메뉴 건너뛰기




Volumn 333, Issue 1, 2013, Pages 18-31

High aldehyde dehydrogenase activity enhances stem cell features in breast cancer cells by activating hypoxia-inducible factor-2α

Author keywords

Aldehyde dehydrogenase; Breast cancer; Cancer stem cell; Hypoxia inducible factor 2

Indexed keywords

ALDEHYDE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OCTAMER TRANSCRIPTION FACTOR 4;

EID: 84876086500     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.11.026     Document Type: Article
Times cited : (78)

References (62)
  • 3
    • 73149097698 scopus 로고    scopus 로고
    • Mammographic density and the risk of breast cancer recurrence after breast-conserving surgery
    • Cil T., Fishell E., Hanna W., Sun P., Rawlinson E., Narod S.A., McCready D.R. Mammographic density and the risk of breast cancer recurrence after breast-conserving surgery. Cancer 2009, 115:5780-5787.
    • (2009) Cancer , vol.115 , pp. 5780-5787
    • Cil, T.1    Fishell, E.2    Hanna, W.3    Sun, P.4    Rawlinson, E.5    Narod, S.A.6    McCready, D.R.7
  • 4
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M., Fojo T., Bates S. Tumour stem cells and drug resistance. Nat. Rev. Cancer 2005, 5:275-284.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 6
    • 67651031415 scopus 로고    scopus 로고
    • Cancer stem cells: a new paradigm for understanding tumor growth and progression and drug resistance
    • Gangemi R., Paleari L., Orengo A.M., Cesario A., Chessa L., Ferrini S., Russo P. Cancer stem cells: a new paradigm for understanding tumor growth and progression and drug resistance. Curr. Med. Chem. 2009, 16:1688-1703.
    • (2009) Curr. Med. Chem. , vol.16 , pp. 1688-1703
    • Gangemi, R.1    Paleari, L.2    Orengo, A.M.3    Cesario, A.4    Chessa, L.5    Ferrini, S.6    Russo, P.7
  • 8
    • 3042551383 scopus 로고    scopus 로고
    • Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism
    • Vasiliou V., Pappa A., Estey T. Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism. Drug Metab. Rev. 2004, 36:279-299.
    • (2004) Drug Metab. Rev. , vol.36 , pp. 279-299
    • Vasiliou, V.1    Pappa, A.2    Estey, T.3
  • 9
    • 67649884727 scopus 로고    scopus 로고
    • Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression
    • Morimoto K., Kim S.J., Tanei T., Shimazu K., Tanji Y., Taguchi T., Tamaki Y., Terada N., Noguchi S. Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression. Cancer Sci. 2009, 100:1062-1068.
    • (2009) Cancer Sci. , vol.100 , pp. 1062-1068
    • Morimoto, K.1    Kim, S.J.2    Tanei, T.3    Shimazu, K.4    Tanji, Y.5    Taguchi, T.6    Tamaki, Y.7    Terada, N.8    Noguchi, S.9
  • 11
    • 67449113764 scopus 로고    scopus 로고
    • Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers
    • Tanei T., Morimoto K., Shimazu K., Kim S.J., Tanji Y., Taguchi T., Tamaki Y., Noguchi S. Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin. Cancer Res. 2009, 15:4234-4241.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 4234-4241
    • Tanei, T.1    Morimoto, K.2    Shimazu, K.3    Kim, S.J.4    Tanji, Y.5    Taguchi, T.6    Tamaki, Y.7    Noguchi, S.8
  • 12
    • 84860347162 scopus 로고    scopus 로고
    • Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDH(hi)CD44 (+) human breast cancer cells
    • Croker A.K., Allan A.L. Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDH(hi)CD44 (+) human breast cancer cells. Breast Cancer Res. Treat. 2012, 133:75-87.
    • (2012) Breast Cancer Res. Treat. , vol.133 , pp. 75-87
    • Croker, A.K.1    Allan, A.L.2
  • 13
    • 58049221188 scopus 로고    scopus 로고
    • ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells
    • Moreb J.S., Baker H.V., Chang L.-J., Amaya M., Lopez M.C., Ostmark B., Chou W. ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells. Mol. Cancer 2008, 7:87.
    • (2008) Mol. Cancer , vol.7 , pp. 87
    • Moreb, J.S.1    Baker, H.V.2    Chang, L.-J.3    Amaya, M.4    Lopez, M.C.5    Ostmark, B.6    Chou, W.7
  • 16
    • 61849158175 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems
    • Levi B.P., Yilmaz O.H., Duester G., Morrison S.J. Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood 2009, 113:1670-1680.
    • (2009) Blood , vol.113 , pp. 1670-1680
    • Levi, B.P.1    Yilmaz, O.H.2    Duester, G.3    Morrison, S.J.4
  • 17
    • 79954417584 scopus 로고    scopus 로고
    • Molecular targeted therapy for hepatocellular carcinoma in the current and potential next strategies
    • Tanaka S., Arii S. Molecular targeted therapy for hepatocellular carcinoma in the current and potential next strategies. J. Gastroenterol. 2011, 46:289-296.
    • (2011) J. Gastroenterol. , vol.46 , pp. 289-296
    • Tanaka, S.1    Arii, S.2
  • 19
    • 77956224494 scopus 로고    scopus 로고
    • Oxygen in stem cell biology: a critical component of the stem cell niche
    • Mohyeldin A., Garzon-Muvdi T., Quinones-Hinojosa A. Oxygen in stem cell biology: a critical component of the stem cell niche. Cell Stem Cell 2010, 7:150-161.
    • (2010) Cell Stem Cell , vol.7 , pp. 150-161
    • Mohyeldin, A.1    Garzon-Muvdi, T.2    Quinones-Hinojosa, A.3
  • 20
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • Keith B., Simon M.C. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007, 129:465-472.
    • (2007) Cell , vol.129 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 23
    • 32444448861 scopus 로고    scopus 로고
    • Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
    • Vasiliou V., Nebert D.W. Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family. Hum. Genom. 2005, 2:138-143.
    • (2005) Hum. Genom. , vol.2 , pp. 138-143
    • Vasiliou, V.1    Nebert, D.W.2
  • 29
    • 77956355633 scopus 로고    scopus 로고
    • Int6/eIF3e silencing promotes functional blood vessel outgrowth and enhances wound healing by upregulating hypoxia-induced factor 2alpha expression
    • Chen L., Endler A., Uchida K., Horiguchi S., Morizane Y., Iijima O., Toi M., Shibasaki F. Int6/eIF3e silencing promotes functional blood vessel outgrowth and enhances wound healing by upregulating hypoxia-induced factor 2alpha expression. Circulation 2010, 122:910-919.
    • (2010) Circulation , vol.122 , pp. 910-919
    • Chen, L.1    Endler, A.2    Uchida, K.3    Horiguchi, S.4    Morizane, Y.5    Iijima, O.6    Toi, M.7    Shibasaki, F.8
  • 30
    • 33344468146 scopus 로고    scopus 로고
    • Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
    • Hess D.A., Wirthlin L., Craft T.P., Herrbrich P.E., Hohm S.A., Lahey R., Eades W.C., Creer M.H., Nolta J.A. Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood 2006, 107:2162-2169.
    • (2006) Blood , vol.107 , pp. 2162-2169
    • Hess, D.A.1    Wirthlin, L.2    Craft, T.P.3    Herrbrich, P.E.4    Hohm, S.A.5    Lahey, R.6    Eades, W.C.7    Creer, M.H.8    Nolta, J.A.9
  • 32
    • 79955593909 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform
    • Marcato P., Dean C.A., Giacomantonio C.A., Lee P.W. Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform. Cell Cycle 2011, 10:1378-1384.
    • (2011) Cell Cycle , vol.10 , pp. 1378-1384
    • Marcato, P.1    Dean, C.A.2    Giacomantonio, C.A.3    Lee, P.W.4
  • 36
    • 76149125786 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 A1-positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer
    • Su Y., Qiu Q., Zhang X., Jiang Z., Leng Q., Liu Z., Stass S.A., Jiang F. Aldehyde dehydrogenase 1 A1-positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer. Cancer Epidemiol. Biomarkers Prev. 2010, 19:327-337.
    • (2010) Cancer Epidemiol. Biomarkers Prev. , vol.19 , pp. 327-337
    • Su, Y.1    Qiu, Q.2    Zhang, X.3    Jiang, Z.4    Leng, Q.5    Liu, Z.6    Stass, S.A.7    Jiang, F.8
  • 37
    • 0026503190 scopus 로고
    • Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
    • Aslakson C.J., Miller F.R. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res. 1992, 52:1399-1405.
    • (1992) Cancer Res. , vol.52 , pp. 1399-1405
    • Aslakson, C.J.1    Miller, F.R.2
  • 41
    • 67349191354 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase as a marker for stem cells
    • Moreb J.S. Aldehyde dehydrogenase as a marker for stem cells. Curr. Stem Cell Res. Ther. 2008, 3:237-246.
    • (2008) Curr. Stem Cell Res. Ther. , vol.3 , pp. 237-246
    • Moreb, J.S.1
  • 43
    • 58049195459 scopus 로고    scopus 로고
    • Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population
    • Steiniger S.C., Coppinger J.A., Kruger J.A., Yates J., Janda K.D. Quantitative mass spectrometry identifies drug targets in cancer stem cell-containing side population. Stem Cells 2008, 26:3037-3046.
    • (2008) Stem Cells , vol.26 , pp. 3037-3046
    • Steiniger, S.C.1    Coppinger, J.A.2    Kruger, J.A.3    Yates, J.4    Janda, K.D.5
  • 44
    • 54249086214 scopus 로고    scopus 로고
    • The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis
    • Vaillant F., Asselin-Labat M.L., Shackleton M., Forrest N.C., Lindeman G.J., Visvader J.E. The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis. Cancer Res. 2008, 68:7711-7717.
    • (2008) Cancer Res. , vol.68 , pp. 7711-7717
    • Vaillant, F.1    Asselin-Labat, M.L.2    Shackleton, M.3    Forrest, N.C.4    Lindeman, G.J.5    Visvader, J.E.6
  • 45
    • 62449205665 scopus 로고    scopus 로고
    • Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
    • Dallas N.A., Xia L., Fan F., Gray M.J., Gaur P., van Buren G., Samuel S., Kim M.P., Lim S.J., Ellis L.M. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res. 2009, 69:1951-1957.
    • (2009) Cancer Res. , vol.69 , pp. 1951-1957
    • Dallas, N.A.1    Xia, L.2    Fan, F.3    Gray, M.J.4    Gaur, P.5    van Buren, G.6    Samuel, S.7    Kim, M.P.8    Lim, S.J.9    Ellis, L.M.10
  • 46
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 48
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Liu S., Wicha M.S. Targeting breast cancer stem cells. J. Clin. Oncol. 2010, 28:4006-4012.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 49
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston J.M., Li Z., McLendon R.E., Hjelmeland A.B., Rich J.N. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009, 8:3274-3284.
    • (2009) Cell Cycle , vol.8 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3    Hjelmeland, A.B.4    Rich, J.N.5
  • 51
    • 53049104709 scopus 로고    scopus 로고
    • Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis
    • Hu T., Liu S., Breiter D.R., Wang F., Tang Y., Sun S. Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res. 2008, 68:6533-6540.
    • (2008) Cancer Res. , vol.68 , pp. 6533-6540
    • Hu, T.1    Liu, S.2    Breiter, D.R.3    Wang, F.4    Tang, Y.5    Sun, S.6
  • 52
    • 84857935029 scopus 로고    scopus 로고
    • OCT4 expression enhances features of cancer stem cells in a mouse model of breast cancer
    • Kim R.J., Nam J.S. OCT4 expression enhances features of cancer stem cells in a mouse model of breast cancer. Lab. Anim. Res. 2011, 27:147-152.
    • (2011) Lab. Anim. Res. , vol.27 , pp. 147-152
    • Kim, R.J.1    Nam, J.S.2
  • 53
    • 78650401560 scopus 로고    scopus 로고
    • HIF-2alpha enhances beta-catenin/TCF-driven transcription by interacting with beta-catenin
    • Choi H., Chun Y.S., Kim T.Y., Park J.W. HIF-2alpha enhances beta-catenin/TCF-driven transcription by interacting with beta-catenin. Cancer Res. 2010, 70:10101-10111.
    • (2010) Cancer Res. , vol.70 , pp. 10101-10111
    • Choi, H.1    Chun, Y.S.2    Kim, T.Y.3    Park, J.W.4
  • 54
    • 0141629530 scopus 로고    scopus 로고
    • Granzyme B: pro-apoptotic, antiviral and antitumor functions
    • Trapani J.A., Sutton V.R. Granzyme B: pro-apoptotic, antiviral and antitumor functions. Curr. Opin. Immunol. 2003, 15:533-543.
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 533-543
    • Trapani, J.A.1    Sutton, V.R.2
  • 57
    • 0028815621 scopus 로고
    • Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper
    • Nobel C.I., Kimland M., Lind B., Orrenius S., Slater A.F. Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper. J. Biol. Chem. 1995, 270:26202-26208.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26202-26208
    • Nobel, C.I.1    Kimland, M.2    Lind, B.3    Orrenius, S.4    Slater, A.F.5
  • 58
    • 77950212486 scopus 로고    scopus 로고
    • Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species
    • Jin Y., Lu Z., Ding K., Li J., Du X., Chen C., Sun X., Wu Y., Zhou J., Pan J. Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. Cancer Res. 2010, 70:2516-2527.
    • (2010) Cancer Res. , vol.70 , pp. 2516-2527
    • Jin, Y.1    Lu, Z.2    Ding, K.3    Li, J.4    Du, X.5    Chen, C.6    Sun, X.7    Wu, Y.8    Zhou, J.9    Pan, J.10
  • 60
    • 33751285781 scopus 로고    scopus 로고
    • Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity
    • Chen D., Cui Q.C., Yang H., Dou Q.P. Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity. Cancer Res. 2006, 66:10425-10433.
    • (2006) Cancer Res. , vol.66 , pp. 10425-10433
    • Chen, D.1    Cui, Q.C.2    Yang, H.3    Dou, Q.P.4
  • 61
    • 79957440998 scopus 로고    scopus 로고
    • The hypoxia-associated factor switches cells from HIF-1alpha- to HIF-2alpha-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion
    • Koh M.Y., Lemos R., Liu X., Powis G. The hypoxia-associated factor switches cells from HIF-1alpha- to HIF-2alpha-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion. Cancer Res. 2011, 71:4015-4027.
    • (2011) Cancer Res. , vol.71 , pp. 4015-4027
    • Koh, M.Y.1    Lemos, R.2    Liu, X.3    Powis, G.4
  • 62
    • 84655161946 scopus 로고    scopus 로고
    • HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression
    • Keith B., Johnson R.S., Simon M.C. HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat. Rev. Cancer 2011, 12:9-22.
    • (2011) Nat. Rev. Cancer , vol.12 , pp. 9-22
    • Keith, B.1    Johnson, R.S.2    Simon, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.