Polar or apolar - The role of polarity for urea-induced protein denaturation

PLoS Computational Biology

Volumn 4, Issue 11, 2008, Pages

  Stumpe, Martin C ^a   Grubmüller, Helmut ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL CHEMISTRY; DENATURATION; METABOLISM; MOLECULAR DYNAMICS; PROTEINS; SOLUTIONS;

DRIVING FORCES; HYDROPHOBIC INTERACTIONS; INDUCED PROTEINS; MOLECULAR MECHANISM; POLAR INTERACTIONS; PROTEIN DENATURATION; PROTEIN FOLDINGS; PROTEIN STABILITY; PROTEIN SURFACE; UNFOLDINGS;

UREA;

AMINO ACID; UREA; PROTEIN; SOLVENT; WATER;

AQUEOUS SOLUTION; ARTICLE; FORCE; HYDROPHOBICITY; MATHEMATICAL COMPUTING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SIMULATION; STRUCTURE ANALYSIS; CHEMISTRY; COMPUTER SIMULATION; DRUG EFFECT; METABOLISM; PROTEIN CONFORMATION; SURFACE PROPERTY;

AMINO ACIDS; COMPUTER SIMULATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEINS; SOLVENTS; SURFACE PROPERTIES; UREA; WATER;

EID: 57149110439     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000221     Document Type: Article

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