Galanin receptors possibly modulate the obesity-induced change in pain threshold

Peptides

Volumn 44, Issue , 2013, Pages 55-59

  Yu, Mei ^b   Fang, Penghua ^a,b   Shi, Mingyi ^a   Zhu, Yan ^a   Sun, Yong ^b   Li, Qing ^b   Bo, Ping ^a   Zhang, Zhenwen ^a  

^a YANGZHOU UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Galanin receptor; Obesity; Pain threshold

Indexed keywords

GALANIN RECEPTOR 1; GALANIN RECEPTOR 2; OPIATE RECEPTOR;

BLOOD LEVEL; FOOD INTAKE; HUMAN; NOCICEPTION; NONHUMAN; OBESITY; PAIN THRESHOLD; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; RISK ASSESSMENT; SPINAL GANGLION; UPREGULATION; WEIGHT GAIN;

ANIMALS; GALANIN; HUMANS; NOCICEPTION; OBESITY; PAIN THRESHOLD; RECEPTORS, GALANIN;

ANIMALIA;

EID: 84875946738     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.02.015     Document Type: Review

References (80)

1. A.C. Adams, J.C. Clapham, D. Wynick, and J.R. Speakman Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference J Neuroendocrinol 20 2008 199 206 (Pubitemid 351147007)
2. E. Amy Janke, A.T. Kozak, and "The more pain I. have, the more I want to eat": obesity in the context of chronic pain Obesity (Silver Spring) 20 2012 2027 2034
3. K. An, Y. Xu, H. Yang, H.H. Shu, H.B. Xiang, and Y.K. Tian Subarachnoid transplantation of immortalized galanin-overexpressing astrocytes attenuates chronic neuropathic pain Eur J Pain 14 2010 595 601
4. M.L. Andersen, E.H. Santos, L. Seabra Mde, A.A. da Silva, and S. Tufik Evaluation of acute and chronic treatments with Harpagophytum procumbens on Freund's adjuvant-induced arthritis in rats J Ethnopharmacol 91 2004 325 330 (Pubitemid 38561131)
5. M.J. Bair, R.L. Robinson, W. Katon, and K. Kroenke Depression and pain comorbidity: a literature review Arch Intern Med 163 2003 2433 2445 (Pubitemid 37385786)
6. B. Baranowska, E. Wasilewska-Dziubińska, M. Radzikowska, A. Płonowski, and K. Roguski Neuropeptide Y, galanin, and leptin release in obese women and in women with anorexia nervosa Metabolism 46 1997 1384 1389 (Pubitemid 28053201)
7. B. Baranowska, M. Radzikowska, E. Wasilewska-Dziubinska, K. Roguski, and M. Borowiec Disturbed release of gastrointestinal peptides in anorexia nervosa and in obesity Diabetes Obes Metab 2 2000 99 103 (Pubitemid 33072164)
8. C.K. Batista, G.A. Brito, M.L. Souza, B.T. Leitão, F.Q. Cunha, and R.A. Ribeiro A model of hemorrhagic cystitis induced with acrolein in mice Braz J Med Biol Res 39 2006 1475 1481 (Pubitemid 46357863)
9. J.W. Bauer, R. Lang, M. Jakab, and B. Kofler Galanin family of peptides in skin function Cell Mol Life Sci 65 2008 1820 1825
10. K.H. Blakeman, J.X. Hao, X.J. Xu, A.S. Jacoby, J. Shine, and J.N. Crawley Hyperalgesia and increased neuropathic pain-like response in mice lacking galanin receptor 1 receptors Neuroscience 117 2003 221 227 (Pubitemid 36246519)
11. K.H. Blakeman, K. Holmberg, J.X. Hao, X.J. Xu, U. Kahl, and U. Lendahl Mice over-expressing galanin have elevated heat nociceptive threshold Neuroreport 12 2001 423 425 (Pubitemid 32114391)
12. T.A. Branchek, K.E. Smith, C. Gerald, and M.W. Walker Galanin receptor subtypes Trends Pharmacol Sci 21 2000 109 117 (Pubitemid 30114326)
13. P. Brumovsky, K. Hygge-Blakeman, M.J. Villar, M. Watanabe, Z. Wiesenfeld-Hallin, and T. Hökfelt Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse-possible implications for pain processing J Chem Neuroanat 31 2006 243 262 (Pubitemid 43668708)
14. T.J. Coderre, and P.D. Wall Ankle joint urate arthritis (AJUA) in rats: an alternative animal model of arthritis to that produced by Freund's adjuvant Pain 28 1987 379 393 (Pubitemid 17025978)
15. J.N. Crawley, M.C. Austin, S.M. Fiske, B. Martin, S. Consolo, and M. Berthold Activity of centrally administered galanin fragments on stimulation of feeding behavior and on galanin receptor binding in the rat hypothalamus J Neurosci 10 1990 3695 3700
16. J.T. Dourmashkin, G.Q. Chang, E.C. Gayles, J.O. Hill, S.K. Fried, and C. Julien Different forms of obesity as a function of diet composition Int J Obes (Lond) 29 2005 1368 1378 (Pubitemid 41679269)
17. P.H. Fang, M. Yu, Y.P. Ma, J. Li, Y.M. Sui, and M.Y. Shi Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior Neurosci Bull 27 2011 407 412
18. P. Fang, M. Yu, L. Guo, P. Bo, Z. Zhan, and M. Shi Galanin and its receptors: a novel strategy for appetite control and obesity therapy Peptides 36 2012 331 339
19. R.B. Fillingim Individual differences in pain responses Curr Rheumatol Rep 7 2005 342 347
20. S.J. Flatters, A.J. Fox, and A.H. Dickenson In vivo and in vitro effects of peripheral galanin on nociceptive transmission in naive and neuropathic states Neuroscience 116 2003 1005 1012 (Pubitemid 36262958)
21. L.B. Fu, X.B. Wang, S. Jiao, X. Wu, and L.C. Yu Antinociceptive effects of intracerebroventricular injection of the galanin receptor 1 agonist M 617 in rats Neurosci Lett 491 2011 174 176
22. X.L. Gu, Y.G. Sun, and L.C. Yu Involvement of galanin in nociceptive regulation in the arcuate nucleus of hypothalamus in rats with mononeuropathy Behav Brain Res 179 2007 331 335
23. B. He, M. Shi, L. Zhang, G. Li, L. Zhang, and H. Shao Beneficial effect of galanin on insulin sensitivity in muscle of type 2 diabetic rats Physiol Behav 103 2011 284 289
24. B. Heppelmann, S. Just, and M. Pawlak Galanin influences the mechanosensitivity of sensory endings in the rat knee joint Eur J Neurosci 12 2000 1567 1572 (Pubitemid 30258865)
25. S.A. Hobson, F.E. Holmes, N.C.H. Kerr, R.J.P. Pope, and D. Wynick Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour J Neurochem 99 2006 1000 1010 (Pubitemid 44583456)
26. C.P. Hofstetter, N.A. Holmström, J.A. Lilja, P. Schweinhardt, J. Hao, and C. Spenger Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome Nat Neurosci 8 2005 346 353 (Pubitemid 40300192)
27. F.E. Holmes, A. Bacon, R.J. Pope, P.A. Vanderplank, N.C. Kerr, and M. Sukumaran Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior Proc Natl Acad Sci USA 100 2003 6180 6185 (Pubitemid 36576951)
28. X.Y. Hua, C.S. Hayes, A. Hofer, B. Fitzsimmons, K. Kilk, and U. Langel Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5 J Pharmacol Exp Ther 308 2004 574 582 (Pubitemid 38134219)
29. R.P. Hulse, L.F. Donaldson, and D. Wynick Differential roles of galanin on mechanical and cooling responses at the primary afferent nociceptor Mol Pain 8 2012 41 61
30. R.P. Hulse, L.F. Donaldson, and D. Wynick Peripheral galanin receptor 2 as a target for the modulation of pain Pain Res Treat 2012 2012 1 8
31. R.P. Hulse, D. Wynick, and L.F. Donaldson Activation of the galanin receptor 2 in the periphery reverses nerve injury-induced allodynia Mol Pain 7 2011 26 31
32. K. Hygge-Blakeman, P. Brumovsky, J.X. Hao, X.J. Xu, T. Hökfelt, and J.N. Crawley Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury Brain Res 1025 2004 152 158 (Pubitemid 39359173)
33. H. Imbe, T. Abe, K. Okamoto, M. Sato, H. Ito, and S. Kumabe Increase of galanin-like immunoreactivity in rat hypothalamic arcuate neurons after peripheral nerve injury Neurosci Lett 368 2004 102 106 (Pubitemid 39178757)
34. W.Y. Jin, Z. Liu, D. Liu, and L.C. Yu Antinociceptive effects of galanin in the central nucleus of amygdala of rats, an involvement of opioid receptors Brain Res 1320 2010 16 21
35. B.J. Kerr, W.B. Cafferty, Y.K. Gupta, A. Bacon, D. Wynick, and S.B. McMahon Galanin knockout mice reveal nociceptive deficits following peripheral nerve injury Eur J Neurosci 12 2000 793 802 (Pubitemid 30168756)
36. S. Khimich Level of sensitivity of pain in patients with obesity Acta Chir Hung 36 1997 166 167
37. A. Kim, and T. Park Diet-induced obesity regulates the galanin-mediated signaling cascade in the adipose tissue of mice Mol Nutr Food Res 54 2010 1361 1370
38. S.H. Kim, and J.M. Chung An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat Pain 50 1992 355 363
39. L.F. Kolakowski Jr., G.P. O'Neill, A.D. Howard, S.R. Broussard, K.A. Sullivan, and S.D. Feighner Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3 J Neurochem 71 1998 2239 2251 (Pubitemid 28531233)
40. Y. Kuraishi, M. Kawamura, T. Yamaguchi, T. Houtani, S. Kawabata, and S. Futaki Intrathecal injections of galanin and its antiserum affect nociceptive response of rat to mechanical, but not thermal, stimuli Pain 44 1991 321 324
41. R. Lang, A.L. Gundlach, and B. Kofler The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease Pharmacol Ther 115 2007 177 207 (Pubitemid 47042915)
42. E. Le Maître, S.S. Barde, M. Palkovits, R. Diaz-Heijtz, and T.G. Hökfelt Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe Proc Natl Acad Sci USA 110 2013 E536 E545
43. K.L. Leibowitz, G.Q. Chang, P.S. Pamy, J.O. Hill, E.C. Gayles, and S.F. Leibowitz Weight gain model in prepubertal rats: prediction and phenotyping of obesity-prone animals at normal body weight Int J Obes (Lond) 31 2007 1210 1221 (Pubitemid 47172624)
44. L.L. Lemons, and R.G. Wiley Galanin receptor-expressing dorsal horn neurons: role in nociception Neuropeptides 45 2011 377 383
45. R. Lhasa, B.L. Richard, E.Z. Molly, J.K. Mindy, and A.D. Carol Mechanisms of association between obesity and chronic pain in the elderly Pain 152 2011 53 59
46. Y. Lian, S. Sheng, P. Fang, Y. Ma, J. Li, and Q. Shi Exercise-induced galanin release facilitated GLUT4 translocation in adipocytes of type 2 diabetic rats Pharmacol Biochem Behav 100 2012 554 559
47. J.W. Lisa, S. Ellen, N. Carolyn, A. Sandra, B. Dedra, and A. Niloofar Chronic pain, overweight, and obesity: findings from a community-based twin registry J Pain 11 2010 628 635
48. B.L. Loevinger, D. Muller, C. Alonso, and C.L. Coe Metabolic syndrome in women with chronic pain Metabolism 56 2007 87 93 (Pubitemid 44855016)
49. J.E. Low, R.F. Borch, and N.E. Sladek Conversion of 4- hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis Cancer Res 42 1982 830 837 (Pubitemid 12141180)
50. X. Lu, A. Mazarati, P. Sanna, S. Shinmei, and T. Bartfai Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity Neuropeptides 39 2005 147 152 (Pubitemid 40804575)
51. H. Lucas, M.E. McCarthy, M.K. Bigal, D. Carol, and B.L. Richard Chronic pain and obesity in the elderly: results from the Einstein aging study J Am Geriatr Soc 57 2009 115 119
52. S.A. Malin, and D.C. Molliver Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior Mol Pain 6 2010 21
53. S. Malkmus, X. Lu, T. Bartfai, T.L. Yaksh, and X.Y. Hua Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice Neuropeptides 39 2005 217 221 (Pubitemid 40804588)
54. B. Meczekalski, and A. Warenik-Szymankiewicz The role of galanin in the etiology of obesity in young girls Ginekol Pol 70 1999 328 332
55. H. Nishii, M. Nomura, H. Aono, N. Fujimoto, and T. Matsumoto Up-regulation of galanin and corticotropin-releasing hormone mRNAs in the key hypothalamic and amygdaloid nuclei in a mouse model of visceral pain Regul Pept 141 2007 105 112 (Pubitemid 46482690)
56. B.L. Peterlin, A.H. Calhoun, and F. Balzac Chronic pain perspectives: men, women, and migraine: the role of sex, hormones, obesity, and PTSD J Fam Pract 61 2012 S7 S11
57. R.J. Pope, F.E. Holmes, N.C. Kerr, and D. Wynick Characterisation of the nociceptive phenotype of suppressible galanin overexpressing transgenic mice Mol Pain 6 2010 67 73
58. N.J. Poritsanos, T.M. Mizuno, M.E. Lautatzis, and M. Vrontakis Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome Int J Obes (Lond) 33 2009 1381 1389
59. M. Racine, Y. Tousignant-Laflamme, L.A. Kloda, D. Dion, G. Dupuis, and M. Choinière A systematic literature review of 10 years of research on sex/gender and pain perception-part 2: do biopsychosocial factors alter pain sensitivity differently in women and men? Pain 153 2012 619 635
60. C. Radtke, P.M. Vogt, M. Devor, and J.D. Kocsis Keratinocytes acting on injured afferents induce extreme neuronal hyperexcitability and chronic pain Pain 148 2010 94 102
61. I. Ramzan, B.K. Wong, and G.B. Corcoran Pain sensitivity in dietary-induced obese rats Physiol Behav 54 1993 433 435 (Pubitemid 23257176)
62. C.R. Robertson, T.H. Pruess, E. Grussendorf, H.S. White, and G. Bulaj Generating orally active galanin analogues with analgesic activities ChemMedChem 7 2012 903 909
63. I. Saar, J. Runesson, I. McNamara, J. Järv, J.K. Robinson, and U. Langel Novel galanin receptor subtype specific ligands in feeding regulation Neurochem Int 58 2011 714 720
64. T.J. Shi, X.Y. Hua, X. Lu, S. Malkmus, J. Kinney, and K. Holmberg Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour Eur J Neurosci 23 2006 627 636
65. C.J. Spicher, F. Mathis, B. Degrange, P. Freund, and E.M. Rouiller Static mechanical allodynia (SMA) is a paradoxical painful hypo-aesthesia: observations derived from neuropathic pain patients treated with somatosensory rehabilitation Somatosens Mot Res 25 2008 77 92 (Pubitemid 351398390)
66. A.A. Stone, and J.E. Broderick Obesity and pain are associated in the United States Obesity (Silver Spring) 20 2012 1491 1495
67. S. Sun, Y. Yin, X. Yin, F. Cao, D. Luo, and T. Zhang Anti-nociceptive effects of Tanshinone IIA (TIIA) in a rat model of complete Freund's adjuvant (CFA)-induced inflammatory pain Brain Res Bull 88 2012 581 588
68. Y.G. Sun, J. Li, B.N. Yang, and L.C. Yu Antinociceptive effects of galanin in the rat tuberomammillary nucleus and the plasticity of galanin receptor 1 during hyperalgesia J Neurosci Res 77 2004 718 722 (Pubitemid 39194613)
69. Y.G. Sun, and L.C. Yu Interactions of galanin and opioids in nociceptive modulation in the arcuate nucleus of hypothalamus in rats Regul Pept 124 2005 37 43
70. K. Tatemoto, A. Rökaeus, H. Jörnvall, T.J. McDonald, and V. Mutt Galanin-a novel biologically active peptide from porcine intestine FEBS Lett 164 1983 124 128 (Pubitemid 14201839)
71. G.E. Tietjen, B.L. Peterlin, J.L. Brandes, F. Hafeez, S. Hutchinson, and V.T. Martin Depression and anxiety: effect on the migraine-obesity relationship Headache 47 2007 866 875 (Pubitemid 46944388)
72. S. Wang, T. Hashemi, S. Fried, A.L. Clemmons, and B.E. Hawes Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes Biochemistry 37 1998 6711 6717 (Pubitemid 28228104)
73. S. Wang, C. He, M.T. Maguire, A.L. Clemmons, R.E. Burrier, and M.F. Guzzi Genomic organization and functional characterization of the mouse GalR1 galanin receptor FEBS Lett 411 1997 225 230 (Pubitemid 27301459)
74. W. Xiong, L. Gao, A. Sapra, and L.C. Yu Antinociceptive role of galanin in the spinal cord of rats with inflammation, an involvement of opioid systems Regul Pept 132 2005 85 90 (Pubitemid 41607507)
75. S.L. Xu, J. Li, J.J. Zhang, and L.C. Yu Antinociceptive effects of galanin in the nucleus accumbens of rats Neurosci Lett 520 2012 43 46
76. X. Xu, Z. Liu, H. Liu, X. Yang, and Z. Li The effects of galanin on neuropathic pain in streptozotocin-induced diabetic rats Eur J Pharmacol 680 2012 28 33
77. X. Xu, X. Yang, P. Zhang, X. Chen, H. Liu, and Z. Li Effects of exogenous galanin on neuropathic pain state and change of galanin and its receptors in DRG and SDH after sciatic nerve-pinch injury in rat PLoS ONE 7 2012 E37621 E37628
78. X.J. Xu, T. Hökfelt, and Z. Wiesenfeld-Hallin Galanin and spinal pain mechanisms: past, present, and future EXS 102 2010 39 50
79. R.P. Yezierski The effects of age on pain sensitivity: preclinical studies Pain Med 13 2012 S27 S36
80. B. Zahorska-Markiewicz, P. Zych, and C. Kucio Pain sensitivity in obesity Acta Physiol Pol 39 1988 183 187