메뉴 건너뛰기




Volumn 71, Issue 3, 2012, Pages 463-468

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

(28)  Niewold, Timothy B a   Kelly, Jennifer A b   Kariuki, Silvia N a   Franek, Beverly S a   Kumar, Akaash A a   Kaufman, Kenneth M b   Thomas, Kenaz b   Walker, Daniel b   Kamp, Stan b   Frost, Jacqueline M c   Wong, Andrew K d   Merrill, Joan T b,e   Alarcón Riquelme, Marta E b,f   Tikly, Mohammed c   Ramsey Goldman, Rosalind g,h   Reveille, John D g,i   Petri, Michelle A g,j   Edberg, Jeffrey C g,k   Kimberly, Robert P g,k   Alarcón, Graciela S g,k   more..


Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DOUBLE STRANDED DNA ANTIBODY; INTERFERON REGULATORY FACTOR 5; RO ANTIBODY;

EID: 84863115400     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-200463     Document Type: Article
Times cited : (130)

References (34)
  • 3
    • 2642528779 scopus 로고    scopus 로고
    • Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
    • DOI 10.1002/art.20254
    • Lövgren T, Eloranta ML, Båve U, et al. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 2004;50:1861-72. (Pubitemid 38725099)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.6 , pp. 1861-1872
    • Lovgren, T.1    Eloranta, M.-L.2    Bave, U.3    Alm, G.V.4    Ronnblom, L.5
  • 4
    • 0014613507 scopus 로고
    • Anti-DNA antibodies and renal lesions of patients with systemic lupus erythematosus
    • Koffler D, Agnello V, Carr RI, et al. Anti-DNA antibodies and renal lesions of patients with systemic lupus erythematosus. Transplant Proc 1969;1:933-8.
    • (1969) Transplant Proc , vol.1 , pp. 933-938
    • Koffler, D.1    Agnello, V.2    Carr, R.I.3
  • 5
    • 0035968246 scopus 로고    scopus 로고
    • Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
    • Barnes BJ, Moore PA, Pitha PM. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J Biol Chem 2001;276:23382-90.
    • (2001) J Biol Chem , vol.276 , pp. 23382-23390
    • Barnes, B.J.1    Moore, P.A.2    Pitha, P.M.3
  • 7
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
    • DOI 10.1126/science.1064890
    • Blanco P, Palucka AK, Gill M, et al. Induction of dendritic cell differentiation by IFNalpha in systemic lupus erythematosus. Science 2001;294:1540-3. (Pubitemid 33063928)
    • (2001) Science , vol.294 , Issue.5546 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 8
    • 34548438559 scopus 로고    scopus 로고
    • High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus
    • DOI 10.1038/sj.gene.6364408, PII 6364408
    • Niewold TB, Hua J, Lehman TJ, et al. High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun 2007;8:492-502. (Pubitemid 47365615)
    • (2007) Genes and Immunity , vol.8 , Issue.6 , pp. 492-502
    • Niewold, T.B.1    Hua, J.2    Lehman, T.J.A.3    Harley, J.B.4    Crow, M.K.5
  • 9
    • 0018775078 scopus 로고
    • Immune interferon in the circulation of patients with autoimmune disease
    • Hooks JJ, Moutsopoulos HM, Geis SA, et al. Immune interferon in the circulation of patients with autoimmune disease. N Engl J Med 1979;301:5-8. (Pubitemid 9226519)
    • (1979) New England Journal of Medicine , vol.301 , Issue.1 , pp. 5-8
    • Hooks, J.J.1    Moutsopoulos, H.M.2    Geis, S.A.3
  • 10
    • 79953677484 scopus 로고    scopus 로고
    • Network analysis of associations between serum interferon-a activity, autoantibodies, and clinical features in systemic lupus erythematosus
    • Weckerle CE, Franek BS, Kelly JA, et al. Network analysis of associations between serum interferon-a activity, autoantibodies, and clinical features in systemic lupus erythematosus. Arthritis Rheum 2011;63:1044-53.
    • (2011) Arthritis Rheum , vol.63 , pp. 1044-1053
    • Weckerle, C.E.1    Franek, B.S.2    Kelly, J.A.3
  • 11
    • 18644384042 scopus 로고    scopus 로고
    • Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease
    • DOI 10.1002/art.21031
    • Kirou KA, Lee C, George S, et al. Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis Rheum 2005;52:1491-503. (Pubitemid 40663941)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.5 , pp. 1491-1503
    • Kirou, K.A.1    Lee, C.2    George, S.3    Louca, K.4    Peterson, M.G.E.5    Crow, M.K.6
  • 12
    • 0025057503 scopus 로고
    • Possible induction of systemic lupus erythematosus by interferon alpha-treatment in a patient with a malignant carcinoid tumour
    • Rönnblom LE, Alm GV, Oberg KE. Possible induction of systemic lupus erythematosus by interferon-alpha treatment in a patient with a malignant carcinoid tumour. J Intern Med 1990;227:207-10. (Pubitemid 20075945)
    • (1990) Journal of Internal Medicine , vol.227 , Issue.3 , pp. 207-210
    • Ronnblom, L.E.1    Oberg, K.E.2    Alm, G.V.3
  • 13
    • 17544373868 scopus 로고    scopus 로고
    • Systemic lupus erythematosus arising during interferon-alpha therapy for cryoglobulinemic vasculitis associated with hepatitis C
    • DOI 10.1007/s10067-004-1024-2
    • Niewold TB, Swedler WI. Systemic lupus erythematosus arising during interferon-alpha therapy for cryoglobulinemic vasculitis associated with hepatitis C. Clin Rheumatol 2005;24:178-81. (Pubitemid 40552976)
    • (2005) Clinical Rheumatology , vol.24 , Issue.2 , pp. 178-181
    • Niewold, T.B.1    Swedler, W.I.2
  • 14
    • 83455169554 scopus 로고    scopus 로고
    • Interferon Alpha as a Primary Pathogenic Factor in Human Lupus
    • Published Online First:16 September 2011, doi:10.1089/jir.2011.0071
    • Niewold TB. Interferon Alpha as a Primary Pathogenic Factor in Human Lupus. J Interferon Cytokine Res 2011; Published Online First:16 September 2011, doi:10.1089/jir.2011.0071.
    • (2011) J Interferon Cytokine Res
    • Niewold, T.B.1
  • 15
    • 75749110600 scopus 로고    scopus 로고
    • Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients
    • Salloum R, Franek BS, Kariuki SN, et al. Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients. Arthritis Rheum 2010;62:553-61.
    • (2010) Arthritis Rheum , vol.62 , pp. 553-561
    • Salloum, R.1    Franek, B.S.2    Kariuki, S.N.3
  • 16
    • 49449104525 scopus 로고    scopus 로고
    • Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients
    • Niewold TB, Kelly JA, Flesch MH, et al. Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients. Arthritis Rheum 2008;58:2481-7.
    • (2008) Arthritis Rheum , vol.58 , pp. 2481-2487
    • Niewold, T.B.1    Kelly, J.A.2    Flesch, M.H.3
  • 17
    • 59849096879 scopus 로고    scopus 로고
    • Cutting edge: Autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo
    • Kariuki SN, Kirou KA, MacDermott EJ, et al. Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo. J Immunol 2009;182:34-8.
    • (2009) J Immunol , vol.182 , pp. 34-38
    • Kariuki, S.N.1    Kirou, K.A.2    MacDermott, E.J.3
  • 18
    • 76549136591 scopus 로고    scopus 로고
    • Genetic regulation of serum cytokines in systemic lupus erythematosus
    • Kariuki SN, Niewold TB. Genetic regulation of serum cytokines in systemic lupus erythematosus. Transl Res 2010;155:109-17.
    • (2010) Transl Res , vol.155 , pp. 109-117
    • Kariuki, S.N.1    Niewold, T.B.2
  • 19
    • 77954877255 scopus 로고    scopus 로고
    • Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus
    • Kariuki SN, Franek BS, Kumar AA, et al. Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus. Arthritis Res Ther 2010;12:R151.
    • (2010) Arthritis Res Ther , vol.12
    • Kariuki, S.N.1    Franek, B.S.2    Kumar, A.A.3
  • 20
    • 79956141306 scopus 로고    scopus 로고
    • Interferon regulatory factors in human lupus pathogenesis
    • Salloum R, Niewold TB. Interferon regulatory factors in human lupus pathogenesis. Transl Res 2011;157:326-31.
    • (2011) Transl Res , vol.157 , pp. 326-331
    • Salloum, R.1    Niewold, T.B.2
  • 22
    • 0020436689 scopus 로고
    • The 1982 revised criteria for the classification of systemic lupus erythrematosus
    • DOI 10.1002/art.1780251101
    • Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7. (Pubitemid 13221242)
    • (1982) Arthritis and Rheumatism , vol.25 , Issue.11 , pp. 1271-1277
    • Tan, E.M.1    Cohen, A.S.2    Fries, J.F.3
  • 24
    • 33745034931 scopus 로고    scopus 로고
    • Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies
    • DOI 10.1002/art.21890
    • Hua J, Kirou K, Lee C, et al. Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies. Arthritis Rheum 2006;54:1906-16. (Pubitemid 43877940)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.6 , pp. 1906-1916
    • Hua, J.1    Kirou, K.2    Lee, C.3    Crow, M.K.4
  • 25
    • 0033047408 scopus 로고    scopus 로고
    • Failure to detect antiviral activity in serum and plasma of healthy individuals displaying high activity in ELISA for IFN-alpha and IFN-beta
    • DOI 10.1089/107999099313901
    • Jabs WJ, Hennig C, Zawatzky R, et al. Failure to detect antiviral activity in serum and plasma of healthy individuals displaying high activity in ELISA for IFN-alpha and IFN-beta. J Interferon Cytokine Res 1999;19:463-9. (Pubitemid 29269936)
    • (1999) Journal of Interferon and Cytokine Research , vol.19 , Issue.5 , pp. 463-469
    • Jabs, W.J.1    Hennig, C.2    Zawatzky, R.3    Kirchner, H.4
  • 26
    • 39749158486 scopus 로고    scopus 로고
    • Serum type I interferon activity is dependent on maternal diagnosis in anti-SSA/Ro-positive mothers of children with neonatal lupus
    • DOI 10.1002/art.23191
    • Niewold TB, Rivera TL, Buyon JP, et al. Serum type I interferon activity is dependent on maternal diagnosis in anti-SSA/Ro-positive mothers of children with neonatal lupus. Arthritis Rheum 2008;58:541-6. (Pubitemid 351294888)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.2 , pp. 541-546
    • Niewold, T.B.1    Rivera, T.L.2    Buyon, J.P.3    Crow, M.K.4
  • 27
    • 66449121844 scopus 로고    scopus 로고
    • Elevated serum interferon-alpha activity in juvenile dermatomyositis: Associations with disease activity at diagnosis and after thirty-six months of therapy
    • Niewold TB, Kariuki SN, Morgan GA, et al. Elevated serum interferon-alpha activity in juvenile dermatomyositis: associations with disease activity at diagnosis and after thirty-six months of therapy. Arthritis Rheum 2009;60:1815-24.
    • (2009) Arthritis Rheum , vol.60 , pp. 1815-1824
    • Niewold, T.B.1    Kariuki, S.N.2    Morgan, G.A.3
  • 29
    • 76249125968 scopus 로고    scopus 로고
    • IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- Mouse models of systemic lupus erythematosus
    • Richez C, Yasuda K, Bonegio RG, et al. IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus. J Immunol 2010;184:796-806.
    • (2010) J Immunol , vol.184 , pp. 796-806
    • Richez, C.1    Yasuda, K.2    Bonegio, R.G.3
  • 30
    • 73349095052 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells regulate autoreactive B cell activation via soluble factors and in a cell-to-cell contact manner
    • Ding C, Cai Y, Marroquin J, et al. Plasmacytoid dendritic cells regulate autoreactive B cell activation via soluble factors and in a cell-to-cell contact manner. J Immunol 2009;183:7140-9.
    • (2009) J Immunol , vol.183 , pp. 7140-7149
    • Ding, C.1    Cai, Y.2    Marroquin, J.3
  • 31
    • 33746238512 scopus 로고    scopus 로고
    • Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice
    • DOI 10.1002/eji.200535734
    • Brummel R, Roberts TL, Stacey KJ, et al. Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice. Eur J Immunol 2006;36:1951-62. (Pubitemid 44089060)
    • (2006) European Journal of Immunology , vol.36 , Issue.7 , pp. 1951-1962
    • Brummel, R.1    Roberts, T.L.2    Stacey, K.J.3    Lenert, P.4
  • 32
    • 44949149145 scopus 로고    scopus 로고
    • Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus
    • Taylor KE, Remmers EF, Lee AT, et al. Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus. PLoS Genet 2008;4:e1000084.
    • (2008) PLoS Genet , vol.4
    • Taylor, K.E.1    Remmers, E.F.2    Lee, A.T.3
  • 33
    • 80051619284 scopus 로고    scopus 로고
    • Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-a and serologic autoimmunity in lupus patients
    • Robinson T, Kariuki SN, Franek BS, et al. Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-a and serologic autoimmunity in lupus patients. J Immunol 2011;187:1298-303.
    • (2011) J Immunol , vol.187 , pp. 1298-1303
    • Robinson, T.1    Kariuki, S.N.2    Franek, B.S.3
  • 34
    • 34447273288 scopus 로고    scopus 로고
    • The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden
    • Kokkonen H, Johansson M, Innala L, et al. The PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden. Arthritis Res Ther 2007;9:R56.
    • (2007) Arthritis Res Ther , vol.9
    • Kokkonen, H.1    Johansson, M.2    Innala, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.