Analysis of hematopoietic microenvironment containing spatial development of stromal cells in nonwoven fabrics

Journal of Bioscience and Bioengineering

Volumn 96, Issue 1, 2003, Pages 76-78

  Sasaki, Takahide ^a   Takagi, Mutsumi ^a   Soma, Toshihiro ^b   Yoshida, Toshiomi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b MINAMI OSAKA GENERAL HOSPITAL   (Japan)

Author keywords

Hematopoiesis; Microenvironment; Nonwoven fabric; Porous carrier; Stromal cell; Three dimensional culture

Indexed keywords

CELL CULTURE; CELLS; PROTEINS; RNA;

SUPERNATANTS;

NONWOVEN FABRICS;

CYTOKINE; LAMININ; MESSENGER RNA; STEM CELL FACTOR; THROMBOPOIETIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CULTURE; EXTRACELLULAR MATRIX; FEMUR; GENE EXPRESSION; HEMATOPOIESIS; MALE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; STEM CELL; STROMA CELL; TIBIA;

ANIMALIA;

EID: 0041919435     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.96.76     Document Type: Article

References (12)

1. Nakahata, T.: Cord blood transplantation and ex vivo expansion of hematopoietic stem cells. Rinsho Byori, 110 (Suppl.), 54-62 (1999).
2. Zandstra, P. W., Conneally, E., Petzer, A. L., Piret, J. M., and Eaves, C. J.: Cytokine manipulation of primitive human hematopoietic cell self-renewal. Proc. Natl. Acad. Sci. USA, 94, 4698-4703 (1997).
3. Takagi, M., Sasaki, T., and Yoshida, T.: Spatial development of the cultivation of a bone marrow stromal cell line in porous carriers. Cytotechnology, 31, 225-231 (1999).
4. Dexter, T. M., Allen, T. D., Lajtha, L. G., Schofield, R., and Lord, B. I.: Stimulation of differentiation and proliferation of haemopoietic cells in vitro. J. Cell. Physiol., 82, 461-473 (1973).
5. Sasaki, T., Takagi, M., Soma, T., and Yoshida, T.: 3D culture of murine hematopoietic cells with spatial development of stromal cells in nonwoven fabrics. Cytotherapy, 4, 285-291 (2001).
6. - cells and stroma induces a soluble activity that specifically increases primitive hematopoietic cell production. Exp. Hematol., 27, 734-741 (1999).
7. Ogawa, M., Nishikawa, S., Ikuta, K., Yamamura, F., Naito, M., Takahashi, K., and Nishikawa, S.: B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST2: B cell progenitor develops first in the embryonal body rather than in the yolk sac. EMBO J., 7, 1337-1343 (1988).
8. Klein, G.: The extracellular matrix of the hematopoietic microenvironment. Experientia, 51, 914-926 (1995).
9. Siler, U., Seiffert, M., Puch, S., Richards, A., Torok-Storb, B., Muller, C. A., Sorokin, L., and Klein, G.: Characterization and functional analysis of laminin isoforms in human bone marrow. Blood, 96, 4194-4203 (2000).
10. Gu, Y., Sorokin, L., Durbeej, M., Hjalt, T., Jonsson, J. I., and Ekblom, M.: Characterization of bone marrow laminins and identification of α5-containing laminins as adhesive proteins for multipotent hematopoietic FDCP-Mix cells. Blood, 93, 2533-2542 (1998).
11. Banu, N., Rosenzweig, M., Kim, H., Bagley, J., and Pykett, M.: Cytokine-augmented culture of haematopoietic progenitor cells in a novel three-dimensional cell growth matrix. Cytokine, 13, 349-358 (2001).
12. Gupta, P., Oegema, T. R., Jr., Brazil, J. J., Dudek, A. Z., Slungaard, A., and Verfaillie, C. M.: Structurally specific heparan sulfates support primitive human hematopoiesis by formation of a multimolecular stem cell niche. Blood, 92, 4641-4651 (1998).