메뉴 건너뛰기




Volumn 72, Issue SUPPL. 2, 2013, Pages

Recent insights into the genetic basis of systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALPHA INTERFERON; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BETA INTERFERON; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DEOXYRIBONUCLEASE I; FC RECEPTOR; HERMES ANTIGEN; HLA DR2 ANTIGEN; HLA DR3 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 2; INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 5; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 21; MICRORNA 146A; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; OX40 LIGAND; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN KINASE C BETA; PROTEIN KINASE TYK2; STAT4 PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TRANSCRIPTION FACTOR ETS 1;

EID: 84876282977     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2012-202351     Document Type: Article
Times cited : (120)

References (80)
  • 1
    • 82555196095 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Tsokos GC. Systemic lupus erythematosus. N Engl J Med 2011;365:2110-21.
    • (2011) N Engl J Med , vol.365 , pp. 2110-2121
    • Tsokos, G.C.1
  • 4
    • 33744822178 scopus 로고    scopus 로고
    • Epidemiology of systemic lupus erythematosus: A comparison of worldwide disease burden
    • DOI 10.1191/0961203306lu2305xx
    • Danchenko N, Satia JA, Anthony MS. Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden. Lupus 2006;15:308-18. (Pubitemid 43828810)
    • (2006) Lupus , vol.15 , Issue.5 , pp. 308-318
    • Danchenko, N.1    Satia, J.A.2    Anthony, M.S.3
  • 5
    • 43249119095 scopus 로고    scopus 로고
    • Defining the role of the MHC in autoimmunity: A review and pooled analysis
    • Fernando MM, Stevens CR, Walsh EC, et al. Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet 2008;4:e1000024.
    • (2008) PLoS Genet , vol.4
    • Fernando, M.M.1    Stevens, C.R.2    Walsh, E.C.3
  • 6
    • 84862777422 scopus 로고    scopus 로고
    • Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G
    • Fernando MM, Freudenberg J, Lee A, et al. Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G. Ann Rheum Dis 2012;71:777-84.
    • (2012) Ann Rheum Dis , vol.71 , pp. 777-784
    • Fernando, M.M.1    Freudenberg, J.2    Lee, A.3
  • 8
    • 79958015275 scopus 로고    scopus 로고
    • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
    • Namjou B, Kothari PH, Kelly JA, et al. Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun 2011;12:270-9.
    • (2011) Genes Immun , vol.12 , pp. 270-279
    • Namjou, B.1    Kothari, P.H.2    Kelly, J.A.3
  • 9
    • 79251551861 scopus 로고    scopus 로고
    • Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature
    • Briggs TA, Rice GI, Daly S, et al. Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature. Nat Genet 2011;43:127-31.
    • (2011) Nat Genet , vol.43 , pp. 127-131
    • Briggs, T.A.1    Rice, G.I.2    Daly, S.3
  • 10
    • 77956261467 scopus 로고    scopus 로고
    • TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population
    • He CF, Liu YS, Cheng YL, et al. TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population. Lupus 2010;19:1181-6.
    • (2010) Lupus , vol.19 , pp. 1181-1186
    • He, C.F.1    Liu, Y.S.2    Cheng, Y.L.3
  • 11
    • 77951737544 scopus 로고    scopus 로고
    • Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutieres syndrome
    • Ramantani G, Kohlhase J, Hertzberg C, et al. Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutieres syndrome. Arthritis Rheum 2010;62:1469-77.
    • (2010) Arthritis Rheum , vol.62 , pp. 1469-1477
    • Ramantani, G.1    Kohlhase, J.2    Hertzberg, C.3
  • 12
    • 75749110600 scopus 로고    scopus 로고
    • Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients
    • Salloum R, Franek BS, Kariuki SN, et al. Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients. Arthritis Rheum 2010;62:553-61.
    • (2010) Arthritis Rheum , vol.62 , pp. 553-561
    • Salloum, R.1    Franek, B.S.2    Kariuki, S.N.3
  • 13
    • 84861806223 scopus 로고    scopus 로고
    • Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population
    • Kawasaki A, Furukawa H, Kondo Y, et al. Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population. Lupus 2012;21:890-5.
    • (2012) Lupus , vol.21 , pp. 890-895
    • Kawasaki, A.1    Furukawa, H.2    Kondo, Y.3
  • 14
    • 80051619284 scopus 로고    scopus 로고
    • Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-alpha and serologic autoimmunity in lupus patients
    • Robinson T, Kariuki SN, Franek BS, et al. Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-alpha and serologic autoimmunity in lupus patients. J Immunol 2011;187:1298-303.
    • (2011) J Immunol , vol.187 , pp. 1298-1303
    • Robinson, T.1    Kariuki, S.N.2    Franek, B.S.3
  • 15
    • 79953743757 scopus 로고    scopus 로고
    • Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production
    • Chung SA, Taylor KE, Graham RR, et al. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet 2011;7:e1001323.
    • (2011) PLoS Genet , vol.7
    • Chung, S.A.1    Taylor, K.E.2    Graham, R.R.3
  • 16
    • 84863115400 scopus 로고    scopus 로고
    • IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus
    • Niewold TB, Kelly JA, Kariuki SN, et al. IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus. Ann Rheum Dis 2012;71:463-8.
    • (2012) Ann Rheum Dis , vol.71 , pp. 463-468
    • Niewold, T.B.1    Kelly, J.A.2    Kariuki, S.N.3
  • 17
    • 77957673544 scopus 로고    scopus 로고
    • Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus
    • Shen N, Fu Q, Deng Y, et al. Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Proc Natl Acad Sci U S A 2010;107:15838-43.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15838-15843
    • Shen, N.1    Fu, Q.2    Deng, Y.3
  • 18
    • 8344242991 scopus 로고    scopus 로고
    • Interleukin-10 promoter microsatellite polymorphisms in systemic lupus erythematosus: Association with the anti-Sm immune response
    • DOI 10.1093/rheumatology/keh353
    • Schotte H, Gaubitz M, Willeke P, et al. Interleukin-10 promoter microsatellite polymorphisms in systemic lupus erythematosus: association with the anti-Sm immune response. Rheumatology (Oxford) 2004;43:1357-63. (Pubitemid 39480922)
    • (2004) Rheumatology , vol.43 , Issue.11 , pp. 1357-1363
    • Schotte, H.1    Gaubitz, M.2    Willeke, P.3    Tidow, N.4    Assmann, G.5    Domschke, W.6    Schluter, B.7
  • 19
    • 82255192363 scopus 로고    scopus 로고
    • Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus
    • Al-Mayouf SM, Sunker A, Abdwani RA, et al. Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus. Nat Genet 2011;43:1186-8.
    • (2011) Nat Genet , vol.43 , pp. 1186-1188
    • Al-Mayouf, S.M.1    Sunker, A.2    Abdwani, R.A.3
  • 20
    • 8144224559 scopus 로고    scopus 로고
    • Interleukin (IL)-10, IL-1ra and IL-12 profiles in active and quiescent systemic lupus erythematosus: Could longitudinal studies reveal patient subgroups of differing pathology?
    • DOI 10.1111/j.1365-2249.2004.02607.x
    • Capper ER, Maskill JK, Gordon C, et al. Interleukin (IL)-10, IL-1ra and IL-12 profiles in active and quiescent systemic lupus erythematosus: could longitudinal studies reveal patient subgroups of differing pathology? Clin Exp Immunol 2004;138:348-56. (Pubitemid 39472455)
    • (2004) Clinical and Experimental Immunology , vol.138 , Issue.2 , pp. 348-356
    • Capper, E.R.1    Maskill, J.K.2    Gordon, C.3    Blakemore, A.I.F.4
  • 21
    • 68049107373 scopus 로고    scopus 로고
    • Association of STAT4 and BLK, but not BANK1 or IRF5, with primary antiphospholipid syndrome
    • Yin H, Borghi MO, Delgado-Vega AM, et al. Association of STAT4 and BLK, but not BANK1 or IRF5, with primary antiphospholipid syndrome. Arthritis Rheum 2009;60:2468-71.
    • (2009) Arthritis Rheum , vol.60 , pp. 2468-2471
    • Yin, H.1    Borghi, M.O.2    Delgado-Vega, A.M.3
  • 22
    • 80052461085 scopus 로고    scopus 로고
    • Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus
    • Sanchez E, Nadig A, Richardson BC, et al. Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Ann Rheum Dis 2011;70:1752-7.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1752-1757
    • Sanchez, E.1    Nadig, A.2    Richardson, B.C.3
  • 23
    • 80054736581 scopus 로고    scopus 로고
    • Functional complement C1q abnormality leads to impaired immune complexes and apoptotic cell clearance
    • Roumenina LT, Sene D, Radanova M, et al. Functional complement C1q abnormality leads to impaired immune complexes and apoptotic cell clearance. J Immunol 2011;187:4369-73.
    • (2011) J Immunol , vol.187 , pp. 4369-4373
    • Roumenina, L.T.1    Sene, D.2    Radanova, M.3
  • 24
    • 37349066319 scopus 로고    scopus 로고
    • Complement deficiencies and systemic lupus erythematosus
    • DOI 10.1080/08916930701510673, PII 788414850
    • Truedsson L, Bengtsson AA, Sturfelt G. Complement deficiencies and systemic lupus erythematosus. Autoimmunity 2007;40:560-6. (Pubitemid 350302182)
    • (2007) Autoimmunity , vol.40 , Issue.8 , pp. 560-566
    • Truedsson, L.1    Bengtsson, A.A.2    Sturfelt, G.3
  • 25
    • 44949149145 scopus 로고    scopus 로고
    • Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus
    • Taylor KE, Remmers EF, Lee AT, et al. Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus. PLoS Genet 2008;4:e1000084.
    • (2008) PLoS Genet , vol.4
    • Taylor, K.E.1    Remmers, E.F.2    Lee, A.T.3
  • 26
    • 67849116005 scopus 로고    scopus 로고
    • Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations
    • Bates JS, Lessard CJ, Leon JM, et al. Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations. Genes Immun 2009;10:470-7.
    • (2009) Genes Immun , vol.10 , pp. 470-477
    • Bates, J.S.1    Lessard, C.J.2    Leon, J.M.3
  • 27
    • 33750887728 scopus 로고    scopus 로고
    • Time to renal disease and end-stage renal disease in PROFILE: A multiethnic lupus cohort
    • Alarcon GS, McGwin G Jr, Petri M, et al. Time to renal disease and end-stage renal disease in PROFILE: a multiethnic lupus cohort. PLoS Med 2006;3:e396.
    • (2006) PLoS Med , vol.3
    • Alarcon, G.S.1    McGwin Jr., G.2    Petri, M.3
  • 28
    • 29944444594 scopus 로고    scopus 로고
    • Association of interleukin-10 gene-592 A/C polymorphism with the clinical and pathological diversity of lupus nephritis
    • Zhu LJ, Liu ZH, Zeng CH, et al. Association of interleukin-10 gene-592 A/C polymorphism with the clinical and pathological diversity of lupus nephritis. Clin Exp Rheumatol 2005;23:854-60.
    • (2005) Clin Exp Rheumatol , vol.23 , pp. 854-860
    • Zhu, L.J.1    Liu, Z.H.2    Zeng, C.H.3
  • 29
    • 67849097322 scopus 로고    scopus 로고
    • Genetic associations of LYN with systemic lupus erythematosus
    • Lu R, Vidal GS, Kelly JA, et al. Genetic associations of LYN with systemic lupus erythematosus. Genes Immun 2009;10:397-403.
    • (2009) Genes Immun , vol.10 , pp. 397-403
    • Lu, R.1    Vidal, G.S.2    Kelly, J.A.3
  • 30
    • 34547396536 scopus 로고    scopus 로고
    • A genetic marker within the CD44 gene confirms linkage at 11p13 in African-American families with lupus stratified by thrombocytopenia, but genetic association with CD44 is not present
    • Kaufman KM, Rankin J, Harley IT, et al. A genetic marker within the CD44 gene confirms linkage at 11p13 in African-American families with lupus stratified by thrombocytopenia, but genetic association with CD44 is not present. Genes Immun 2002;3:S86-8.
    • (2002) Genes Immun , vol.3
    • Kaufman, K.M.1    Rankin, J.2    Harley, I.T.3
  • 33
    • 79957991917 scopus 로고    scopus 로고
    • Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
    • Zhao J, Wu H, Khosravi M, et al. Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet 2011;7:e1002079.
    • (2011) PLoS Genet , vol.7
    • Zhao, J.1    Wu, H.2    Khosravi, M.3
  • 34
    • 78649879413 scopus 로고    scopus 로고
    • Genetic variation, Fcgamma receptors, KIRs and infection: The evolution of autoimmunity
    • Espeli M, Niederer HA, Traherne JA, et al. Genetic variation, Fcgamma receptors, KIRs and infection: the evolution of autoimmunity. Curr Opin Immunol 2010;22:715-22.
    • (2010) Curr Opin Immunol , vol.22 , pp. 715-722
    • Espeli, M.1    Niederer, H.A.2    Traherne, J.A.3
  • 35
    • 67849092283 scopus 로고    scopus 로고
    • Fcgamma receptors: Structure, function and role as genetic risk factors in SLE
    • Li X, Ptacek TS, Brown EE, et al. Fcgamma receptors: structure, function and role as genetic risk factors in SLE. Genes Immun 2009;10:380-9.
    • (2009) Genes Immun , vol.10 , pp. 380-389
    • Li, X.1    Ptacek, T.S.2    Brown, E.E.3
  • 36
    • 77649338622 scopus 로고    scopus 로고
    • Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases
    • Mamtani M, Anaya JM, He W, et al. Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases. Genes Immun 2010;11:155-60.
    • (2010) Genes Immun , vol.11 , pp. 155-160
    • Mamtani, M.1    Anaya, J.M.2    He, W.3
  • 37
    • 0034613151 scopus 로고    scopus 로고
    • Immune inhibitory receptors
    • Ravetch JV, Lanier LL. Immune inhibitory receptors. Science 2000;290:84-9.
    • (2000) Science , vol.290 , pp. 84-89
    • Ravetch, J.V.1    Lanier, L.L.2
  • 38
    • 77951572775 scopus 로고    scopus 로고
    • A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus
    • Willcocks LC, Carr EJ, Niederer HA, et al. A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus. Proc Natl Acad Sci U S A 2010;1077881-5.
    • (2010) Proc Natl Acad Sci U S A , pp. 1077881-5
    • Willcocks, L.C.1    Carr, E.J.2    Niederer, H.A.3
  • 39
    • 80955139536 scopus 로고    scopus 로고
    • Type I interferon and systemic lupus erythematosus
    • Elkon KB, Stone VV. Type I interferon and systemic lupus erythematosus. J Interferon Cytokine Res 2011;31:803-12.
    • (2011) J Interferon Cytokine Res , vol.31 , pp. 803-812
    • Elkon, K.B.1    Stone, V.V.2
  • 40
    • 84876280656 scopus 로고    scopus 로고
    • Association of a functional variant in TLR7 with systemic lupus erythematosus and rheumatoid arthritis in multiple ancestries
    • Deng Y, Zhao J, Tan WF. Association of a functional variant in TLR7 with systemic lupus erythematosus and rheumatoid arthritis in multiple ancestries. Arthritis Rheum 2011;63(Suppl 966):S246-7.
    • (2011) Arthritis Rheum , vol.63 , Issue.SUPPL. 966
    • Deng, Y.1    Zhao, J.2    Tan, W.F.3
  • 42
    • 33646368404 scopus 로고    scopus 로고
    • A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
    • Graham RR, Kozyrev SV, Baechler EC, et al. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 2006;38:550-5.
    • (2006) Nat Genet , vol.38 , pp. 550-555
    • Graham, R.R.1    Kozyrev, S.V.2    Baechler, E.C.3
  • 43
    • 79953707345 scopus 로고    scopus 로고
    • Association of a functional IRF7 variant with systemic lupus erythematosus
    • Fu Q, Zhao J, Qian X, et al. Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum 2011;63:749-54.
    • (2011) Arthritis Rheum , vol.63 , pp. 749-754
    • Fu, Q.1    Zhao, J.2    Qian, X.3
  • 44
    • 80055080962 scopus 로고    scopus 로고
    • Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus
    • Cunninghame Graham DS, Morris DL, et al. Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. PLoS Genet 2011;7:e1002341.
    • (2011) PLoS Genet , vol.7
    • Cunninghame Graham, D.S.1    Morris, D.L.2
  • 45
    • 84859491100 scopus 로고    scopus 로고
    • Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study
    • Lessard CJ, Adrianto I, Ice JA, et al. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet 2012;90:648-60.
    • (2012) Am J Hum Genet , vol.90 , pp. 648-660
    • Lessard, C.J.1    Adrianto, I.2    Ice, J.A.3
  • 46
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • DOI 10.1146/annurev.immunol.26.021607.090400
    • Tamura T, Yanai H, Savitsky D, et al. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol 2008;26:535-84. (Pubitemid 351600385)
    • (2008) Annual Review of Immunology , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 47
    • 70350650472 scopus 로고    scopus 로고
    • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
    • Gateva V, Sandling JK, Hom G, et al. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet 2009;41:1228-33.
    • (2009) Nat Genet , vol.41 , pp. 1228-1233
    • Gateva, V.1    Sandling, J.K.2    Hom, G.3
  • 48
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
    • Han JW, Zheng HF, Cui Y, et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 2009;41:1234-7.
    • (2009) Nat Genet , vol.41 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3
  • 49
    • 80155130254 scopus 로고    scopus 로고
    • Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study
    • Sanchez E, Comeau ME, Freedman BI, et al. Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study. Arthritis Rheum 2011;63:3493-501.
    • (2011) Arthritis Rheum , vol.63 , pp. 3493-3501
    • Sanchez, E.1    Comeau, M.E.2    Freedman, B.I.3
  • 50
    • 79959836816 scopus 로고    scopus 로고
    • A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus
    • Luo X, Yang W, Ye DQ, et al. A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. PLoS Genet 2011;7:e1002128.
    • (2011) PLoS Genet , vol.7
    • Luo, X.1    Yang, W.2    Ye, D.Q.3
  • 51
    • 65549124475 scopus 로고    scopus 로고
    • Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus
    • Jacob CO, Zhu J, Armstrong DL, et al. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci U S A 2009;106:6256-61.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6256-6261
    • Jacob, C.O.1    Zhu, J.2    Armstrong, D.L.3
  • 52
    • 50449111452 scopus 로고    scopus 로고
    • Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
    • Graham RR, Cotsapas C, Davies L, et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008;40:1059-61.
    • (2008) Nat Genet , vol.40 , pp. 1059-1061
    • Graham, R.R.1    Cotsapas, C.2    Davies, L.3
  • 53
    • 79952192654 scopus 로고    scopus 로고
    • Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus
    • Adrianto I, Wen F, Templeton A, et al. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet 2011;43:253-8.
    • (2011) Nat Genet , vol.43 , pp. 253-258
    • Adrianto, I.1    Wen, F.2    Templeton, A.3
  • 54
    • 79952787492 scopus 로고    scopus 로고
    • Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus
    • Sheng YJ, Gao JP, Li J, et al. Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus. Rheumatology (Oxford) 2011;50:682-8.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 682-688
    • Sheng, Y.J.1    Gao, J.P.2    Li, J.3
  • 55
    • 78751646484 scopus 로고    scopus 로고
    • A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles
    • Budarf ML, Goyette P, Boucher G, et al. A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles. Genes Immun 2011;12:51-8.
    • (2011) Genes Immun , vol.12 , pp. 51-58
    • Budarf, M.L.1    Goyette, P.2    Boucher, G.3
  • 56
    • 84864131309 scopus 로고    scopus 로고
    • A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus
    • Wang S, Adrianto I, Wiley GB, et al. A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun 2012;13:380-7.
    • (2012) Genes Immun , vol.13 , pp. 380-387
    • Wang, S.1    Adrianto, I.2    Wiley, G.B.3
  • 59
    • 77649206245 scopus 로고    scopus 로고
    • Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
    • Yang W, Shen N, Ye DQ, et al. Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet 2010;6:e1000841.
    • (2010) PLoS Genet , vol.6
    • Yang, W.1    Shen, N.2    Ye, D.Q.3
  • 60
    • 84857487791 scopus 로고    scopus 로고
    • A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese
    • Okada Y, Shimane K, Kochi Y, et al. A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet 2012;8:e1002455.
    • (2012) PLoS Genet , vol.8
    • Okada, Y.1    Shimane, K.2    Kochi, Y.3
  • 61
    • 68049110512 scopus 로고    scopus 로고
    • A polymorphism within IL21R confers risk for systemic lupus erythematosus
    • Webb R, Merrill JT, Kelly JA, et al. A polymorphism within IL21R confers risk for systemic lupus erythematosus. Arthritis Rheum 2009;60:2402-7.
    • (2009) Arthritis Rheum , vol.60 , pp. 2402-2407
    • Webb, R.1    Merrill, J.T.2    Kelly, J.A.3
  • 62
    • 84876297571 scopus 로고    scopus 로고
    • Risk alleles of SLE associated IL10 SNPs conferred differential binding to transcription factors
    • Sakurai D, Zhao J, Deng Y. Risk alleles of SLE associated IL10 SNPs conferred differential binding to transcription factors. Arthritis Rheum 2011;63(Suppl 966):S966.
    • (2011) Arthritis Rheum , vol.63 , Issue.SUPPL. 966
    • Sakurai, D.1    Zhao, J.2    Deng, Y.3
  • 63
    • 84862959180 scopus 로고    scopus 로고
    • Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase
    • Jacob CO, Eisenstein M, Dinauer MC, et al. Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A 2012;109:E59-67.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Jacob, C.O.1    Eisenstein, M.2    Dinauer, M.C.3
  • 65
    • 58849120030 scopus 로고    scopus 로고
    • A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus
    • Orru V, Tsai SJ, Rueda B, et al. A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus. Hum Mol Genet 2009;18:569-79.
    • (2009) Hum Mol Genet , vol.18 , pp. 569-579
    • Orru, V.1    Tsai, S.J.2    Rueda, B.3
  • 66
    • 77951758097 scopus 로고    scopus 로고
    • Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity
    • Crispin JC, Keenan BT, Finnell MD, et al. Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity. Arthritis Rheum 2010;62: 1431-7.
    • (2010) Arthritis Rheum , vol.62 , pp. 1431-1437
    • Crispin, J.C.1    Keenan, B.T.2    Finnell, M.D.3
  • 67
    • 78650862201 scopus 로고    scopus 로고
    • Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study
    • Lessard CJ, Adrianto I, Kelly JA, et al. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet 2011;88:83-91.
    • (2011) Am J Hum Genet , vol.88 , pp. 83-91
    • Lessard, C.J.1    Adrianto, I.2    Kelly, J.A.3
  • 68
    • 84867402906 scopus 로고    scopus 로고
    • Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries
    • Kim K, Brown EE, Choi CB, et al. Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis 2012;71:1809-14.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1809-1814
    • Kim, K.1    Brown, E.E.2    Choi, C.B.3
  • 70
    • 78650065026 scopus 로고    scopus 로고
    • Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus
    • Sanchez E, Webb RD, Rasmussen A, et al. Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus. Arthritis Rheum 2010;62:3722-9.
    • (2010) Arthritis Rheum , vol.62 , pp. 3722-3729
    • Sanchez, E.1    Webb, R.D.2    Rasmussen, A.3
  • 71
    • 84860224945 scopus 로고    scopus 로고
    • Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: A case-control study
    • Alonso-Perez E, Suarez-Gestal M, Calaza M, et al. Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study. Arthritis Res Ther 2012;14:R94.
    • (2012) Arthritis Res Ther , vol.14
    • Alonso-Perez, E.1    Suarez-Gestal, M.2    Calaza, M.3
  • 72
    • 77954995416 scopus 로고    scopus 로고
    • ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry
    • Kim-Howard X, Maiti AK, Anaya JM, et al. ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry. Ann Rheum Dis 2010;69:1329-32.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1329-1332
    • Kim-Howard, X.1    Maiti, A.K.2    Anaya, J.M.3
  • 73
    • 65549161855 scopus 로고    scopus 로고
    • ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai
    • Yang W, Zhao M, Hirankarn N, et al. ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai. Hum Mol Genet 2009;18:2063-70.
    • (2009) Hum Mol Genet , vol.18 , pp. 2063-2070
    • Yang, W.1    Zhao, M.2    Hirankarn, N.3
  • 74
    • 77949435272 scopus 로고    scopus 로고
    • Association of IRF5 polymorphisms with activation of the interferon alpha pathway
    • Rullo OJ, Woo JM, Wu H, et al. Association of IRF5 polymorphisms with activation of the interferon alpha pathway. Ann Rheum Dis 2010;69:611-17.
    • (2010) Ann Rheum Dis , vol.69 , pp. 611-617
    • Rullo, O.J.1    Woo, J.M.2    Wu, H.3
  • 76
    • 84860402042 scopus 로고    scopus 로고
    • HLA-DR3 restricted T cell epitope mimicry in induction of autoimmune response to lupus-associated antigen SmD
    • Deshmukh US, Sim DL, Dai C, et al. HLA-DR3 restricted T cell epitope mimicry in induction of autoimmune response to lupus-associated antigen SmD. J Autoimmun 2011;37:254-62.
    • (2011) J Autoimmun , vol.37 , pp. 254-262
    • Deshmukh, U.S.1    Sim, D.L.2    Dai, C.3
  • 77
    • 70449730890 scopus 로고    scopus 로고
    • STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk
    • Abelson AK, Delgado-Vega AM, Kozyrev SV, et al. STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk. Ann Rheum Dis 2009;68:1746-53.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1746-1753
    • Abelson, A.K.1    Delgado-Vega, A.M.2    Kozyrev, S.V.3
  • 78
    • 82955249081 scopus 로고    scopus 로고
    • Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK
    • Castillejo-Lopez C, Delgado-Vega AM, Wojcik J, et al. Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. Ann Rheum Dis 2012;71:136-42.
    • (2012) Ann Rheum Dis , vol.71 , pp. 136-142
    • Castillejo-Lopez, C.1    Delgado-Vega, A.M.2    Wojcik, J.3
  • 79
    • 84863026696 scopus 로고    scopus 로고
    • Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus
    • Hughes T, Adler A, Kelly JA, et al. Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum 2012;64:485-92.
    • (2012) Arthritis Rheum , vol.64 , pp. 485-492
    • Hughes, T.1    Adler, A.2    Kelly, J.A.3
  • 80
    • 84855295760 scopus 로고    scopus 로고
    • Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus
    • Zhou XJ, Lu XL, Nath SK, et al. Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus. Arthritis Rheum 2012;64:222-31.
    • (2012) Arthritis Rheum , vol.64 , pp. 222-231
    • Zhou, X.J.1    Lu, X.L.2    Nath, S.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.