Acetylation of Human TCF4 (TCF7L2) Proteins Attenuates Inhibition by the HBP1 Repressor and Induces a Conformational Change in the TCF4::DNA Complex

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Elfert, Susanne ^a   Weise, Andreas ^a   Bruser, Katja ^a   Biniossek, Martin L ^a   Jägle, Sabine ^a   Senghaas, Niklas ^a   Hecht, Andreas ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; BETA CATENIN; HISTONE ACETYLTRANSFERASE PCAF; HMG BOX PROTEIN 1; LYMPHOID ENHANCER FACTOR 1; LYSINE; REPRESSOR PROTEIN; T CELL FACTOR PROTEIN; T CELL FACTOR PROTEIN 4 E2; UNCLASSIFIED DRUG; WNT PROTEIN; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA; HBP1 PROTEIN, HUMAN; HIGH MOBILITY GROUP PROTEIN; ISOPROTEIN; TCF4 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ACETYLATION; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL EXPRESSION SYSTEM; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA PROTEIN COMPLEX; EMBRYO; ENZYME SUBSTRATE; EXPRESSION VECTOR; FEMALE; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; IMMUNODETECTION; INHIBITION KINETICS; MUTATIONAL ANALYSIS; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TANDEM MASS SPECTROMETRY; TRANSACTIVATION; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CONFORMATION; ENZYME SPECIFICITY; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN TERTIARY STRUCTURE; TRANSCRIPTION INITIATION;

BACTERIA (MICROORGANISMS); VERTEBRATA;

ACETYLATION; AMINO ACID SEQUENCE; ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA CATENIN; CREB-BINDING PROTEIN; DNA; HEK293 CELLS; HIGH MOBILITY GROUP PROTEINS; HUMANS; LYSINE; MICE; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84876182037     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061867     Document Type: Article

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