Design, synthesis, and pharmacological evaluation of fluorescent and biotinylated antagonists of ρ1 GABAC receptors

ACS Medicinal Chemistry Letters

Volumn 4, Issue 4, 2013, Pages 402-407

  Gavande, Navnath ^a   Kim, Hye Lim ^a   Doddareddy, Munikumar R ^a   Johnston, Graham A R ^b   Chebib, Mary ^a   Hanrahan, Jane R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b University of Sydney   (Australia)

Author keywords

CNS related disorders; fluorescent and biotinylated probes; GABAC antagonists; homology modeling and docking; Human 1 GABAC receptors

Indexed keywords

4 AMINOBUTYRIC ACID C RECEPTOR BLOCKING AGENT; LIGAND;

ARTICLE; BIOTINYLATION; CONJUGATE; DRUG SELECTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SYNTHESIS;

EID: 84876266305     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300476v     Document Type: Article

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