Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice

Critical Care Medicine

Volumn 36, Issue 9, 2008, Pages 2621-2628

  Leite Junior, José Henrique P ^a   Garcia, Cristiane S N B ^a   Souza Fernandes, Alba B ^a   Silva, Pedro L ^a   Ornellas, Debora S ^a   Larangeira, Andrea P ^b   Castro Faria Neto, Hugo C ^b   Morales, Marcelo M ^a   Negri, Elnara M ^c   Capelozzi, Vera L ^c   Zin, Walter A ^a   Pelosi, Paolo ^d   Bozza, Patricia T ^b   Rocco, Patricia R M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Collagen; Cytokines; Electron microscopy; Inflammation; Lung mechanics

Indexed keywords

COLLAGEN FIBER; GAMMA INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; METHYLPREDNISOLONE; MIGRATION INHIBITION FACTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; AUTACOID; FIBRILLAR COLLAGEN;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; ESCHERICHIA COLI; FIBRIN FORMATION; GENE EXPRESSION; IMMUNE RESPONSE; INFLAMMATION; LUNG COMPLIANCE; LUNG CONGESTION; LUNG LAVAGE; LUNG MECHANICS; LUNG PARENCHYMA; LUNG PRESSURE; LUNG RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RIBONUCLEASE PROTECTION ASSAY; STEROID THERAPY; TISSUE REGENERATION; VISCOELASTICITY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL; ATELECTASIS; BREATHING MECHANICS; CHEMISTRY; CYTOLOGY; DRUG EFFECT; LUNG; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RANDOMIZATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ATELECTASIS; BRONCHOALVEOLAR LAVAGE FLUID; FIBRILLAR COLLAGENS; INFLAMMATION MEDIATORS; LUNG; METHYLPREDNISOLONE; MICE; MICE, INBRED BALB C; RANDOM ALLOCATION; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY MECHANICS;

EID: 53049084249     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181847b43     Document Type: Article

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