Functional Investigation of NCI-H460-Inducible Myofibroblasts on the Chemoresistance to VP-16 with a Microfluidic 3D Co-Culture Device

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Hao, Yuanyuan ^a   Zhang, Lichuan ^b   He, Jiarui ^a   Guo, Zhe ^a   Ying, Li ^a   Xu, Zhiyun ^a   Zhang, Jianing ^a   Lu, Jianxin ^c   Wang, Qi ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b DALIAN UNIVERSITY   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN GEL; DEXTRAN; ETOPOSIDE; FLUORESCEIN ISOTHIOCYANATE; GLUCOSE REGULATED PROTEIN 78;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL ACTIVATION; CELL CONTACT; CELL FUNCTION; CELL INTERACTION; CELL TRANSFORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DOUBLE LAYER MICROFLUIDIC COCULTURE DEVICE; DRUG RESISTANCE; DRUG SENSITIVITY; FETUS; GENERAL MEDICAL DEVICE; HUMAN; HUMAN CELL; INJECTION PUMP; LUNG CANCER; MYOFIBROBLAST; PROTEIN EXPRESSION; PUMP; TUMOR MICROENVIRONMENT; UPREGULATION;

CELL LINE; COCULTURE TECHNIQUES; ETOPOSIDE; FIBROBLASTS; HUMANS; MICROFLUIDICS; MYOFIBROBLASTS;

EID: 84876167429     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061754     Document Type: Article

References (41)

1. Califano R, Abidin AZ, Peck R, Faivre-Finn C, Lorigan P, (2012) Management of small cell lung cancer: recent developments for optimal care. Drugs 72: 471-490.
2. De Wever O, Mareel M, (2003) Role of tissue stroma in cancer cell invasion. J Pathol 200: 429-447.
3. Kalluri R, Zeisberg M, (2006) Fibroblasts in cancer. Nat Rev Cancer 6: 392-401.
4. Anderberg C, Li H, Fredriksson L, Andrae J, Betsholtz C, et al. (2009) Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res 69: 369-378.
5. Bhowmick NA, Neilson EG, Moses HL, (2004) Stromal fibroblasts in cancer initiation and progression. Nature 432: 332-337.
6. Micke P, Ostman A, (2004) Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy? Lung Cancer 45Suppl 2: S163-175.
7. Loeffler M, Kruger JA, Niethammer AG, Reisfeld RA, (2006) Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J Clin Invest 116: 1955-1962.
8. Buess M, Nuyten DS, Hastie T, Nielsen T, Pesich R, et al. (2007) Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer. Genome Biol 8: R191.
9. Giannoni E, Bianchini F, Masieri L, Serni S, Torre E, et al. (2010) Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness. Cancer Res 70: 6945-6956.
10. West J, Becker M, Tombrink S, Manz A, (2008) Micro total analysis systems: latest achievements. Anal Chem 80: 4403-4419.
11. Mark D, Haeberle S, Roth G, von Stetten F, Zengerle R, (2010) Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications. Chem Soc Rev 39: 1153-1182.
12. Kaji H, Yokoi T, Kawashima T, Nishizawa M, (2009) Controlled cocultures of HeLa cells and human umbilical vein endothelial cells on detachable substrates. Lab Chip 9: 427-432.
13. Huang CP, Lu J, Seon H, Lee AP, Flanagan LA, et al. (2009) Engineering microscale cellular niches for three-dimensional multicellular co-cultures. Lab Chip 9: 1740-1748.
14. Hsu TH, Xiao JL, Tsao YW, Kao YL, Huang SH, et al. (2011) Analysis of the paracrine loop between cancer cells and fibroblasts using a microfluidic chip. Lab Chip 11: 1808-1814.
15. Wong AP, Perez-Castillejos R, Christopher Love J, Whitesides GM, (2008) Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments. Biomaterials 29: 1853-1861.
16. El-Ali J, Sorger PK, Jensen KF, (2006) Cells on chips. Nature 442: 403-411.
17. Tilles AW, Baskaran H, Roy P, Yarmush ML, Toner M, (2001) Effects of oxygenation and flow on the viability and function of rat hepatocytes cocultured in a microchannel flat-plate bioreactor. Biotechnol Bioeng 73: 379-389.
18. Oh S, (2008) Thick single-layer positive photoresist mold and poly (dimethylsiloxane)(PDMS) dry etching for the fabrication of a glass-PDMS-glass microfluidic device. Journal of Micromechanics and Microengineering 18: 115025.
19. Zhao L, Wang Z, Fan S, Meng Q, Li B, et al. (2010) Chemotherapy resistance research of lung cancer based on micro-fluidic chip system with flow medium. Biomedical microdevices 12: 325-332.
20. Zhang L, Wang J, Zhao L, Meng Q, Wang Q, (2010) Analysis of chemoresistance in lung cancer with a simple microfluidic device. Electrophoresis 31: 3763-3770.
21. Ermakova SP, Kang BS, Choi BY, Choi HS, Schuster TF, et al. (2006) (-)- Epigallocatechin Gallate Overcomes Resistance to Etoposide-Induced Cell Death by Targeting the Molecular Chaperone Glucose-Regulated Protein 78. Cancer research 66: 9260-9269.
22. Fischbach C, Kong HJ, Hsiong SX, Evangelista MB, Yuen W, et al. (2009) Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement. Science Signalling 106: 399.
23. Sasaki T, Takagi M, Soma T, Yoshida T, (2003) Analysis of hematopoietic microenvironment containing spatial development of stromal cells in nonwoven fabrics. Journal of bioscience and bioengineering 96: 76-78.
24. Walker GM, Zeringue HC, Beebe DJ, (2004) Microenvironment design considerations for cellular scale studies. Lab Chip 4: 91-97.
25. Khademhosseini A, Langer R, Borenstein J, Vacanti JP, (2006) Microscale technologies for tissue engineering and biology. Proceedings of the National Academy of Sciences of the United States of America 103: 2480-2487.
26. El-Ali J, Sorger PK, Jensen KF, (2006) Cells on chips. Nature 442: 403-411.
27. Abbott A, (2003) Cell culture: biology's new dimension. Nature 424: 870-872.
28. Håkanson M, Textor M, Charnley M, (2011) Engineered 3D environments to elucidate the effect of environmental parameters on drug response in cancer. Integrative Biology 3: 31-38.
29. Ranganathan AC, Zhang L, Adam AP, Aguirre-Ghiso JA, (2006) Functional Coupling of p38-Induced Up-regulation of BiP and Activation of RNA-Dependent Protein Kinase-Like Endoplasmic Reticulum Kinase to Drug Resistance of Dormant Carcinoma Cells. Cancer research 66: 1702-1711.
30. Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, et al. (2003) Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors. Journal of Biological Chemistry 278: 20915-20924.
31. Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, et al. (2008) Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells. Molecular Cancer Research 6: 1268-1275.
32. Siyan W, Feng Y, Lichuan Z, Jiarui W, Yingyan W, et al. (2009) Application of microfluidic gradient chip in the analysis of lung cancer chemotherapy resistance. Journal of pharmaceutical and biomedical analysis 49: 806-810.
33. Lee AS, (2001) The glucose-regulated proteins: stress induction and clinical applications. Trends in biochemical sciences 26: 504-510.
34. Yu ZF, Luo H, Fu W, Mattson MP, (1999) The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Experimental neurology 155: 302-314.
35. Herzog TJ, (2004) Recurrent Ovarian Cancer How Important Is It to Treat to Disease Progression? Clinical cancer research 10: 7439-7449.
36. Hande K, (1998) Etoposide: four decades of development of a topoisomerase II inhibitor. European journal of cancer (Oxford, England: 1990) 34: 1514.
37. Gosky D, Chatterjee S, (2003) Down-regulation of topoisomerase IIα is caused by up-regulation of GRP78. Biochemical and biophysical research communications 300: 327-332.
38. Rao RV, Hermel E, Castro-Obregon S, del Rio G, Ellerby LM, et al. (2001) Coupling endoplasmic reticulum stress to the cell death program mechanism of caspase activation. Journal of Biological Chemistry 276: 33869-33874.
39. Fu Y, Li J, Lee AS, (2007) GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis. Cancer research 67: 3734-3740.
40. Wang Q, He Z, Zhang J, Wang Y, Wang T, et al. (2005) Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance. Cancer detection and prevention 29: 544-551.
41. Ying-yan W, Tao W, Xin L, Hong-wei G, Bing-cheng L, et al. (2008) The analysis of chemotherapy resistance in human lung cancer cell line with microchip-based system. Biomedical microdevices 10: 429-435.