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Volumn 30, Issue 2, 2010, Pages 319-326

Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells

Author keywords

Apoptosis; Cell cycle distribution; Cell proliferation; Cell transformation; DNA repair enzymes; HBx; Hepatocytes

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYGUANINE; DNA GLYCOSYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS X PROTEIN;

EID: 77950600868     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2009.02167.x     Document Type: Article
Times cited : (32)

References (37)
  • 1
    • 5044234897 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis
    • Anzola M. Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis. J Viral Hepat 2004, 11:383-93.
    • (2004) J Viral Hepat , vol.11 , pp. 383-393
    • Anzola, M.1
  • 2
    • 0034928111 scopus 로고    scopus 로고
    • Hepatitis B virus and hepatocellular carcinoma
    • Arbuthnot P, Kew M. Hepatitis B virus and hepatocellular carcinoma. Int J Exp Pathol 2001, 82:77-100.
    • (2001) Int J Exp Pathol , vol.82 , pp. 77-100
    • Arbuthnot, P.1    Kew, M.2
  • 3
    • 33646337650 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and hepatitis B virus
    • Chan HL, Sung JJ. Hepatocellular carcinoma and hepatitis B virus. Semin Liver Dis 2006, 26:153-61.
    • (2006) Semin Liver Dis , vol.26 , pp. 153-161
    • Chan, H.L.1    Sung, J.J.2
  • 4
    • 33645453504 scopus 로고    scopus 로고
    • Differentially expressed genes associated with hepatitis B virus HBx and MHBs protein function in hepatocellular carcinoma
    • Kim DG. Differentially expressed genes associated with hepatitis B virus HBx and MHBs protein function in hepatocellular carcinoma. Methods Mol Biol 2006, 317:141-55.
    • (2006) Methods Mol Biol , vol.317 , pp. 141-155
    • Kim, D.G.1
  • 5
    • 33846473749 scopus 로고    scopus 로고
    • Hepatitis B virus-induced oncogenesis
    • Lupberger J, Hildt E. Hepatitis B virus-induced oncogenesis. World J Gastroenterol 2007, 13:74-81.
    • (2007) World J Gastroenterol , vol.13 , pp. 74-81
    • Lupberger, J.1    Hildt, E.2
  • 6
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • Tang H, Oishi N, Kaneko S, Murakami S. Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci 2006, 97:977-83.
    • (2006) Cancer Sci , vol.97 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 7
    • 8644274040 scopus 로고    scopus 로고
    • The enigmatic X gene of hepatitis B virus
    • Bouchard MJ, Schneider RJ. The enigmatic X gene of hepatitis B virus. J Virol 2004, 78:12725-34.
    • (2004) J Virol , vol.78 , pp. 12725-12734
    • Bouchard, M.J.1    Schneider, R.J.2
  • 8
    • 32244445762 scopus 로고    scopus 로고
    • Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells
    • Chan DW, Ng IO. Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells. J Pathol 2006, 208:372-80.
    • (2006) J Pathol , vol.208 , pp. 372-380
    • Chan, D.W.1    Ng, I.O.2
  • 9
    • 0034753082 scopus 로고    scopus 로고
    • Hepatitis B virus X protein: a multifunctional viral regulator
    • Murakami S. Hepatitis B virus X protein: a multifunctional viral regulator. J Gastroenterol 2001, 36:651-60.
    • (2001) J Gastroenterol , vol.36 , pp. 651-660
    • Murakami, S.1
  • 10
    • 31944438515 scopus 로고    scopus 로고
    • Effects of hepatitis B virus X protein on the development of liver cancer
    • Zhang X, Zhang H, Ye L. Effects of hepatitis B virus X protein on the development of liver cancer. J Lab Clin Med 2006, 147:58-66.
    • (2006) J Lab Clin Med , vol.147 , pp. 58-66
    • Zhang, X.1    Zhang, H.2    Ye, L.3
  • 11
    • 0034964333 scopus 로고    scopus 로고
    • Subcellular localisation of the X protein in HBV infected hepatocytes
    • Hoare J, Henkler F, Dowling JJ. Subcellular localisation of the X protein in HBV infected hepatocytes. J Med Virol 2001, 64:419-26.
    • (2001) J Med Virol , vol.64 , pp. 419-426
    • Hoare, J.1    Henkler, F.2    Dowling, J.J.3    et al4
  • 12
    • 0031898616 scopus 로고    scopus 로고
    • Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas
    • Su Q, Schroder CH, Hofmann WJ. Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas. Hepatology 1998, 27:1109-20.
    • (1998) Hepatology , vol.27 , pp. 1109-1120
    • Su, Q.1    Schroder, C.H.2    Hofmann, W.J.3    et al4
  • 13
    • 0025907983 scopus 로고
    • HBx gene of hepatitis B virus induces liver cancer in transgenic mice
    • Kim CM, Koike K, Saito I, Miyamura T, Jay G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991, 351:317-20.
    • (1991) Nature , vol.351 , pp. 317-320
    • Kim, C.M.1    Koike, K.2    Saito, I.3    Miyamura, T.4    Jay, G.5
  • 14
    • 0028230728 scopus 로고
    • High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice
    • Koike K, Moriya K, Iino S. High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice. Hepatology 1994, 19:810-9.
    • (1994) Hepatology , vol.19 , pp. 810-819
    • Koike, K.1    Moriya, K.2    Iino, S.3    et al4
  • 15
    • 0035084167 scopus 로고    scopus 로고
    • Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions
    • Madden CR, Finegold MJ, Slagle BL. Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions. J Virol 2001, 75:3851-8.
    • (2001) J Virol , vol.75 , pp. 3851-3858
    • Madden, C.R.1    Finegold, M.J.2    Slagle, B.L.3
  • 16
    • 17144474720 scopus 로고    scopus 로고
    • Long-term expression of the hepatitis B virus core-e- and X-proteins does not cause pathologic changes in transgenic mice
    • Reifenberg K, Lohler J, Pudollek HP. Long-term expression of the hepatitis B virus core-e- and X-proteins does not cause pathologic changes in transgenic mice. J Hepatol 1997, 26:119-30.
    • (1997) J Hepatol , vol.26 , pp. 119-130
    • Reifenberg, K.1    Lohler, J.2    Pudollek, H.P.3    et al4
  • 17
    • 0031035764 scopus 로고    scopus 로고
    • The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice
    • Terradillos O, Billet O, Renard CA. The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice. Oncogene 1997, 14:395-404.
    • (1997) Oncogene , vol.14 , pp. 395-404
    • Terradillos, O.1    Billet, O.2    Renard, C.A.3    et al4
  • 18
    • 0034774463 scopus 로고    scopus 로고
    • Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress
    • Waris G, Huh KW, Siddiqui A. Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress. Mol Cell Biol 2001, 21:7721-30.
    • (2001) Mol Cell Biol , vol.21 , pp. 7721-7730
    • Waris, G.1    Huh, K.W.2    Siddiqui, A.3
  • 20
    • 4344577088 scopus 로고    scopus 로고
    • Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents
    • Achanta G, Huang P. Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents. Cancer Res 2004, 64:6233-9.
    • (2004) Cancer Res , vol.64 , pp. 6233-6239
    • Achanta, G.1    Huang, P.2
  • 21
    • 0031442418 scopus 로고    scopus 로고
    • Cigarette smoking and histologic type of lung cancer in men
    • Barbone F, Bovenzi M, Cavallieri F, Stanta G. Cigarette smoking and histologic type of lung cancer in men. Chest 1997, 112:1474-9.
    • (1997) Chest , vol.112 , pp. 1474-1479
    • Barbone, F.1    Bovenzi, M.2    Cavallieri, F.3    Stanta, G.4
  • 22
    • 0034708226 scopus 로고    scopus 로고
    • Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
    • Bruner SD, Norman DP, Verdine GL. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature 2000, 403:859-66.
    • (2000) Nature , vol.403 , pp. 859-866
    • Bruner, S.D.1    Norman, D.P.2    Verdine, G.L.3
  • 23
    • 0034008801 scopus 로고    scopus 로고
    • Increase in mutation frequency in lung of Big Blue rat by exposure to diesel exhaust
    • Sato H, Sone H, Sagai M, Suzuki KT, Aoki Y. Increase in mutation frequency in lung of Big Blue rat by exposure to diesel exhaust. Carcinogenesis 2000, 21:653-61.
    • (2000) Carcinogenesis , vol.21 , pp. 653-661
    • Sato, H.1    Sone, H.2    Sagai, M.3    Suzuki, K.T.4    Aoki, Y.5
  • 24
    • 0030220956 scopus 로고    scopus 로고
    • Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily
    • Nash HM, Bruner SD, Scharer OD. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Curr Biol 1996, 6:968-80.
    • (1996) Curr Biol , vol.6 , pp. 968-980
    • Nash, H.M.1    Bruner, S.D.2    Scharer, O.D.3    et al4
  • 25
    • 0029896229 scopus 로고    scopus 로고
    • Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine
    • van der Kemp PA, Thomas D, Barbey R, de Oliveira R, Boiteux S. Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. Proc Natl Acad Sci USA 1996, 93:5197-202.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5197-5202
    • van der Kemp, P.A.1    Thomas, D.2    Barbey, R.3    de Oliveira, R.4    Boiteux, S.5
  • 26
    • 0032840464 scopus 로고    scopus 로고
    • Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein
    • Slupska MM, Luther WM, Chiang JH, Yang H, Miller JH. Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein. J Bacteriol 1999, 181:6210-3.
    • (1999) J Bacteriol , vol.181 , pp. 6210-6213
    • Slupska, M.M.1    Luther, W.M.2    Chiang, J.H.3    Yang, H.4    Miller, J.H.5
  • 27
    • 77950602574 scopus 로고
    • Ultrastructures of LO2 normal adult hepatocytes over successive in vitro cultures
    • Ye XZ, Zhu DH, Shen DW. Ultrastructures of LO2 normal adult hepatocytes over successive in vitro cultures. Acta Biol Exp Sin 1980, 13:3612-41.
    • (1980) Acta Biol Exp Sin , vol.13 , pp. 3612-3641
    • Ye, X.Z.1    Zhu, D.H.2    Shen, D.W.3
  • 29
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science 1988, 241:58-62.
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 30
    • 0030043457 scopus 로고    scopus 로고
    • Measurement of 8-OHdG in DNA by HPLC/ECD: the importance of DNA purity
    • Laws GM, Adams SP. Measurement of 8-OHdG in DNA by HPLC/ECD: the importance of DNA purity. Biotechniques 1996, 20:36-8.
    • (1996) Biotechniques , vol.20 , pp. 36-38
    • Laws, G.M.1    Adams, S.P.2
  • 31
    • 0027370365 scopus 로고
    • The value of hepatitis B x antigen as a prognostic marker in the development of hepatocellular carcinoma
    • Zhu M, London WT, Duan LX, Feitelson MA. The value of hepatitis B x antigen as a prognostic marker in the development of hepatocellular carcinoma. Int J Cancer 1993, 55:571-6.
    • (1993) Int J Cancer , vol.55 , pp. 571-576
    • Zhu, M.1    London, W.T.2    Duan, L.X.3    Feitelson, M.A.4
  • 32
    • 0026783165 scopus 로고
    • Hepatitis B X-gene expression in hepatocellular carcinoma
    • Diamantis ID, McGandy CE, Chen TJ. Hepatitis B X-gene expression in hepatocellular carcinoma. J Hepatol 1992, 15:400-3.
    • (1992) J Hepatol , vol.15 , pp. 400-403
    • Diamantis, I.D.1    McGandy, C.E.2    Chen, T.J.3    et al4
  • 33
    • 33749422076 scopus 로고    scopus 로고
    • Functional switch of viral protein HBx on cell apoptosis, transformation, and tumorigenesis in association with oncoprotein Ras
    • Wei W, Huang W, Pan Y, Zhu F, Wu J. Functional switch of viral protein HBx on cell apoptosis, transformation, and tumorigenesis in association with oncoprotein Ras. Cancer Lett 2006, 244:119-28.
    • (2006) Cancer Lett , vol.244 , pp. 119-128
    • Wei, W.1    Huang, W.2    Pan, Y.3    Zhu, F.4    Wu, J.5
  • 34
    • 0030041821 scopus 로고    scopus 로고
    • Hepadnaviral X protein: review of recent progress
    • Yen TS. Hepadnaviral X protein: review of recent progress. J Biomed Sci 1996, 3:20-30.
    • (1996) J Biomed Sci , vol.3 , pp. 20-30
    • Yen, T.S.1
  • 35
    • 0031932893 scopus 로고    scopus 로고
    • Hepatitis B virus pX targets TFIIB in transcription coactivation
    • Haviv I, Shamay M, Doitsh G, Shaul Y. Hepatitis B virus pX targets TFIIB in transcription coactivation. Mol Cell Biol 1998, 18:1562-9.
    • (1998) Mol Cell Biol , vol.18 , pp. 1562-1569
    • Haviv, I.1    Shamay, M.2    Doitsh, G.3    Shaul, Y.4
  • 36
    • 14544306104 scopus 로고    scopus 로고
    • Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells
    • Zhang X, Dong N, Zhang H. Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells. J Lab Clin Med 2005, 145:98-104.
    • (2005) J Lab Clin Med , vol.145 , pp. 98-104
    • Zhang, X.1    Dong, N.2    Zhang, H.3    et al4
  • 37
    • 18544392795 scopus 로고    scopus 로고
    • Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma
    • Jungst C, Cheng B, Gehrke R. Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma. Hepatology 2004, 39:1663-72.
    • (2004) Hepatology , vol.39 , pp. 1663-1672
    • Jungst, C.1    Cheng, B.2    Gehrke, R.3    et al4


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