Effect of PD98059, a selective MAPK3/MAPK1 inhibitor, on acute lung injury in mice

International Journal of Immunopathology and Pharmacology

Volumn 22, Issue 4, 2009, Pages 937-950

  Di Paola, R ^a   Crisafulli, C ^b   Mazzon, E ^a   Genovese, T ^a   Paterniti, I ^b   Bramanti, P ^a   Cuzzocrea, Salvatore ^a,b  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

Mitogen activated protein kinase inhibitor; Neutrophil infiltration; Pleurisy

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 NITROTYROSINE; CARRAGEENAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PADGEM PROTEIN; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LUNG FLUID; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PLEURA CAVITY; PLEURISY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCORING SYSTEM; SIGNAL TRANSDUCTION;

EID: 76349084490     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200902200409     Document Type: Article

References (32)

1. Tomlinson A, Appleton I, Moore AR, Gilroy DW, Willis D, Mitchell JA, Willoughby DA. Cyclooxygenase and nitric oxide synthase isoforms in rat carrageenin-induced pleurisy. Br J Pharmacol 1994; 113:693-8.
2. Nantel F, Denis D, Gordon R, Northey A, Cirino M, Metters KM, Chan CC. Distribution and regulation of cyclooxygenase-2 in carrageenan-induced inflammation. Br J Pharmacol 1999; 128:853-9.
3. Salvemini D, Wang ZQ, Wyatt PS, Bourdon DM, Marino MH, Manning PT, Currie MG. Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br J Pharmacol 1996; 118:829-38.
4. Cuzzocrea S, Nocentini G, Di Paola R, et al. Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation. J Immunol 2006; 177:631-41.
5. Fialkow L, Wang Y, Downey GP. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic Biol Med 2007; 42:153-64.
6. Parekh AB, Penner R. Store depletion and calcium influx. Physiol Rev 1997; 77:901-30.
7. Perez-De La Cruz V, Konigsberg M, Pedraza-Chaverri J, et al. Cytoplasmic calcium mediates oxidative damage in an excitotoxic/energetic deficit synergic model in rats. Eur J Neurosci 2008; 27:1075-85.
8. Morris CJ. Carrageenan-induced paw edema in the rat and mouse. Methods Mol Biol 2003; 225:115-21.
9. Wang MJ, Jeng KC, Kuo JS, Chen HL, Huang HY, Chen WF, Lin SZ. c-Jun N-terminal kinase and, to a lesser extent, p38 mitogen-activated protein kinase regulate inducible nitric oxide synthase expression in hyaluronan fragments-stimulated BV-2 microglia. J Neuroimmunol 2004; 146:50-62.
10. Xie Z, Smith CJ, Van Eldik LJ. Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38. Glia 2004; 45:170-9.
11. Zhang JZ, Jing L, Guo FY, Ma Y, Wang YL. Inhibitory effect of ketamine on phosphorylation of the extracellular signal-regulated kinase 1/2 following brain ischemia and reperfusion in rats with hyperglycemia. Exp Toxicol Pathol 2007; 59:227-35.
12. Cuzzocrea S, McDonald MC, Filipe HM, Costantino G, Mazzon E, Santagati S, Caputi AP, Thiemermann C. Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy. Eur J Pharmacol 2000; 390:209-22.
13. Minutoli L, Antonuccio P, Romeo C, et al. Evidence for a role of mitogen-activated protein kinase 3/mitogen-activated protein kinase in the development of testicular ischemia-reperfusion injury. Biol Reprod 2005; 73:730-6.
14. Genovese T, Esposito E, Mazzon E, Muia C, Di Paola R, Meli R, Bramanti P, Cuzzocrea S. Evidence for the role of mitogen-activated protein kinase signaling pathways in the development of spinal cord injury. J Pharmacol Exp Ther 2008; 325:100-14.
15. Mullane K. Neutrophil-platelet interactions and post-ischemic myocardial injury. Prog Clin Biol Res 1989; 301:39-51.
16. Cuzzocrea S, Sautebin L, De Sarro G, et al. Role of IL-6 in the pleurisy and lung injury caused by carrageenan. J Immunol 1999; 163:5094-104.
17. Cuzzocrea S, Riley DP, Caputi AP, Salvemini D. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharm Rev 2001; 53:135-59.
18. Bethea JR, Castro M, Keane RW, Lee TT, Dietrich WD, Yezierski RP. Traumatic spinal cord injury induces nuclear factor-kappaB activation. J Neurosci 1998; 18:3251-60.
19. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95:351-8.
20. Davis RJ. The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 1993; 268:14553-6.
21. Duan W, Chan JH, Wong CH, Leung BP, Wong WS. Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor UO126 in an asthma mouse model. J Immunol 2004; 172:7053-9.
22. Lee PJ, Zhang X, Shan P, et al. ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo. J Clin Invest 2006; 116:163-73.
23. Cuzzocrea S, Crisafulli C, Mazzon E, Esposito E, Muia C, Abdelrahman M, Di Paola R, Thiemermann C. Inhibition of glycogen synthase kinase-3beta attenuates the development of carrageenan-induced lung injury in mice. Br J Pharmacol 2006; 149:687-702.
24. Bowie A, O'Neill LA. Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries. Biochem Pharmacol 2000; 59:13-23.
25. Verma IM. Nuclear factor (NF)-kappaB proteins: therapeutic targets. Ann Rheum Dis 2004; 63(S):57-61.
26. Wooley PH, Whalen JD, Chapman DL, Berger AE, Richard KA, Aspar DG, Staite ND. The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced arthritis in mice. Arthritis Rheum 1993; 36:1305-14.
27. Mukherjee P, Yang SY, Wu B, Song Z, Myers LK, Robbins PD, Wooley PH. Tumour necrosis factor receptor gene therapy affects cellular immune responses in collagen induced arthritis in mice. Ann Rheum Dis 2005; 64:1550-6.
28. Cuzzocrea S, Thiemermann C, Salvemini D. Potential therapeutic effect of antioxidant therapy in shock and inflammation. Curr Med Chem 2004; 11:1147-62.
29. Beckman JS. Oxidative damage and tyrosine . nitration from peroxynitrite. Chem Res Toxicol 1996; 9:836-44.
30. Eiserich JP, Hristova M, Cross CE, et al. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 1998; 391:393-7.
31. Virag L. Poly(ADP-ribosyl)ation in asthma and other lung diseases. Pharmacol Res 2005; 52:83-92.
32. Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 1993; 151:2132-41.