Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia

European Journal of Pharmacology

Volumn 707, Issue 1-3, 2013, Pages 78-86

  Spaccapelo, Luca ^a   Galantucci, Maria ^a   Neri, Laura ^a   Contri, Miranda ^a   Pizzala, Roberto ^b   D'Amico, Roberto ^a   Ottani, Alessandra ^a   Sandrini, Maurizio ^a   Zaffe, Davide ^a   Giuliani, Daniela ^a   Guarini, Salvatore ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Cerebral ischemia; Melanocortin MC4 receptor; Molecular mechanism; Neurogenesis; Repair factor; Signaling pathway; Sonic hedgehog; Wnt 3A

Indexed keywords

AFAMELANOTIDE; BETA CATENIN; DOUBLECORTIN; INTERLEUKIN 10; MELANOCORTIN 4 RECEPTOR; PROTEIN ZIF268; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT3A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DRUG MECHANISM; GERBIL; HIPPOCAMPUS; LEARNING; MALE; MEMORY; MOLECULAR MECHANICS; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ALPHA-MSH; ANIMALS; BRAIN ISCHEMIA; CELL PROLIFERATION; DENTATE GYRUS; DISEASE MODELS, ANIMAL; GERBILLINAE; HEDGEHOG PROTEINS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; NEUROPEPTIDES; RECEPTOR, MELANOCORTIN, TYPE 4; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION; WNT SIGNALING PATHWAY; WNT3A PROTEIN;

EID: 84876161346     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.03.030     Document Type: Article

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