메뉴 건너뛰기




Volumn 84, Issue 4, 2013, Pages 535-544

Toll-like receptor 2 knockdown modulates interleukin (IL)-6 and IL-8 but not stromal derived factor-1 (SDF-1/CXCL12) in human periodontal ligament and gingival fibroblasts

Author keywords

Cytokines; Fibroblasts; Gene silencing; Porphyromonas gingivalis; Toll like receptor 2; Toll like receptor 4

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 84876149747     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2012.120177     Document Type: Article
Times cited : (45)

References (43)
  • 1
    • 0029088834 scopus 로고
    • Inflammatory cytokine gene expression in human periodontal ligament fibroblasts stimulated with bacterial lipopolysaccharides
    • Yamaji Y, Kubota T, Sasaguri K, et al. Inflammatory cytokine gene expression in human periodontal ligament fibroblasts stimulated with bacterial lipopolysaccharides. Infect Immun 1995;63:3576-3581.
    • (1995) Infect Immun , vol.63 , pp. 3576-3581
    • Yamaji, Y.1    Kubota, T.2    Sasaguri, K.3
  • 2
    • 0035834584 scopus 로고    scopus 로고
    • Heterogeneous expression of Toll-like receptor 4 and downregulation of Toll-like receptor 4 expression on human gingival fibroblasts by Porphyromonas gingivalis lipopolysaccharide
    • Wang PL, Oido-Mori M, Fujii T, et al. Heterogeneous expression of Toll-like receptor 4 and downregulation of Toll-like receptor 4 expression on human gingival fibroblasts by Porphyromonas gingivalis lipopolysaccharide. Biochem Biophys Res Commun 2001;288: 863-867.
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 863-867
    • Wang, P.L.1    Oido-Mori, M.2    Fujii, T.3
  • 3
    • 0034647798 scopus 로고    scopus 로고
    • Toll-like receptor 4-mediated signal pathway induced by Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts
    • Wang PL, Azuma Y, Shinohara M, Ohura K. Toll-like receptor 4-mediated signal pathway induced by Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts. Biochem Biophys Res Commun 2000;273:1161-1167.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 1161-1167
    • Wang, P.L.1    Azuma, Y.2    Shinohara, M.3    Ohura, K.4
  • 4
    • 33947356654 scopus 로고    scopus 로고
    • Functional TLRs and NODs in human gingival fibroblasts
    • Uehara A, Takada H. Functional TLRs and NODs in human gingival fibroblasts. J Dent Res 2007;86:249-254.
    • (2007) J Dent Res , vol.86 , pp. 249-254
    • Uehara, A.1    Takada, H.2
  • 5
    • 80053561363 scopus 로고    scopus 로고
    • Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts
    • Tang L, Zhou XD, Wang Q, et al. Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts. Arch Oral Biol 2011;56:1064-1072.
    • (2011) Arch Oral Biol , vol.56 , pp. 1064-1072
    • Tang, L.1    Zhou, X.D.2    Wang, Q.3
  • 6
    • 33748871535 scopus 로고    scopus 로고
    • New insights into the regulation of TLR signaling
    • Miggin SM, O'Neill LA. New insights into the regulation of TLR signaling. J Leukoc Biol 2006;80:220-226.
    • (2006) J Leukoc Biol , vol.80 , pp. 220-226
    • Miggin, S.M.1    O'Neill, L.A.2
  • 8
    • 33748308787 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Uematsu S, Akira S. Toll-like receptors and innate immunity. J Mol Med (Berl) 2006;84:712-725.
    • (2006) J Mol Med (Berl) , vol.84 , pp. 712-725
    • Uematsu, S.1    Akira, S.2
  • 9
    • 17544373870 scopus 로고    scopus 로고
    • Role of p38 in nitric oxide synthase and cyclooxygenase expression, and nitric oxide and PGE2 synthesis in human gingival fibroblasts stimulated with lipopolysaccharides
    • Gutiérrez-Venegas G, Maldonado-Frías S, Ontiveros- Granados A, Kawasaki-Cárdenas P. Role of p38 in nitric oxide synthase and cyclooxygenase expression, and nitric oxide and PGE2 synthesis in human gingival fibroblasts stimulated with lipopolysaccharides. Life Sci 2005;77:60-73.
    • (2005) Life Sci , vol.77 , pp. 60-73
    • Gutiérrez-Venegas, G.1    Maldonado-Frías, S.2    Ontiveros-Granados, A.3    Kawasaki-Cárdenas, P.4
  • 10
    • 23044438378 scopus 로고    scopus 로고
    • CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease
    • Hosokawa Y, Hosokawa I, Ozaki K, et al. CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease. Clin Exp Immunol 2005;141:467-474.
    • (2005) Clin Exp Immunol , vol.141 , pp. 467-474
    • Hosokawa, Y.1    Hosokawa, I.2    Ozaki, K.3
  • 11
    • 5044249323 scopus 로고    scopus 로고
    • Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalis
    • Hashimoto M, Asai Y, Ogawa T. Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalis. Int Immunol 2004;16:1431-1437.
    • (2004) Int Immunol , vol.16 , pp. 1431-1437
    • Hashimoto, M.1    Asai, Y.2    Ogawa, T.3
  • 12
    • 72249086451 scopus 로고    scopus 로고
    • Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 49-phosphatase activities
    • Coats SR, Jones JW, Do CT, et al. Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 49-phosphatase activities. Cell Microbiol 2009;11:1587-1599.
    • (2009) Cell Microbiol , vol.11 , pp. 1587-1599
    • Coats, S.R.1    Jones, J.W.2    Do, C.T.3
  • 15
    • 0037268875 scopus 로고    scopus 로고
    • Perspective of cytokine regulation for periodontal treatment: Fibroblast biology
    • Takashiba S, Naruishi K, Murayama Y. Perspective of cytokine regulation for periodontal treatment: Fibroblast biology. J Periodontol 2003;74:103-110.
    • (2003) J Periodontol , vol.74 , pp. 103-110
    • Takashiba, S.1    Naruishi, K.2    Murayama, Y.3
  • 16
    • 33846014243 scopus 로고    scopus 로고
    • Differential chemokine response of fibroblast subtypes to complement C1q
    • Verardi S, Page RC, Ammons WF, Bordin S. Differential chemokine response of fibroblast subtypes to complement C1q. J Periodontal Res 2007;42:62-68.
    • (2007) J Periodontal Res , vol.42 , pp. 62-68
    • Verardi, S.1    Page, R.C.2    Ammons, W.F.3    Bordin, S.4
  • 17
    • 33750485771 scopus 로고    scopus 로고
    • Cytokine production in human periodontal ligament cells stimulated with Porphyromonas gingivalis
    • Yamamoto T, Kita M, Oseko F, Nakamura T, Imanishi J, Kanamura N. Cytokine production in human periodontal ligament cells stimulated with Porphyromonas gingivalis. J Periodontal Res 2006;41:554-559.
    • (2006) J Periodontal Res , vol.41 , pp. 554-559
    • Yamamoto, T.1    Kita, M.2    Oseko, F.3    Nakamura, T.4    Imanishi, J.5    Kanamura, N.6
  • 18
    • 0028302285 scopus 로고
    • Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 alpha by inflammatory granuloma fibroblasts
    • Lukacs NW, Chensue SW, Smith RE, et al. Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 alpha by inflammatory granuloma fibroblasts. Am J Pathol 1994;144:711-718.
    • (1994) Am J Pathol , vol.144 , pp. 711-718
    • Lukacs, N.W.1    Chensue, S.W.2    Smith, R.E.3
  • 20
    • 23244435467 scopus 로고    scopus 로고
    • How do stem cells find their way home?
    • Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005;106:1901-1910.
    • (2005) Blood , vol.106 , pp. 1901-1910
    • Lapidot, T.1    Dar, A.2    Kollet, O.3
  • 21
    • 78651362828 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1): Homing factor for engineered regenerative medicine
    • Lau TT, Wang DA. Stromal cell-derived factor-1 (SDF-1): Homing factor for engineered regenerative medicine. Expert Opin Biol Ther 2011;11:189-197.
    • (2011) Expert Opin Biol Ther , vol.11 , pp. 189-197
    • Lau, T.T.1    Wang, D.A.2
  • 22
    • 44349163379 scopus 로고    scopus 로고
    • Stromal-derived factor-1alpha (CXCL12) levels increase in periodontal disease
    • Havens AM, Chiu E, Taba M, et al. Stromal-derived factor-1alpha (CXCL12) levels increase in periodontal disease. J Periodontol 2008;79:845-853.
    • (2008) J Periodontol , vol.79 , pp. 845-853
    • Havens, A.M.1    Chiu, E.2    Taba, M.3
  • 23
    • 18544379954 scopus 로고    scopus 로고
    • Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells
    • Kortesidis A, Zannettino A, Isenmann S, Shi S, Lapidot T, Gronthos S. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood 2005;105: 3793-3801.
    • (2005) Blood , vol.105 , pp. 3793-3801
    • Kortesidis, A.1    Zannettino, A.2    Isenmann, S.3    Shi, S.4    Lapidot, T.5    Gronthos, S.6
  • 24
    • 84857885102 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 significantly induces proliferation, migration, and collagen type i expression in a human periodontal ligament stem cell subpopulation
    • Du L, Yang P, Ge S. Stromal cell-derived factor-1 significantly induces proliferation, migration, and collagen type I expression in a human periodontal ligament stem cell subpopulation. J Periodontol 2012;83: 379-388.
    • (2012) J Periodontol , vol.83 , pp. 379-388
    • Du, L.1    Yang, P.2    Ge, S.3
  • 25
    • 0024421453 scopus 로고
    • Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils
    • Baggiolini M, Walz A, Kunkel SL. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest 1989;84:1045-1049.
    • (1989) J Clin Invest , vol.84 , pp. 1045-1049
    • Baggiolini, M.1    Walz, A.2    Kunkel, S.L.3
  • 26
    • 17644368573 scopus 로고    scopus 로고
    • Interleukin-6: From basic science to medicine - 40 years in immunology
    • Kishimoto T. Interleukin-6: From basic science to medicine - 40 years in immunology. Annu Rev Immunol 2005;23:1-21.
    • (2005) Annu Rev Immunol , vol.23 , pp. 1-21
    • Kishimoto, T.1
  • 28
    • 77649230692 scopus 로고    scopus 로고
    • Differential production of macrophage inflammatory protein- 1alpha, stromal-derived factor-1, and IL-6 by human cultured periodontal ligament and gingival fibroblasts challenged with lipopolysaccharide from P. gingivalis
    • Morandini AC, Sipert CR, Gasparoto TH, et al. Differential production of macrophage inflammatory protein- 1alpha, stromal-derived factor-1, and IL-6 by human cultured periodontal ligament and gingival fibroblasts challenged with lipopolysaccharide from P. gingivalis. J Periodontol 2010;81:310-317.
    • (2010) J Periodontol , vol.81 , pp. 310-317
    • Morandini, A.C.1    Sipert, C.R.2    Gasparoto, T.H.3
  • 29
    • 77955485089 scopus 로고    scopus 로고
    • Stimulation of IL-6 cytokines in fibroblasts by toll-like receptors 2
    • Souza PP, Palmqvist P, Lundgren I, et al. Stimulation of IL-6 cytokines in fibroblasts by toll-like receptors 2. J Dent Res 2010;89:802-807.
    • (2010) J Dent Res , vol.89 , pp. 802-807
    • Souza, P.P.1    Palmqvist, P.2    Lundgren, I.3
  • 30
    • 71049131211 scopus 로고    scopus 로고
    • Heat-killed Enterococcus faecalis alters nitric oxide and CXCL12 production but not CXCL8 and CCL3 production by cultured human dental pulp fibroblasts
    • Sipert CR, Moraes IG, Bernardinelli N, et al. Heat-killed Enterococcus faecalis alters nitric oxide and CXCL12 production but not CXCL8 and CCL3 production by cultured human dental pulp fibroblasts. J Endod 2010; 36:91-94.
    • (2010) J Endod , vol.36 , pp. 91-94
    • Sipert, C.R.1    Moraes, I.G.2    Bernardinelli, N.3
  • 31
    • 79955733267 scopus 로고    scopus 로고
    • Periodontal ligament and gingival fibroblasts participate in the production of TGF-b, interleukin (IL)-8 and IL-10
    • Morandini AC, Sipert CR, Ramos-Junior ES, Brozoski DT, Santos CF. Periodontal ligament and gingival fibroblasts participate in the production of TGF-b, interleukin (IL)-8 and IL-10. Braz Oral Res 2011;25: 157-162.
    • (2011) Braz Oral Res , vol.25 , pp. 157-162
    • Morandini, A.C.1    Sipert, C.R.2    Ramos-Junior, E.S.3    Brozoski, D.T.4    Santos, C.F.5
  • 32
    • 79959609269 scopus 로고    scopus 로고
    • Periodontal ligament and gingival fibroblasts from periodontitis patients are more active in interaction with Porphyromonas gingivalis
    • Scheres N, Laine ML, Sipos PM, et al. Periodontal ligament and gingival fibroblasts from periodontitis patients are more active in interaction with Porphyromonas gingivalis. J Periodontal Res 2011;46:407-416.
    • (2011) J Periodontal Res , vol.46 , pp. 407-416
    • Scheres, N.1    Laine, M.L.2    Sipos, P.M.3
  • 33
    • 0037954568 scopus 로고    scopus 로고
    • Contrasting responses of human gingival and periodontal ligament fibroblasts to bacterial cell-surface components through the CD14/Toll-like receptor system
    • Hatakeyama J, Tamai R, Sugiyama A, Akashi S, Sugawara S, Takada H. Contrasting responses of human gingival and periodontal ligament fibroblasts to bacterial cell-surface components through the CD14/Toll-like receptor system. Oral Microbiol Immunol 2003;18:14-23.
    • (2003) Oral Microbiol Immunol , vol.18 , pp. 14-23
    • Hatakeyama, J.1    Tamai, R.2    Sugiyama, A.3    Akashi, S.4    Sugawara, S.5    Takada, H.6
  • 34
    • 41049098801 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling plays a role in triggering periodontal infection
    • Sun Y, Shu R, Zhang MZ, Wu AP. Toll-like receptor 4 signaling plays a role in triggering periodontal infection. FEMS Immunol Med Microbiol 2008;52:362-369.
    • (2008) FEMS Immunol Med Microbiol , vol.52 , pp. 362-369
    • Sun, Y.1    Shu, R.2    Zhang, M.Z.3    Wu, A.P.4
  • 35
    • 34547218463 scopus 로고    scopus 로고
    • Insights into effective RNAi gained from large-scale siRNA validation screening
    • Krueger U, Bergauer T, Kaufmann B, et al. Insights into effective RNAi gained from large-scale siRNA validation screening. Oligonucleotides 2007;17:237-250.
    • (2007) Oligonucleotides , vol.17 , pp. 237-250
    • Krueger, U.1    Bergauer, T.2    Kaufmann, B.3
  • 36
    • 33846211910 scopus 로고    scopus 로고
    • IL-8 and IDO expression by human gingival fibroblasts via TLRs
    • Mahanonda R, Sa-Ard-Iam N, Montreekachon P, et al. IL-8 and IDO expression by human gingival fibroblasts via TLRs. J Immunol 2007;178:1151-1157.
    • (2007) J Immunol , vol.178 , pp. 1151-1157
    • Mahanonda, R.1    Sa-Ard-Iam, N.2    Montreekachon, P.3
  • 37
    • 33645535833 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: Differential activities of tetra- and penta-acylated lipid A structures on E-selectin expression and TLR4 recognition
    • Reife RA, Coats SR, Al-Qutub M, et al. Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: Differential activities of tetra- and penta-acylated lipid A structures on E-selectin expression and TLR4 recognition. Cell Microbiol 2006;8:857-868.
    • (2006) Cell Microbiol , vol.8 , pp. 857-868
    • Reife, R.A.1    Coats, S.R.2    Al-Qutub, M.3
  • 38
    • 25444528950 scopus 로고    scopus 로고
    • MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex
    • Coats SR, Pham TT, Bainbridge BW, Reife RA, Darveau RP. MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex. J Immunol 2005;175:4490-4498.
    • (2005) J Immunol , vol.175 , pp. 4490-4498
    • Coats, S.R.1    Pham, T.T.2    Bainbridge, B.W.3    Reife, R.A.4    Darveau, R.P.5
  • 39
    • 33746637141 scopus 로고    scopus 로고
    • Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide
    • Al-Qutub MN, Braham PH, Karimi-Naser LM, Liu X, Genco CA, Darveau RP. Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide. Infect Immun 2006;74:4474-4485.
    • (2006) Infect Immun , vol.74 , pp. 4474-4485
    • Al-Qutub, M.N.1    Braham, P.H.2    Karimi-Naser, L.M.3    Liu, X.4    Genco, C.A.5    Darveau, R.P.6
  • 40
    • 78249264730 scopus 로고    scopus 로고
    • Gram-negative periodontal bacteria induce the activation of Toll-like receptors 2 and 4, and cytokine production in human periodontal ligament cells
    • Sun Y, Shu R, Li CL, Zhang MZ. Gram-negative periodontal bacteria induce the activation of Toll-like receptors 2 and 4, and cytokine production in human periodontal ligament cells. J Periodontol 2010;81: 1488-1496.
    • (2010) J Periodontol , vol.81 , pp. 1488-1496
    • Sun, Y.1    Shu, R.2    Li, C.L.3    Zhang, M.Z.4
  • 41
    • 78651105236 scopus 로고    scopus 로고
    • CXCL12 gene expression is upregulated by hypoxia and growth arrest but not by inflammatory cytokines in rheumatoid synovial fibroblasts
    • Santiago B, Calonge E, Del Rey MJ, et al. CXCL12 gene expression is upregulated by hypoxia and growth arrest but not by inflammatory cytokines in rheumatoid synovial fibroblasts. Cytokine 2011;53:184-190.
    • (2011) Cytokine , vol.53 , pp. 184-190
    • Santiago, B.1    Calonge, E.2    Del Rey, M.J.3
  • 42
    • 79960532406 scopus 로고    scopus 로고
    • Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling
    • Delano MJ, Kelly-Scumpia KM, Thayer TC, et al. Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling. J Immunol 2011;187:911-918.
    • (2011) J Immunol , vol.187 , pp. 911-918
    • Delano, M.J.1    Kelly-Scumpia, K.M.2    Thayer, T.C.3
  • 43
    • 79951617630 scopus 로고    scopus 로고
    • LPS promotes pre-osteoclast activity by up-regulating CXCR4 via TLR-4
    • Xing Q, de Vos P, Faas MM, Ye Q, Ren Y. LPS promotes pre-osteoclast activity by up-regulating CXCR4 via TLR-4. J Dent Res 2011;90:157-162.
    • (2011) J Dent Res , vol.90 , pp. 157-162
    • Xing, Q.1    De Vos, P.2    Faas, M.M.3    Ye, Q.4    Ren, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.