Screening for differential methylation status in human placenta in preeclampsia using a CpG island plus promoter microarray

International Journal of Molecular Medicine

Volumn 30, Issue 1, 2012, Pages 133-141

  Jia, Rui Zhe ^a   Zhang, Xiang ^a   Hu, Ping ^a   Liu, Xiao Mei ^a   Hua, Xiang Dong ^a   Wang, Xin ^a   Ding, Hong Juan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

CpG promoter microarray; DNA methylation; Placenta; Pre eclampsia

Indexed keywords

BISULFITE; CXCL1 CHEMOKINE; TRANSCRIPTION FACTOR CDX1; TRANSCRIPTION FACTOR SOX7;

ADORA2B GENE; ADULT; ARTICLE; CAPN2 GENE; CHROMOSOME 1; CHROMOSOME 12; CHROMOSOME 19; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPHX2 GENE; FEMALE; GENE; HUMAN; IMMUNOPRECIPITATION; MICROARRAY ANALYSIS; PLACENTA; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PRIORITY JOURNAL; SCREENING;

ADULT; CHROMOSOME MAPPING; CPG ISLANDS; DNA METHYLATION; FEMALE; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS; PROMOTER REGIONS, GENETIC;

EID: 84861464009     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.983     Document Type: Article

References (32)

1. Lain KY and Roberts JM: Contemporary concepts of the pathogenesis and management of preeclampsia. JAMA 287: 3183-3186, 2002. (Pubitemid 34686089)
2. Myatt L: Role of placenta in preeclampsia. Endocrine 19: 103-111, 2002.
3. Maccani MA and Marsit CJ: Epigenetics in the placenta. Am J Reprod Immunol 62: 78-89, 2009.
4. Nelissen EC, van Montfoort AP, Dumoulin JC and Evers JL: Epigenetics and the placenta. Hum Reprod update 17: 397-417, 2011.
5. Yuen RK, Avila L, Peńaherrera MS, von Dadelszen P, Lefebvre L, Kobor MS and Robinson WP: Human placental-specific epipolymorphism and its association with adverse pregnancy outcomes. PLoS One 4: e7389, 2009.
6. American College of Obstetricians and Gynecologists; Committee on Practice Bulletins: Obstetrics. ACOG practice bulletin no. 33: diagnosis and management of preeclampsia and eclampsia. Obstet Gynecol 99: 159-167, 2002.
7. National Institutes of Health; National Heart, Lung and Blood Institute; National High Blood Pressure Education Program: Working group report on high blood pressure in pregnancy. NIH Publication no. 00-3029, revised July 2000. NIH, Bethesda, MD, 2000.
8. Li LC. Designing PCR primer for DNA methylation mapping. Methods Mol Biol 402: 371-384, 2007.
9. Tong WG, Wierda WG, Lin E, Kuang SQ, Bekele BN, Estrov Z, Wei Y, Yang H, Keating MJ and Garcia-Manero G: Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics 5: 499-508, 2010.
10. Zhao X, Li J, Zhuo J and Cai L: Reexpression of ARHI inhibits tumor growth and angiogenesis and impairs the mTOR/VEGF pathway in hepatocellular carcinoma. Biochem Biophys Res Commun 403: 417-421, 2010.
11. He M, Han M, Zheng B, Shu YN and Wen JK: Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cells. J Biochem 146: 683-691, 2009.
12. Kida T, Chuma H, Murata T, Yamawaki H, Matsumoto S, Hori M and Ozaki H: Chronic treatment with PDGF-BB and endothelin- 1 synergistically induces vascular hyperplasia and loss of contractility in organ-cultured rat tail artery. Atherosclerosis 214: 288-294, 2011.
13. Cross JC: The genetics of pre-eclampsia: a feto-placental or maternal problem? Clin Genet 64: 96-103, 2003.
14. Troisi R, Braekke K, Harsem NK, Hyer M, Hoover RN and Staff AC: Blood pressure augmentation and maternal circulating concentrations of angiogenic factors at delivery in preeclamptic and uncomplicated pregnancies. Am J Obstet Gynecol 199: 653, 2008.
15. Kulkarni AV, Mehendale SS, Yadav HR, Kilari AS, Taralekar VS and Joshi SR: Circulating angiogenic factors and their association with birth outcomes in preeclampsia. Hypertens Res 33: 561-567, 2010.
16. Park H, Choi HJ, Kim J, Kim M, Rho SS, Hwang D, Kim YM and Kwon YG: Homeobox D1 regulates angiogenic functions of endothelial cells via integrin &beta1 expression. Biochem Biophys Res Commun 408: 186-192, 2011.
17. Baston-Büst DM, Götte M, Janni W, Krüssel JS and Hess AP: Syndecan-1 knock-down in decidualized human endometrial stromal cells leads to significant changes in cytokine and angiogenic factor expression patterns. Reprod Biol Endocrinol 8: 133, 2010.
18. Red-Horse K, Kapidzic M, Zhou Y, Feng KT, Singh H and Fisher SJ: EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation. Development 132: 4097-4106, 2005. (Pubitemid 41488859)
19. Monkley SJ, Delaney SJ, Pennisi DJ, Christiansen JH and Wainwright BJ: Targeted disruption of the Wnt2 gene results in placentation defects. Development 122: 3343-3353, 1996. (Pubitemid 26395977)
20. Savory JG, Bouchard N, Pierre V, Rijli FM, De Repentigny Y, Kothary R and Lohnes D: Cdx2 regulation of posterior development through non-Hox targets. Development 136: 4099-4110, 2009.
21. Tsai CT, Lai LP, Hwang JJ and Lin JL: Chiang FT. Molecular genetics of atrial fibrillation. J Am Coll Cardiol 52: 241-250, 2008.
22. Jin HS, Hong KW, Lim JE, Hwang SY, Lee SH, Shin C, Park HK and Oh B: Genetic variations in the sodium balance-regulating genes ENaC, NEDD4L, NDFIP2 and USP2 influence blood pressure and hypertension. Kidney Blood Press Res 33: 15-23, 2010.
23. Ashenagar MS, Tabuchi M, Kinoshita K, Ooshima K, Niwa A, Watanabe Y, Yoshida M, Shimada K, Yasunaga T, Yamanishi H and Higashino H: Gene expression in the adrenal glands of three spontaneously hypertensive rat substrains. Mol Med Rep 3: 213-222, 2010.
24. Wu HY, Tomizawa K and Matsui H: Calpain-calcineurin signaling in the pathogenesis of calcium-dependent disorder. Acta Med Okayama 61: 123-137, 2007. (Pubitemid 47052599)
25. Dolinoy DC, Weidman JR and Jirtle RL: Epigenetic gene regulation: linking early developmental environment to adult disease. Reprod Toxicol 23: 297-307, 2007. (Pubitemid 46602921)
26. Xie F, Hu Y, Speert DP, Turvey SE, Peng G, Money DM, Magee LA and von Dadelszen P: Toxaemia Study Group: Toll-like receptor gene polymorphisms and preeclampsia risk: a case-control study and data synthesis. Hypertens Pregnancy 29: 390-398, 2010.
27. Hauth JC, Clifton RG, Roberts JM, Myatt L, Spong CY, Leveno KJ, Varner MW, Wapner RJ, Thorp JM Jr, Mercer BM, et al: Maternal insulin resistance and preeclampsia. Am J Obstet Gynecol 204: 327, 2011.
28. Tokumura A, Kume T, Taira S, Yasuda K and Kanzaki H: Altered activity of lysophospholipase D, which produces bioactive lysophosphatidic acid and choline, in serum from women with pathological pregnancy. Mol Hum Reprod 15: 301-310, 2009.
29. Yuen RK, Peńaherrera MS, von Dadelszen P, McFadden DE and Robinson WP: DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in earlyonset preeclampsia. Eur J Hum Genet 18: 1006-1012, 2010.
30. Bellido ML, Radpour R, Lapaire O, De Bie I, Hösli I, Bitzer J, Hmadcha A, Zhong XY and Holzgreve W: MALDI-TOF mass array analysis of RASSF1A and SERPINB5 methylation patterns in human placenta and plasma. Biol Reprod 82: 745-750, 2010.
31. Kulkarni A, Chavan-Gautam P, Mehendale S, Yadav H and Joshi S: Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia. DNA Cell Biol 30: 79-84, 2011.
32. Gao WL, Li D, Xiao ZX, Liao QP, Yang HX, Li YX, Ji L and Wang YL: Detection of global DNA methylation and paternally imprinted H19 gene methylation in preeclamptic placentas. Hypertens Res 34: 655-661, 2011.