Genome-wide analysis of DNA methylation in rat lungs with lipopolysaccharide-induced acute lung injury

Molecular Medicine Reports

Volumn 7, Issue 5, 2013, Pages 1417-1424

  Zhang, Xiao Qiang ^a   Lv, Chang Jun ^a   Liu, Xiang Yong ^a   Hao, Dong ^a   Qin, Jing ^a   Tian, Huan Huan ^a   Li, Yan ^a   Wang, Xiao Zhi ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; CpG island; DNA methylation; Lipopolysaccharide; Promoter

Indexed keywords

CASPASE 3; CCAAT ENHANCER BINDING PROTEIN BETA; CXCL2 CHEMOKINE; DIPEPTIDYL CARBOXYPEPTIDASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE MIGRATION INHIBITION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN LIGHT CHAIN KINASE; P21 ACTIVATED KINASE 1; RAC PROTEIN; RAS PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; VASCULOTROPIN B;

ACUTE LUNG INJURY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHROMOSOME 1; CHROMOSOME 10; CHROMOSOME 3; CHROMOSOME 5; CHROMOSOME 7; CONTROLLED STUDY; CPG ISLAND; DENSITY; DNA METHYLATION; DNA MICROARRAY; ENZYME REGULATION; GENE; GENETIC ASSOCIATION; HISTOLOGY; IMMUNOPRECIPITATION; LUNG; MALE; MICROARRAY ANALYSIS; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ACUTE LUNG INJURY; ANIMALS; CHROMOSOMES, MAMMALIAN; CPG ISLANDS; DNA METHYLATION; GENETIC ASSOCIATION STUDIES; GENOME; HUMANS; LIPOPOLYSACCHARIDES; LUNG; MALE; MOLECULAR SEQUENCE ANNOTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; RESPIRATORY DISTRESS SYNDROME, ADULT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

RATTUS;

EID: 84875982397     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1405     Document Type: Article

References (31)

1. Rubenfeld GD, Caldwell E, Peabody E, et al: Incidence and outcomes of acute lung injury. N Engl J Med 353: 1685-1693, 2005.
2. Zambon M and Vincent JL: Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 133: 1120-1127, 2008.
3. Wang HM, Bodenstein M and Markstaller K: Overview of the patolgy of three widely used animal models of acute lung injury. Eur Surg Res 40: 305-316, 2008.
4. El Gazzar M, Yoza BK, Hu JY, Cousart SL and McCall CE: Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance. J Biol Chem 282: 26857-26864, 2007.
5. Angrisano T, Pero R, Peluso S, et al: LPS-induced IL-8 activation in human intestinal epithelial cells is accompanied by specific histone H3 acetylation and methylation changes. BMC Microbiol 10: 172, 2010.
6. Tatemichi M, Hata H, Tazawa H and Nakadate T: Lipopolysaccharide induces aberrant hypermethylation of Hic-1 in mouse embryonic fibroblasts lacking p53. Anticancer Res 28: 2101-2108, 2008.
7. Kiefer JC: Epigenetics in development. Dev Dyn 236: 1144-1156, 2007.
8. Holliday R and Pugh JE: DNA modification mechanisms and gene activity during development. Science 187: 226-232, 1975.
9. Leonhardt H and Bestor TH: Structure, function and regulation of mammalian DNA methyltransferase. EXS 64: 109-119, 1993.
10. Klose RJ and Bird AP: Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31: 89-97, 2006.
11. Heller G, Zielinski CC and Zöchbauer-Müller S: Lung cancer: from single-gene methylation to methylome profiling. Cancer Metastasis Rev 29: 95-107, 2010.
12. Adcock IM, Tsaprouni L, Bhavsar P and Ito K: Epigenetic regulation of airway inflammation. Curr Opin Immunol 19: 694-700, 2007.
13. Boellmann F, Zhang L, Clewell HJ, Schroth GP, Kenyon EM Andersen ME and Thomas RS: Genome-wide analysis of DNA methylation and gene expression changes in the mouse lung following subchronic arsenate exposure. Toxicol Sci 117: 404-417, 2010.
14. Jia RZ, Zhang X, HU P, Liu XM, Hua XD, Wang X and Ding HJ: Screening for differential methylation status in human placenta in preeclampsia using a CpG island plus promoter microarray. Int J Mol Med 30: 133-141, 2012.
15. Flores C, Pino-Yanes MM and Villar J: A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury. Crit Care 12: R130, 2008.
16. Di Paola R, Cisafulli C, Mazzon E, Genovese T, Paterniti I, Bramanti P and Cuzzocrea S: Effect of PD98059, a selective MAPK3/MAPK1 inhibitor, on acute lung injury in mice. Int J Immunopathol Pharmacol 22: 937-950, 2009.
17. Grigoryev DN, Finigan JH, Hassoun P and Garcia JG: Science review: searching for gene candidates in acute lung injury. Crit Care 8: 440-447, 2004.
18. Yao HY, Chen L and Xu C: Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice. Biochim Biophys Acta 1810: 666-674, 2011.
19. Flores C, Pino-Yanes MM, Casula M, Casula M and Villar J: Genetics of acute lung injury: past, present and future. Minerva Anestesiol 76: 860-864, 2010.
20. Saxonov S, Berg P and Brutlag DL: A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci USA 103: 1412-1417, 2006.
21. Adamzik M, Frey U, Sixt S, Knemeyer L, Beiderlinden M, Peters J and Siffert W: ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS. Eur Respir J 29: 482-488, 2007.
22. Mura M, dos Santos CC, Stewart D and Liu M: Vascular endothelial growth factor and related molecules in acute lung injury. J Appl Physiol 97: 1605-1617, 2004.
23. Yan C, Wu M, Cao J, Tang H, Zhu M, Johnson PF and Gao H: Critical role for CCAAT/enhancer-binding protein β in immune complex-induced acute lung injury. J Immunol 189: 1480-1490, 2012.
24. Belperio JA, Keane MP, Burdick MD, et al: Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest 110: 1703-1716, 2002.
25. Flores C, Ma SF, Maresso K, Wade MS, Villar J and Garcia JG: IL-6 gene-wide haplotype is association with susceptibility to acute lung injury. Transl Res 152: 11-17, 2008.
26. Han YJ, Ma SF, Wade MS, Flores C and Garcia JG: An intronic MYLK variant associated with inflammatory lung disease regulates promoter activity of the smooth muscle myosin light chain kinase isoform. J Mol (Berl) 90: 299-308, 2012.
27. Takahashi K, Koga K, Linge HM, et al: Macrophage CD74 contributes to MIF-induced pulmonary inflammation. Respir Res 10: 33, 2009.
28. Ikegami M, Falcone A and Whitsett JA: STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury. J Appl Physiol 104: 1753-1760, 2008.
29. Perl M, Chung CS, Perl U, Thakkar R, Lomas-Neira J and Ayala A: Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury. Crit Care Med 38: 1179-1186, 2010.
30. Birukova AA, Xing J, Fu P, et al: Atrial natriuretic peptide attenuates LPS-induced vascular leak: role of PAK1. Am J Physiol Lung Cell Mol Physiol 299: L652-L663, 2010.
31. Leite-Junior JH, Garcia CS, Souza-Fernandes AB, et al: Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice. Crit Care Med 36: 2621-2628, 2008.