P.P.4
  • 8
    • 0037333264 scopus 로고    scopus 로고
    • The "Gab" in signal transduction
    • Gu H, Neel BG. 2003. The "Gab" in signal transduction. Trends Cell Biol. 13:122-130.
    • (2003) Trends Cell Biol. , vol.13 , pp. 122-130
    • Gu, H.1    Neel, B.G.2
  • 9
    • 77955599451 scopus 로고    scopus 로고
    • Function, regulation and pathological roles of the Gab/DOS docking proteins
    • doi:10.1186/1478-811X-7-22.
    • Wohrle FU, Daly RJ, Brummer T. 2009. Function, regulation and pathological roles of the Gab/DOS docking proteins. Cell Commun. Signal 7:22. doi:10.1186/1478-811X-7-22.
    • (2009) Cell Commun. Signal , vol.7 , pp. 22
    • Wohrle, F.U.1    Daly, R.J.2    Brummer, T.3
  • 10
    • 66349113403 scopus 로고    scopus 로고
    • How to Grb2 a Gab. Structure
    • Wohrle FU, Daly RJ, Brummer T. 2009. How to Grb2 a Gab. Structure 17:779-781.
    • (2009) , vol.17 , pp. 779-781
    • Wohrle, F.U.1    Daly, R.J.2    Brummer, T.3
  • 11
    • 0347660479 scopus 로고    scopus 로고
    • The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors
    • Nishida K, Hirano T. 2003. The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors. Cancer Sci. 94:1029-1033.
    • (2003) Cancer Sci. , vol.94 , pp. 1029-1033
    • Nishida, K.1    Hirano, T.2
  • 13
    • 33644850529 scopus 로고    scopus 로고
    • Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein
    • Brummer T, Schramek D, Hayes VM, Bennett HL, Caldon CE, Musgrove EA, Daly RJ. 2006. Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein. J. Biol. Chem. 281:626-637.
    • (2006) J. Biol. Chem. , vol.281 , pp. 626-637
    • Brummer, T.1    Schramek, D.2    Hayes, V.M.3    Bennett, H.L.4    Caldon, C.E.5    Musgrove, E.A.6    Daly, R.J.7
  • 17
    • 0037080536 scopus 로고    scopus 로고
    • PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2
    • Lynch DK, Daly RJ. 2002. PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2. EMBO J. 21:72-82.
    • (2002) EMBO J. , vol.21 , pp. 72-82
    • Lynch, D.K.1    Daly, R.J.2
  • 18
    • 4644275694 scopus 로고    scopus 로고
    • Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation
    • Arnaud M, Crouin C, Deon C, Loyaux D, Bertoglio J. 2004. Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation. J. Immunol. 173:3962-3971.
    • (2004) J. Immunol. , vol.173 , pp. 3962-3971
    • Arnaud, M.1    Crouin, C.2    Deon, C.3    Loyaux, D.4    Bertoglio, J.5
  • 20
    • 62749184858 scopus 로고    scopus 로고
    • Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells
    • Caron C, Spring K, Laramee M, Chabot C, Cloutier M, Gu H, Royal I. 2009. Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells. Cell Signal. 21:943-953.
    • (2009) Cell Signal. , vol.21 , pp. 943-953
    • Caron, C.1    Spring, K.2    Laramee, M.3    Chabot, C.4    Cloutier, M.5    Gu, H.6    Royal, I.7
  • 21
    • 0035985205 scopus 로고    scopus 로고
    • Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis
    • Lock LS, Maroun CR, Naujokas MA, Park M. 2002. Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis. Mol. Biol. Cell 13:2132-2146.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2132-2146
    • Lock, L.S.1    Maroun, C.R.2    Naujokas, M.A.3    Park, M.4
  • 24
    • 51049083138 scopus 로고    scopus 로고
    • Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
    • Carriere A, Cargnello M, Julien LA, Gao H, Bonneil E, Thibault P, Roux PP. 2008. Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation. Curr. Biol. 18:1269-1277.
    • (2008) Curr. Biol. , vol.18 , pp. 1269-1277
    • Carriere, A.1    Cargnello, M.2    Julien, L.A.3    Gao, H.4    Bonneil, E.5    Thibault, P.6    Roux, P.P.7
  • 26
    • 4544384577 scopus 로고    scopus 로고
    • Tumorpromoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
    • Roux PP, Ballif BA, Anjum R, Gygi SP, Blenis J. 2004. Tumorpromoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. Proc. Natl. Acad. Sci. U. S. A. 101:13489-13494.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 13489-13494
    • Roux, P.P.1    Ballif, B.A.2    Anjum, R.3    Gygi, S.P.4    Blenis, J.5
  • 27
    • 0029927505 scopus 로고    scopus 로고
    • Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
    • Shevchenko A, Wilm M, Vorm O, Mann M. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68:850-858.
    • (1996) Anal. Chem. , vol.68 , pp. 850-858
    • Shevchenko, A.1    Wilm, M.2    Vorm, O.3    Mann, M.4
  • 29
    • 80155124832 scopus 로고    scopus 로고
    • MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
    • Ting L, Rad R, Gygi SP, Haas W. 2011. MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics. Nat. Methods 8:937-940.
    • (2011) Nat. Methods , vol.8 , pp. 937-940
    • Ting, L.1    Rad, R.2    Gygi, S.P.3    Haas, W.4
  • 30
    • 0037317228 scopus 로고    scopus 로고
    • Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
    • Rappsilber J, Ishihama Y, Mann M. 2003. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 75:663-670.
    • (2003) Anal. Chem. , vol.75 , pp. 663-670
    • Rappsilber, J.1    Ishihama, Y.2    Mann, M.3
  • 31
    • 0029644596 scopus 로고
    • Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database
    • Yates JR, III, Eng JK, McCormack AL, Schieltz D. 1995. Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database. Anal. Chem. 67:1426-1436.
    • (1995) Anal. Chem. , vol.67 , pp. 1426-1436
    • Yates III, J.R.1    Eng, J.K.2    McCormack, A.L.3    Schieltz, D.4
  • 32
    • 33847630405 scopus 로고    scopus 로고
    • Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
    • Elias JE, Gygi SP. 2007. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat. Methods 4:207-214.
    • (2007) Nat. Methods , vol.4 , pp. 207-214
    • Elias, J.E.1    Gygi, S.P.2
  • 34
    • 33749853607 scopus 로고    scopus 로고
    • A probabilitybased approach for high-throughput protein phosphorylation analysis and site localization
    • Beausoleil SA, Villen J, Gerber SA, Rush J, Gygi SP. 2006. A probabilitybased approach for high-throughput protein phosphorylation analysis and site localization. Nat. Biotechnol. 24:1285-1292.
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1285-1292
    • Beausoleil, S.A.1    Villen, J.2    Gerber, S.A.3    Rush, J.4    Gygi, S.P.5
  • 35
    • 0025066941 scopus 로고
    • More powerful procedures for multiple significance testing
    • Hochberg Y, Benjamini Y. 1990. More powerful procedures for multiple significance testing. Stat. Med. 9:811-818.
    • (1990) Stat. Med. , vol.9 , pp. 811-818
    • Hochberg, Y.1    Benjamini, Y.2
  • 36
    • 75749105049 scopus 로고    scopus 로고
    • mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling
    • Julien LA, Carriere A, Moreau J, Roux PP. 2010. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. Mol. Cell. Biol. 30:908-921.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 908-921
    • Julien, L.A.1    Carriere, A.2    Moreau, J.3    Roux, P.P.4
  • 37
    • 0030590875 scopus 로고    scopus 로고
    • Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
    • Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. 1996. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399:333-338.
    • (1996) FEBS Lett. , vol.399 , pp. 333-338
    • Alessi, D.R.1    Caudwell, F.B.2    Andjelkovic, M.3    Hemmings, B.A.4    Cohen, P.5
  • 38
    • 62449265137 scopus 로고    scopus 로고
    • Inhibition of the antigen-induced activation of RBL-2H3 cells by Gab2 siRNA
    • Huang F, Tong X, Deng H, Fu L, Zhang R. 2008. Inhibition of the antigen-induced activation of RBL-2H3 cells by Gab2 siRNA. Cell. Mol. Immunol. 5:433-438.
    • (2008) Cell. Mol. Immunol. , vol.5 , pp. 433-438
    • Huang, F.1    Tong, X.2    Deng, H.3    Fu, L.4    Zhang, R.5
  • 40
    • 0038771965 scopus 로고    scopus 로고
    • The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
    • Neel BG, Gu H, Pao L. 2003. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 28:284-293.
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 284-293
    • Neel, B.G.1    Gu, H.2    Pao, L.3
  • 41
    • 45349107819 scopus 로고    scopus 로고
    • Regulation of RhoA-dependent ROCKII activation by Shp2
    • Lee HH, Chang ZF. 2008. Regulation of RhoA-dependent ROCKII activation by Shp2. J. Cell Biol. 181:999-1012.
    • (2008) J. Cell Biol. , vol.181 , pp. 999-1012
    • Lee, H.H.1    Chang, Z.F.2
  • 43
    • 78650209096 scopus 로고    scopus 로고
    • Paving the way for targeting RSK in cancer
    • Romeo Y, Roux PP. 2011. Paving the way for targeting RSK in cancer. Expert Opin. Ther. Targets 15:5-9.
    • (2011) Expert Opin. Ther. Targets , vol.15 , pp. 5-9
    • Romeo, Y.1    Roux, P.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.