Mast cells: A pivotal role in pulmonary fibrosis

DNA and Cell Biology

Volumn 32, Issue 4, 2013, Pages 206-218

  Veerappan, Arul ^a   O'Connor, Nathan J ^a   Brazin, Jacqueline ^a   Reid, Alicia C ^a   Jung, Albert ^a   McGee, David ^a   Summers, Barbara ^a   Branch Elliman, Dascher ^a   Stiles, Brendon ^a   Worgall, Stefan ^a   Kaner, Robert J ^a   Silver, Randi B ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; BLEOMYCIN; COLLAGEN; HISTAMINE; HISTAMINE H1 RECEPTOR; RENIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; LUNG FIBROSIS; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS;

ANGIOTENSIN II; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; BLOTTING, WESTERN; CELL PROLIFERATION; COLLAGEN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; HISTAMINE; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG; MALE; MAST CELLS; MICE; MICE, KNOCKOUT; PULMONARY FIBROSIS; RADIOIMMUNOASSAY; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN; TRANSFORMING GROWTH FACTOR BETA1;

MUS; RATTUS;

EID: 84876111030     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2013.2005     Document Type: Article

References (46)

1. Beaulieu, P.L., Gillard, J., Bailey, M., Beaulieu, C., Duceppe, J.S., Lavallee, P., and Wernic, D. (1999). Practical synthesis of BILA 2157 BS, a potent and orally active renin inhibitor: use of an enzyme-catalyzed hydrolysis for the preparation of homochiral succinic acid derivatives. J Org Chem 64, 6622-6634.
2. Bergstresser, P.R., Tigelaar, R.E., and Tharp, M.D. (1984). Conjugated avidin identifies cutaneous rodent and human mast cells. J Invest Dermatol 83, 214-218.
3. Bonniaud, P., Margetts, P.J., Ask, K., Flanders, K., Gauldie, J., and Kolb, M. (2005). TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis. J Immunol 175, 5390-5395.
4. Cairns, J.A., and Walls, A.F. (1997). Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J Clin Invest 99, 1313-1321.
5. Casale, T.B., Trapp, S., Zehr, B., and Hunninghake, G.W. (1988). Bronchoalveolar lavage fluid histamine levels in interstitial lung diseases. Am Rev Respir Dis 138, 1604-1608.
6. Chan, C.Y., St John, A.L., and Abraham, S.N. (2012). Plasticity in mast cell responses during bacterial infections. Curr Opin Microbiol 15, 78-84.
7. Crouch, E. (1990). Pathobiology of pulmonary fibrosis. Am J Physiol 259, L159-L184.
8. Dempsey, O.J. (2006). Clinical review: idiopathic pulmonary fibrosis -past, present and future. Respir Med 100, 1871-1885.
9. Ding, B.S., Nolan, D.J., Guo, P., Babazadeh, A.O., Cao, Z., Rosenwaks, Z., Crystal, R.G., Simons, M., Sato, T.N., Worgall, S., et al. (2011). Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147, 539-553.
10. Galli, S.J., Kalesnikoff, J., Grimbaldeston, M.A., Piliponsky, A.M., Williams, C.M., and Tsai, M. (2005). Mast cells as "tunable" effector and immunoregulatory cells: recent advances. Annu Rev Immunol 23, 749-786.
11. Galli, S.J., and Kitamura, Y. (1987). Genetically mast-cell-deficient W/Wv and Sl/Sldmice. Their value for the analysis of the roles of mast cells in biologic responses in vivo. Am J Pathol 127, 191-198.
12. Goto, T., Befus, D., Low, R., and Bienenstock, J. (1984). Mast cell heterogeneity and hyperplasia in bleomycin-induced pulmonary fibrosis of rats. Am Rev Respir Dis 130, 797-802.
13. Haslam, P.L., Cromwell, O., Dewar, A., and Turner-Warwick, M. (1981). Evidence of increased histamine levels of lung lavage fluids from patients with cryptogenic fibrosing alveolitis. Clin Exp Immunol 44, 587-593.
14. Ibels, L.S., and Gyory, A.Z. (1994). IgA nephropathy: analysis of the natural history, important factors in the progression of renal disease, and a review of the literature. Medicine (Baltimore) 73, 79-102.
15. Izbicki, G., Segel, M.J., Christensen, T.G., Conner, M.W., and Breuer, R. (2002). Time course of bleomycin-induced lung fibrosis. Int J Exp Pathol 83, 111-119.
16. Jordana, M., Befus, A.D., Newhouse, M.T., Bienenstock, J., and Gauldie, J. (1988). Effect of histamine on proliferation of normal human adult lung fibroblasts. Thorax 43, 552-558.
17. Kaner, R.J., Santiago, F., and Crystal, R.G. (2009). Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1 (+) smokers with early emphysema. J Leukoc Biol 86, 913-922.
18. Kawanami, O., Ferrans, V.J., Fulmer, J.D., and Crystal, R.G. (1979). Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders. Lab Invest 40, 717-734.
19. King, T.E., Jr., Pardo, A., and Selman, M. (2011). Idiopathic pulmonary fibrosis. Lancet 378, 1949-1961.
20. Kitamura, Y., Go, S., and Hatanaka, K. (1978). Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation. Blood 52, 447-452.
21. Leslie, M. (2007). Mast cells show their might. Science 317, 614-616.
22. Li, X., Rayford, H., and Uhal, B.D. (2003a). Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice. Am J Pathol 163, 2523-2530.
23. Li, X., Zhang, H., Soledad-Conrad, V., Zhuang, J., and Uhal, B.D. (2003b). Bleomycin-induced apoptosis of alveolar epithelial cells requires angiotensin synthesis de novo. Am J Physiol Lung Cell Mol Physiol 284, L501-L507.
24. Marshall, R.P., McAnulty, R.J., and Laurent, G.J. (2000). Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor. Am J Respir Crit Care Med 161, 1999-2004.
25. Martin, M.M., Buckenberger, J.A., Jiang, J., Malana, G.E., Knoell, D.L., Feldman, D.S., and Elton, T.S. (2007). TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways. Am J Physiol Lung Cell Mol Physiol 293, L790-799.
26. Meltzer, E.B., and Noble, P.W. (2008). Idiopathic pulmonary fibrosis. Orphanet J Rare Dis 3, 8.
27. Metcalfe, D.D., Baram, D., and Mekori, Y.A. (1997). Mast cells. Physiol Rev 77, 1033-1079.
28. Moore, B.B., and Hogaboam, C.M. (2008). Murine models of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 294, L152-L160.
29. Mori, H., Kawada, K., Zhang, P., Uesugi, Y., Sakamoto, O., and Koda, A. (1991). Bleomycin-induced pulmonary fibrosis in genetically mast cell-deficient WBB6F1-W/Wv mice and mechanism of the suppressive effect of tranilast, an antiallergic drug inhibiting mediator release from mast cells, on fibrosis. Int Arch Allergy Appl Immunol 95, 195-201.
30. Noble, P.W., Albera, C., Bradford, W.Z., Costabel, U., Glassberg, M.K., Kardatzke, D., King, T.E., Jr., Lancaster, L., Sahn, S.A., Szwarcberg, J., et al. (2011). Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 377, 1760-1769.
31. Okazaki, T., Hirota, S., Xu, Z.D., Maeyama, K., Nakama, A., Kawano, S., Hori, M., and Kitamura, Y. (1998). Increase of mast cells in the liver and lung may be associated with but not a cause of fibrosis: demonstration using mast cell-deficient Ws/Ws rats. Lab Invest 78, 1431-1438.
32. Otsuka, M., Takahashi, H., Shiratori, M., Chiba, H., and Abe, S. (2004). Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist. Thorax 59, 31-38.
33. Raghu, G., Collard, H.R., Egan, J.J., Martinez, F.J., Behr, J., Brown, K.K., Colby, T.V., Cordier, J.F., Flaherty, K.R., Lasky, J.A., et al. (2011). An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 183, 788-824.
34. Reynolds, H.Y., Fulmer, J.D., Kazmierowski, J.A., Roberts, W.C., Frank, M.M., and Crystal, R.G. (1977). Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. J Clin Invest 59, 165-175.
35. Silver, R.B., Reid, A.C., Mackins, C.J., Askwith, T., Schaefer, U., Herzlinger, D., and Levi, R. (2004). Mast cells: a unique source of renin. Proc Natl Acad Sci U S A 101, 13607-13612.
36. Stramer, B.M., Mori, R., and Martin, P. (2007). The inflammationfibrosis link? A Jekyll and Hyde role for blood cells during wound repair. J Invest Dermatol 127, 1009-1017.
37. Thannickal, V.J., Toews, G.B., White, E.S., Lynch, J.P., 3rd, and Martinez, F.J. (2004). Mechanisms of pulmonary fibrosis. Annu Rev Med 55, 395-417.
38. Tharp, M.D., Seelig, L.L., Jr., Tigelaar, R.E., and Bergstresser, P.R. (1985). Conjugated avidin binds to mast cell granules. J Histochem Cytochem 33, 27-32.
39. Tuder, R.M. (1996). A pathologist's approach to interstitial lung disease. Curr Opin Pulm Med 2, 357-363.
40. Urata, H., Kinoshita, A., Misono, K.S., Bumpus, F.M., and Husain, A. (1990). Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart. J Biol Chem 265, 22348-22357.
41. Veerappan, A., Reid, A.C., Estephan, R., O'Connor, N., Thadani-Mulero, M., Salazar-Rodriguez, M., Levi, R., and Silver, R.B. (2008). Mast cell renin and a local renin-angiotensin system in the airway: role in bronchoconstriction. Proc Natl Acad Sci U S A 105, 1315-1320.
42. Veerappan, A., Reid, A.C., O'Connor, N., Mora, R., Brazin, J.A., Estephan, R., Kameue, T., Chen, J., Felsen, D., Seshan, S.V., et al. (2011). Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model. Am J Physiol Renal Physiol 302, F192-F204.
43. Walls, A.F., Bennett, A.R., Godfrey, R.C., Holgate, S.T., and Church, M.K. (1991). Mast cell tryptase and histamine concentrations in bronchoalveolar lavage fluid from patients with interstitial lung disease. Clin Sci (Lond) 81, 183-188.
44. White, E.S., Lazar, M.H., and Thannickal, V.J. (2003). Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. J Pathol 201, 343-354.
45. Wong, P.C., Price, W.A., Jr., Chiu, A.T., Duncia, J.V., Carini, D.J., Wexler, R.R., Johnson, A.L., and Timmermans, P.B. (1990). Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an activemetabolite ofDuP 753, an orally active antihypertensive agent. J Pharmacol Exp Ther 255, 211-217.
46. Worgall, S., Singh, R., Leopold, P.L., Kaner, R.J., Hackett, N.R., Topf, N., Moore, M.A., and Crystal, R.G. (1999). Selective expansion of alveolar macrophages in vivo by adenovirusmediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA. Blood 93, 655-666.