메뉴 건너뛰기




Volumn 44, Issue 5, 2012, Pages 311-318

Ginkgo biloba extract (GbE) enhances the anti-atherogenic effect of cilostazol by inhibiting ROS generation

Author keywords

Animal; Atherosclerosis; Cilostazol; Cytokines; Disease models; Ginkgo biloba; Inflammation; Macrophages; Reactive oxygen species

Indexed keywords

APOLIPOPROTEIN E; CELL ADHESION MOLECULE; CILOSTAZOL; CYTOKINE; GINKGO BILOBA EXTRACT; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84861594528     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2012.44.5.035     Document Type: Article
Times cited : (17)

References (35)
  • 1
    • 32244441864 scopus 로고    scopus 로고
    • Ginkgo biloba extract regulates differentially the cell death induced by hydrogen peroxide and simvastatin
    • Altiok N, Ersoz M, Karpuz V, Koyuturk M. Ginkgo biloba extract regulates differentially the cell death induced by hydrogen peroxide and simvastatin. Neurotoxicology 2006;27:158-63
    • (2006) Neurotoxicology , vol.27 , pp. 158-163
    • Altiok, N.1    Ersoz, M.2    Karpuz, V.3    Koyuturk, M.4
  • 2
    • 77953335543 scopus 로고    scopus 로고
    • Anti-inflammatory role of cilostazol in vascular smooth muscle cells in vitro and in vivo
    • Aoki C, Hattori Y, Tomizawa A, Jojima T, Kasai K. Anti-inflammatory role of cilostazol in vascular smooth muscle cells in vitro and in vivo. J Atheroscler Thromb 2010;17:503-9
    • (2010) J Atheroscler Thromb , vol.17 , pp. 503-509
    • Aoki, C.1    Hattori, Y.2    Tomizawa, A.3    Jojima, T.4    Kasai, K.5
  • 3
    • 0041689955 scopus 로고    scopus 로고
    • Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells
    • Chen JW, Chen YH, Lin FY, Chen YL, Lin SJ. Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells. Arterioscler Thromb Vasc Biol 2003;23: 1559-66
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1559-1566
    • Chen, J.W.1    Chen, Y.H.2    Lin, F.Y.3    Chen, Y.L.4    Lin, S.J.5
  • 6
    • 77951968184 scopus 로고    scopus 로고
    • Macronutrient intake induces oxidative and inflammatory stress: Potential relevance to atherosclerosis and insulin resistance
    • Dandona P, Ghanim H, Chaudhuri A, Dhindsa S, Kim SS. Macronutrient intake induces oxidative and inflammatory stress: potential relevance to atherosclerosis and insulin resistance. Exp Mol Med 2010;42:245-53
    • (2010) Exp Mol Med , vol.42 , pp. 245-253
    • Dandona, P.1    Ghanim, H.2    Chaudhuri, A.3    Dhindsa, S.4    Kim, S.S.5
  • 7
    • 70350513170 scopus 로고    scopus 로고
    • Medical treatment of patients with intracranial atherosclerotic disease
    • Gomez CR, Qureshi AI. Medical treatment of patients with intracranial atherosclerotic disease. J Neuroimaging 2009; 19:25S-9S
    • (2009) J Neuroimaging , vol.19
    • Gomez, C.R.1    Qureshi, A.I.2
  • 8
    • 57749183407 scopus 로고    scopus 로고
    • Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMPactivated protein kinase activation in vascular endothelial cells
    • Hattori Y, Suzuki K, Tomizawa A, Hirama N, Okayasu T, Hattori S, Satoh H, Akimoto K, Kasai K. Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMPactivated protein kinase activation in vascular endothelial cells. Cardiovasc Res 2009;81:133-9
    • (2009) Cardiovasc Res , vol.81 , pp. 133-139
    • Hattori, Y.1    Suzuki, K.2    Tomizawa, A.3    Hirama, N.4    Okayasu, T.5    Hattori, S.6    Satoh, H.7    Akimoto, K.8    Kasai, K.9
  • 9
    • 33846586683 scopus 로고    scopus 로고
    • The Ginkgo biloba extract EGb761 reduces stress sensitivity, ROS accumulation and expression of catalase and glutathione S-transferase 4 in Caenorhabditis elegans
    • Kampkotter A, Pielarski T, Rohrig R, Timpel C, Chovolou Y, Watjen W, Kahl R. The Ginkgo biloba extract EGb761 reduces stress sensitivity, ROS accumulation and expression of catalase and glutathione S-transferase 4 in Caenorhabditis elegans. Pharmacol Res 2007;55:139-47
    • (2007) Pharmacol Res , vol.55 , pp. 139-147
    • Kampkotter, A.1    Pielarski, T.2    Rohrig, R.3    Timpel, C.4    Chovolou, Y.5    Watjen, W.6    Kahl, R.7
  • 10
    • 0036156874 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced apoptosis by cilostazol in human umbilical vein endothelial cells
    • Kim KY, Shin HK, Choi JM, Hong KW. Inhibition of lipopolysaccharide-induced apoptosis by cilostazol in human umbilical vein endothelial cells. J Pharmacol Exp Ther 2002;300:709-15
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 709-715
    • Kim, K.Y.1    Shin, H.K.2    Choi, J.M.3    Hong, K.W.4
  • 11
    • 33747183132 scopus 로고    scopus 로고
    • Protection from apoptotic cell death by cilostazol, phosphodiesterase type III inhibitor, via cAMP-dependent protein kinase activation
    • Kim MJ, Lee JH, Park SY, Hong KW, Kim CD, Kim KY, Lee WS. Protection from apoptotic cell death by cilostazol, phosphodiesterase type III inhibitor, via cAMP-dependent protein kinase activation. Pharmacol Res 2006;54:261-7
    • (2006) Pharmacol Res , vol.54 , pp. 261-267
    • Kim, M.J.1    Lee, J.H.2    Park, S.Y.3    Hong, K.W.4    Kim, C.D.5    Kim, K.Y.6    Lee, W.S.7
  • 12
    • 20944448650 scopus 로고    scopus 로고
    • Cilostazol reduces atherosclerosis by inhibition of superoxide and tumor necrosis factor-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol
    • Lee JH, Oh GT, Park SY, Choi JH, Park JG, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW. Cilostazol reduces atherosclerosis by inhibition of superoxide and tumor necrosis factor-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol. J Pharmacol Exp Ther 2005;313: 502-9
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 502-509
    • Lee, J.H.1    Oh, G.T.2    Park, S.Y.3    Choi, J.H.4    Park, J.G.5    Kim, C.D.6    Lee, W.S.7    Rhim, B.Y.8    Shin, Y.W.9    Hong, K.W.10
  • 13
    • 0034813229 scopus 로고    scopus 로고
    • Differential lipogenic effects of cilostazol and pentoxifylline in patients with intermittent claudication: Potential role for interleukin-6
    • Lee TM, Su SF, Hwang JJ, Tseng CD, Chen MF, Lee YT, Wang SS. Differential lipogenic effects of cilostazol and pentoxifylline in patients with intermittent claudication: potential role for interleukin-6. Atherosclerosis 2001;158: 471-6
    • (2001) Atherosclerosis , vol.158 , pp. 471-476
    • Lee, T.M.1    Su, S.F.2    Hwang, J.J.3    Tseng, C.D.4    Chen, M.F.5    Lee, Y.T.6    Wang, S.S.7
  • 14
    • 67650716517 scopus 로고    scopus 로고
    • Cilostazol protects endothelial cells against lipopolysaccharide-induced apoptosis through ERK1/2-and P38 MAPK-dependent pathways
    • Lim JH, Woo JS, Shin YW. Cilostazol protects endothelial cells against lipopolysaccharide-induced apoptosis through ERK1/2-and P38 MAPK-dependent pathways. Korean J Intern Med 2009;24:113-22
    • (2009) Korean J Intern Med , vol.24 , pp. 113-122
    • Lim, J.H.1    Woo, J.S.2    Shin, Y.W.3
  • 15
    • 36049037333 scopus 로고    scopus 로고
    • Ginkgo biloba, inflammation and lipoprotein(a)
    • Lippi G, Targher G, Guidi GC. Ginkgo biloba, inflammation and lipoprotein(a). Atherosclerosis 2007;195:417-8
    • (2007) Atherosclerosis , vol.195 , pp. 417-418
    • Lippi, G.1    Targher, G.2    Guidi, G.C.3
  • 16
    • 59649089829 scopus 로고    scopus 로고
    • Inhibitions of vascular endothelial growth factor expression and foam cell formation by EGb 761, a special extract of Ginkgo biloba, in oxidatively modified low-density lipoprotein-induced human THP-1 monocytes cells
    • Liu HJ, Wang XL, Zhang L, Qiu Y, Li TJ, Li R, Wu MC, Wei LX, Rui YC. Inhibitions of vascular endothelial growth factor expression and foam cell formation by EGb 761, a special extract of Ginkgo biloba, in oxidatively modified low-density lipoprotein-induced human THP-1 monocytes cells. Phytomedicine 2009;16:138-45
    • (2009) Phytomedicine , vol.16 , pp. 138-145
    • Liu, H.J.1    Wang, X.L.2    Zhang, L.3    Qiu, Y.4    Li, T.J.5    Li, R.6    Wu, M.C.7    Wei, L.X.8    Rui, Y.C.9
  • 17
    • 82955176467 scopus 로고    scopus 로고
    • Role of cilostazol in alleviating cardiovascular complications induced in experimental rats through regulation of type 1 plasminogen activator inhibitor and transforming growth factor-beta(1) overexpression
    • Mohamed RH. Role of cilostazol in alleviating cardiovascular complications induced in experimental rats through regulation of type 1 plasminogen activator inhibitor and transforming growth factor-beta(1) overexpression. Biomed Pharmacother 2009;12:12
    • (2009) Biomed Pharmacother , vol.12 , pp. 12
    • Mohamed, R.H.1
  • 21
    • 51649106480 scopus 로고    scopus 로고
    • Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells
    • Ota H, Eto M, Kano MR, Ogawa S, Iijima K, Akishita M, Ouchi Y. Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells. Arterioscler Thromb Vasc Biol 2008;28:1634-9
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1634-1639
    • Ota, H.1    Eto, M.2    Kano, M.R.3    Ogawa, S.4    Iijima, K.5    Akishita, M.6    Ouchi, Y.7
  • 22
    • 0034904647 scopus 로고    scopus 로고
    • Cilostazol represses vascular cell adhesion molecule-1 gene transcription via inhibiting NF-kappaB binding to its recognition sequence
    • Otsuki M, Saito H, Xu X, Sumitani S, Kouhara H, Kurabayashi M, Kasayama S. Cilostazol represses vascular cell adhesion molecule-1 gene transcription via inhibiting NF-kappaB binding to its recognition sequence. Atherosclerosis 2001; 158:121-8
    • (2001) Atherosclerosis , vol.158 , pp. 121-128
    • Otsuki, M.1    Saito, H.2    Xu, X.3    Sumitani, S.4    Kouhara, H.5    Kurabayashi, M.6    Kasayama, S.7
  • 23
    • 66349092844 scopus 로고    scopus 로고
    • Ginkgo biloba extract attenuates oxLDL-induced oxidative functional damages in endothelial cells
    • Ou HC, Lee WJ, Lee IT, Chiu TH, Tsai KL, Lin CY, Sheu WH. Ginkgo biloba extract attenuates oxLDL-induced oxidative functional damages in endothelial cells. J Appl Physiol 2009;106:1674-85
    • (2009) J Appl Physiol , vol.106 , pp. 1674-1685
    • Ou, H.C.1    Lee, W.J.2    Lee, I.T.3    Chiu, T.H.4    Tsai, K.L.5    Lin, C.Y.6    Sheu, W.H.7
  • 24
    • 52249121365 scopus 로고    scopus 로고
    • Synergistic efficacy of concurrent treatment with cilostazol and probucol on the suppression of reactive oxygen species and inflammatory markers in cultured human coronary artery endothelial cells
    • Park SY, Lee JH, Shin HK, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW. Synergistic efficacy of concurrent treatment with cilostazol and probucol on the suppression of reactive oxygen species and inflammatory markers in cultured human coronary artery endothelial cells. Korean J Physiol Pharmacol 2008;12:165-70
    • (2008) Korean J Physiol Pharmacol , vol.12 , pp. 165-170
    • Park, S.Y.1    Lee, J.H.2    Shin, H.K.3    Kim, C.D.4    Lee, W.S.5    Rhim, B.Y.6    Shin, Y.W.7    Hong, K.W.8
  • 25
    • 0027246226 scopus 로고
    • inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1
    • Pober JS, Slowik MR, De Luca LG, Ritchie AJ. Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1. J Immunol 1993;150:5114-23
    • (1993) J Immunol , vol.150 , pp. 5114-5123
    • Pober, J.S.1    Slowik, M.R.2    de Luca, L.G.3    Ritchie, A.J.4    Elevated cyclic, A.M.P.5
  • 26
  • 27
    • 34248218053 scopus 로고    scopus 로고
    • Reduction of atherosclerotic nanoplaque formation and size by Ginkgo biloba (EGb 761) in cardiovascular high-risk patients
    • Rodriguez M, Ringstad L, Schafer P, Just S, Hofer HW, Malmsten M, Siegel G. Reduction of atherosclerotic nanoplaque formation and size by Ginkgo biloba (EGb 761) in cardiovascular high-risk patients. Atherosclerosis 2007; 192:438-44
    • (2007) Atherosclerosis , vol.192 , pp. 438-444
    • Rodriguez, M.1    Ringstad, L.2    Schafer, P.3    Just, S.4    Hofer, H.W.5    Malmsten, M.6    Siegel, G.7
  • 28
    • 67649933940 scopus 로고    scopus 로고
    • Ginkgo biloba extract enhances antiplatelet and antithrombotic effects of cilostazol without prolongation of bleeding time
    • Ryu KH, Han HY, Lee SY, Jeon SD, Im GJ, Lee BY, Kim K, Lim KM, Chung JH. Ginkgo biloba extract enhances antiplatelet and antithrombotic effects of cilostazol without prolongation of bleeding time. Thromb Res 2009;124: 328-34
    • (2009) Thromb Res , vol.124 , pp. 328-334
    • Ryu, K.H.1    Han, H.Y.2    Lee, S.Y.3    Jeon, S.D.4    Im, G.J.5    Lee, B.Y.6    Kim, K.7    Lim, K.M.8    Chung, J.H.9
  • 29
    • 55349128517 scopus 로고    scopus 로고
    • Medical management and cardiovascular risk reduction in peripheral arterial disease
    • Sethi A, Arora RR. Medical management and cardiovascular risk reduction in peripheral arterial disease. Exp Clin Cardiol 2008;13:113-9
    • (2008) Exp Clin Cardiol , vol.13 , pp. 113-119
    • Sethi, A.1    Arora, R.R.2
  • 30
    • 1442335807 scopus 로고    scopus 로고
    • Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase-mediated production of superoxide and cytokines via lectin-like oxidized low-density lipoprotein receptor-1 activation: Prevention by cilostazol
    • Shin HK, Kim YK, Kim KY, Lee JH, Hong KW. Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase-mediated production of superoxide and cytokines via lectin-like oxidized low-density lipoprotein receptor-1 activation: prevention by cilostazol. Circulation 2004;109:1022-8
    • (2004) Circulation , vol.109 , pp. 1022-1028
    • Shin, H.K.1    Kim, Y.K.2    Kim, K.Y.3    Lee, J.H.4    Hong, K.W.5
  • 32
    • 0344741545 scopus 로고    scopus 로고
    • Reduction of remnant lipoprotein cholesterol concentrations by cilostazol in patients with intermittent claudication
    • Wang T, Elam MB, Forbes WP, Zhong J, Nakajima K. Reduction of remnant lipoprotein cholesterol concentrations by cilostazol in patients with intermittent claudication. Atherosclerosis 2003;171:337-42
    • (2003) Atherosclerosis , vol.171 , pp. 337-342
    • Wang, T.1    Elam, M.B.2    Forbes, W.P.3    Zhong, J.4    Nakajima, K.5
  • 33
    • 0032732971 scopus 로고    scopus 로고
    • Ginkgo biloba inhibits hydrogen peroxide-induced activation of nuclear factor kappa B in vascular endothelial cells
    • Wei Z, Peng Q, Lau BH, Shah V. Ginkgo biloba inhibits hydrogen peroxide-induced activation of nuclear factor kappa B in vascular endothelial cells. Gen Pharmacol 1999;33:369-75
    • (1999) Gen Pharmacol , vol.33 , pp. 369-375
    • Wei, Z.1    Peng, Q.2    Lau, B.H.3    Shah, V.4
  • 34
    • 67649383504 scopus 로고    scopus 로고
    • Cilostazol Attenuates 4-hydroxynonenal-enhanced CD36 Expression on Murine Macrophages via Inhibition of NADPH Oxidase-derived Reactive Oxygen Species Production
    • Yun MR, Park HM, Seo KW, Kim CE, Yoon JW, Kim CD. Cilostazol Attenuates 4-hydroxynonenal-enhanced CD36 Expression on Murine Macrophages via Inhibition of NADPH Oxidase-derived Reactive Oxygen Species Production. Korean J Physiol Pharmacol 2009;13:99-106
    • (2009) Korean J Physiol Pharmacol , vol.13 , pp. 99-106
    • Yun, M.R.1    Park, H.M.2    Seo, K.W.3    Kim, C.E.4    Yoon, J.W.5    Kim, C.D.6
  • 35
    • 0034088256 scopus 로고    scopus 로고
    • Reactive oxygen species-induced apoptosis in PC12 cells and protective effect of bilobalide
    • Zhou LJ, Zhu XZ. Reactive oxygen species-induced apoptosis in PC12 cells and protective effect of bilobalide. J Pharmacol Exp Ther 2000;293:982-8
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 982-988
    • Zhou, L.J.1    Zhu, X.Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.