Immune cells perturb axons and impair neuronal survival in a mouse model of infantile neuronal ceroid lipofuscinosis

Brain

Volumn 136, Issue 4, 2013, Pages 1083-1101

  Groh, Janos ^a   Kühl, Thomas G ^b   Ip, Chi Wang ^a   Nelvagal, Hemanth R ^b   Sri, Sarmi ^b   Duckett, Steven ^b   Mirza, Myriam ^c   Langmann, Thomas ^c,d   Cooper, Jonathan D ^b   Martini, Rudolf ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

axonal damage; neurodegeneration; neuroinflammation; neuronal ceroid lipofuscinosis; T lymphocytes

Indexed keywords

CD8 ANTIGEN; PALMITOYL PROTEIN THIOESTERASE; PALMITOYL PROTEIN THIOESTERASE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; INFLAMMATORY CELL; LIPOFUSCINOSIS; LONGEVITY; MACROPHAGE; MICROGLIA; MOUSE; NERVE CELL; NERVE FIBER; NEURONAL CEROID LIPOFUSCINOSIS INFANTILE FINNISH TYPE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RETINA GANGLION CELL; VISUAL ACUITY; VISUAL SYSTEM;

EID: 84876059193     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt020     Document Type: Article

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