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Inhibition assays with ABL1 (H396P), ABL1 (M351T), ABL1 (Q252H), ABL1 (T315I), ABL1 (Y253F), ABL2/ARG and P38α/MAPK14 were carried out by Reaction Biology Corporation, Malvern, PA, USA
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Inhibition assays with ABL1 (H396P), ABL1 (M351T), ABL1 (Q252H), ABL1 (T315I), ABL1 (Y253F), ABL2/ARG and P38α/MAPK14 were carried out by Reaction Biology Corporation, Malvern, PA, USA.
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In vitro human microsomal stability and parallel artificial membrane permeability assay (PAMPA) assays were carried out by Cyprotex Discovery Ltd. Macclesfield, Cheshire, U.K.
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In vitro human microsomal stability and parallel artificial membrane permeability assay (PAMPA) assays were carried out by Cyprotex Discovery Ltd., Macclesfield, Cheshire, U.K.
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