Heat-killed Enterococcus faecalis Alters Nitric Oxide and CXCL12 Production but not CXCL8 and CCL3 Production by Cultured Human Dental Pulp Fibroblasts

Journal of Endodontics

Volumn 36, Issue 1, 2010, Pages 91-94

  Sipert, Carla R ^a   Moraes, Ivaldo G ^a   Bernardinelli, Norberti ^a   Garcia, Roberto B ^a   Bramante, Clóvis M ^a   Gasparoto, Thaís H ^a   Figueira, Eduardo A ^a   Dionísio, Thiago J ^a   Campanelli, Ana P ^a   Oliveira, Sandra H P ^b   Cunha, Fernando Q ^a   Santos, Carlos F ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

CCL3; chemokines; CXCL12; CXCL8; dental pulp fibroblasts; Enterococcus faecalis; innate immunity; nitric oxide; pulpitis

Indexed keywords

CCL3 PROTEIN, HUMAN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; NITRIC OXIDE; STROMAL CELL DERIVED FACTOR 1; VIRULENCE FACTOR;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL PROLIFERATION; CELL WALL; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; ENTEROCOCCUS FAECALIS; FIBROBLAST; HEAT; HUMAN; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; TOOTH PULP; UPREGULATION;

CELL PROLIFERATION; CELL WALL; CELLS, CULTURED; CHEMOKINE CCL3; CHEMOKINE CXCL12; CULTURE MEDIA, CONDITIONED; DENTAL PULP; ENTEROCOCCUS FAECALIS; FIBROBLASTS; HOT TEMPERATURE; HUMANS; INTERLEUKIN-8; NITRIC OXIDE; UP-REGULATION; VIRULENCE FACTORS;

EID: 71049131211     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2009.10.014     Document Type: Article

References (42)

1. Chiego Jr. D. Histology of the pulp. In: Avery J. (Ed). Oral development and histology. 3rd ed (2002), Georg Thieme Verlag, Stuttgart 190-212
2. Kokkas A.B., Goulas A., Varsamidis K., Mirtsou V., and Tziafas D. Irreversible but not reversible pulpitis is associated with up-regulation of tumour necrosis factor-alpha gene expression in human pulp. Int Endod J 40 (2007) 198-203
3. Yang L.C., Huang F.M., Lin C.S., Liu C.M., Lai C.C., and Chang Y.C. Induction of interleukin-8 gene expression by black-pigmented Bacteroides in human pulp fibroblasts and osteoblasts. Int Endod J 36 (2003) 774-779
4. Yang L.C., Tsai C.H., Huang F.M., et al. Induction of vascular endothelial growth factor expression in human pulp fibroblasts stimulated with black-pigmented Bacteroides. Int Endod J 37 (2004) 588-592
5. Baggiolini M., Dewald B., and Moser B. Human chemokines: an update. Annu Rev Immunol 15 (1997) 675-705
6. Hahn C.L., and Liewehr F.R. Innate immune responses of the dental pulp to caries. J Endod 33 (2007) 643-651
7. Maurer M., and von Stebut E. Macrophage inflammatory protein-1. Int J Biochem Cell Biol 36 (2004) 1882-1886
8. Hirafuji M., Satoh S., and Ogura Y. Prostaglandins in rat pulp tissue. J Dent Res 59 (1980) 1535-1540
9. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 6 (1992) 3051-3064
10. Nussler A.K., and Billiar T.R. Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukoc Biol 54 (1993) 171-178
11. Okiji T. Pulp as a connective tissue. In: Hargreaves K., and Goodis H. (Eds). Seltzer and Bender's dental pulp (2002), Quintessence Publishing Co, Carol Stream, IL 95-122
12. Hosokawa Y., Hosokawa I., Ozaki K., et al. CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease. Clin Exp Immunol 141 (2005) 467-474
13. Ogura N., Tobe M., Sakamaki H., Nagura H., Abiko Y., and Kondoh T. Tumor necrosis factor-alpha increases chemokine gene expression and production in synovial fibroblasts from human temporomandibular joint. J Oral Pathol Med 34 (2005) 357-363
14. Sismey-Durrant H.J., and Hopps R.M. Effect of lipopolysaccharide from Porphyromonas gingivalis on prostaglandin E2 and interleukin-1-beta release from rat periosteal and human gingival fibroblasts in vitro. Oral Microbiol Immunol 6 (1991) 378-380
15. Uehara A., and Takada H. Functional TLRs and NODs in human gingival fibroblasts. J Dent Res 86 (2007) 249-254
16. Wang P.L., Azuma Y., Shinohara M., and Ohura K. Toll-like receptor 4-mediated signal pathway induced by Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts. Biochem Biophys Res Commun 273 (2000) 1161-1167
17. Gutierrez-Venegas G., Maldonado-Frias S., Ontiveros-Granados A., and Kawasaki-Cardenas P. Role of p38 in nitric oxide synthase and cyclooxygenase expression, and nitric oxide and PGE2 synthesis in human gingival fibroblasts stimulated with lipopolysaccharides. Life Sci 77 (2005) 60-73
18. Brouty-Boye D., Pottin-Clemenceau C., Doucet C., Jasmin C., and Azzarone B. Chemokines and CD40 expression in human fibroblasts. Eur J Immunol 30 (2000) 914-919
19. Hatakeyama J., Tamai R., Sugiyama A., Akashi S., Sugawara S., and Takada H. Contrasting responses of human gingival and periodontal ligament fibroblasts to bacterial cell-surface components through the CD14/Toll-like receptor system. Oral Microbiol Immunol 18 (2003) 14-23
20. Sedgley C., Buck G., and Appelbe O. Prevalence of Enterococcus faecalis at multiple oral sites in endodontic patients using culture and PCR. J Endod 32 (2006) 104-109
21. Williams J.M., Trope M., Caplan D.J., and Shugars D.C. Detection and quantitation of E. faecalis by real-time PCR (qPCR), reverse transcription-PCR (RT-PCR), and cultivation during endodontic treatment. J Endod 32 (2006) 715-721
22. Spangberg L.S. Infatuated by Enterococci. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102 (2006) 577-578
23. Reusch Jr. V.M. Lipopolymers, isoprenoids, and the assembly of the gram-positive cell wall. Crit Rev Microbiol 11 (1984) 129-155
24. Noel Jr. R.F., Sato T.T., Mendez C., Johnson M.C., and Pohlman T.H. Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14. Infect Immun 63 (1995) 4046-4053
25. Gasparoto T.H., Vieira N.A., Porto V.C., Campanelli A.P., and Lara V.S. Ageing exacerbates damage of systemic and salivary neutrophils from patients presenting Candida-related denture stomatitis. Immun Ageing 6 (2009) 3
26. Stuehr D.J., and Nathan C.F. Nitric oxide: a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp Med 169 (1989) 1543-1555
27. Strauss L., Bergmann C., and Whiteside T.L. Human circulating CD4 + CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis. J Immunol 182 (2009) 1469-1480
28. Bradfield P.F., Amft N., Vernon-Wilson E., et al. Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4+ and CD8 + T cell migration within synovial tissue. Arthritis Rheum 48 (2003) 2472-2482
29. Mahanonda R., Sa-Ard-Iam N., Montreekachon P., et al. IL-8 and IDO expression by human gingival fibroblasts via TLRs. J Immunol 178 (2007) 1151-1157
30. Botero J.E., Contreras A., and Parra B. Profiling of inflammatory cytokines produced by gingival fibroblasts after human cytomegalovirus infection. Oral Microbiol Immunol 23 (2008) 291-298
31. Huang G.T., Lee H.W., Lee H.S., et al. Localization of substance P-induced upregulated interleukin-8 expression in human dental pulp explants. Int Endod J 41 (2008) 100-107
32. Paakkonen V., Vuoristo J., Salo T., and Tjaderhane L. Effects of TGF-beta 1 on interleukin profile of human dental pulp and odontoblasts. Cytokine 40 (2007) 44-51
33. Chang M.C., Chang H.H., Lee M.Y., et al. Prostaglandin F(2alpha)-induced interleukin-8 production in human dental pulp cells is associated with MEK/ERK signaling. J Endod 35 (2009) 508-512
34. Thaweboon B., Thaweboon S., Choonharuangdej S., and Suppakpatana P. Effects of sonicated Prevotella intermedia, Fusobacterium nucleatum and Lactobacillus casei extracts on interleukin-8 production by human dental pulp cells. Southeast Asian J Trop Med Public Health 37 (2006) 523-527
35. Jiang H.W., Ling J.Q., and Gong Q.M. The expression of stromal cell-derived factor 1 (SDF-1) in inflamed human dental pulp. J Endod 34 (2008) 1351-1354
36. Jiang L., Zhu Y.Q., Du R., et al. The expression and role of stromal cell-derived factor-1alpha-CXCR4 axis in human dental pulp. J Endod 34 (2008) 939-944
37. Farges J.C., Keller J.F., Carrouel F., et al. Odontoblasts in the dental pulp immune response. J Exp Zool B Mol Dev Evol (2009) Jul 15;312B(5):425-36
38. Di Nardo Di Maio F., Lohinai Z., D'Arcangelo C., et al. Nitric oxide synthase in healthy and inflamed human dental pulp. J Dent Res 83 (2004) 312-316
39. Yasuhara R., Suzawa T., Miyamoto Y., et al. Nitric oxide in pulp cell growth, differentiation, and mineralization. J Dent Res 86 (2007) 163-168
40. Nishikawa T, E Fs, Choudhury T, et al. Effect of nitric oxide on the oxygen metabolism and growth of E. faecalis. J Clin Biochem Nutr 2009;44:178-184.
41. Shockman G.D., and Barrett J.F. Structure, function, and assembly of cell walls of gram-positive bacteria. Annu Rev Microbiol 37 (1983) 501-527
42. Signoretto C., Lleo M.M., Tafi M.C., and Canepari P. Cell wall chemical composition of Enterococcus faecalis in the viable but nonculturable state. Appl Environ Microbiol 66 (2000) 1953-1959