Treatment of cerebral ischemia with melanocortins acting at MC 4 receptors induces marked neurogenesis and long-lasting functional recovery

Acta Neuropathologica

Volumn 122, Issue 4, 2011, Pages 443-453

  Giuliani, Daniela ^a   Zaffe, Davide ^a   Ottani, Alessandra ^a   Spaccapelo, Luca ^a   Galantucci, Maria ^a   Minutoli, Letteria ^c   Bitto, Alessandra ^c   Irrera, Natasha ^c   Contri, Miranda ^a   Altavilla, Domenica ^c   Botticelli, Annibale R ^b   Squadrito, Francesco ^c   Guarini, Salvatore ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

Cerebral ischemia; Functional recovery; Melanocortins; Neurogenesis; Time window

Indexed keywords

ALPHA INTERMEDIN[4 NORLEUCINE 7 DEXTROPHENYLALANINE]; DOUBLECORTIN; MELANOCORTIN; MELANOCORTIN 4 RECEPTOR; NEURON SPECIFIC NUCLEAR PROTEIN; UNCLASSIFIED DRUG; WNT3A PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COMMON CAROTID ARTERY; CONTROLLED STUDY; CONVALESCENCE; DENTATE GYRUS; DRUG EFFECT; GERBIL; HIPPOCAMPUS; LEARNING; MALE; MEMORY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETROSPECTIVE STUDY; SIGNAL TRANSDUCTION; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; GERBILLINAE; MALE; MELANOCORTINS; NERVE DEGENERATION; NEUROGENESIS; RECEPTOR, MELANOCORTIN, TYPE 4; RECOVERY OF FUNCTION; TIME FACTORS;

EID: 80054695075     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0873-4     Document Type: Article

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