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Volumn 30, Issue 6, 2013, Pages 441-452

Delayed post-injury administration of riluzole is neuroprotective in a preclinical rodent model of cervical spinal cord injury

Author keywords

[No Author keywords available]

Indexed keywords

R 116; RILUZOLE; UNCLASSIFIED DRUG;

EID: 84876270838     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2012.2622     Document Type: Article
Times cited : (76)

References (39)
  • 1
    • 0035893632 scopus 로고    scopus 로고
    • Epidemiology, demographics, and pathophysiology of acute spinal cord injury
    • Sekhon LH, and Fehlings MG. (2001). Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine 26, S2-12.
    • (2001) Spine , vol.26
    • Sekhon, L.H.1    Fehlings, M.G.2
  • 2
    • 0026326449 scopus 로고
    • Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms
    • Tator CH, and Fehlings MG. (1991). Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J Neurosurg 75, 15-26.
    • (1991) J Neurosurg , vol.75 , pp. 15-26
    • Tator, C.H.1    Fehlings, M.G.2
  • 3
    • 3042816808 scopus 로고    scopus 로고
    • The role of ex-citotoxicity in secondary mechanisms of spinal cord injury: A review with an emphasis on the implications for white matter degeneration
    • Park E, Velumian AA, and Fehlings MG. (2004). The role of ex-citotoxicity in secondary mechanisms of spinal cord injury: A review with an emphasis on the implications for white matter degeneration. J Neurotrauma 21, 754-774.
    • (2004) J Neurotrauma , vol.21 , pp. 754-774
    • Park, E.1    Velumian, A.A.2    Fehlings, M.G.3
  • 5
    • 0036454326 scopus 로고    scopus 로고
    • Secondary injury mechanisms of spinal cord trauma: A novel therapeutic approach for the management of secondary pathophysiology with the sodium channel blocker riluzole
    • L. McKerracher, G. Doucet, S. Rossignol (eds), Elsevier Science B.V.
    • Schwartz G, and Fehlings MG. (2002). Secondary injury mechanisms of spinal cord trauma: A novel therapeutic approach for the management of secondary pathophysiology with the sodium channel blocker riluzole. In: Progress in Brain Research. L. McKerracher, G. Doucet, S. Rossignol (eds), Elsevier Science B.V., pps. 177-190.
    • (2002) Progress in Brain Research , pp. 177-190
    • Schwartz, G.1    Fehlings, M.G.2
  • 7
    • 0034698248 scopus 로고    scopus 로고
    • Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes
    • Azbill RD, Mu X, and Springer JE. (2000). Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes. Brain Res 871, 175-180.
    • (2000) Brain Res , vol.871 , pp. 175-180
    • Azbill, R.D.1    Mu, X.2    Springer, J.E.3
  • 8
    • 0029753270 scopus 로고    scopus 로고
    • The pharmacology and mechanism of action of ri-luzole
    • Doble A. (1996). The pharmacology and mechanism of action of ri-luzole. Neurology 47, S233-241.
    • (1996) Neurology , vol.47
    • Doble, A.1
  • 9
    • 33846951494 scopus 로고    scopus 로고
    • A comparison of the glutamate relase inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain
    • Coderre TJ, Kumar N, Lefebrvre CD, and Yu JS. (2007). A comparison of the glutamate relase inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain. J Neurochem 100, 1289-1299.
    • (2007) J Neurochem , vol.100 , pp. 1289-1299
    • Coderre, T.J.1    Kumar, N.2    Lefebrvre, C.D.3    Yu, J.S.4
  • 10
    • 0030930824 scopus 로고    scopus 로고
    • Rapid calpain i activation and cytoskeletal protein degradation following traumatic spinal cord injury: Attenuation with riluzole pretreatment
    • Springer JE, Azbill RD, Kennedy Se, George J, and Geddes JW. (1997). Rapid calpain I activation and cytoskeletal protein degradation following traumatic spinal cord injury: Attenuation with riluzole pretreatment. J Neurochem 69, 1592-1600.
    • (1997) J Neurochem , vol.69 , pp. 1592-1600
    • Springer, J.E.1    Azbill, R.D.2    Se, K.3    George, J.4    Geddes, J.W.5
  • 11
    • 0029976154 scopus 로고    scopus 로고
    • The effect of riluzole on post-traumatic spinal cord injury in the rat
    • Stutzman JM, Pratt J, Boraud T, and Gross C. (1996). The effect of riluzole on post-traumatic spinal cord injury in the rat. Neuroreport 7, 387-392.
    • (1996) Neuroreport , vol.7 , pp. 387-392
    • Stutzman, J.M.1    Pratt, J.2    Boraud, T.3    Gross, C.4
  • 12
    • 0034867539 scopus 로고    scopus 로고
    • Evaluation of the neuropro-tective effects of sodium channel blockers after spinal cord injury: Improved behavioral and neuroanatomical recovery with riluzole
    • Schwartz G, and Fehlings MG. (2001). Evaluation of the neuropro-tective effects of sodium channel blockers after spinal cord injury: Improved behavioral and neuroanatomical recovery with riluzole. J Neurosurg 94, 245-256.
    • (2001) J Neurosurg , vol.94 , pp. 245-256
    • Schwartz, G.1    Fehlings, M.G.2
  • 13
    • 0034617464 scopus 로고    scopus 로고
    • Riluzole improves measure of oxidative stress following traumatic spinal cord injury
    • Mu X, Azbill Rd, and Springer JE. (2000). Riluzole improves measure of oxidative stress following traumatic spinal cord injury. Brain Res 870, 66-72.
    • (2000) Brain Res , vol.870 , pp. 66-72
    • Mu, X.1    Rd, A.2    Springer, J.E.3
  • 15
    • 72049098587 scopus 로고    scopus 로고
    • Autonomic function following cervical spinal cord injury
    • Krassioukov A. (2009). Autonomic function following cervical spinal cord injury. Respir Physiol Neurobiol 169, 157-164.
    • (2009) Respir Physiol Neurobiol , vol.169 , pp. 157-164
    • Krassioukov, A.1
  • 16
    • 0029012783 scopus 로고
    • The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury
    • Fehlings MG, and Tator CH. (1995). The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury. Exp Neurol 132, 220-228.
    • (1995) Exp Neurol , vol.132 , pp. 220-228
    • Fehlings, M.G.1    Tator, C.H.2
  • 17
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso DM, Beattie MS, and Bresnahan JC. (1995). A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neu-rotrauma 12, 1-21.
    • (1995) J. Neu-rotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 18
    • 33645455547 scopus 로고    scopus 로고
    • Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury
    • Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Morshead CM, and Fehlings MG. (2006). Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J Neurosci 26, 3377-3389.
    • (2006) J Neurosci , vol.26 , pp. 3377-3389
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3    Morshead, C.M.4    Fehlings, M.G.5
  • 19
    • 76149105178 scopus 로고    scopus 로고
    • Synergistic effects of transplanted adult neural stem-progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord
    • Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Schut D, and Fehlings MG. (2010). Synergistic effects of transplanted adult neural stem-progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. J Neurosci 30, 1657-1676.
    • (2010) J Neurosci , vol.30 , pp. 1657-1676
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3    Schut, D.4    Fehlings, M.G.5
  • 20
    • 0036444138 scopus 로고    scopus 로고
    • Chronic pain after clip-compression injury of the rat spinal cord
    • Bruce JC, Oatway MA, and Weaver LC. (2002). Chronic pain after clip-compression injury of the rat spinal cord. Exp Neurol 178, 33-48.
    • (2002) Exp Neurol , vol.178 , pp. 33-48
    • Bruce, J.C.1    Oatway, M.A.2    Weaver, L.C.3
  • 21
    • 12744277932 scopus 로고    scopus 로고
    • Anti-CD11d integrin antibody treatment restores normal se-rotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord
    • Oatway MA, Chen Y, Bruce JC, Dekaban GA, and Weaver LC. (2005). Anti-CD11d integrin antibody treatment restores normal se-rotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord. J Neurosci 25, 637-647.
    • (2005) J Neurosci , vol.25 , pp. 637-647
    • Oatway, M.A.1    Chen, Y.2    Bruce, J.C.3    Dekaban, G.A.4    Weaver, L.C.5
  • 22
    • 34147198436 scopus 로고    scopus 로고
    • Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions
    • Matsumoto H, Kumon Y, Watanabe H, Ohnishi T, Shudou M, Ii C, Takahashi H, Imai Y, and Tanaka J. (2007). Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions. J Neurosci Res 85, 994-1009.
    • (2007) J Neurosci Res , vol.85 , pp. 994-1009
    • Matsumoto, H.1    Kumon, Y.2    Watanabe, H.3    Ohnishi, T.4    Shudou, M.5    Ii, C.6    Takahashi, H.7    Imai, Y.8    Tanaka, J.9
  • 23
    • 67649400664 scopus 로고    scopus 로고
    • Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury
    • Baptiste DC, Austin JW, Zhao W, Nahirny A, Sugita S, and Fehlings MG. (2009). Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury. J Neuropathol Exp Neurol 68, 661-667.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 661-667
    • Baptiste, D.C.1    Austin, J.W.2    Zhao, W.3    Nahirny, A.4    Sugita, S.5    Fehlings, M.G.6
  • 25
    • 0032909284 scopus 로고    scopus 로고
    • Increased calpain l-mediated proteolysis, and preferential loss of dephosphorylated NF200, following traumatic spinal cord injury
    • Schumacher PA, Eubanks JH, and Fehlings MG. (1999). Increased calpain l-mediated proteolysis, and preferential loss of dephosphorylated NF200, following traumatic spinal cord injury. Neuroscience 91, 733-744.
    • (1999) Neuroscience , vol.91 , pp. 733-744
    • Schumacher, P.A.1    Eubanks, J.H.2    Fehlings, M.G.3
  • 26
    • 0030025964 scopus 로고    scopus 로고
    • Mechanisms of secondary injury to spinal cord axons in vitro: Role of Na +, Na(+)-K(+)-AT-Pase, the Na(+)-H+ exchanger, and the Na(+)-Ca2+ exchanger
    • Agrawal SK, and Fehlings MG. (1996). Mechanisms of secondary injury to spinal cord axons in vitro: role of Na +, Na(+)-K(+)-AT-Pase, the Na(+)-H+ exchanger, and the Na(+)-Ca2+ exchanger. J Neurosci 16, 545-552.
    • (1996) J Neurosci , vol.16 , pp. 545-552
    • Agrawal, S.K.1    Fehlings, M.G.2
  • 27
    • 20444386558 scopus 로고    scopus 로고
    • General mechanisms of axonal damage and its prevention
    • Stys PK. (2005). General mechanisms of axonal damage and its prevention. J Neurol Sci 233, 3-13.
    • (2005) J Neurol Sci , vol.233 , pp. 3-13
    • Stys, P.K.1
  • 29
    • 0036366102 scopus 로고    scopus 로고
    • Anti-epileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity
    • Farber NB, Jiang XP, Heinkel C, and Nemmers B. (2002). Anti-epileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity. Mol Psychiatry 7, 726-733.
    • (2002) Mol Psychiatry , vol.7 , pp. 726-733
    • Farber, N.B.1    Jiang, X.P.2    Heinkel, C.3    Nemmers, B.4
  • 30
    • 37849003885 scopus 로고    scopus 로고
    • Neuroprotection and repair
    • Palace J. (2008). Neuroprotection and repair. J Neurol Sci 265, 21-25.
    • (2008) J Neurol Sci , vol.265 , pp. 21-25
    • Palace, J.1
  • 31
    • 52649149895 scopus 로고    scopus 로고
    • Riluzole in psychiatry: A systematic review of the literature
    • Zarate CA, and Manji HK. (2008). Riluzole in psychiatry: A systematic review of the literature. Expert Opin Drug Metab Toxicol 4, 1223-1234.
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 1223-1234
    • Zarate, C.A.1    Manji, H.K.2
  • 32
    • 0030468988 scopus 로고    scopus 로고
    • Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat
    • McIntosh TK, Smith DH, Voddi M, Perri BR, and Stutzmann JM. (1996). Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. J Neurotrauma 13, 767-780.
    • (1996) J Neurotrauma , vol.13 , pp. 767-780
    • McIntosh, T.K.1    Smith, D.H.2    Voddi, M.3    Perri, B.R.4    Stutzmann, J.M.5
  • 33
    • 0031739040 scopus 로고    scopus 로고
    • Role of group i metabotropic glutamate receptors in traumatic spinal cord white matter injury
    • Agrawal SK, Theriault E, and Fehlings MG. (1998). Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury. J Neurotrauma 15, 929-941.
    • (1998) J Neurotrauma , vol.15 , pp. 929-941
    • Agrawal, S.K.1    Theriault, E.2    Fehlings, M.G.3
  • 34
    • 0025907224 scopus 로고
    • Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord
    • Liu D, Thangnipon W, and McAdoo DJ. (1991). Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain Res 547, 344-348.
    • (1991) Brain Res , vol.547 , pp. 344-348
    • Liu, D.1    Thangnipon, W.2    McAdoo, D.J.3
  • 36
    • 84856728400 scopus 로고    scopus 로고
    • Expression of inflammatory cytokines following acute spinal cord injury in a rodent model
    • Stammers AT, Liu J, and Kwon BK. (2012). Expression of inflammatory cytokines following acute spinal cord injury in a rodent model. J Neurosci Res 90, 782-790.
    • (2012) J Neurosci Res , vol.90 , pp. 782-790
    • Stammers, A.T.1    Liu, J.2    Kwon, B.K.3
  • 37
    • 0034680980 scopus 로고    scopus 로고
    • Efficient testing of motor function in spinal cord injured rats
    • Metz GA, Merkler D, Dietz V, Schwab ME, and Fouad K. (2000). Efficient testing of motor function in spinal cord injured rats. Brain Res 883, 165-177.
    • (2000) Brain Res , vol.883 , pp. 165-177
    • Metz, G.A.1    Merkler, D.2    Dietz, V.3    Schwab, M.E.4    Fouad, K.5
  • 38
    • 1942425492 scopus 로고    scopus 로고
    • Behavioral testing after spinal cord injury: Con-gruities, complexities, and controversies
    • Basso DM. (2004). Behavioral testing after spinal cord injury: Con-gruities, complexities, and controversies. J Neurotrauma 21, 395-404.
    • (2004) J Neurotrauma , vol.21 , pp. 395-404
    • Basso, D.M.1
  • 39
    • 63849340879 scopus 로고    scopus 로고
    • Current status of acute spinal cord injury pathophysiology and emerging therapies: Promise on the horizon
    • Rowland JW, Hawryluk GW, Kwon B, and Fehlings MG. (2008). Current status of acute spinal cord injury pathophysiology and emerging therapies: Promise on the horizon. Neurosurg Focus 25, E2.
    • (2008) Neurosurg Focus , vol.25
    • Rowland, J.W.1    Hawryluk, G.W.2    Kwon, B.3    Fehlings, M.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.