Biosynthesis of highly enriched 13C-lycopene for human metabolic studies using repeated batch tomato cell culturing with 13C-glucose

Food Chemistry

Volumn 139, Issue 1-4, 2013, Pages 631-639

  Moran, Nancy Engelmann ^a   Rogers, Randy B ^b   Lu, Chi Hua ^b   Conlon, Lauren E ^b   Lila, Mary Ann ^b,c   Clinton, Steven K ^a   Erdman Jr , John W ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Carotenoids; Lycopene; Nutrition; Plant cell culture; Tomato; Tracers

Indexed keywords

CAROTENOIDS; HEXANE EXTRACTION; ISOTOPOMERS; LYCOPENES; REPEATED BATCH; SOLANUM LYCOPERSICUM; TOMATO; TOMATO CELLS;

ACETONE; BIOCHEMISTRY; EXTRACTION; GLUCOSE; ISOTOPES; LOADING; MAMMALS; METABOLISM; NUTRITION; PHYSIOLOGY; PLANT CELL CULTURE; RADIOACTIVE TRACERS;

FRUITS;

CARBON 13; GLUCOSE; LYCOPENE;

ADAPTATION; ARTICLE; BIOAVAILABILITY; BIOSYNTHESIS; CARBON FIXATION; CONTROLLED STUDY; PLANT CELL CULTURE; TOMATO;

BIOLOGICAL AVAILABILITY; CARBON ISOTOPES; CAROTENOIDS; CELLS, CULTURED; GLUCOSE; HUMANS; ISOTOPE LABELING; LYCOPERSICON ESCULENTUM;

LYCOPERSICON ESCULENTUM; MAMMALIA;

EID: 84875959025     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.01.016     Document Type: Article

References (37)

1. M.E. Auldridge, D.R. McCarty, and H.J. Klee Plant carotenoid cleavage oxygenases and their apocarotenoid products Current Opinion in Plant Biology 9 3 2006 315 321
2. 14C-phytoene from tomato cell suspension cultures (Lycopersicon esculentum) for utilisation in prostate cancer cell culture studies Journal of Agricultural and Food Chemistry 54 3 2006 747 755
3. K. Canene-Adams, J.K. Campbell, S. Zaripheh, E.H. Jeffery, and J.W. Erdman Jr. The tomato as a functional food The Journal of Nutrition 135 5 2005 1226 1230
4. N.J. Engelmann, J.K. Campbell, R.B. Rogers, S.I. Rupassara, P.J. Garlick, and M.A. Lila Screening and selection of high carotenoid producing in vitro tomato cell culture lines for [(13)C]-carotenoid production Journal of Agricultural and Food Chemistry 58 18 2010 9979 9987
5. N.J. Engelmann, S.K. Clinton, and J.W. Erdman Jr. Nutritional aspects of phytoene and phytofluene, carotenoid precursors to lycopene Advances in Nutrition (Bethesda, Md.) 2 1 2011 51 61
6. N.J. Engelmann, A. Reppert, G. Yousef, R.B. Rogers, and M.A. Lila In vitro production of radiolabelled red clover (Trifolium pratense) isoflavones Plant Cell, Tissue and Organ Culture 98 2 2009 147 156
7. 14C tracer production from tomato (Solanum lycopersicum cv. VFNT cherry) cell cultures Journal of Agricultural and Food Chemistry 57 11 2009 4614 4619
8. N.A. Ford, S.K. Clinton, J. von Lintig, A. Wyss, and J.W. Erdman Jr. Loss of carotene-9′,10′-monooxygenase expression increases serum and tissue lycopene concentrations in lycopene-fed mice The Journal of Nutrition 140 12 2010 2134
9. E. Giovannucci, A. Ascherio, E.B. Rimm, M.J. Stampfer, G.A. Colditz, and W.C. Willett Intake of carotenoids and retinol in relation to risk of prostate cancer Journal of the National Cancer Institute 87 23 1995 1767 1776
10. 14C-enrichment of phytochemicals in plant cell suspension cultures In Vitro Cellular and Developmental Biology Plant 40 1 2004 80 85
11. S.J. Ha, J.M. Galazka, S.R. Kim, J.H. Choi, X. Yang, and J.H. Seo Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation Proceedings of the National Academy of Sciences of the United States of America 108 2 2011 504 509
12. 13C-labeled and endogenous beta-carotene, lutein, and vitamin A in human plasma Lipids 36 11 2001 1277 1282
13. F. Khachik, L. Carvalho, P.S. Bernstein, G.J. Muir, D.Y. Zhao, and N.B. Katz Chemistry, distribution, and metabolism of tomato carotenoids and their impact on human health Experimental Biology and Medicine (Maywood, N.J.) 227 10 2002 845 851
14. R.E. Kopec, K.M. Riedl, E.H. Harrison, R.W. Curley, D.P. Hruszkewycz, and S.K. Clinton Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma Journal of Agricultural and Food Chemistry 58 6 2010 3290 3296
15. 13C-labelled anthocyanins by Vitis vinifera cell suspension cultures Phytochemistry 51 5 1999 651 656
16. M.A. Lila Anthocyanins and human health: An in vitro investigative approach Journal of Biomedicine and Biotechnology 5 2004 306
17. M.A. Lila The nature-versus-nurture debate on bioactive phytochemicals: The genome versus terroir Journal of the Science of Food and Agriculture 86 15 2006 2510 2515
18. C.H. Lu, N.J. Engelmann, M.A. Lila, and J.W. Erdman Jr. Optimization of lycopene extraction from tomato cell suspension culture by response surface methodology Journal of Agricultural and Food Chemistry 56 17 2008 7710 7714
19. 13C-labeled lycopene and phytoene by bioengineered Escherichia coli. Journal of Agricultural and Food Chemistry, 59(18), 9996.
20. N.R. Mustafa, W. de Winter, F. van Iren, and R. Verpoorte Initiation, growth and cryopreservation of plant cell suspension cultures Nature Protocols 6 6 2011 715 742
21. J.A. Novotny, A.C. Kurilich, S.J. Britz, and B.A. Clevidence Plasma appearance of labeled beta-carotene, lutein, and retinol in humans after consumption of isotopically labeled kale Journal of Lipid Research 46 9 2005 1896 1903
22. S. Ramachandra Rao, and G.A. Ravishankar Plant cell cultures: Chemical factories of secondary metabolites Biotechnology Advances 20 2 2002 101 153
23. A. Reppert, G.G. Yousef, R.B. Rogers, and M.A. Lila Isolation of radiolabeled isoflavones from kudzu (Pueraria lobata) root cultures Journal of Agricultural and Food Chemistry 56 17 2008 7860 7865
24. T. Rissanen, S. Voutilainen, K. Nyyssonen, and J.T. Salonen Lycopene, atherosclerosis, and coronary heart disease Experimental Biology and Medicine (Maywood, N.J.) 227 10 2002 900 907
25. G.H. Robertson, N.E. Mahoney, N. Goodman, and A.E. Pavlath Regulation of lycopene formation in cell suspension culture of VFNT tomato (Lycopersicon esculentum) by CPTA, growth regulators, sucrose, and temperature Journal of Experimental Botany 46 287 1995 667 673
26. D.B. Rodriguez-Amaya A guide to carotenoid analysis in foods 2001 OMNI Research ILSI Human Nutrition Institute Washington, DC
27. K. Schiedt, and S. Liaaen-Jensen Isolation and analysis G. Britton, S. Liaaen-Jensen, H. Pfander, Carotenoids: Isolation and analysis Vol. 1A 1995 Birkhauser Verlag Basel 81
28. G. Tang, A.L. Ferreira, M.A. Grusak, J. Qin, G.G. Dolnikowski, and R.M. Russell Bioavailability of synthetic and biosynthetic deuterated lycopene in humans The Journal of Nutritional Biochemistry 16 4 2005 229 235
29. G. Tang, J. Qin, G.G. Dolnikowski, R.M. Russell, and M.A. Grusak Spinach or carrots can supply significant amounts of vitamin A as assessed by feeding with intrinsically deuterated vegetables The American Journal of Clinical Nutrition 82 4 2005 821 828
30. G. Tang, J. Qin, G.G. Dolnikowski, R.M. Russell, and M.A. Grusak Golden Rice is an effective source of vitamin A The American Journal of Clinical Nutrition 89 6 2009 1776 1783
31. M. van Lieshout, C.E. West, and R.B. van Breemen Isotopic tracer techniques for studying the bioavailability and bioefficacy of dietary carotenoids, particularly beta-carotene, in humans: A review The American Journal of Clinical Nutrition 77 1 2003 12 28
32. X. Vitrac, S. Krisa, A. Decendit, J. Vercauteren, A. Nuhrich, and J.P. Monti Carbon-14 biolabelling of wine polyphenols in Vitis vinifera cell suspension cultures Journal of Biotechnology 95 1 2002 49 56
33. J. von Lintig Metabolism of carotenoids and retinoids related to vision Journal of Biological Chemistry 287 3 2012 1627 1634
34. WCRF, and AICR Summary: Food, nutrition, physical activity and the prevention of cancer: A global perspective 2007 American Institute for Cancer Research Washington, DC
35. K.J. Yeum, and R.M. Russell Carotenoid bioavailability and bioconversion Annual Review of Nutrition 22 2002 483 504
36. 14C-enriched flavonoid fractions from plant cell suspension cultures Journal of Agricultural and Food Chemistry 52 5 2004 1138 1145
37. X. Yue, W. Zhang, and M. Deng Hyper-production of C-13-labeled trans-resveratrol in Vitis vinifera suspension cell culture by elicitation and in situ adsorption Biochemical Engineering Journal 53 3 2011 292 296