The protective effects of intratympanic dexamethasone and vitamin e on cisplatin-induced ototoxicity are demonstrated in rats

Medical Oncology

Volumn 28, Issue 2, 2011, Pages 615-621

  Paksoy, Mustafa ^a   Ayduran, Emin ^b   Şanlı, Arif ^a   Eken, Mehmet ^a   Aydın, Sedat ^a   Oktay, Zeynep Alev ^c  

^a Kartal Training and Research Hospital   (Turkey)

^b Irnak Army Hospital   (Turkey)

^c Department of Obstetrics and Gynecology Bulancak Government Hospital   (Turkey)

Author keywords

Cisplatin; Dexamethasone; ntratympanic otoprotection; Ototoxicity; Rat; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; CISPLATIN; DEXAMETHASONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY THRESHOLD; CONTROLLED STUDY; EAR PROTECTION; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; HEARING LOSS; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; RAT;

EID: 85027922952     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9477-4     Document Type: Article

References (36)

1. M Sakamoto K Kaga T Kamio 2000 Extended high-frequency ototoxicity induced by the first administration of cisplatin Otolaryngol Head Neck Surg 122 828 833 10828794 10.1016/S0194-5998(00)70009-X 1:STN:280:DC%2BD3c3ptFarsQ%3D%3D (Pubitemid 30412647)
2. ME Cooley L Davis J Abrahm 1994 Cisplatin: a clinical review. Part II-Nursing assessment and management of side effects of cisplatin Cancer Nurs 17 283 293 7954376 1:STN:280:DyaK2M%2Fkt1aktA%3D%3D (Pubitemid 24255418)
3. G Laurell D Bagger-Sjoback 1991 Dose-dependent inner ear changes after i.v. administration of cisplatin J Otolaryngol 20 158 167 1870163 1:STN:280:DyaK3Mzjt12ltw%3D%3D
4. MA Teranishi T Nakashima 2003 Effects of trolox, locally applied on round windows, on cisplatin-induced ototoxicity in guinea pigs Int J Pediatr Otorhinolaryngol 67 2 133 139 12623149 10.1016/S0165-5876(02)00353-1 (Pubitemid 36298690)
5. AR Fetoni N Quaranta R Marchese G Cadoni G Paludetti B Sergi 2004 The protective role of tiopronin in cisplatin ototoxicity in Wistar rats Int J Audiol 43 8 465 470 15643740 10.1080/14992020400050059 (Pubitemid 39472940)
6. M Takumida M Anniko 2001 Nitric oxide in guinea pig vestibular sensory cells following gentamicin exposure in vitro Acta Otolaryngol 121 346 350 11425199 10.1080/000164801300366589 1:CAS:528:DC%2BD38XlsFOmsbg%3D (Pubitemid 32472988)
7. KI Watanabe A Hess W Bloch O Michel 2000 Nitric oxide synthase inhibitor suppresses the ototoxic side effect of cisplatin in guinea pigs Anticancer Drugs 11 5 401 406 10912957 10.1097/00001813-200006000-00011 1:CAS:528: DC%2BD3cXltVegtbs%3D (Pubitemid 30459476)
8. LP Rybak K Husain C Morris C Whitworth S Somani 2000 Effect of protective agents against cisplatin ototoxicity Am J Otol 21 513 520 10912697 1:STN:280:DC%2BD3M%2FivVaiuw%3D%3D (Pubitemid 30432460)
9. C Wimmer K Mees P Stumpf, et al. 2004 Round window application of D-methionine, sodium thiosulfate, brain-derived neurotrophic factor, and fibroblast growth factor-2 in cisplatin-induced ototoxicity OtolNeurotol 25 33 40 (Pubitemid 39077568)
10. RD Kopke W Liu R Gabaizadeh, et al. 1997 Use of organotypic cultures ofCorti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells Am J Otol 18 559 571 9303151 1:STN:280:DyaK2svkvVyhtA%3D%3D (Pubitemid 27428342)
11. H Ito T Okafuji T Suzuki 1995 Vitamin E prevents endothelial injury associated with cisplatin injection into the superior mesenteric artery of rats Heart Vessels 10 178 184 8530321 10.1007/BF01744983 1:STN:280: DyaK28%2FovFGnug%3D%3D
12. N Dehne J Lautermann F Petrat U Rauen H de Groot 2001 Cisplatin ototoxicity: involvement of iron and enhanced formation of superoxide anion radicals Toxicol Appl Pharmacol 174 27 34 11437646 10.1006/taap.2001.9171 1:CAS:528:DC%2BD3MXkvVOku7Y%3D (Pubitemid 32635003)
13. NI Weijl GD Hopman A Wipkink-Bakker, et al. 1998 Cisplatin combination chemotherapy induces a fall in plasma antioxidants of cancer patients Ann Oncol 9 1331 1337 9932164 10.1023/A:1008407014084 1:STN:280:DyaK1M7jtV2mtA%3D%3D 14-10 (Pubitemid 29045573)
14. JG Kalkanis C Whitworth LP Rybak 2004 Vitamin E reduces cisplatin ototoxicity Laryngoscope 114 3 538 542 15091231 10.1097/00005537-200403000-00028 1:CAS:528:DC%2BD2cXivFKjsrc%3D (Pubitemid 38391921)
15. CA Hargunani JB Kempton JM DeGagne DR Trune 2006 Intratympanic injection of dexamethasone: time course of inner ear distribution and conversion to its active form Otol Neurotol 27 564Y9 10.1097/00129492-200606000-00021
16. C Himeno M Komeda M Izumikawa, et al. 2002 Intra-cochlear administration of dexamethasone attenuates aminoglycoside ototoxicity in the guinea pig Hear Res 67 61Y70
17. SS Chandrasekhar RY Rubinstein JA Kwartler, et al. 2000 Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents Otolaryngol Head Neck Surg 122 521Y8 10.1016/S0194-5998(00)70094-5
18. UI Tuor 1997 Glucocorticoids and the prevention of hypoxic-ischemic brain damage Neurosci Biobehav Rev 21 2 175 179 9062940 10.1016/S0149-7634(96)00007-3 1:CAS:528:DyaK2sXitFWgu74%3D (Pubitemid 27102562)
19. RM Palmer L Bridge NA Foxwell, et al. 1992 The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids Br J Pharmacol 105 11 12 1596673 1:CAS:528:DyaK38XitFaksLw%3D
20. M Nagura S Iwasaki R Wu, et al. 1999 Effects of corticosteroid, contrast medium and ATP on focal microcirculatory disorders of the cochlea Eur J Pharmacol 366 47Y53 10.1016/S0014-2999(98)00881-4 (Pubitemid 29076720)
21. I Herr E Ucur K Herzer, et al. 2003 Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas Cancer Res 63 3112Y20
22. LS Parnes AH Sun DJ Freeman 1999 Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application Laryngoscope 109 1Y17 10.1097/00005537-199907001-00001
23. KJ Doyle C Bauch R Battista, et al. 2004 Intratympanic steroid treatment: a review Otol Neurotol 25 1034Y9
24. PA Bird EJ Begg M Zhang AT Keast DP Murray TJ Balkany 2007 Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph Otol Neurotol 28 1124Y30 10.1097/MAO.0b013e31815aee21 (Pubitemid 350191089)
25. J Kolls J Xie R LeBlanc, et al. 1994 Rapid induction of messenger RNA for nitric oxide synthase II in rat neutrophils in vivo by endotoxin and its suppression by prednisolone Proc Soc Exp Biol Med 205 220Y9
26. J Wang RV Lloyd Faulconbridge A Fetoni, et al. 2003 Local application of sodium thiosulfate prevents cisplatin-induced hearing loss in the guinea pig Neuropharmacology 45 380 393 12871655 10.1016/S0028-3908(03)00194-1 1:CAS:528:DC%2BD3sXlsVWksrs%3D (Pubitemid 36836134)
27. SB Minami SH Sha J Schacht 2004 Antioxidant protection in a new animal model of cisplatin-induced ototoxicity Hear Res 198 137 143 15567610 10.1016/j.heares.2004.07.016 1:CAS:528:DC%2BD2cXhtVSktrjE (Pubitemid 39536163)
28. JG Feghali W Liu TR Van De Water 2001 L-n-acetyl-cysteine protection against cisplatin- induced auditory neuronal and hair cell toxicity Laryngoscope 111 7 1147 1155 11568534 10.1097/00005537-200107000-00005 1:CAS:528: DC%2BD3MXlt1ylsLc%3D (Pubitemid 32625400)
29. DT Dickey LL Muldoon DF Kraemer EA Neuwelt 2004 Protection against cisplatin induced ototoxicity by N-acetylcysteine in a rat model Hear Res 193 25 30 10.1016/j.heares.2004.02.007 (Pubitemid 38813422)
30. WT Choe N Chinosornvatana KW Chang 2004 Prevention of cisplatin ototoxicity using transtympanic N-acetylcysteine and lactate Otol Neurotol 25 6 910 915 15547419 10.1097/00129492-200411000-00009 (Pubitemid 39491671)
31. H Silverstein JE Isaacson MJ Olds, et al. 1998 Dexamethasone inner ear perfusion for the treatment of Meniere's disease: a prospective, randomized, double-blind, crossover trial Am J Otol 19 196 201 9520056 1:STN:280: DyaK1c7nvVykug%3D%3D (Pubitemid 28152576)
32. A Daldal O OdabaşI B serbetcioǧlu 2007 The protective effect of intratympanic dexamethasone on cisplatin-induced ototoxicity in guinea pigs Otolaryngol Head Neck Surg 137 5 747 752 17967639 10.1016/j.otohns.2007. 05.068 (Pubitemid 47632918)
33. GW Hill DK Morest K Parham 2008 Cisplatin-induced ototoxicity: effect of intratympanic dexamethasone injections Otol Neurotol 29 7 1005 1011 18716567 10.1097/MAO.0b013e31818599d5
34. C Zhang A Marme T Wenger, et al. 2006 Glucocorticoid-mediated inhibition of chemotherapy in ovarian carcinomas Int J Oncol 28 551 558 16391812
35. C Leonetti A Biroccio C Gabellini, et al. 2003 Alpha-tocopherol protects against cisplatin-induced toxicity without interfering with antitumor efficacy Int J Cancer 104 243 250 12569582 10.1002/ijc.10933 1:CAS:528: DC%2BD3sXhvFyktLw%3D (Pubitemid 36249802)
36. S Sarna A Kumar RK Bhola 2000 Alpha-tocopherol enhances tumor growth inhibition by cis-dichlorodiammine platinum (II) Braz J Med Biol Res 33 929 993 10920435 10.1590/S0100-879X2000000800009 1:CAS:528:DC%2BD3cXmsFOlsLo%3D