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Volumn 40, Issue 15, 1997, Pages 2304-2313

Designing combinatorial library mixtures using a genetic algorithm

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ARTICLE; CHEMICAL STRUCTURE; DNA LIBRARY; GENE CLUSTER; GENETIC VARIABILITY; SYNTHESIS;

EID: 0030815955     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970033y     Document Type: Article
Times cited : (105)

References (32)
  • 2
    • 15644368828 scopus 로고
    • Analyzing Molecular Diversity by Database Clustering
    • American Chemical Society: Washington, DC, 124-COMP
    • Dunbar, J. Analyzing Molecular Diversity by Database Clustering. Abstracts of Papers of the American Chemical Society, American Chemical Society: Washington, DC, 1994; Vol. 208, 124-COMP.
    • (1994) Abstracts of Papers of the American Chemical Society , vol.208
    • Dunbar, J.1
  • 4
    • 0028953765 scopus 로고
    • Measuring Diversity: Experimental Design of Combinatorial Libraries for Drug Discovery
    • Martin, E. J.; Blaney, J. M.; Siani, M. S.; Spellmeyer, D. C.; Wong, A. K.; Moos, W. H. Measuring Diversity: Experimental Design of Combinatorial Libraries for Drug Discovery J. Med. Chem. 1995, 38, 1431-1436.
    • (1995) J. Med. Chem. , vol.38 , pp. 1431-1436
    • Martin, E.J.1    Blaney, J.M.2    Siani, M.S.3    Spellmeyer, D.C.4    Wong, A.K.5    Moos, W.H.6
  • 6
    • 0002647926 scopus 로고    scopus 로고
    • Rapid Quantification of Molecular Diversity for Selective Database Acquisition
    • Turner, D. B.; Tyrrell, S. M.; Willett, P. Rapid Quantification of Molecular Diversity For Selective Database Acquisition. J. Chem. Inf. Comput. Sci. 1997, 37, 18-22.
    • (1997) J. Chem. Inf. Comput. Sci. , vol.37 , pp. 18-22
    • Turner, D.B.1    Tyrrell, S.M.2    Willett, P.3
  • 10
    • 0342645323 scopus 로고    scopus 로고
    • Use of Structure-Activity Data to Compare Structure-Based Clustering Methods and Descriptors for Use in Compound Selection
    • Brown, R. D.; Martin, Y. C. Use of Structure-Activity Data to Compare Structure-Based Clustering Methods and Descriptors for Use in Compound Selection. J. Chem. Inf. Comput. Sci. 1996, 36, 572-584.
    • (1996) J. Chem. Inf. Comput. Sci. , vol.36 , pp. 572-584
    • Brown, R.D.1    Martin, Y.C.2
  • 11
    • 15644365890 scopus 로고    scopus 로고
    • Laboratory for Molecular Graphics and Theoretical Modelling, College of Pharmacy, University of Texas at Austin, TX
    • DiverseSolutions v2.0.1; Laboratory for Molecular Graphics and Theoretical Modelling, College of Pharmacy, University of Texas at Austin, TX.
    • DiverseSolutions V2.0.1
  • 13
    • 0030191461 scopus 로고    scopus 로고
    • Molecular Diversity in Chemical Databases: Comparison of Medicinal Chemistry and Knowledge Bases and Databases of Commercially Available Compounds
    • Cummins, D. J.; Andrews, C. W.; Bentley, J. A.; Cory, M. Molecular Diversity in Chemical Databases: Comparison of Medicinal Chemistry and Knowledge Bases and Databases of Commercially Available Compounds. J. Chem. Inf. Comput. Sci. 1996, 36, 750-763.
    • (1996) J. Chem. Inf. Comput. Sci. , vol.36 , pp. 750-763
    • Cummins, D.J.1    Andrews, C.W.2    Bentley, J.A.3    Cory, M.4
  • 14
    • 15644369831 scopus 로고    scopus 로고
    • Special Report - Combinatorial Chemistry
    • February 12
    • Special Report - Combinatorial Chemistry. C&EN 1996, February 12, 28-73.
    • (1996) C&EN , pp. 28-73
  • 15
    • 77956780169 scopus 로고    scopus 로고
    • Application of Mass Spectrometry for Characterizing and Identifying Ligands from Combinatorial Libraries
    • Bristol, J. A., Ed.; Academic Press: San Diego, CA
    • Loo, J. A.; DeJohn, D. E. Application of Mass Spectrometry for Characterizing and Identifying Ligands from Combinatorial Libraries. In Annual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press: San Diego, CA, 1996; Vol. 31.
    • (1996) Annual Reports in Medicinal Chemistry , vol.31
    • Loo, J.A.1    DeJohn, D.E.2
  • 16
    • 77956743376 scopus 로고    scopus 로고
    • Solid-Phase Synthesis: Applications to Combinatorial Libraries
    • Bristol, J. A., Ed.; Academic Press: San Diego, CA
    • Choong, I. C.; Ellman, J. A. Solid-Phase Synthesis: Applications to Combinatorial Libraries. In Annual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press: San Diego, CA, 1996; Vol. 31.
    • (1996) Annual Reports in Medicinal Chemistry , vol.31
    • Choong, I.C.1    Ellman, J.A.2
  • 21
    • 0029878670 scopus 로고    scopus 로고
    • Application of genetic algorithms to combinatorial synthesis - A computational approach to lead identification and lead optimization
    • Singh, J.; Ator, M. A.; Jaeger, E. P.; Allen, M. P.; Whipple, D. A.; Soloweij, J. E.; Chowdhary, S.; Treasurywala, A. M. Application of genetic algorithms to combinatorial synthesis - a computational approach to lead identification and lead optimization. J. Am. Chem. Soc. 1996, 118, 1669-1676.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 1669-1676
    • Singh, J.1    Ator, M.A.2    Jaeger, E.P.3    Allen, M.P.4    Whipple, D.A.5    Soloweij, J.E.6    Chowdhary, S.7    Treasurywala, A.M.8
  • 22
    • 0029271228 scopus 로고
    • Using a genetic algorithm to suggest combinatorial libraries
    • Sheridan, R. P.; Kearsley, S. K. Using a genetic algorithm to suggest combinatorial libraries. J. Chem. Inf. Comput. Sci. 1995, 35, 310-320.
    • (1995) J. Chem. Inf. Comput. Sci. , vol.35 , pp. 310-320
    • Sheridan, R.P.1    Kearsley, S.K.2
  • 23
    • 0342918166 scopus 로고
    • A Genetic Algorithm Optimising Biological Activity of Combinatorial Compound Libraries
    • Weber, L.; Wallbaum, S.; Broger, C.; Gubernator, K. A Genetic Algorithm Optimising Biological Activity of Combinatorial Compound Libraries. Angew. Chem. 1995, 107, 2453-2454.
    • (1995) Angew. Chem. , vol.107 , pp. 2453-2454
    • Weber, L.1    Wallbaum, S.2    Broger, C.3    Gubernator, K.4
  • 24
    • 15644363319 scopus 로고    scopus 로고
    • Project Library; MDL Information Systems, Inc., San Leandro, CA
    • Project Library; MDL Information Systems, Inc., San Leandro, CA.
  • 25
    • 15644372617 scopus 로고    scopus 로고
    • Chem-X; Chemical Design Ltd., Chipping Norton, Oxfordshire, U.K.
    • Chem-X; Chemical Design Ltd., Chipping Norton, Oxfordshire, U.K.
  • 26
    • 15644378509 scopus 로고    scopus 로고
    • Tmftalk. Part of the Daylight contributed code directory; Dr. B. Rohde, Ciba-Geigy, Basel, Switzerland
    • Tmftalk. Part of the Daylight contributed code directory; Dr. B. Rohde, Ciba-Geigy, Basel, Switzerland.
  • 29
    • 0003389370 scopus 로고
    • The Genitor Algorithm and Selection Pressure: Why rand-based allocation of reproductive trials is best
    • Schaffer, J. D., Ed.; Morgan Kaufmann: San Francisco, CA
    • Whitely, L. D. The Genitor Algorithm and Selection Pressure: Why rand-based allocation of reproductive trials is best. In Proceedings of the Third International Conference on Genetic Algorithms; Schaffer, J. D., Ed.; Morgan Kaufmann: San Francisco, CA, 1989.
    • (1989) Proceedings of the Third International Conference on Genetic Algorithms
    • Whitely, L.D.1
  • 31
    • 15644364339 scopus 로고    scopus 로고
    • Available Chemicals Directory; MDL Information Systems, Inc., San Leandro, CA
    • Available Chemicals Directory; MDL Information Systems, Inc., San Leandro, CA.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.