The efficacy of nuclease-resistant Chol-siRNA in primary breast tumors following complexation with PLL-PEG(5K)

Biomaterials

Volumn 34, Issue 20, 2013, Pages 4839-4848

  Ambardekar, Vishakha V ^a   Wakaskar, Rajesh R ^a   Sharma, Bhawna ^b   Bowman, Joy ^c   Vayaboury, Willy ^c   Singh, Rakesh K ^a,b   Vetro, Joseph A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c Alamanda Polymers   (United States)

Author keywords

Drug delivery; Polymer siRNA complexes; RNA interference; RNAi; SiRNA delivery; SiRNA polyplexes

Indexed keywords

ADVERSE EFFECT; BLOCK LENGTHS; EPITHELIAL CELLS; POLYPLEXES; RNA INTERFERENCE; RNAI; SIRNA DELIVERY; TARGET CELLS;

BIOCHEMISTRY; BLOCK COPOLYMERS; BODY FLUIDS; DRUG DELIVERY; POLYETHYLENE GLYCOLS; RNA; TUMORS;

POLYETHYLENE OXIDES;

CHOLESTEROL; LUCIFERASE; MACROGOL; NUCLEASE; POLYLYSINE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; BREAST TUMOR; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; STABLE EXPRESSION;

ANIMALS; BODY WEIGHT; CELL DEATH; CELL LINE, TUMOR; CHOLESTEROL; EPITHELIAL CELLS; FEMALE; HUMANS; HYDRODYNAMICS; LUCIFERASES; MAMMARY NEOPLASMS, ANIMAL; MICE; POLYETHYLENE GLYCOLS; POLYLYSINE; RIBONUCLEASES; RNA, SMALL INTERFERING; TUMOR BURDEN;

MURINAE;

EID: 84876086765     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.021     Document Type: Article

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