-
2
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
DOI 10.1007/s00401-007-0243-4
-
D.N. Louis, H. Ohgaki, O.D. Wiestler, and W.K. Cavenee The 2007 WHO classification of tumours of the central nervous system Acta Neuropathol 114 2007 97 109 (Pubitemid 47103521)
-
(2007)
Acta Neuropathologica
, vol.114
, Issue.2
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
Kleihues, P.8
-
4
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
R. Stupp, W.P. Mason, and M. Van den Bent Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996 (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
5
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
DOI 10.1056/NEJMoa051918
-
I.K. Mellinghoff, M.Y. Wang, and Y. Vivanco Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors N Engl J Med 2005 353 2005 2012 2024 (Pubitemid 41609094)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
Haas-Kogan, D.A.4
Zhu, S.5
Dia, E.Q.6
Lu, K.V.7
Yoshimoto, K.8
Huang, J.H.Y.9
Chute, D.J.10
Riggs, B.L.11
Horvath, S.12
Liau, L.M.13
Cavenee, W.K.14
Nagesh Rao, P.15
Beroukhim, R.16
Peck, T.C.17
Lee, J.C.18
Sellers, W.R.19
Stokoe, D.20
Prados, M.21
Cloughesy, T.F.22
Sawyers, C.L.23
Mischel, P.S.24
more..
-
6
-
-
48749130017
-
Epithelial growth factor receptor inhibitors for treatment of recurrent or progressive high grade glioma: An exploratory study
-
M. Preusser, E. Gelpi, and A. Rottenfusser Epithelial growth factor receptor inhibitors for treatment of recurrent or progressive high grade glioma: an exploratory study J Neurooncol 89 2008 211 218
-
(2008)
J Neurooncol
, vol.89
, pp. 211-218
-
-
Preusser, M.1
Gelpi, E.2
Rottenfusser, A.3
-
7
-
-
27744439793
-
Glioblastoma multiforme and the epidermal growth factor receptor
-
DOI 10.1056/NEJMp058186
-
H.S. Friedman, and D.D. Bigner Glioblastoma multiforme and the epidermal growth factor receptor N Engl J Med 353 2005 1997 1999 (Pubitemid 41609092)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.19
, pp. 1997-1999
-
-
Friedman, H.S.1
Bigner, D.D.2
-
8
-
-
67651154339
-
Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: Where we do stand?
-
G. Karpel-Massler, U. Schmidt, and A. Unterberg Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: where we do stand? Mol Cancer Res 7 2009 1000 1012
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1000-1012
-
-
Karpel-Massler, G.1
Schmidt, U.2
Unterberg, A.3
-
9
-
-
57149118473
-
Phase I/II Trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed Glioblastoma Multiforme: North Central Cancer Treatment Group Study N0177
-
P.D. Brown, S. Krishnan, and J.N. Sarkaria Phase I/II Trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed Glioblastoma Multiforme: North Central Cancer Treatment Group Study N0177 J Clin Oncol 26 2008 5603 5609
-
(2008)
J Clin Oncol
, vol.26
, pp. 5603-5609
-
-
Brown, P.D.1
Krishnan, S.2
Sarkaria, J.N.3
-
10
-
-
75749110539
-
A phase i trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas
-
J.J. Raizer, L.E. Abrey, and A.B. Lassman A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas Neuro Oncol 12 2010 87 94
-
(2010)
Neuro Oncol
, vol.12
, pp. 87-94
-
-
Raizer, J.J.1
Abrey, L.E.2
Lassman, A.B.3
-
11
-
-
75749122223
-
A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy
-
J.J. Raizer, L.E. Abrey, and A.B. Lassman A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy Neuro Oncol 12 2010 95 103
-
(2010)
Neuro Oncol
, vol.12
, pp. 95-103
-
-
Raizer, J.J.1
Abrey, L.E.2
Lassman, A.B.3
-
12
-
-
75049084471
-
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
-
D.A. Reardon, A. Desjardins, and J.J. Vredenburgh Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma Clin Cancer Res 96 2006 219 230
-
(2006)
Clin Cancer Res
, vol.96
, pp. 219-230
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
-
13
-
-
12344334489
-
DNMAD: Web-based diagnosis and normalization for microarray data
-
DOI 10.1093/bioinformatics/bth401
-
J.M. Vaquerizas, J. Dopazo, and R. Diaz-Uriarte DNMAD: web-based diagnosis and normalization for microarray data Bioinformatics 20 2004 3656 3658 (Pubitemid 40136807)
-
(2004)
Bioinformatics
, vol.20
, Issue.18
, pp. 3656-3658
-
-
Vaquerizas, J.M.1
Dopazo, J.2
Diaz-Uriarte, R.3
-
14
-
-
74849135994
-
Gene expression pathway analysis to predict response to neoadjuvant docetaxel and capecitabine for breast cancer
-
L.A. Korde, L. Lusa, and L. McShane Gene expression pathway analysis to predict response to neoadjuvant docetaxel and capecitabine for breast cancer Breast Cancer Res Treat 119 2010 685 699
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 685-699
-
-
Korde, L.A.1
Lusa, L.2
McShane, L.3
-
15
-
-
0038005018
-
DAVID: Database for Annotation, Visualization, and Integrated Discovery
-
G. Dennis, B.T. Sherman, and D.A. Hosack DAVID: Database for Annotation, Visualization, and Integrated Discovery Genome Biol 4 2003 P3
-
(2003)
Genome Biol
, vol.4
, pp. 3
-
-
Dennis, G.1
Sherman, B.T.2
Hosack, D.A.3
-
16
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
W. Huang, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat Protoc 4 2009 44 57
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
17
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
DOI 10.1073/pnas.0506580102
-
A. Subramanian, P. Tamayo, and V.K. Mootha Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc Natl Acad Sci USA 102 2005 15545 15550 (Pubitemid 41528093)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
18
-
-
68849091778
-
NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas
-
T.J. Liu, D. Koul, and T. LaFortune NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas Mol Cancer Ther 8 2009 2204 2210
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2204-2210
-
-
Liu, T.J.1
Koul, D.2
Lafortune, T.3
-
19
-
-
35648949422
-
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
-
DOI 10.1371/journal.pmed.0040315
-
D.B. Costa, B.H. Halmos, and A. Kumar BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancer with oncogenic EGFR mutations PLoS Med 4 2007 1669 1680 (Pubitemid 350035456)
-
(2007)
PLoS Medicine
, vol.4
, Issue.10
, pp. 1669-1680
-
-
Costa, D.B.1
Halmos, B.2
Kumar, A.3
Schumer, S.T.4
Huberman, M.S.5
Boggon, T.J.6
Tenen, D.G.7
Kobayashi, S.8
-
20
-
-
35648965243
-
Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas
-
DOI 10.1371/journal.pmed.0040294
-
Y. Gong, R. Sonwar, and K. Politi Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas PLoS Med 4 2007 1655 1668 (Pubitemid 350035455)
-
(2007)
PLoS Medicine
, vol.4
, Issue.10
, pp. 1655-1668
-
-
Gong, Y.1
Somwar, R.2
Politi, K.3
Balak, M.4
Chmielecki, J.5
Jiang, X.6
Pao, W.7
-
21
-
-
33746928318
-
Complex mutation patterns of epidermal growth factor receptor gene associated with variable responses to gefitinib treatment in patients with non-small cell lung cancer
-
M.H. Hsieh, Y.F. Fang, and W.C. Chang Complex mutation patterns of epidermal growth factor receptor gene associated with variable responses to gefitinib treatment in patients with non-small cell lung cancer Lung Cancer 53 2006 311 322
-
(2006)
Lung Cancer
, vol.53
, pp. 311-322
-
-
Hsieh, M.H.1
Fang, Y.F.2
Chang, W.C.3
-
22
-
-
33845926387
-
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain
-
DOI 10.1371/journal.pmed.0030485
-
J. Lee, I. Vivanco, and R. Beroukhim Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain PLoS Med 3 2006 2264 2273 (Pubitemid 46028511)
-
(2006)
PLoS Medicine
, vol.3
, Issue.12
, pp. 2264-2273
-
-
Lee, J.C.1
Vivanco, I.2
Beroukhim, R.3
Huang, J.H.Y.4
Feng, W.L.5
DeBiasi, R.M.6
Yoshimoto, K.7
King, J.C.8
Nghiemphu, P.9
Yuza, Y.10
Xu, Q.11
Greulich, H.12
Thomas, R.K.13
Paez, J.G.14
Peck, T.C.15
Linhart, D.J.16
Glatt, K.A.17
Getz, G.18
Onofrio, R.19
Ziaugra, L.20
Levine, R.L.21
Gabriel, S.22
Kawaguchi, T.23
O'Neill, K.24
Khan, H.25
Liau, L.M.26
Nelson, S.F.27
Rao, P.N.28
Mischel, P.29
Pieper, R.O.30
Cloughesy, T.31
Leahy, D.J.32
Sellers, W.R.33
Sawyers, C.L.34
Meyerson, M.35
Mellinghoff, I.K.36
more..
-
23
-
-
33748058820
-
Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells
-
DOI 10.1158/0008-5472.CAN-04-4392
-
M.Y. Wang, K.V. Lu, and S. Zhu Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells Cancer Res 66 2006 7864 7869 (Pubitemid 44299148)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 7864-7869
-
-
Wang, M.Y.1
Lu, K.V.2
Zhu, S.3
Dia, E.Q.4
Vivanco, I.5
Shackleford, G.M.6
Cavenee, W.K.7
Mellinghoff, I.K.8
Cloughesy, T.F.9
Sawyers, C.L.10
Mischel, P.S.11
-
24
-
-
72049101446
-
Molecularly targeted therapies for malignant glioma: Rationale for combinatorial strategies
-
N.G. Thaker, and I.F. Pollack Molecularly targeted therapies for malignant glioma: rationale for combinatorial strategies Expert Rev Neurother 9 2009 1815 1836
-
(2009)
Expert Rev Neurother
, vol.9
, pp. 1815-1836
-
-
Thaker, N.G.1
Pollack, I.F.2
-
25
-
-
33644836724
-
Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours
-
DOI 10.1016/j.ctrv.2006.01.003, PII S0305737206000090
-
M.E. Halatsch, U. Schmidt, and J. Behnke-Mursch Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours Cancer Treat Rev 32 2006 74 89 (Pubitemid 43362229)
-
(2006)
Cancer Treatment Reviews
, vol.32
, Issue.2
, pp. 74-89
-
-
Halatsch, M.-E.1
Schmidt, U.2
Behnke-Mursch, J.3
Unterberg, A.4
Wirtz, C.R.5
-
26
-
-
58149145875
-
Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib
-
M.E. Halatsch, S. Löw, and T. Hielsher Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib Anticancer Res 28 2008 3725 3728
-
(2008)
Anticancer Res
, vol.28
, pp. 3725-3728
-
-
Halatsch, M.E.1
Löw, S.2
Hielsher, T.3
-
27
-
-
68849121642
-
Candidate genes for sensitivity and resistance of human glioblastoma multiforme cell lines to erlotinib
-
M.E. Halatsch, S. Löw, and K. Mursch Candidate genes for sensitivity and resistance of human glioblastoma multiforme cell lines to erlotinib J Neurosurg 111 2009 211 218
-
(2009)
J Neurosurg
, vol.111
, pp. 211-218
-
-
Halatsch, M.E.1
Löw, S.2
Mursch, K.3
-
28
-
-
33847647117
-
Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
-
DOI 10.1073/pnas.0611271104
-
L. Soroceanu, S. Kharbanda, and R. Chen Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma Proc Natl Acad Sci USA 104 2007 3466 3471 (Pubitemid 46364182)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3466-3471
-
-
Soroceanu, L.1
Kharbanda, S.2
Chen, R.3
Soriano, R.H.4
Aldape, K.5
Misra, A.6
Zha, J.7
Forrest, W.F.8
Nigro, J.M.9
Modrusan, Z.10
Feuerstein, B.G.11
Phillips, H.S.12
-
29
-
-
34848891922
-
Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer
-
DOI 10.1158/1078-0432.CCR-06-2660
-
L. Zhang, J. Huang, and N. Yang Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer Clin Cancer Res 13 2007 5314 5321 (Pubitemid 47510355)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.18
, pp. 5314-5321
-
-
Zhang, L.1
Huang, J.2
Yang, N.3
Greshock, J.4
Liang, S.5
Hasegawa, K.6
Giannakakis, A.7
Poulos, N.8
O'Brien-Jenkins, A.9
Katsaros, D.10
Butzow, R.11
Weber, B.L.12
Coukos, G.13
-
30
-
-
41649086716
-
E2F1 in gliomas: A paradigm of oncogene addiction
-
M.M. Alonso, R. Alemany, and J. Fueyo E2F1 in gliomas: a paradigm of oncogene addiction Cancer Lett 263 2008 157 163
-
(2008)
Cancer Lett
, vol.263
, pp. 157-163
-
-
Alonso, M.M.1
Alemany, R.2
Fueyo, J.3
-
31
-
-
33745472798
-
E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to ras inhibition
-
DOI 10.1002/ijc.21735
-
R. Blum, I. Nakdimon, and L. Goldberg E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition Int J Cancer 119 2006 527 538 (Pubitemid 43955705)
-
(2006)
International Journal of Cancer
, vol.119
, Issue.3
, pp. 527-538
-
-
Blum, R.1
Nakdimon, I.2
Goldberg, L.3
Elkon, R.4
Shamir, R.5
Rechavi, G.6
Kloog, Y.7
-
32
-
-
77954341696
-
Survival signalling and apoptosis resistance in glioblastomas: Opportunities for targeted therapeutics
-
C. Krakstad, and M. Chekenya Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics Mol Cancer 9 2010 135 149
-
(2010)
Mol Cancer
, vol.9
, pp. 135-149
-
-
Krakstad, C.1
Chekenya, M.2
-
33
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
B.T. Hennessy, D.L. Smith, and P.T. Ram Exploiting the PI3K/AKT pathway for cancer drug discovery Nat Rev Drug Discov 4 2005 988 1004
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
-
34
-
-
79957926581
-
Targeting Ras-RAF-ERK and its interactive pathways as a novel therapy for malignant gliomas
-
H.W. Lo Targeting Ras-RAF-ERK and its interactive pathways as a novel therapy for malignant gliomas Curr Cancer Drug Targets 10 2010 840 848
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 840-848
-
-
Lo, H.W.1
-
35
-
-
66349086978
-
Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation
-
S. Paternot, and P.P. Roger Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation Cancer Res 69 2009 4577 4581
-
(2009)
Cancer Res
, vol.69
, pp. 4577-4581
-
-
Paternot, S.1
Roger, P.P.2
-
36
-
-
78649831949
-
Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells
-
J. Sunayama, K. Matsuda, and A. Sato Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells Stem Cells 28 2010 1930 1939
-
(2010)
Stem Cells
, vol.28
, pp. 1930-1939
-
-
Sunayama, J.1
Matsuda, K.2
Sato, A.3
-
37
-
-
79953184710
-
A critical role for non-coding RNA GAS5 in growth arrest and rapamycin inhibition in human T-lymphocytes
-
G.T. Williams, M. Mourtada-Maarabouni, and F. Farzaneh A critical role for non-coding RNA GAS5 in growth arrest and rapamycin inhibition in human T-lymphocytes Biochem Soc Trans 39 2011 482 486
-
(2011)
Biochem Soc Trans
, vol.39
, pp. 482-486
-
-
Williams, G.T.1
Mourtada-Maarabouni, M.2
Farzaneh, F.3
-
38
-
-
77951638287
-
Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor
-
T. Kino, D.E. Hurt, and T. Ichijo Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor Sci Signal 3 2010 ra08
-
(2010)
Sci Signal
, vol.3
, pp. 08
-
-
Kino, T.1
Hurt, D.E.2
Ichijo, T.3
|