IGFBP5 mediates high glucoseinduced cardiac fibroblast activation

Journal of Molecular Endocrinology

Volumn 50, Issue 3, 2013, Pages 291-303

  Song, Seung Eun ^a   Kim, Yong Woon ^a   Kim, Jong Yeon ^a   Lee, Dong Hyup ^a   Kim, Jae Ryong ^a   Park, So Young ^a  

^a Yeungnam University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; COLLAGEN TYPE 3; GELATINASE A; GELATINASE B; GLUCOSE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT PROTEIN; RECOMBINANT SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; STREPTOZOCIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CARDIAC FIBROBLAST; CELL COUNT; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; FEMALE; FIBROBLAST; GLUCOSE BLOOD LEVEL; HEART; HEART MUSCLE CELL; MALE; MEDIATOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; SINGLE DRUG DOSE; STREPTOZOCIN DIABETES;

EID: 84876190382     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-12-0194     Document Type: Article

References (53)

1. Amaar YG, Thompson GR, Linkhart TA, Chen ST, Baylink DJ & Mohan S 2002 Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2). Journal of Biological Chemistry 277 12053-12060. (doi:10.1074/jbc.M110872200)
2. Amaar YG, Baylink DJ & Mohan S 2005 Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation. Journal of Bone and Mineral Research 20 1430-1439. (doi:10.1359/JBMR.050311)
3. Banerjee I, Fuseler JW, Price RL, Borg TK & Baudino TA 2007 Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. American Journal of Physiology. Heart and Circulatory Physiology 293 H1883-H1891. (doi:10.1152/ajpheart. 00514.2007)
4. Baurand A, Zelarayan L, Betney R, Gehrke C, Dunger S, Noack C, Busjahn A, Huelsken J, Taketo MM, Birchmeier W et al. 2007 b-Catenin downregulation is required for adaptive cardiac remodeling. Circulation Research 100 1353-1362. (doi:10.1161/01.RES.0000266605.63681.5a)
5. Berfield AK, Hansen KM & Abrass CK 2006 Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5. American Journal of Physiology. Cell Physiology 291 C589-C599. (doi:10.1152/ajpcell.00623.2005)
6. Boudina S & Abel ED 2010 Diabetic cardiomyopathy, causes and effects. Reviews in Endocrine & Metabolic Disorders 11 31-39. (doi:10.1007/s11154-010-9131-7)
7. Busik JV, Mohr S & Grant MB 2008 Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators. Diabetes 57 1952-1965. (doi:10.2337/db07-1520)
8. Butt AJ, Dickson KA, Jambazov S & Baxter RC 2005 Enhancement of tumor necrosis factor-a-induced growth inhibition by insulin-like growth factor-binding protein-5 (IGFBP-5), but not IGFBP-3 in human breast cancer cells. Endocrinology 146 3113-3122. (doi:10.1210/en.2004-1408)
9. Cesi V, Vitali R, Tanno B, Giuffrida ML, Sesti F, Mancini C & Raschella G 2004 Insulin-like growth factor binding protein 5: contribution to growth and differentiation of neuroblastoma cells. Annals of the New York Academy of Sciences 1028 59-68. (doi:10.1196/annals.1322.007)
10. Cobb LJ, Salih DA, Gonzalez I, Tripathi G, Carter EJ, Lovett F, Holding C & Pell JM 2004 Partitioning of IGFBP-5 actions in myogenesis: IGFindependent anti-apoptotic function. Journal of Cell Science 117 1737-1746. (doi:10.1242/jcs.01028)
11. Cook SA, Matsui T, Li L & Rosenzweig A 2002 Transcriptional effects of chronic Akt activation in the heart. Journal of Biological Chemistry 277 22528-22533. (doi:10.1074/jbc.M201462200)
12. Feghali CA & Wright TM 1999 Identification of multiple, differentially expressed messenger RNAs in dermal fibroblasts from patients with systemic sclerosis. Arthritis and Rheumatism 42 1451-1457. (doi:10.1002/1529-0131(199907)42:7!1451::AID-ANR19O3.0.CO;2-6)
13. Han HJ, Kang CW and Park SH 2006 Tissue-specific regulation of insulin-like growth factors and insulin-like growth factor binding proteins in male diabetic rats in vivo and in vitro. Clinical and Experimental Pharmacology & Physiology 33 1172-1179. (doi:10.1111/j.1440-1681.2006.04495.x)
14. Hung PS, Kao SY, Liu CJ, Tu HF, Wu CH & Lin SC 2008 Insulin-like growth factor binding protein-5 enhances the migration and differentiation of gingival epithelial cells. Journal of Periodontal Research 43 673-680. (doi:10.1111/j.1600-0765.2007.01070.x)
15. Hwa V, Oh Y & Rosenfeld RG 1999 The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocrine Reviews 20 761-787. (doi:10.1210/er.20.6.761)
16. Kiepe D, Ciarmatori S, Hoeflich A, Wolf E & Tonshoff B 2005 Insulin-like growth factor (IGF)-I stimulates cell proliferation and induces IGF binding protein (IGFBP)-3 and IGFBP-5 gene expression in cultured growth plate chondrocytes via distinct signaling pathways. Endocrinology 146 3096-3104. (doi:10.1210/en.2005-0324)
17. Kim KS, Seu YB, Baek SH, Kim MJ, Kim KJ, Kim JH & Kim JR 2007 Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism. Molecular Biology of the Cell 18 4543-4552. (doi:10.1091/mbc.E07-03-0280)
18. Kim JE, Song SE, Kim YW, Kim JY, Park SC, Park YK, Baek SH, Lee IK & Park SY 2010 Adiponectin inhibits palmitate-induced apoptosis through suppression of reactive oxygen species in endothelial cells: involvement of cAMP/protein kinase A and AMP-activated protein kinase. Journal of Endocrinology 207 35-44. (doi:10.1677/JOE-10-0093)
19. Kluge A, Zimmermann R, Munkel B, Verdouw PD, Schaper J & Schaper W 1995 Insulin-like growth factor II is an experimental stress inducible gene in a porcine model of brief coronary occlusions. Cardiovascular Research 29 708-716. (doi:10.1016/S00008-6363(96)88644-5)
20. Kuemmerle JF & Zhou H 2002 Insulin-like growth factor-binding protein-5 (IGFBP-5) stimulates growth and IGF-I secretion in human intestinal smooth muscle by Ras-dependent activation of p38 MAP kinase and Erk1/2 pathways. Journal of Biological Chemistry 277 20563-20571. (doi:10.1074/jbc.M200885200)
21. Kuo WW, Wang WJ, Tsai CY, Way CL, Hsu HH & Chen LM 2012 Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFkB signaling via attenuating ROS generation. International Journal of Cardiology. In press. (doi:10.1016/j.ijcard.2012.09.080)
22. Liu W, Schoenkerman A & Lowe WL Jr 2000 Activation of members of the mitogen-activated protein kinase family by glucose in endothelial cells. American Journal of Physiology. Endocrinology and Metabolism 279 E782-E790.
23. Maile LA, Allen LB, Hanzaker CF, Gollahon KA, Dunbar P & Clemmons DR 2010 Glucose regulation of thrombospondin and its role in the modulation of smooth muscle cell proliferation. Experimental Diabetes Research 2010. (doi:10.1155/2010/617052)
24. Mohan S & Baylink DJ 2002 IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. Journal of Endocrinology 175 19-31. (doi:10.1677/joe.0.1750019)
25. Mohan S, Nakao Y, Honda Y, Landale E, Leser U, Dony C, Lang K & Baylink DJ 1995 Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells. Journal of Biological Chemistry 270 20424-20431. (doi:10.1074/jbc.270.35.20424)
26. Neumann S, Huse K, Semrau R, Diegeler A, Gebhardt R, Buniatian GH & Scholz GH 2002 Aldosterone and D-glucose stimulate the proliferation of human cardiac myofibroblasts in vitro. Hypertension 39 756-760. (doi:10.1161/hy0302.105295)
27. Park IS, Kiyomoto H, Alvarez F, Xu YC, Abboud HE & Abboud SL 1998 Preferential expression of insulin-like growth factor binding proteins-1, -3, and -5 during early diabetic renal hypertrophy in rats. American Journal of Kidney Diseases 32 1000-1010. (doi:10.1016/S0272- 6386(98)70075-7)
28. Pilewski JM, Liu L, Henry AC, Knauer AV & Feghali-Bostwick CA 2005 Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition. American Journal of Pathology 166 399-407. (doi:10.1016/ S0002-9440(10)62263-8)
29. Ren H, Yin P & Duan C 2008 IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop. Journal of Cell Biology 182 979-991. (doi:10.1083/jcb.200712110)
30. Russell SB, Russell JD, Trupin KM, Gayden AE, Opalenik SR, Nanney LB, Broquist AH, Raju L & Williams SM 2010 Epigenetically altered wound healing in keloid fibroblasts. Journal of Investigative Dermatology 130 2489-2496. (doi:10.1038/jid.2010.162)
31. Schaeffer V, Hansen KM, Morris DR & Abrass CK 2010 Reductions in laminin b2 mRNA translation are responsible for impaired IGFBP- 5-mediated mesangial cell migration in the presence of high glucose. American Journal of Physiology. Renal Physiology 298 F314-F322. (doi:10.1152/ajprenal.00483.2009)
32. Schedlich LJ, Young TF, Firth SM & Baxter RC 1998 Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells. Journal of Biological Chemistry 273 18347-18352. (doi:10.1074/jbc.273.29.18347)
33. Schneider MR, Wolf E, Hoeflich A & Lahm H 2002 IGF-binding protein-5: flexible player in the IGF system and effector on its own. Journal of Endocrinology 172 423-440. (doi:10.1677/joe.0.1720423)
34. Shimizu M, Umeda K, Sugihara N, Yoshio H, Ino H, Takeda R, Okada Y & Nakanishi I 1993 Collagen remodelling in myocardia of patients with diabetes. Journal of Clinical Pathology 46 32-36. (doi:10.1136/jcp.46.1.32)
35. Singh VP, Baker KM & Kumar R 2008a Activation of the intracellular renin- angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production. American Journal of Physiology. Heart and Circulatory Physiology 294 H1675-H1684. (doi:10.1152/ajpheart. 91493.2007)
36. Singh VP, Le B, Khode R, Baker KM & Kumar R 2008b Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. Diabetes 57 3297-3306. (doi:10.2337/db08-0805)
37. Singh AB, Guleria RS, Nizamutdinova IT, Baker KM & Pan J 2012 High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling. Journal of Cellular Physiology 227 2632-2644. (doi:10.1002/jcp.23005)
38. Sokolovic A, Sokolovic M, Boers W, Elferink RP & Bosma PJ 2010 Insulinlike growth factor binding protein 5 enhances survival of LX2 human hepatic stellate cells. Fibrogenesis & Tissue Repair 3 3. (doi:10.1186/1755- 1536-3-3)
39. Souders CA, Bowers SL & Baudino TA 2009 Cardiac fibroblast: the renaissance cell. Circulation Research 105 1164-1176. (doi:10.1161/ CIRCRESAHA.109.209809)
40. Su Y, Wagner ER, Luo Q, Huang J, Chen L, He BC, Zuo GW, Shi Q, Zhang BQ, Zhu G et al. 2011 Insulin-like growth factor binding protein 5 suppresses tumor growth and metastasis of human osteosarcoma. Oncogene 30 3907-3917. (doi:10.1038/onc.2011.97)
41. Tang M, Zhang W, Lin H, Jiang H, Dai H & Zhang Y 2007 High glucose promotes the production of collagen types I and III by cardiac fibroblasts through a pathway dependent on extracellular-signalregulated kinase 1/2. Molecular and Cellular Biochemistry 301 109-114. (doi:10.1007/s11010-006-9401-6)
42. Tang D, He B, Zheng ZG, Wang RS, Gu F, Duan TT, Cheng HQ & Zhu Q 2010 Inhibitory effects of two major isoflavonoids in Radix Astragali on high glucose-induced mesangial cells proliferation and AGEs-induced endothelial cells apoptosis. Planta Medica 77 729-732. (doi:10.1055/s-0030-1250628)
43. Tang M, Zhou F, Zhang W, Guo Z, Shang Y, Lu H, Lu R, Zhang Y, Chen Y & Zhong M 2011 The role of thrombospondin-1-mediated TGF-b1 on collagen type III synthesis induced by high glucose. Molecular and Cellular Biochemistry 346 49-56. (doi:10.1007/s11010-010-0590-7)
44. Tanno B, Vitali R, De Arcangelis D, Mancini C, Eleuteri P, Dominici C & Raschella G 2006 Bim-dependent apoptosis follows IGFBP-5 downregulation in neuroblastoma cells. Biochemical and Biophysical Research Communications 351 547-552. (doi:10.1016/j.bbrc.2006.10.062)
45. Tokudome T, Horio T, Yoshihara F, Suga S, Kawano Y, Kohno M & Kangawa K 2004 Direct effects of high glucose and insulin on protein synthesis in cultured cardiac myocytes and DNA and collagen synthesis in cardiac fibroblasts. Metabolism 53 710-715. (doi:10.1016/j.metabol.2004.01.006)
46. Tonner E, Barber MC, Allan GJ, Beattie J, Webster J, Whitelaw CB & Flint DJ 2002 Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice. Development 129 4547-4557.
47. Wei L 2011 Immunological aspect of cardiac remodeling: T lymphocyte subsets in inflammation-mediated cardiac fibrosis. Experimental and Molecular Pathology 90 74-78. (doi:10.1016/j.yexmp.2010.10.004)
48. Xin X, Hou YT, Li L, Schmiedlin-Ren P, Christman GM, Cheng HL, Bitar KN & Zimmermann EM 2004 IGF-I increases IGFBP-5 and collagen a1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cells. American Journal of Physiology. Gastrointestinal and Liver Physiology 286 G777-G783. (doi:10.1152/ajpgi.00293.2003)
49. Yasuoka H, Jukic DM, Zhou Z, Choi AM & Feghali-Bostwick CA 2006a Insulin-like growth factor binding protein 5 induces skin fibrosis: a novel murine model for dermal fibrosis. Arthritis and Rheumatism 54 3001-3010. (doi:10.1002/art.22084)
50. Yasuoka H, Zhou Z, Pilewski JM, Oury TD, Choi AM & Feghali-Bostwick CA 2006b Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration. American Journal of Pathology 169 1633-1642. (doi:10.2353/ajpath.2006.060501)
51. Yasuoka H, Yamaguchi Y & Feghali-Bostwick CA 2009 The pro-fibrotic factor IGFBP-5 induces lung fibroblast and mononuclear cellmigration. American Journal of Respiratory Cell and Molecular Biology 41 179-188. (doi:10.1165/rcmb.2008-0211OC)
52. Zhen D, Chen Y & Tang X 2010 Metformin reverses the deleterious effects of high glucose on osteoblast function. Journal of Diabetes and its Complications 24 334-344. (doi:10.1016/j.jdiacomp.2009.05.002)
53. Zoungas S & Patel A 2010 Cardiovascular outcomes in type 2 diabetes: the impact of preventative therapies. Annals of the New York Academy of Sciences 1212 29-40. (doi:10.1111/j.1749-6632.2010.05837.x)